CN101175862A - 诊断膀胱癌的方法 - Google Patents
诊断膀胱癌的方法 Download PDFInfo
- Publication number
- CN101175862A CN101175862A CNA2006800115808A CN200680011580A CN101175862A CN 101175862 A CN101175862 A CN 101175862A CN A2006800115808 A CNA2006800115808 A CN A2006800115808A CN 200680011580 A CN200680011580 A CN 200680011580A CN 101175862 A CN101175862 A CN 101175862A
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- Prior art keywords
- polypeptide
- seq
- bladder cancer
- gene
- blc
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65231805P | 2005-02-10 | 2005-02-10 | |
| US60/652,318 | 2005-02-10 | ||
| US70322505P | 2005-07-27 | 2005-07-27 | |
| US60/703,225 | 2005-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101175862A true CN101175862A (zh) | 2008-05-07 |
Family
ID=36570700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006800115808A Pending CN101175862A (zh) | 2005-02-10 | 2006-02-09 | 诊断膀胱癌的方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US7998695B2 (enExample) |
| EP (5) | EP2011885B1 (enExample) |
| JP (2) | JP5109131B2 (enExample) |
| CN (1) | CN101175862A (enExample) |
| WO (1) | WO2006085684A2 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102858999A (zh) * | 2009-12-01 | 2013-01-02 | 简要生物科学有限公司 | 癌症的分类 |
| CN103033625A (zh) * | 2012-12-19 | 2013-04-10 | 中国科学院生物物理研究所 | 一种人膀胱癌细胞化学发光检测试剂盒及其制备方法 |
| CN107400704A (zh) * | 2016-05-20 | 2017-11-28 | 博尔诚(北京)科技有限公司 | 一种用于乳腺癌筛查的组合物及其应用 |
| CN110320369A (zh) * | 2019-07-31 | 2019-10-11 | 天津医科大学第二医院 | 一种诊断膀胱癌试剂盒 |
| CN111206093A (zh) * | 2018-11-21 | 2020-05-29 | 立森印迹诊断技术(无锡)有限公司 | 一种用于检测浸润性膀胱癌的标志物及其应用 |
| CN114854860A (zh) * | 2022-05-05 | 2022-08-05 | 北京化工大学 | 一种膀胱癌干细胞生物标志物组及其应用 |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1668354A2 (en) | 2003-09-24 | 2006-06-14 | Oncotherapy Science, Inc. | Method of diagnosing breast cancer |
| CA2862993C (en) * | 2004-07-23 | 2019-01-15 | Pacific Edge Biotechnology Ltd. | Urine markers for detection of bladder cancer |
| EP1851543A2 (en) | 2005-02-24 | 2007-11-07 | Compugen Ltd. | Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof |
| AU2006241235B2 (en) * | 2005-04-22 | 2012-04-05 | Eisai, Inc. | Antibodies with immune effector activity and that internalize in endosialin-positive cells |
| TW200741009A (en) * | 2005-07-01 | 2007-11-01 | Oncotherapy Science Inc | Methods of modulating SMYD3 for treatment of cancer |
| CN101432303A (zh) * | 2006-02-28 | 2009-05-13 | 肿瘤疗法科学股份有限公司 | 利用抗cdh3抗体的效应物功能来损伤细胞的方法 |
| US8673548B2 (en) | 2006-08-10 | 2014-03-18 | Oncotherapy Science, Inc. | Genes and polypeptides relating to breast cancers |
| CA2661662A1 (en) * | 2006-08-25 | 2008-02-28 | Oncotherapy Science, Inc. | Methods of screening for agents that inhibit binding between mphosph1 and prc1 |
| KR101454287B1 (ko) * | 2006-10-17 | 2014-11-04 | 온코세라피 사이언스 가부시키가이샤 | Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신 |
| AU2013200566B2 (en) * | 2006-10-17 | 2014-10-09 | Oncotherapy Science, Inc. | Peptide vaccines for cancers expressing MPHOSPH1 or DEPDC1 polypeptides |
| US20100009920A1 (en) * | 2006-12-13 | 2010-01-14 | Yusuke Nakamura | Ttk as tumor marker and therapeutic target for lung cancer |
| RS53362B (sr) | 2007-04-05 | 2014-10-31 | Morphotek, Inc. | Postupak inhibiranja vezivanja endosijalina na ligande |
