CN101370479A - 用于递送治疗剂的纳米团簇 - Google Patents

用于递送治疗剂的纳米团簇 Download PDF

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Publication number
CN101370479A
CN101370479A CN200680051564.1A CN200680051564A CN101370479A CN 101370479 A CN101370479 A CN 101370479A CN 200680051564 A CN200680051564 A CN 200680051564A CN 101370479 A CN101370479 A CN 101370479A
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nanocluster
nanoparticles
particle
nano
nanoclusters
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CN200680051564.1A
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Chinese (zh)
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C·J·伯克兰德
史联军
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University of Kansas
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University of Kansas
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Dermatology (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200680051564.1A 2005-12-16 2006-12-14 用于递送治疗剂的纳米团簇 Pending CN101370479A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75117205P 2005-12-16 2005-12-16
US60/751,172 2005-12-16

Publications (1)

Publication Number Publication Date
CN101370479A true CN101370479A (zh) 2009-02-18

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US (3) US7651770B2 (enExample)
EP (1) EP1968550A2 (enExample)
JP (1) JP2009519975A (enExample)
CN (1) CN101370479A (enExample)
AU (1) AU2006330627A1 (enExample)
BR (1) BRPI0619938A2 (enExample)
CA (1) CA2633380A1 (enExample)
IL (1) IL192159A0 (enExample)
MX (1) MX2008007697A (enExample)
WO (1) WO2007076295A2 (enExample)
ZA (1) ZA200805918B (enExample)

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CN103221070A (zh) * 2010-08-30 2013-07-24 哈佛大学校长及研究员协会 用于狭窄病变和溶解血栓疗法的切变控制释放
CN104550936A (zh) * 2014-12-31 2015-04-29 中国科学院合肥物质科学研究院 纳米颗粒组装的胶状体材料及其制备方法
CN105899197A (zh) * 2013-11-13 2016-08-24 蒂洛特斯制药股份有限公司 多颗粒药物递送系统
CN114901261A (zh) * 2019-04-02 2022-08-12 淅川海灵生物科技有限公司 细胞外液中激活的原子粒子的动态团簇

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Publication number Priority date Publication date Assignee Title
CN103221070A (zh) * 2010-08-30 2013-07-24 哈佛大学校长及研究员协会 用于狭窄病变和溶解血栓疗法的切变控制释放
CN103221070B (zh) * 2010-08-30 2019-07-12 哈佛大学校长及研究员协会 用于狭窄病变和溶解血栓疗法的切变控制释放
CN105899197A (zh) * 2013-11-13 2016-08-24 蒂洛特斯制药股份有限公司 多颗粒药物递送系统
CN104550936A (zh) * 2014-12-31 2015-04-29 中国科学院合肥物质科学研究院 纳米颗粒组装的胶状体材料及其制备方法
CN104550936B (zh) * 2014-12-31 2017-05-31 中国科学院合肥物质科学研究院 纳米颗粒组装的胶状体材料及其制备方法
CN114901261A (zh) * 2019-04-02 2022-08-12 淅川海灵生物科技有限公司 细胞外液中激活的原子粒子的动态团簇

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IL192159A0 (en) 2008-12-29
AU2006330627A1 (en) 2007-07-05
EP1968550A2 (en) 2008-09-17
WO2007076295A3 (en) 2007-11-29
CA2633380A1 (en) 2007-07-05
US7651770B2 (en) 2010-01-26
WO2007076295A2 (en) 2007-07-05
ZA200805918B (en) 2009-05-27
JP2009519975A (ja) 2009-05-21
US20070172653A1 (en) 2007-07-26
US20090081295A1 (en) 2009-03-26
BRPI0619938A2 (pt) 2011-10-25
MX2008007697A (es) 2008-09-26
US20090053316A1 (en) 2009-02-26

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