CN101583352A - 治疗肥胖症的联苯氨基酸衍生物的制备和用途 - Google Patents

治疗肥胖症的联苯氨基酸衍生物的制备和用途 Download PDF

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Publication number
CN101583352A
CN101583352A CNA2006800350456A CN200680035045A CN101583352A CN 101583352 A CN101583352 A CN 101583352A CN A2006800350456 A CNA2006800350456 A CN A2006800350456A CN 200680035045 A CN200680035045 A CN 200680035045A CN 101583352 A CN101583352 A CN 101583352A
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amino
carbonyl
alkyl
biphenyl
alkoxy
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Chinese (zh)
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R·史密斯
D·罗维
T·谢尔克辛
G·邦达
P·夸什
S·J·奥康诺尔
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Bayer Corp
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Bayer Corp
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07C237/36—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CNA2006800350456A 2005-07-29 2006-07-31 治疗肥胖症的联苯氨基酸衍生物的制备和用途 Pending CN101583352A (zh)

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US60/703,754 2005-07-29

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US (2) US20100016295A1 (enExample)
EP (1) EP1912634A4 (enExample)
JP (1) JP2009505962A (enExample)
CN (1) CN101583352A (enExample)
CA (1) CA2617055A1 (enExample)
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CN102757420A (zh) * 2011-04-28 2012-10-31 中国科学院上海药物研究所 联杂芳基羧酸类化合物、其制备方法，包含该化合物的药物组合物、及用途
CN102781915A (zh) * 2009-12-31 2012-11-14 皮拉马尔有限公司 二酰甘油酰基转移酶抑制剂
CN103261185A (zh) * 2010-12-17 2013-08-21 田边三菱制药株式会社 连续芳环化合物
CN109475552A (zh) * 2016-08-09 2019-03-15 上海药苑生物科技有限公司 用于食欲控制和体重管理的方法和组合物

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CN103228633A (zh) 2010-09-03 2013-07-31 皮拉马尔企业有限公司 作为dgat1抑制剂的杂环化合物
FR2965262A1 (fr) 2010-09-24 2012-03-30 Sanofi Aventis Derives de nicotinamide, leur preparation et leur application en therapeutique
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EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
JP5721032B2 (ja) * 2012-06-15 2015-05-20 田辺三菱製薬株式会社 医薬組成物
WO2013187496A1 (ja) 2012-06-15 2013-12-19 田辺三菱製薬株式会社 芳香族複素環化合物
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CN102781915A (zh) * 2009-12-31 2012-11-14 皮拉马尔有限公司 二酰甘油酰基转移酶抑制剂
CN103261185A (zh) * 2010-12-17 2013-08-21 田边三菱制药株式会社 连续芳环化合物
CN103261185B (zh) * 2010-12-17 2014-12-10 田边三菱制药株式会社 连续芳环化合物
CN102757420A (zh) * 2011-04-28 2012-10-31 中国科学院上海药物研究所 联杂芳基羧酸类化合物、其制备方法，包含该化合物的药物组合物、及用途
CN102757420B (zh) * 2011-04-28 2015-02-04 中国科学院上海药物研究所 联杂芳基羧酸类化合物、其制备方法,包含该化合物的药物组合物、及用途
CN109475552A (zh) * 2016-08-09 2019-03-15 上海药苑生物科技有限公司 用于食欲控制和体重管理的方法和组合物
CN109475552B (zh) * 2016-08-09 2022-04-05 上海药苑生物科技有限公司 用于食欲控制和体重管理的方法和组合物

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