CN101019929A - Chinese medicine composition for treating femoral head necrosis and its prepn process - Google Patents
Chinese medicine composition for treating femoral head necrosis and its prepn process Download PDFInfo
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Abstract
The present invention is one kind of Chinese medicine composition with the functions of replenishing marrow, benefiting qi, promoting blood circulation to disperse blood clots and detoxicating for treating femoral head necrosis, and its preparation process. The Chinese medicine composition is prepared with pilose antler, musk, red ginseng, frankincense, myrrh and other six kinds of Chinese medicinal materials in the weight proportion as shown. The preparation process includes crushing, 100 mesh sieving, mixing, irradiation to sterilize, adding pharmaceutically acceptable supplementary material and other steps for preparing medicine powder or capsule.
Description
(1) technical field
The present invention relates to a kind of have mend marrow QI invigorating, blood circulation and promoting silt, search wind antidotal function; The Chinese medicine composition that is used for the treatment of the femur head necrosis that a variety of causes causes, and the preparation method of this pharmaceutical preparation.
(2) background technology
Glue bone ischemic necrosis is difficult disease, the frequently-occurring disease of orthopedics department, and with hip joint stationarity pain, joint motion is limited, and walk lamely and lower limb muscles atrophy etc. is main performance.Owing to the abuse of hormone, the fracture incidence rate also rises in recent years, and the incidence rate of primary disease is also in rising trend.The western medicine viewpoint of its cause of disease is by following summary:
1, wound: i.e. IFFN, dislocation of hip joint, iatrogenic injury, several situations of femoral head crush injury.
2, thromboembolism: i.e. sicklemia, fat embolism match, several situations of decompression sickness.
3, bone marrow lesion, fatty marrow dystopy, interval syndrome, several situations of poisoning.
4, bone loss: i.e. wound, alcoholism, adrenocortical hormone, high ferro osteoporosis, several situations of osteoporosis.
Doctor trained in Western medicine is generally taked Therapeutic Method as described below according to the state of an illness: non-operative treatment is electrostimulation, hyperbaric oxygentherapy etc., though its method can alleviate some pain and there is certain curative effect the walking aspect, long-term effect is difficult to estimate.Generally tend to operative treatment abroad, generally acknowledge that the preferable operation of effect roughly has following several: total joint replacement, the artificial femoral head replacement, metal cup forms art, fusion of hip joint, hard matter bone is planted art, osteotomy.Adopt the western medical treatment method, painful big concerning the patient though its operation has certain curative effect, the expense height, some patient performs the operation for fear and delays the best treatment time limit, causes lifelong disability.
Motherland's medical science thinks that the reason that primary disease takes place is natural endowment deficiency, wound strain and invades outward.Congenital defect is the endogenous cause of ill that primary disease takes place, and congenital defect then human body must be empty, and weakened defensive QI very easily is subjected to the effect of exopathogenic factor and falls ill.The latter then is an exopathogenic factor, makes the capable mistake degree of blood or undermines internal organs as wound, and internal organs are impaired and then cause QI-blood circulation not smooth; Wound can also cause directly that the femoral head blood supply insufficiency makes the generation of primary disease.Primary disease belongs to the category of Chinese medicine " osteomyelitis " disease, generally is divided into:
1. blood stasis blocking type mostly is due to the wound;
2. cold-dampness type mostly is due to the heresy of experiencing cold-damp;
3. interior damage type mostly is due to the pathogenic heat;
4. strain type mostly is due to the chronic strain;
5. caused by liver and kidney deficiency type, disease causes caused by liver and kidney deficiency for a long time.
The different treatments of disease classification are also not quite identical, because the primary disease course of disease is longer, curative effect is relatively poor, so single proved recipe of many treatment primary disease appears in various places, used folk prescription mostly is decoction, and the patient takes inconvenience, so be difficult to the course of treatment effectively keep thereby can not reach therapeutic effect.
