CN101484587B - Igf-ir拮抗剂作为辅药用于前列腺癌的治疗 - Google Patents

Igf-ir拮抗剂作为辅药用于前列腺癌的治疗 Download PDF

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Publication number
CN101484587B
CN101484587B CN200780012266.6A CN200780012266A CN101484587B CN 101484587 B CN101484587 B CN 101484587B CN 200780012266 A CN200780012266 A CN 200780012266A CN 101484587 B CN101484587 B CN 101484587B
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gly
igf
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val
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CN200780012266.6A
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Chinese (zh)
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CN101484587A (zh
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D·路德维希
S·R·普利梅特
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University of Washington
ImClone LLC
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University of Washington
ImClone Systems Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200780012266.6A 2006-02-03 2007-02-03 Igf-ir拮抗剂作为辅药用于前列腺癌的治疗 Expired - Fee Related CN101484587B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76507206P 2006-02-03 2006-02-03
US60/765,072 2006-02-03
PCT/US2007/003164 WO2007092453A2 (en) 2006-02-03 2007-02-03 Igf-ir antagonists as adjuvants for treatment of prostate cancer

Publications (2)

Publication Number Publication Date
CN101484587A CN101484587A (zh) 2009-07-15
CN101484587B true CN101484587B (zh) 2014-02-12

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CN200780012266.6A Expired - Fee Related CN101484587B (zh) 2006-02-03 2007-02-03 Igf-ir拮抗剂作为辅药用于前列腺癌的治疗

Country Status (17)

Country Link
US (1) US7972600B2 (OSRAM)
EP (1) EP1984011A4 (OSRAM)
JP (1) JP5198289B2 (OSRAM)
KR (1) KR101353706B1 (OSRAM)
CN (1) CN101484587B (OSRAM)
AP (1) AP2008004569A0 (OSRAM)
AU (1) AU2007212447B2 (OSRAM)
CA (1) CA2641310C (OSRAM)
CR (1) CR10188A (OSRAM)
EA (1) EA017265B1 (OSRAM)
EC (1) ECSP088706A (OSRAM)
IL (1) IL193203A0 (OSRAM)
MX (1) MX2008009977A (OSRAM)
NO (1) NO20083444L (OSRAM)
UA (1) UA95945C2 (OSRAM)
WO (1) WO2007092453A2 (OSRAM)
ZA (1) ZA200807012B (OSRAM)

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US20100214282A1 (en) 2009-02-24 2010-08-26 Dolby Laboratories Licensing Corporation Apparatus for providing light source modulation in dual modulator displays
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WO2011057064A1 (en) * 2009-11-05 2011-05-12 Brian Long Igf1r inhibitor based treatment of prostate cancer
KR101426134B1 (ko) * 2011-09-26 2014-08-06 한화케미칼 주식회사 항 ｉｇｆ-1ｒ 단일클론 항체와 ｉｌ-2를 포함하는 융합 단일클론 항체 및 이를 포함하는 암치료용 조성물
WO2013119864A1 (en) * 2012-02-07 2013-08-15 University Of Central Florida Research Foundation, Inc. Increasing taxane sensitivity in cancer cells
US10799473B2 (en) * 2013-03-04 2020-10-13 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods of inhibiting IGF-1R activation or downtream signalling thereof to reduce radiation-induced cellular senescence
US20140255413A1 (en) 2013-03-07 2014-09-11 Boehringer Ingelheim International Gmbh Combination therapy for neoplasia treatment
RU2016110546A (ru) * 2013-09-19 2017-10-24 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Комбинированная лекарственная терапия
AU2016232223A1 (en) * 2015-03-16 2017-08-31 University Of Washington Materials and methods for detecting androgen receptor splice variants and uses thereof
US20230005594A1 (en) * 2019-12-06 2023-01-05 H. Lee Moffitt Cancer Center And Research Institute, Inc. Clinical decision support for personalized adaptive prostate cancer therapy
CN113512116B (zh) 2020-04-10 2022-09-20 苏州普乐康医药科技有限公司 一种抗igf-1r抗体及其应用
EP4653017A1 (en) 2023-01-18 2025-11-26 Tyligand Bioscience (Shanghai) Limited Antibody-drug conjugate and use thereof

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Also Published As

Publication number Publication date
AP2008004569A0 (en) 2008-08-31
JP5198289B2 (ja) 2013-05-15
KR101353706B1 (ko) 2014-02-18
EP1984011A2 (en) 2008-10-29
ECSP088706A (es) 2008-10-31
KR20080090566A (ko) 2008-10-08
US7972600B2 (en) 2011-07-05
CR10188A (es) 2008-11-18
AU2007212447A1 (en) 2007-08-16
CN101484587A (zh) 2009-07-15
EP1984011A4 (en) 2010-08-18
WO2007092453A2 (en) 2007-08-16
AU2007212447B2 (en) 2013-02-21
ZA200807012B (en) 2009-12-30
EA017265B1 (ru) 2012-11-30
NO20083444L (no) 2008-10-31
WO2007092453A3 (en) 2008-12-24
UA95945C2 (ru) 2011-09-26
CA2641310A1 (en) 2007-08-16
IL193203A0 (en) 2009-08-03
JP2009525348A (ja) 2009-07-09
EA200870231A1 (ru) 2009-12-30
MX2008009977A (es) 2009-02-27
US20090175868A1 (en) 2009-07-09
CA2641310C (en) 2013-08-20

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