CN101020043A - 小建中胶囊的防潮包衣方法 - Google Patents
小建中胶囊的防潮包衣方法 Download PDFInfo
- Publication number
- CN101020043A CN101020043A CN 200710077673 CN200710077673A CN101020043A CN 101020043 A CN101020043 A CN 101020043A CN 200710077673 CN200710077673 CN 200710077673 CN 200710077673 A CN200710077673 A CN 200710077673A CN 101020043 A CN101020043 A CN 101020043A
- Authority
- CN
- China
- Prior art keywords
- coating
- hours
- clear paste
- capsule
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000576 coating method Methods 0.000 title claims abstract description 51
- 239000002775 capsule Substances 0.000 title claims abstract description 17
- 239000011248 coating agent Substances 0.000 claims abstract description 41
- 239000000843 powder Substances 0.000 claims abstract description 27
- 239000000463 material Substances 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 14
- 238000002360 preparation method Methods 0.000 claims abstract description 9
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims abstract description 5
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 23
- 239000008187 granular material Substances 0.000 claims description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 239000007921 spray Substances 0.000 claims description 10
- 239000000341 volatile oil Substances 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 9
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 9
- 239000006071 cream Substances 0.000 claims description 7
- 239000000243 solution Substances 0.000 claims description 7
- 238000001291 vacuum drying Methods 0.000 claims description 6
- 238000004821 distillation Methods 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 239000002245 particle Substances 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 5
- -1 hydroxypropyl Chemical group 0.000 claims description 4
- 238000012545 processing Methods 0.000 claims description 3
- 238000005469 granulation Methods 0.000 claims description 2
- 230000003179 granulation Effects 0.000 claims description 2
- 238000007796 conventional method Methods 0.000 claims 2
- 239000008188 pellet Substances 0.000 abstract 3
- 238000005453 pelletization Methods 0.000 abstract 2
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 7
- 238000010521 absorption reaction Methods 0.000 description 6
- 229940079593 drug Drugs 0.000 description 5
- 238000011049 filling Methods 0.000 description 5
- 239000002994 raw material Substances 0.000 description 4
- 239000002671 adjuvant Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 238000011109 contamination Methods 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 238000005267 amalgamation Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100776737A CN100551435C (zh) | 2007-03-08 | 2007-03-08 | 小建中胶囊的防潮包衣方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100776737A CN100551435C (zh) | 2007-03-08 | 2007-03-08 | 小建中胶囊的防潮包衣方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101020043A true CN101020043A (zh) | 2007-08-22 |
| CN100551435C CN100551435C (zh) | 2009-10-21 |
Family
ID=38707971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007100776737A Active CN100551435C (zh) | 2007-03-08 | 2007-03-08 | 小建中胶囊的防潮包衣方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100551435C (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258337A (zh) * | 2014-09-29 | 2015-01-07 | 洛阳御平国生物科技有限公司 | 一种针对虚寒腹痛的中药配方 |
-
2007
- 2007-03-08 CN CNB2007100776737A patent/CN100551435C/zh active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258337A (zh) * | 2014-09-29 | 2015-01-07 | 洛阳御平国生物科技有限公司 | 一种针对虚寒腹痛的中药配方 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100551435C (zh) | 2009-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101181354B (zh) | 五味子化学成分群提取物及其制备工艺 | |
| CN101999626A (zh) | 一种复合糖颗粒的制备方法 | |
| CN103655639A (zh) | 一种螺旋藻片剂及其制备方法 | |
| CN106581685A (zh) | 改善中药提取液喷雾干燥时粘壁的方法以及辅料组合物 | |
| CN101878907A (zh) | 一种沙棘叶有效成分制备的系列保健品 | |
| CN105616407A (zh) | 一种硫酸氢氯吡格雷固体制剂及其制备方法 | |
| CN100551435C (zh) | 小建中胶囊的防潮包衣方法 | |
| CN101249224B (zh) | 提高维c银翘片稳定性的方法 | |
| CN115364166B (zh) | 一种提升工艺稳定性以及产品品质的维脂康胶囊的制备方法 | |
| CN112220859B (zh) | 一种复方中药制剂制备工艺 | |
| CN107028895B (zh) | 一种枸杞多糖颗粒剂及其制备方法 | |
| CN101879211A (zh) | 一种清热利咽止痛中药制剂及其制备方法 | |
| CN101618116B (zh) | 粉末包衣制备养血当归胶囊的方法 | |
| CN114869855A (zh) | 用于填充胶囊的尪痹清膏微丸型组合物及其制备方法 | |
| CN110448532B (zh) | 一种灵芝多糖颗粒及其制备方法和应用 | |
| CN106361708A (zh) | 高密度微丸丸芯及其制备方法 | |
| CN115227755B (zh) | 一种七味养心健脾组合物胶囊的产业化工艺 | |
| CN114848742B (zh) | 一种清肺抑火胶囊制备方法 | |
| CN102028843B (zh) | 一种防治月经不调的中药组合物的制备方法 | |
| CN116806999B (zh) | 一种灵芝孢子粉片剂及其制备方法 | |
| CN100431580C (zh) | 三金片的制备方法 | |
| CN1698701A (zh) | 一种痛风舒片及其制备方法 | |
| CN109700775A (zh) | 盐酸雷尼替丁片的制备方法 | |
| CN103055121A (zh) | 一种清热利咽药物的制备方法 | |
| CN103040952B (zh) | 一种当飞利肝宁胶囊的防潮包衣方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20120606 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2011990000190 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20120606 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2012990000269 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20130608 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2012990000269 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20130608 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2013990000362 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20140611 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2013990000362 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20140612 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2014990000458 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20110523 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2011990000190 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20150807 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2014990000458 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20150813 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2015990000676 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20160812 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2015990000676 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20160816 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2016520000008 |
|
| PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20170920 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2016520000008 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moistureproof coating method of Xiaojianzhong capsule Effective date of registration: 20171026 Granted publication date: 20091021 Pledgee: Agricultural Bank of China, Limited by Share Ltd, Xifeng county subbranch Pledgor: Taihe Pharmaceutical Co., Ltd., Guizhou Registration number: 2017520000011 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20201116 Granted publication date: 20091021 Pledgee: Agricultural Bank of China Limited by Share Ltd. Xifeng county subbranch Pledgor: GUIZHOU TAIHE PHARMACEUTICAL Co.,Ltd. Registration number: 2017520000011 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Moisture proof coating method of Xiaojianzhong capsule Effective date of registration: 20201118 Granted publication date: 20091021 Pledgee: Agricultural Bank of China Limited by Share Ltd. Xifeng county subbranch Pledgor: GUIZHOU TAIHE PHARMACEUTICAL Co.,Ltd. Registration number: Y2020520000021 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |