CN101605768A - 螯合剂 - Google Patents

螯合剂 Download PDF

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Publication number
CN101605768A
CN101605768A CNA2007800452581A CN200780045258A CN101605768A CN 101605768 A CN101605768 A CN 101605768A CN A2007800452581 A CNA2007800452581 A CN A2007800452581A CN 200780045258 A CN200780045258 A CN 200780045258A CN 101605768 A CN101605768 A CN 101605768A
Authority
CN
China
Prior art keywords
group
compound
methyl
compound according
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800452581A
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English (en)
Chinese (zh)
Inventor
塞巴斯蒂安·诺尔
阿明·莫德林格
汉斯-于尔根·韦斯特
霍斯特·凯斯勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technische Universitaet Muenchen
Original Assignee
Technische Universitaet Muenchen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technische Universitaet Muenchen filed Critical Technische Universitaet Muenchen
Publication of CN101605768A publication Critical patent/CN101605768A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNA2007800452581A 2006-12-08 2007-12-10 螯合剂 Pending CN101605768A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0624587.2A GB0624587D0 (en) 2006-12-08 2006-12-08 Chelating agent
GB0624587.2 2006-12-08

Publications (1)

Publication Number Publication Date
CN101605768A true CN101605768A (zh) 2009-12-16

Family

ID=37711827

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800452581A Pending CN101605768A (zh) 2006-12-08 2007-12-10 螯合剂

Country Status (8)

Country Link
US (1) US20100081799A1 (https=)
EP (1) EP2099776B1 (https=)
JP (2) JP5705434B2 (https=)
CN (1) CN101605768A (https=)
CA (1) CA2671788A1 (https=)
GB (1) GB0624587D0 (https=)
IN (1) IN2009CN02681A (https=)
WO (1) WO2008068516A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102898392A (zh) * 2012-09-06 2013-01-30 中国工程物理研究院核物理与化学研究所 N-乙酰氧苯基-3-[三叔丁氧甲酰基-四氮杂环十二烷基]中间体及其制备方法
CN104230832B (zh) * 2014-08-25 2018-07-27 曲靖师范学院 一种4，4’，4”，4”’-(1，4，7，10-四氮杂环十二烷-1，4，7，10-四基)四亚甲基四苯甲醛的合成方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0624587D0 (en) * 2006-12-08 2007-01-17 Univ Muenchen Tech Chelating agent
CN104307495A (zh) * 2014-10-14 2015-01-28 常州大学 一种含有四氮杂环的新型螯合树脂及其制备方法
EP3600452B1 (en) * 2017-03-30 2024-09-04 Cornell University Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
CA3062538A1 (en) * 2017-05-05 2018-11-08 Fusion Pharmaceuticals Inc. Igf-1r monoclonal antibodies and uses thereof
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
KR102612882B1 (ko) 2017-05-05 2023-12-11 센터 포 프로브 디벨롭먼트 앤드 커머셜리제이션 이관능성 킬레이트 및 그의 용도의 약동학적 증진
KR102152939B1 (ko) * 2019-04-30 2020-09-07 한국화학연구원 공유결합성 트리아졸로 연결된 가시광선 흡수 광촉매, 이의 제조방법 및 이를 이용한 아자이드-알카인 고리화 첨가반응으로 트리아졸 유도체를 제조하는 방법
JP2024515104A (ja) 2021-04-20 2024-04-04 テラパワー， エルエルシー Ａｃ－２２５生成のためのチタニアに基づくジェネレータ

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989012631A1 (en) * 1988-06-24 1989-12-28 The Dow Chemical Company Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates
ZA894792B (en) * 1988-06-24 1991-04-24 Dow Chemical Co Macrocyclic bifunctional chelants,complexes thereof and their antibody conjugates
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
NZ542371A (en) * 2003-03-19 2008-10-31 Universitatsspital Basel Radiolabeled conjugates based on substance P and the uses thereof
WO2005001415A2 (en) * 2003-05-23 2005-01-06 Epix Pharmaceuticals, Inc. Optically pure and enriched isomers of chelating ligands and contrast agents
JP2008535865A (ja) * 2005-04-08 2008-09-04 サイトジェン コーポレーション 抗ｐｓｍａコンジュゲート抗体
GB0624587D0 (en) * 2006-12-08 2007-01-17 Univ Muenchen Tech Chelating agent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102898392A (zh) * 2012-09-06 2013-01-30 中国工程物理研究院核物理与化学研究所 N-乙酰氧苯基-3-[三叔丁氧甲酰基-四氮杂环十二烷基]中间体及其制备方法
CN102898392B (zh) * 2012-09-06 2015-08-12 中国工程物理研究院核物理与化学研究所 N-乙酰氧苄基-3-[-三叔丁氧甲酰基-四氮杂环十二烷基]中间体及其制备方法
CN104230832B (zh) * 2014-08-25 2018-07-27 曲靖师范学院 一种4，4’，4”，4”’-(1，4，7，10-四氮杂环十二烷-1，4，7，10-四基)四亚甲基四苯甲醛的合成方法

Also Published As

Publication number Publication date
US20100081799A1 (en) 2010-04-01
WO2008068516A1 (en) 2008-06-12
GB0624587D0 (en) 2007-01-17
EP2099776A1 (en) 2009-09-16
EP2099776B1 (en) 2015-10-07
JP5705434B2 (ja) 2015-04-22
JP2015155407A (ja) 2015-08-27
CA2671788A1 (en) 2008-06-12
JP2010511687A (ja) 2010-04-15
IN2009CN02681A (https=) 2015-08-07

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Open date: 20091216