CN101160401A - 免疫刺激寡核苷酸 - Google Patents

免疫刺激寡核苷酸 Download PDF

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Publication number
CN101160401A
CN101160401A CNA2006800128117A CN200680012811A CN101160401A CN 101160401 A CN101160401 A CN 101160401A CN A2006800128117 A CNA2006800128117 A CN A2006800128117A CN 200680012811 A CN200680012811 A CN 200680012811A CN 101160401 A CN101160401 A CN 101160401A
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China
Prior art keywords
oligonucleotide
seq
guanine
nucleotide
nucleotides
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Pending
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CNA2006800128117A
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English (en)
Chinese (zh)
Inventor
A·M·克里格
U·萨姆洛维茨
J·沃尔默
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Coley Pharmaceutical GmbH
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Coley Pharmaceutical GmbH
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/04—Antibacterial agents
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
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    • C12N2310/3125—Methylphosphonates
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    • C12N2310/30—Chemical structure
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/35—Nature of the modification
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  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2006800128117A 2005-02-24 2006-02-24 免疫刺激寡核苷酸 Pending CN101160401A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65593105P 2005-02-24 2005-02-24
US60/655,931 2005-02-24

Publications (1)

Publication Number Publication Date
CN101160401A true CN101160401A (zh) 2008-04-09

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US (1) US20080009455A9 (enExample)
EP (1) EP1851314A2 (enExample)
JP (1) JP2008531018A (enExample)
CN (1) CN101160401A (enExample)
AU (1) AU2006216493A1 (enExample)
CA (1) CA2598992A1 (enExample)
WO (1) WO2006091915A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111447949A (zh) * 2017-12-15 2020-07-24 拜耳动物保健有限责任公司 免疫刺激寡核苷酸

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