BRPI0619938A2 - nano agrupamentos para envio de terapêuticos - Google Patents

nano agrupamentos para envio de terapêuticos Download PDF

Info

Publication number
BRPI0619938A2
BRPI0619938A2 BRPI0619938-0A BRPI0619938A BRPI0619938A2 BR PI0619938 A2 BRPI0619938 A2 BR PI0619938A2 BR PI0619938 A BRPI0619938 A BR PI0619938A BR PI0619938 A2 BRPI0619938 A2 BR PI0619938A2
Authority
BR
Brazil
Prior art keywords
nano
nanoparticles
cluster
nanoparticle
active ingredient
Prior art date
Application number
BRPI0619938-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Cory J Berkland
Lianjun Shi
Original Assignee
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kansas filed Critical Univ Kansas
Publication of BRPI0619938A2 publication Critical patent/BRPI0619938A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Dermatology (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0619938-0A 2005-12-16 2006-12-14 nano agrupamentos para envio de terapêuticos BRPI0619938A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75117205P 2005-12-16 2005-12-16
US60/751.172 2005-12-16
PCT/US2006/062118 WO2007076295A2 (en) 2005-12-16 2006-12-14 Nanoclusters for delivery of therapeutics

Publications (1)

Publication Number Publication Date
BRPI0619938A2 true BRPI0619938A2 (pt) 2011-10-25

Family

ID=37808148

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0619938-0A BRPI0619938A2 (pt) 2005-12-16 2006-12-14 nano agrupamentos para envio de terapêuticos

Country Status (11)