| WO2008152816A1 (en) | 2007-06-14 | 2008-12-18 | Oncotherapy Science, Inc. | Methods of identifying agents that modulate methylation of vegfr1 by smyd3 |
| TW200908998A (en) * | 2007-06-27 | 2009-03-01 | Oncotherapy Science Inc | Compositions and methods of treating cancer |
| WO2009016691A1 (en) * | 2007-07-30 | 2009-02-05 | Oncotherapy Science, Inc. | Cancer associated gene ly6k |
| SG183717A1 (en) | 2007-08-20 | 2012-09-27 | Oncotherapy Science Inc | Foxm1 peptide and medicinal agent comprising the same |
| UA100127C2 (ru) | 2007-08-20 | 2012-11-26 | Онкотерапи Саенс, Инк. | Пептид cdh3 и лекарственное средство, содержащее его |
| AU2008290061B2 (en) * | 2007-08-20 | 2014-01-30 | Oncotherapy Science, Inc. | CDCA1 peptide and pharmaceutical agent comprising the same |
| WO2009028580A1 (en) * | 2007-08-24 | 2009-03-05 | Oncotherapy Science, Inc. | Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer therapy and diagnosis |
| US20120135875A1 (en) * | 2008-02-29 | 2012-05-31 | Bristol-Myers Squibb Company | Methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
| WO2009113674A1 (ja) * | 2008-03-14 | 2009-09-17 | 学校法人北里研究所 | 膀胱癌の診断 |
| US8652478B2 (en) | 2008-06-09 | 2014-02-18 | Oxford Biotherapeutics Ltd. | Method for treating cancer by administering antibody to ephrin type-A receptor 7 |
| TW201000119A (en) * | 2008-06-10 | 2010-01-01 | Oncotherapy Science Inc | MYBL2 epitope peptides and vaccines containing the same |
| TW201000115A (en) * | 2008-06-11 | 2010-01-01 | Oncotherapy Science Inc | IQGAP3 epitope peptides and vaccines containing the same |
| TWI526219B (zh) | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Cdca1抗原決定位胜肽及含此胜肽的疫苗 |
| CA2729403A1 (en) | 2008-06-30 | 2010-01-07 | Oncotherapy Science, Inc. | Anti-cdh3 antibodies labeled with radioisotope label and uses thereof |
| TWI466680B (zh) | 2008-08-01 | 2015-01-01 | Oncotherapy Science Inc | Melk抗原決定位胜肽及含此胜肽的疫苗 |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| TWI543767B (zh) | 2008-08-19 | 2016-08-01 | 腫瘤療法 科學股份有限公司 | Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 |
| CA2735148A1 (en) * | 2008-08-28 | 2010-03-04 | Oncotherapy Science, Inc. | Oip5 as a target gene for cancer therapy and diagnosis |
| EP2362904B1 (en) * | 2008-08-28 | 2016-11-16 | Oncotherapy Science, Inc. | Method of screening compounds for use in inhibiting depdc1 - znf224 binding |
| JP5663790B2 (ja) | 2008-10-22 | 2015-02-04 | オンコセラピー・サイエンス株式会社 | Rab6kifl/kif20aエピトープペプチドおよびそれを含むワクチン |
| US20110301056A1 (en) * | 2008-12-12 | 2011-12-08 | Oncotherapy Science, Inc. | Nectin-4 for target genes of cancer therapy and diagnosis |
| GB0823445D0 (en) * | 2008-12-23 | 2009-01-28 | Univ Surrey | Biomarker |
| CA2751161C (en) | 2008-12-30 | 2018-10-02 | Children's Medical Center Corporation | Method of predicting acute appendicitis |
| TWI469791B (zh) | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Foxm1胜肽以及含此胜肽之疫苗 |
| TW201102081A (en) | 2009-05-11 | 2011-01-16 | Oncotherapy Science Inc | TTK peptides and vaccines including the same |
| CN102549169B (zh) * | 2009-07-24 | 2016-02-24 | 吉第克生物技术有限公司 | 子宫内膜癌的标记物 |
| US20120231472A1 (en) * | 2009-11-07 | 2012-09-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011069014A1 (en) | 2009-12-04 | 2011-06-09 | Cedars-Sinai Medical Center | Tox3 as a biomarker for breast cancer |