(3) summary of the invention
[problem that will solve]
One of purpose of the present invention provide a kind of have mend the marrow QI invigorating, blood circulation and promoting silt is searched wind antidotal function, is used for the treatment of the Chinese medicine composition of the femur head necrosis that a variety of causes causes and the prescription of pharmaceutical preparation thereof, and determined curative effect, toxic and side effects is little.
Another object of the present invention provides the preparation method of this Chinese medicine composition.
[technical scheme]
The inventor is through for many years clinical research, invented to have the marrow of benefit QI invigorating, blood circulation and promoting silt, search wind antidotal function on the basis of secret prescription handed down in the family from generation to generation " Qingzhou Wu Shi femur health "; Be used for the treatment of the Chinese medicine composition and the pharmaceutical preparation thereof of the femur head necrosis that a variety of causes causes, and the preparation method of this pharmaceutical preparation.This pharmaceutical preparation employing has invigorating kidney-YANG, benefiting essence-blood, bone and muscle strengthening, accent towards a Cornu Cervi Pantotrichum of appointing effect; Have that strongly invigorating primordial QI, multiple arteries and veins take off admittedly, the Radix Ginseng Rubra of nourishing qi to stop effect; Borneolum Syntheticum, Moschus moschiferous perfume (or spice) with promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain effect; Have promoting flow of QI and blood, the Olibanum of subduing swelling and relieving pain effect, Myrrha, Radix Notoginseng; Pyritum with dissipating blood stasis, synthetism, analgesic effect; The Pulvis Fellis Suis that has the Semen Strychni Pulveratum of removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating function and have an effects for removing toxic heat is that raw material is made.This pharmaceutical preparation has determined curative effect, and is easy to use, the characteristics that expense is low.Wherein:
Cornu Cervi Pantotrichum is the young horn of the unossified close living fine hair of stag of animal in deer family Cervus nippon Temminck Cervus nippon Temminck or Cervus elaphus linnaeus Cervus elaphusLinnaeus.The former practises title " pilose antler of sika ", and the latter practises title " cervus elaphus linnaeus ".Summer, autumn, saw was got Cornu Cervi Pantotrichum, after processing, dried in the shade or dried.Concocting method and specification have piece of antler and Pulveratum Cornu Cervi Pantotrichum.The tradition traditional Chinese medical science thinks that Cornu Cervi Pantotrichum is warm in nature, sweet in the mouth, salty.Return kidney, Liver Channel, have invigorating kidney-YANG, benefiting essence-blood, bone and muscle strengthening, accent towards the function of appointing, holding in the palm sore.Be used for the treatment of that sexual impotence spermatorrhea, cold womb are infertile, weakness and emaciation, Mental fatigue, fear of cold, dizzy, Hiccough and deaf, spinal column cold type of pain, muscles and bones flaccidity are soft, bleeding not during menses, carbuncle of yin nature are not held back.
Radix Ginseng Rubra is the dry root of cultivation product (practise and claim " Park Ginseng ") after steaming of Araliaceae Radix Ginseng Panax ginseng C.A.Mey..Excavate autumn, clean, and after steaming, drying.Concocting method is for running through, shave, and drying or time spent smash to pieces.The tradition traditional Chinese medical science thinks that Radix Ginseng Rubra is warm in nature, sweet in the mouth, little hardship.Return spleen, lung, heart channel.Have that strongly invigorating primordial QI, multiple arteries and veins take off admittedly, the function of nourishing qi to stop.Be used for the treatment of weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis, heart failure, cardiogenic shock.Moschus is the dry secretions in the ripe male body note capsule of animal in deer family woods Moschus moschiferous Moschus berezovskii Flerov, horse Moschus moschiferous MoschussifanicusPrzewalski or former Moschus moschiferous Moschus moschiferus Linnaeus.Wild Moschus moschiferous how hunt by the extremely inferior in the winter time spring, after trapping, extracts sachet, dries in the shade, and practises claiming " hair shell Moschus "; Cut sachet open, remove softgel shell, practise title " Moschus core ".The family Moschus moschiferous is directly taken out Moschus core from its sachet, dry in the shade or use the exsiccator close drying.