Country Link
US (3) US7651770B2 (enExample)
EP (1) EP1968550A2 (enExample)
JP (1) JP2009519975A (enExample)
CN (1) CN101370479A (enExample)
AU (1) AU2006330627A1 (enExample)
BR (1) BRPI0619938A2 (enExample)
CA (1) CA2633380A1 (enExample)
IL (1) IL192159A0 (enExample)
MX (1) MX2008007697A (enExample)
WO (1) WO2007076295A2 (enExample)
ZA (1) ZA200805918B (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040096515A1 (en) * 2001-12-07 2004-05-20 Bausch Andreas R. Methods and compositions for encapsulating active agents
EP1861194A2 (en) * 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
US8906392B2 (en) * 2005-12-16 2014-12-09 University Of Kansas Nanocluster compositions and methods
US7993749B2 (en) * 2005-12-16 2011-08-09 University Of Kansas Nanoparticles comprising a nanoparticle template and a polymer shell having an amide side chain, and method of making thereof
WO2010009146A1 (en) * 2008-07-15 2010-01-21 University Of Kansas Nanoclusters for delivery of poorly water soluble drug nanoparticles
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
CN101668542B (zh) * 2007-04-27 2012-06-27 国立大学法人九州大学 肺病治疗药
DK2170283T3 (en) 2007-06-22 2019-04-15 Univ Texas CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING
US20090047318A1 (en) * 2007-08-16 2009-02-19 Abbott Cardiovascular Systems Inc. Nanoparticle-coated medical devices and formulations for treating vascular disease
US20090123509A1 (en) * 2007-11-08 2009-05-14 Cory Berkland Biodegradable Colloidal Gels as Moldable Tissue Engineering Scaffolds
US20090169639A1 (en) * 2007-12-28 2009-07-02 Boston Scientific Scimed, Inc. Particles for injection and processes for forming the same
US9182391B2 (en) * 2008-05-09 2015-11-10 Arkray, Inc. Method of producing insoluble carrier particles, insoluble carrier particles, measurement reagent, specimen analyzing tool, and immunoturbidimetric assay
CN102083419A (zh) * 2008-07-01 2011-06-01 日东电工株式会社 包含表面被覆了的微粒的医药组合物
JP5711138B2 (ja) 2008-11-16 2015-04-30 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 高濃度の低粘度懸濁液
US8053744B2 (en) * 2009-04-13 2011-11-08 Src, Inc. Location analysis using nucleic acid-labeled tags
US10952965B2 (en) * 2009-05-15 2021-03-23 Baxter International Inc. Compositions and methods for drug delivery
EP2473263B1 (en) 2009-09-02 2022-11-02 President and Fellows of Harvard College Multiple emulsions created using jetting and other techniques
US10525152B2 (en) 2009-10-09 2020-01-07 Signablok, Inc. Methods and compositions for targeted imaging
US12419839B2 (en) 2009-10-09 2025-09-23 Signablok, Inc. Methods and compositions for targeted delivery of protein fragments
KR101878749B1 (ko) * 2010-03-05 2018-07-17 삼성전자주식회사 표적 세포의 분리 방법 및 키트
KR20130016284A (ko) * 2010-03-17 2013-02-14 바스프 에스이 용융 유화
HUP1000299A2 (hu) 2010-06-08 2012-02-28 Nanoform Cardiovascular Therapeutics Ltd Nanostrukturált Atorvastatint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás elõállításukra
US8703493B2 (en) 2010-06-15 2014-04-22 Src, Inc. Location analysis using fire retardant-protected nucleic acid-labeled tags
US20120016217A1 (en) * 2010-07-15 2012-01-19 Indian Institute Of Technology Bombay Biosensor for health monitoring and uses thereof
WO2012018628A1 (en) 2010-07-26 2012-02-09 Board Of Regents, The University Of Texas System Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine
US8716027B2 (en) 2010-08-03 2014-05-06 Src, Inc. Nucleic acid-labeled tags associated with odorant
EP2611466B1 (en) * 2010-08-30 2019-06-12 President and Fellows of Harvard College Shear controlled release of thrombolytic therapies for stenotic lesions
AU2012225277A1 (en) * 2011-03-10 2013-09-26 Board Of Regents, The University Of Texas System Protein nanoparticle dispersions
WO2012162296A2 (en) 2011-05-23 2012-11-29 President And Fellows Of Harvard College Control of emulsions, including multiple emulsions
WO2012162555A2 (en) * 2011-05-24 2012-11-29 The Regents Of The University Of California Heparin nanoclusters
PH12013502474A1 (en) * 2011-06-02 2014-02-10 Consejo Superior De Investig CientaFicas C S I C Use of raman markers for authenticating security documents
WO2013006661A2 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
ES2814336T3 (es) 2012-04-13 2021-03-26 Glaxosmithkline Ip Dev Ltd Partículas de agregado
US20150147276A1 (en) * 2012-06-07 2015-05-28 President And Fellows Of Harvard College Nanotherapeutics for drug targeting
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757395B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9974850B2 (en) 2013-01-25 2018-05-22 Board Of Regents, The University Of Texas System Immunogenic compositions and uses thereof
US10149823B2 (en) 2013-04-30 2018-12-11 Otitopic Inc. Dry powder formulations and methods of use
JP6553033B2 (ja) 2013-08-13 2019-07-31 ノースウェスタン ユニバーシティ ペプチドコンジュゲート粒子
WO2015071366A1 (en) * 2013-11-13 2015-05-21 Tillotts Pharma Ag Multi-particulate drug delivery system
CN104550936B (zh) * 2014-12-31 2017-05-31 中国科学院合肥物质科学研究院 纳米颗粒组装的胶状体材料及其制备方法
JP6910029B2 (ja) * 2015-08-17 2021-07-28 国立研究開発法人科学技術振興機構 ナノクラスター分散液、ナノクラスター膜、ナノクラスター分散体、ナノクラスター分散液の製造方法およびナノクラスター分散液の製造装置
US20170128424A1 (en) * 2015-11-11 2017-05-11 Qrono, Inc. Sustained release pharmaceutical compositions and methods of use
KR101803283B1 (ko) * 2016-12-30 2017-12-01 (주)아모레퍼시픽 항노화용 또는 주름개선용 화장료 조성물
WO2019010329A1 (en) * 2017-07-06 2019-01-10 The Trustees Of The University Of Pennsylvania AGOREGATES OF INORGANIC NANOPARTICLES COATED WITH AMPHIPHILIC COLOR
US10786456B2 (en) 2017-09-22 2020-09-29 Otitopic Inc. Inhaled aspirin and magnesium to treat inflammation
CN115919780A (zh) 2017-09-22 2023-04-07 维克图拉公司 含有硬脂酸镁的干粉组合物
WO2019165240A1 (en) * 2018-02-23 2019-08-29 Rhnanopharma Nanosuspensions of salsalate and methods of using the same
WO2020201812A1 (en) * 2019-04-02 2020-10-08 Wutthinitikornkit Yanee Dynamic clusters of atom particles activated in extracellular fluid
KR20230088732A (ko) 2020-09-29 2023-06-20 옥스포드 유니버시티 이노베이션 리미티드 뇌졸중 치료

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09913A (ja) * 1995-06-14 1997-01-07 Res Dev Corp Of Japan コロイド粒子クラスターとその形成方法
US5814370A (en) * 1996-06-11 1998-09-29 Sandia Corporation Encapsulation of nanoclusters in dried gel materials via an inverse micelle/sol gel synthesis
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6656568B1 (en) * 1999-05-28 2003-12-02 The Regents Of The University Of Colorado Ordered arrays of nanoclusters
GB9929919D0 (en) * 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
US6689338B2 (en) * 2000-06-01 2004-02-10 The Board Of Regents For Oklahoma State University Bioconjugates of nanoparticles as radiopharmaceuticals
WO2002013786A2 (en) * 2000-08-15 2002-02-21 Board Of Trustees Of The University Of Illinois Method of forming microparticles
US20030138490A1 (en) * 2001-09-08 2003-07-24 Zhibing Hu Synthesis and uses of polymer gel nanoparticle networks
WO2003062372A2 (en) 2001-10-02 2003-07-31 The Regents Of The University Of California Nanoparticle assembled hollow spheres
US20030062372A1 (en) * 2001-10-02 2003-04-03 Metso Minerals (Trelleborg) Ab Wear-resistant lining element and wear lining made thereof
US6562403B2 (en) * 2001-10-15 2003-05-13 Kansas State University Research Foundation Synthesis of substantially monodispersed colloids
WO2003065394A2 (en) * 2002-01-25 2003-08-07 Konarka Technologies, Inc. Photovoltaic cell components and materials
EP1480691A4 (en) * 2002-03-05 2007-11-28 Univ State Cleveland AGGLOMERATED PARTICLES FOR THE DISPOSAL OF A MEDICINAL PRODUCT IN AEROSOL FORM
AU2003265229A1 (en) 2002-03-18 2003-12-12 Sciperio, Inc. Dentritic cell nodes
JP4142318B2 (ja) * 2002-03-20 2008-09-03 株式会社ホソカワ粉体技術研究所 薬物含有複合粒子の製造方法
JP4448441B2 (ja) * 2002-06-05 2010-04-07 ユニヴァーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド 眼科用医薬のデリバリーシステム
EP1543841A4 (en) * 2002-08-15 2011-03-16 Yunqing Liu SOLID PHARMACEUTICAL NANO FORMULATION AND MANUFACTURING METHOD THEREFOR
US7811605B2 (en) * 2002-11-06 2010-10-12 Uluru Inc. Method of formation of shape-retentive aggregates of gel particles and their uses
US6928201B2 (en) * 2002-11-15 2005-08-09 Sunrise Telecom Incorporated Method and apparatus for providing controllable second-order polarization mode dispersion
KR20060015534A (ko) * 2003-04-25 2006-02-17 더 펜 스테이트 리서치 파운데이션 성장 억제, 지질 유래된 생활성 화합물의 전신 전달을 위한방법 및 시스템
JP2007528848A (ja) * 2003-07-09 2007-10-18 ヴァックスデザイン・コーポレーション ワクチン接種ノードを用いるプログラムされた免疫応答
CA2435632A1 (en) * 2003-07-21 2005-01-21 Warren Hugh Finlay Formulation of powder containing nanoparticles for aerosol delivery to the lung
AU2004298723B2 (en) * 2003-12-19 2008-07-10 Scf Technologies A/S Systems for preparing fine particles and other substances
CN1897978B (zh) * 2003-12-22 2011-11-23 博莱科瑞士股份有限公司 具有用于反差成像的活性组分的充气微囊组件
US7610074B2 (en) * 2004-01-08 2009-10-27 The Board Of Trustees Of The University Of Illinois Multi-functional plasmon-resonant contrast agents for optical coherence tomography

Also Published As

Publication number Publication date
CN101370479A (zh) 2009-02-18
IL192159A0 (en) 2008-12-29
AU2006330627A1 (en) 2007-07-05
EP1968550A2 (en) 2008-09-17
WO2007076295A3 (en) 2007-11-29
CA2633380A1 (en) 2007-07-05
US7651770B2 (en) 2010-01-26
WO2007076295A2 (en) 2007-07-05
ZA200805918B (en) 2009-05-27
JP2009519975A (ja) 2009-05-21
US20070172653A1 (en) 2007-07-26
US20090081295A1 (en) 2009-03-26
MX2008007697A (es) 2008-09-26
US20090053316A1 (en) 2009-02-26

Similar Documents

Publication Publication Date Title
US7651770B2 (en) Nanoclusters for delivery of therapeutics
US9278069B2 (en) Nanoclusters compositions and methods
Pardeshi et al. Solid lipid based nanocarriers: An overview/Nanonosaci na bazi cvrstih lipida: Pregled
JP6590750B2 (ja) 粘膜浸透が増強されたかまたは炎症が低減されたナノ粒子
US8853260B2 (en) Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
WO2010009146A1 (en) Nanoclusters for delivery of poorly water soluble drug nanoparticles
US8137684B2 (en) Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
EP1023050B1 (en) Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US20070117863A1 (en) Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US8501232B2 (en) Process of forming and modifying particles and compositions produced thereby
Bohr et al. Nanoembedded microparticles for stabilization and delivery of drug-loaded nanoparticles
US20050181059A1 (en) Nanoparticulate therapeutic biologically active agents
US20050019270A1 (en) Formulation of powder containing nanoparticles for aerosol delivery to the lungs
Elsayed et al. Inhalable nanocomposite microparticles: preparation, characterization and factors affecting formulation
EP3266450A1 (en) Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
Kunda et al. Polymer‐based Delivery Systems for the Pulmonary Delivery of Biopharmaceuticals
PARDESHI et al. Nanonosači na bazi čvrstih lipida: Pregled
Jadhav et al. Brief Study of Nanocarrier Drug Delivery System
Singh PREPARATION, CHARACTERIZATION AND PHARMACODYNAMIC STUDIES OF CEFOVECIN NANOPARTICLES
HK1030543B (en) Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
HK1152882A (en) Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/51 (2006.01), A61K 9/00 (2006.01), A61K 9/1