CN101050216A - 一种抗乙肝药物恩替卡韦的合成方法 - Google Patents
一种抗乙肝药物恩替卡韦的合成方法 Download PDFInfo
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- CN101050216A CN101050216A CNA2006100393133A CN200610039313A CN101050216A CN 101050216 A CN101050216 A CN 101050216A CN A2006100393133 A CNA2006100393133 A CN A2006100393133A CN 200610039313 A CN200610039313 A CN 200610039313A CN 101050216 A CN101050216 A CN 101050216A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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CN2006100393133A CN101050216B (zh) | 2006-04-05 | 2006-04-05 | 一种抗乙肝药物恩替卡韦的合成方法 |
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CN101050216A true CN101050216A (zh) | 2007-10-10 |
CN101050216B CN101050216B (zh) | 2011-01-12 |
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Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101906113A (zh) * | 2010-07-06 | 2010-12-08 | 苏州汉德森医药科技有限公司 | 抗病毒药恩替卡韦中间体的制备方法 |
CN101693713B (zh) * | 2009-10-28 | 2011-11-09 | 福建广生堂药业有限公司 | 一种恩替卡韦的晶型及其制备方法和药物应用 |
CN101531660B (zh) * | 2009-04-14 | 2012-07-04 | 安徽贝克联合制药有限公司 | 一种恩替卡韦一水合物的工业化生产工艺 |
EP2484685A1 (en) * | 2009-09-30 | 2012-08-08 | Sumitomo Chemical Co., Ltd | Transition metal complex, preparation method for said transition metal complex, trimerization catalyst, preparation method for 1-hexene, preparation method for ethylene polymer, substituted cyclopentadiene compound, and preparation method for said substituted cyclopentadiene compound |
CN102952156A (zh) * | 2011-08-29 | 2013-03-06 | 南京工业大学 | 一种抗乙肝药物恩替卡韦中间体及其合成 |
CN102952135A (zh) * | 2011-08-31 | 2013-03-06 | 南京工业大学 | 一种乙肝药物恩替卡韦的合成方法 |
CN102952136A (zh) * | 2012-11-11 | 2013-03-06 | 苏州二叶制药有限公司 | 恩替卡韦及其制备方法 |
CN104017013A (zh) * | 2013-02-28 | 2014-09-03 | 浙江星月药物科技股份有限公司 | 一类恩替卡韦的中间体的制备方法,以及中间体 |
WO2014187188A1 (zh) * | 2013-05-23 | 2014-11-27 | 浙江星月药物科技股份有限公司 | 恩替卡韦的制备方法、中间体及其制备方法 |
CN104177396A (zh) * | 2013-05-23 | 2014-12-03 | 浙江星月药物科技股份有限公司 | 恩替卡韦中间体及其制备方法 |
US8937195B2 (en) | 2011-03-29 | 2015-01-20 | Sumitomo Chemical Company, Limited | Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) |
US9090527B2 (en) | 2011-03-29 | 2015-07-28 | Sumitomo Chemical Company, Limited | Method for producing transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing substituted cyclopentadiene compound (2) |
CN105837573A (zh) * | 2016-03-28 | 2016-08-10 | 江西青峰药业有限公司 | 一种9-[(3aS,4S,6S,6aR)-3a,6-二羟基六氢-1H-环戊二烯并[c]呋喃-4-基]鸟嘌呤的制备方法 |
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2006
- 2006-04-05 CN CN2006100393133A patent/CN101050216B/zh active Active
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101531660B (zh) * | 2009-04-14 | 2012-07-04 | 安徽贝克联合制药有限公司 | 一种恩替卡韦一水合物的工业化生产工艺 |
EP2484685A1 (en) * | 2009-09-30 | 2012-08-08 | Sumitomo Chemical Co., Ltd | Transition metal complex, preparation method for said transition metal complex, trimerization catalyst, preparation method for 1-hexene, preparation method for ethylene polymer, substituted cyclopentadiene compound, and preparation method for said substituted cyclopentadiene compound |
US9919300B2 (en) | 2009-09-30 | 2018-03-20 | Sumitomo Chemical Company, Limited | 1-hexene production process |
EP2484685A4 (en) * | 2009-09-30 | 2013-11-13 | Sumitomo Chemical Co | TRANSITION METAL COMPLEX, METHOD OF MANUFACTURING THIS TRANSITION METAL COMPLEX, TRIMERIZING CATALYST, PRODUCTION PROCESS FOR 1-HEXES, PRODUCTION METHOD FOR AN ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIA COMPOUND, AND METHOD OF MANUFACTURING THIS SUBSTITUTED CYCLOPENTADIATE COMPOUND |
CN101693713B (zh) * | 2009-10-28 | 2011-11-09 | 福建广生堂药业有限公司 | 一种恩替卡韦的晶型及其制备方法和药物应用 |
CN101906113A (zh) * | 2010-07-06 | 2010-12-08 | 苏州汉德森医药科技有限公司 | 抗病毒药恩替卡韦中间体的制备方法 |
US8937195B2 (en) | 2011-03-29 | 2015-01-20 | Sumitomo Chemical Company, Limited | Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) |
US9090527B2 (en) | 2011-03-29 | 2015-07-28 | Sumitomo Chemical Company, Limited | Method for producing transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing substituted cyclopentadiene compound (2) |
CN102952156A (zh) * | 2011-08-29 | 2013-03-06 | 南京工业大学 | 一种抗乙肝药物恩替卡韦中间体及其合成 |
CN102952135B (zh) * | 2011-08-31 | 2015-04-08 | 南京工业大学 | 一种乙肝药物恩替卡韦的合成方法 |
CN102952135A (zh) * | 2011-08-31 | 2013-03-06 | 南京工业大学 | 一种乙肝药物恩替卡韦的合成方法 |
CN102952136A (zh) * | 2012-11-11 | 2013-03-06 | 苏州二叶制药有限公司 | 恩替卡韦及其制备方法 |
CN104017013A (zh) * | 2013-02-28 | 2014-09-03 | 浙江星月药物科技股份有限公司 | 一类恩替卡韦的中间体的制备方法,以及中间体 |
CN104177396A (zh) * | 2013-05-23 | 2014-12-03 | 浙江星月药物科技股份有限公司 | 恩替卡韦中间体及其制备方法 |
WO2014187188A1 (zh) * | 2013-05-23 | 2014-11-27 | 浙江星月药物科技股份有限公司 | 恩替卡韦的制备方法、中间体及其制备方法 |
CN105837573A (zh) * | 2016-03-28 | 2016-08-10 | 江西青峰药业有限公司 | 一种9-[(3aS,4S,6S,6aR)-3a,6-二羟基六氢-1H-环戊二烯并[c]呋喃-4-基]鸟嘌呤的制备方法 |
CN105837573B (zh) * | 2016-03-28 | 2018-07-27 | 江西青峰药业有限公司 | 一种9-[3a,6-二羟基六氢-1H-环戊二烯并[c]呋喃-4-基]鸟嘌呤的制备方法 |
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CN101050216B (zh) | 2011-01-12 |
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