| GB0922085D0 (en) * | 2009-12-17 | 2010-02-03 | Cambridge Entpr Ltd | Cancer diagnosis and treatment |
| ES2701626T3 (es) | 2009-12-28 | 2019-02-25 | Oncotherapy Science Inc | Anticuerpos anti-CDH3 y sus usos |
| TWI485245B (zh) | 2010-01-25 | 2015-05-21 | Oncotherapy Science Inc | 經修飾之melk胜肽及含此胜肽之疫苗 |
| TWI538685B (zh) | 2010-04-02 | 2016-06-21 | 腫瘤療法 科學股份有限公司 | Ect2胜肽及含此胜肽之疫苗 |
| EP2380991A1 (en) | 2010-04-20 | 2011-10-26 | Universitätsklinikum Hamburg-Eppendorf | Method of determining the metastatic potential of a tumor |
| US20110262921A1 (en) * | 2010-04-23 | 2011-10-27 | Sabichi Anita L | Test for the Detection of Bladder Cancer |
| WO2012009382A2 (en) * | 2010-07-12 | 2012-01-19 | The Regents Of The University Of Colorado | Molecular indicators of bladder cancer prognosis and prediction of treatment response |
| CN103153063B (zh) | 2010-07-30 | 2016-02-17 | 肿瘤疗法科学股份有限公司 | 喹啉衍生物及含有其的melk抑制剂 |
| EP2426216A1 (en) * | 2010-09-01 | 2012-03-07 | Institut Gustave Roussy (IGR) | Prognostic and/or predictive biomarkers and biological applications thereof |
| EP2670866A4 (en) * | 2011-04-05 | 2015-09-02 | Translational Genomics Res Inst | BIOMARKERS AND METHOD OF APPLICATION THEREFOR |
| WO2012178087A1 (en) * | 2011-06-22 | 2012-12-27 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of bladder cancer |
| WO2013018690A1 (ja) | 2011-07-29 | 2013-02-07 | 国立大学法人徳島大学 | Erap1由来ペプチド及びその使用 |
| DK2742133T3 (en) | 2011-08-12 | 2017-12-04 | Oncotherapy Science Inc | MPHOSPH1 PEPTIDES AND VACCINES CONTAINING THESE |
| SG10201608552WA (en) | 2011-10-28 | 2016-12-29 | Oncotherapy Science Inc | Topk Peptides And Vaccines Including The Same |
| EP2776832A4 (en) * | 2011-11-11 | 2015-06-03 | Metabolon Inc | BIOMARKER FOR BUBBLE CANCER AND METHOD FOR ITS USE |
| HUE045359T2 (hu) | 2011-12-14 | 2019-12-30 | Univ Texas | Kollaterális gén inaktiváló biomarkerek és célsejtek a rákterápiában |
| SG11201403335WA (en) | 2012-01-19 | 2014-09-26 | Oncotherapy Science Inc | 1,5-naphthyridine derivatives and melk inhibitors containing the same |
| WO2013134649A1 (en) * | 2012-03-09 | 2013-09-12 | Verastem, Inc. | Biomarkers for cancer stem cells and related methods of use |
| EP2872531A4 (en) | 2012-07-10 | 2016-04-06 | Oncotherapy Science Inc | LY6K EPITOPE PEPTIDES FOR TH1 CELLS AND VACCINES CONTAINING SAME |
| JP6259983B2 (ja) | 2012-07-10 | 2018-01-17 | オンコセラピー・サイエンス株式会社 | Th1細胞のKIF20Aエピトープペプチドおよびこれを含有するワクチン |
| JP6255593B2 (ja) | 2012-07-10 | 2018-01-10 | オンコセラピー・サイエンス株式会社 | Th1細胞のCDCA1エピトープペプチドおよびこれを含有するワクチン |
| KR101942148B1 (ko) | 2012-09-27 | 2019-01-24 | 추가이 세이야쿠 가부시키가이샤 | Fgfr3 융합 유전자 및 그것을 표적으로 하는 의약 |
| DE102012021222B4 (de) * | 2012-10-27 | 2015-02-05 | Forschungszentrum Jülich GmbH | Verfahren zur Herstellung einer nanoporösen Schicht auf einem Substrat |
| WO2014138396A1 (en) * | 2013-03-06 | 2014-09-12 | Cepheid | Methods of detecting bladder cancer |
| EP3696283B1 (en) * | 2013-03-08 | 2022-02-16 | MDxHealth Research B.V. | Molecular markers in bladder cancer |
| TWI658049B (zh) | 2013-03-12 | 2019-05-01 | 腫瘤療法 科學股份有限公司 | Kntc2胜肽及含此胜肽之疫苗 |
| KR101573467B1 (ko) * | 2013-04-10 | 2015-12-01 | (주)지노믹트리 | 방광암 특이적 후성유전적 마커 유전자를 이용한 방광암의 검출방법 |