[process of preparing Chinese medicine] gets a mao shell Moschus, removes softgel shell, takes out Moschus core, removes impurity, and the time spent grinds.The tradition traditional Chinese medical science thinks that Moschus is warm in nature, acrid in the mouth.Return spleen, heart channel.Has the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, the function of reducing swelling and alleviating pain.Be used for the treatment of the calentura coma, the apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, the attacked by pestiferous factors stupor, amenorrhea, note of the ancient Chinese abdominal mass, the difficult labour stillborn fetus, trusted subordinate's sudden pain, the carbuncle scrofula, laryngopharynx swelling and pain falls and pounces on the pain of injury, the arthralgia pain numbness.
Olibanum is that Burseraceae Boswellia carterii Boswellia carterii Birdw. and congener B.bhaw-dijiana Birdw. bark ooze out resin.Usually be divided into Somalia's Olibanum and Ethiopia's Olibanum, every kind is divided into Olibanum pearl and former Olibanum again.The tradition traditional Chinese medical science thinks that Olibanum is warm in nature, acrid in the mouth, hardship.Go into the heart, liver, spleen channel.Have regulating qi and activating blood, analgesic therapy chases after malicious function.Cure mainly coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, congestion twinge in puerperal.For oral administration: as to fry in shallow oil soup or go into ball, diffusing; External: grind into powder to transfer and apply.
Myrrha is olive subject plant Herba Violae tree Commiphora myrrha Engl., breathes out the dry resin of Herba Violae tree Commiphora molmol Eng1..Be divided into natural Myrrha and gum opoponax.The tradition traditional Chinese medical science thinks there be not the property of medicine to put down bitter in the mouth.Return liver heart channel.Has promoting flow of QI and blood, the function of subduing swelling and relieving pain blood.Be used for ulcer sore pain, traumatic blood stasis, amenorrhea and mass in the abdomen, all pains of breast abdomen; But external expelling pus and promoting granulation.
Pyritum is a sulfide-based mineral yellow iron mine family pyrite.Main ferrous disulfide (the FeS that contains
2).After excavating, remove impurity.The tradition traditional Chinese medical science thinks that Pyritum is flat, acrid in the mouth.Return Liver Channel.Has dissipating blood stasis, synthetism, analgesic function.Be used for tumbling and swelling, the muscles and bones folding is hindered.
[process of preparing Chinese medicine] Pyritum is removed impurity, cleaning, drying.Time spent smashes.
Pyritum (calcined): get clean Pyritum, forge to dark red according to forging method (appendix II D), quench in vinegar to surface is pitchy, and gloss disappears and is loose.Every 100kg Pyritum is used vinegar 30kg.
Go into the diffusing clothes of ball more, should be decocted first if go into decoct.Suitable amount used externally.
Squama Manis is the scute of Manidae animal Squama Manis Manis pentadactyla Linnaeus.Collect scute, clean, dry.The tradition traditional Chinese medical science is thought the Squama Manis cold nature, salty in the mouth.Return liver, stomach warp.Has the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, the function of expel wind to dredge collateral.Be used for amenorrhea note of the ancient Chinese abdominal mass, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
[process of preparing Chinese medicine] Squama Manis: remove impurity, cleaning, drying.Stir-baked SQUAMA MANITIS: get clean Squama Manis, size separately, according to scald method (appendix II D) with stir-baking in sand to heaving cleaning, drying.Time spent smashs to pieces.
