CN101641441A - 用于提高表达的细菌前导序列 - Google Patents

用于提高表达的细菌前导序列 Download PDF

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Publication number
CN101641441A
CN101641441A CN200880009677A CN200880009677A CN101641441A CN 101641441 A CN101641441 A CN 101641441A CN 200880009677 A CN200880009677 A CN 200880009677A CN 200880009677 A CN200880009677 A CN 200880009677A CN 101641441 A CN101641441 A CN 101641441A
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polypeptide
protein
sequence
proteins
nucleotide sequence
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Chinese (zh)
Inventor
拉塞尔·J·科尔曼
黛安娜·雷塔拉克
简·C·施奈德
托马斯·M·拉姆西尔
查尔斯·D·赫什伯格
斯泰西·L·李
索尔·里斯尼克
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Dow Global Technologies LLC
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Dow Global Technologies LLC
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Publication of CN101641441A publication Critical patent/CN101641441A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN200880009677A 2007-01-31 2008-01-30 用于提高表达的细菌前导序列 Pending CN101641441A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88747607P 2007-01-31 2007-01-31
US88748607P 2007-01-31 2007-01-31
US60/887,476 2007-01-31
US60/887,486 2007-01-31

Related Child Applications (1)

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CN2011103821798A Division CN102517280A (zh) 2007-01-31 2008-01-30 用于提高表达的细菌前导序列

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CN101641441A true CN101641441A (zh) 2010-02-03

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CN200880009677A Pending CN101641441A (zh) 2007-01-31 2008-01-30 用于提高表达的细菌前导序列
CN2011103821798A Pending CN102517280A (zh) 2007-01-31 2008-01-30 用于提高表达的细菌前导序列

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US (3) US7618799B2 (enExample)
EP (2) EP2468869B1 (enExample)
JP (3) JP5714230B2 (enExample)
KR (1) KR101491867B1 (enExample)
CN (2) CN101641441A (enExample)
AU (1) AU2008210538B2 (enExample)
BR (1) BRPI0807834A2 (enExample)
CA (1) CA2677179C (enExample)
PL (1) PL2468869T3 (enExample)
WO (1) WO2008094986A2 (enExample)

Cited By (6)

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CN102869778A (zh) * 2010-03-30 2013-01-09 菲尼克斯公司 重组毒素蛋白的高水平表达
CN107532163A (zh) * 2015-04-24 2018-01-02 味之素株式会社 蛋白质的分泌生产方法
CN110312792A (zh) * 2016-12-14 2019-10-08 瓦赫宁根大学 热稳定的Cas9核酸酶
CN110655560A (zh) * 2018-06-29 2020-01-07 复旦大学 T7噬菌体尾部纤维蛋白多肽及其应用
CN111372941A (zh) * 2017-10-27 2020-07-03 菲尼克斯公司 用于周质蛋白质表达的细菌前导序列
CN120349035A (zh) * 2025-06-25 2025-07-22 上海明诺环境科技有限公司 一种聚甲醛废水处理方法及应用

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