| CA2928901A1 (en) * | 2013-11-04 | 2015-05-07 | The University Of British Columbia | Cancer biomarkers and classifiers and uses thereof |
| SG11201609707WA (en) | 2014-07-01 | 2017-01-27 | Pfizer | Bispecific heterodimeric diabodies and uses thereof |
| CN107074908B (zh) | 2014-08-04 | 2021-10-15 | 肿瘤疗法科学股份有限公司 | Cdca1衍生的肽和含有它们的疫苗 |
| SG11201700838VA (en) | 2014-08-04 | 2017-03-30 | Oncotherapy Science Inc | Urlc10-derived peptide and vaccine containing same |
| WO2016115089A1 (en) | 2015-01-12 | 2016-07-21 | The George Washington University a Congressionally Chartered Not-for-Profit Corporation | Blood biomarkers for respiratory infections |
| WO2016154493A1 (en) * | 2015-03-24 | 2016-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for multi-scale, annotation-independent detection of functionally-diverse units of recurrent genomic alteration |
| GB201511191D0 (en) * | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
| CN112961213A (zh) | 2015-08-12 | 2021-06-15 | 肿瘤疗法科学股份有限公司 | Depdc1衍生的肽和包含它们的疫苗 |
| CA3000808A1 (en) | 2015-10-08 | 2017-04-13 | Sachiko YAMASHITA | Mphosph1-derived peptide, and vaccine including same |
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| JP6769596B2 (ja) * | 2016-05-30 | 2020-10-14 | 学校法人北里研究所 | 膀胱癌診断薬及び生体試料の判定方法 |
| RU2756982C2 (ru) | 2016-08-31 | 2021-10-07 | Онкотерапи Сайенс, Инк. | Моноклональное антитело против melk и его использование |
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| NL2020004B1 (en) | 2016-12-09 | 2018-07-02 | Ary Flohil Jacob | Treatment of diffuse intrinsic pontine glioma |
| WO2019017384A1 (ja) | 2017-07-19 | 2019-01-24 | 国立大学法人徳島大学 | ペプチド誘導体及びそれを含む医薬組成物 |
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| TW202023581A (zh) | 2018-08-02 | 2020-07-01 | 日商腫瘤療法 科學股份有限公司 | 來自cdca1的胜肽及含有此的疫苗 |
| US20210379148A1 (en) * | 2020-05-12 | 2021-12-09 | University Of Maryland, Baltimore | Regulating muscle physiology and energy metabolism using crym |
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| WO2024192018A1 (en) * | 2023-03-12 | 2024-09-19 | Novelna Inc. | Bladder cancer detection proteins and methods of use thereof |
| CN120064671B (zh) * | 2025-04-29 | 2025-07-29 | 吉林大学 | 用于检测幼儿唾液prb1含量的组合物及应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0239102A3 (en) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| JP2938569B2 (ja) | 1990-08-29 | 1999-08-23 | ジェンファーム インターナショナル,インコーポレイティド | 異種免疫グロブリンを作る方法及びトランスジェニックマウス |
| SG48760A1 (en) | 1992-07-24 | 2003-03-18 | Abgenix Inc | Generation of xenogenetic antibodies |
| CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69637481T2 (de) | 1995-04-27 | 2009-04-09 | Amgen Fremont Inc. | Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8 |
| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| US7001999B1 (en) * | 1998-04-15 | 2006-02-21 | Ludwig Institute For Cancer Research | Tumor associated nucleic acids and uses therefor |
| US20020103360A1 (en) | 1998-09-01 | 2002-08-01 | Yang Pan | Novel protein related to melanoma-inhibiting protein and uses thereof |
| US20040241726A1 (en) * | 1999-01-06 | 2004-12-02 | Chondrogene Limited | Method for the detection of allergies related gene transcripts in blood |
| US20050123938A1 (en) * | 1999-01-06 | 2005-06-09 | Chondrogene Limited | Method for the detection of osteoarthritis related gene transcripts in blood |
| IL148798A0 (en) | 1999-09-27 | 2002-09-12 | Quark Biotech Inc | Sequences characteristic of bladder cancer |
| WO2001053312A1 (en) | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| AU2001231025A1 (en) * | 2000-01-20 | 2001-07-31 | Cedars-Sinai Medical Center | Method of detecting neoplastic, hyperplastic, cytologically dysplastic and/or premalignant cellular growth or proliferation |
| CA2425827A1 (en) | 2000-10-12 | 2002-04-18 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| US20030157561A1 (en) | 2001-11-19 | 2003-08-21 | Kolkman Joost A. | Combinatorial libraries of monomer domains |
| US20040076955A1 (en) * | 2001-07-03 | 2004-04-22 | Eos Biotechnology, Inc. | Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer |
| US7494646B2 (en) * | 2001-09-06 | 2009-02-24 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| US20040142325A1 (en) * | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| WO2003083074A2 (en) * | 2002-03-28 | 2003-10-09 | Idec Pharmaceuticals Corporation | Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas |
| TW200413725A (en) * | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
| DE602004032114D1 (de) | 2003-02-28 | 2011-05-19 | Oncotherapy Science Inc | Rna-interferenz für das gen znfn3a1 als verfahren zur hemmung des wachstums von krebszellen |
| EP2343384A3 (en) | 2004-03-23 | 2012-01-04 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancer |
| KR101454287B1 (ko) | 2006-10-17 | 2014-11-04 | 온코세라피 사이언스 가부시키가이샤 | Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신 |
| WO2008152816A1 (en) * | 2007-06-14 | 2008-12-18 | Oncotherapy Science, Inc. | Methods of identifying agents that modulate methylation of vegfr1 by smyd3 |
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- 2011-11-24 JP JP2011256511A patent/JP2012135301A/ja not_active Ceased
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102858999A (zh) * | 2009-12-01 | 2013-01-02 | 简要生物科学有限公司 | 癌症的分类 |
| CN103033625A (zh) * | 2012-12-19 | 2013-04-10 | 中国科学院生物物理研究所 | 一种人膀胱癌细胞化学发光检测试剂盒及其制备方法 |
| CN103033625B (zh) * | 2012-12-19 | 2014-12-24 | 中国科学院生物物理研究所 | 一种人膀胱癌细胞化学发光检测试剂盒及其制备方法 |
| CN107400704A (zh) * | 2016-05-20 | 2017-11-28 | 博尔诚(北京)科技有限公司 | 一种用于乳腺癌筛查的组合物及其应用 |
| CN111206093A (zh) * | 2018-11-21 | 2020-05-29 | 立森印迹诊断技术(无锡)有限公司 | 一种用于检测浸润性膀胱癌的标志物及其应用 |
| CN110320369A (zh) * | 2019-07-31 | 2019-10-11 | 天津医科大学第二医院 | 一种诊断膀胱癌试剂盒 |
| CN110320369B (zh) * | 2019-07-31 | 2022-05-17 | 天津医科大学第二医院 | 一种诊断膀胱癌试剂盒 |
| CN114854860A (zh) * | 2022-05-05 | 2022-08-05 | 北京化工大学 | 一种膀胱癌干细胞生物标志物组及其应用 |
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| JP2012135301A (ja) | 2012-07-19 |
| US20120014996A1 (en) | 2012-01-19 |
| WO2006085684A2 (en) | 2006-08-17 |
| EP1856278A2 (en) | 2007-11-21 |
| EP2011885A3 (en) | 2009-06-24 |
| US8685641B2 (en) | 2014-04-01 |
| US20090175844A1 (en) | 2009-07-09 |
| EP2011885B1 (en) | 2015-04-22 |
| EP2011885A2 (en) | 2009-01-07 |
| US7998695B2 (en) | 2011-08-16 |
| EP2292796A1 (en) | 2011-03-09 |
| US20130011933A1 (en) | 2013-01-10 |
| JP2008532477A (ja) | 2008-08-21 |
| EP2311983A1 (en) | 2011-04-20 |
| JP5109131B2 (ja) | 2012-12-26 |
| EP2295601A1 (en) | 2011-03-16 |
| WO2006085684A3 (en) | 2007-03-29 |
| WO2006085684A9 (en) | 2006-10-19 |
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