Semen Strychni Pulveratum is the process of preparing Chinese medicine processed goods of the dry mature seed of loganiaceae plant Semen Strychni Strychnos nux-vomica L..The mature fruit of gathering winter is taken out seed, dries, and is ground into fine powder, behind Chinese Pharmacopoeia Semen Strychni [assay] method mensuration strychnine content down, adds appropriate amount of starch, makes content up to specification, mixing, promptly.The tradition traditional Chinese medical science thinks that Semen Strychni Pulveratum is warm in nature, flavor temperature, bitter; Very toxic.Return liver, spleen channel.Has removing obstruction in the collateral to relieve pain, the function of mass dissipating and swelling eliminating.Be used for the treatment of rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.
[process of preparing Chinese medicine] Semen Strychni: remove impurity.Semen Strychni (processed): get clean Semen Strychni, according to pharmacopeia scald method (appendix II D) with stir-baking in sand to heaving and apparent sepia or dark-brown.Go into the diffusing usefulness of ball.
Pulvis Fellis Suis is the biliary dry product of porcine animals pig Sus scrofa dommestica Brisson..Get Fel Sus domestica, filter, dry, pulverizing, promptly.The tradition traditional Chinese medical science thinks that Pulvis Fellis Suis is cold in nature, bitter in the mouth.Return liver, gallbladder, lung, large intestine channel.Have heat clearing away, moisturize, detoxifcation, the function of relieving cough and asthma.It is dry thirsty to be used for calentura, conjunctival congestion, and sore throat, jaundice, pertussis, asthma is had loose bowels, dysentery, constipation, carbuncle pyogenic infections from tumour or sore.
Radix Notoginseng is the dry root of panax araliaceae plant Panax notoginseng (Burk.) F.H.Chen.Excavate before the flowers are in blossom autumn, cleans, and separates main root, supporting root and stem foot, drying.Supporting root is practised and is claimed " rib ", and stem foot is practised title " clip ".The tradition traditional Chinese medical science thinks that Radix Notoginseng is warm in nature, sweet in the mouth, little hardship.Return liver, stomach warp.Has the dissipating blood stasis hemostasis, the function of subduing swelling and relieving pain.Be used for the treatment of spitting of blood, spit blood, epistaxis is had blood in stool, metrorrhagia, and traumatic hemorrhage, the breast abdomen twinges, tumbling and swelling.
Borneolum Syntheticum is that the trunk of Dipterocarpaceae aiphyllium Borneolum Syntheticum Dryobalanops aromatica Gaerth. cools off the crystallization that gets through distillation, is dextro Borneolum Syntheticum; Or be the leaf of feverfew Herba Blumeae Balsamiferae Blumea balsamifera DC., through distillation cooling and the further crystallization of processing gained, be left-handed Borneolum Syntheticum.The tradition traditional Chinese medical science thinks that Borneolum Syntheticum is arduous and is slightly cold to have the refreshment of having one's ideas straightened out, the effect of clearing away heat to alleviate pain, externally used detumescence pain relieving.
Following prescription is adopted in this Chinese medicine composition and pharmaceutical preparation thereof: 60～200 parts in Cornu Cervi Pantotrichum, 2～10 parts in Moschus, 50～300 parts of Radix Ginseng Rubra, 20～80 parts of Olibanums, 20～80 parts of Myrrhas, 60～200 parts of Pyritums, 50～300 parts of Squama Maniss, 10～40 parts of Semen Strychni Pulveratums, 20～60 parts of Fel Sus domestica powder, 10～60 parts of Scolopendras, 50～300 parts of Radix Notoginseng.
The optimization formula of purpose Chinese medicine composition of the present invention is: 100～150 parts in Cornu Cervi Pantotrichum, 3～5 parts in Moschus, 80～150 parts of Radix Ginseng Rubra, 30～50 parts of Olibanums, 30～50 parts of Myrrhas, 100～150 parts of Pyritums, 80～120 parts of Squama Maniss, 10～30 parts of Semen Strychni Pulveratums, 30～50 parts of Fel Sus domestica powder, 30～50 parts of Scolopendras, 80～120 parts of Radix Notoginseng.
The optimization formula of Chinese medicine composition of the present invention is: 120 parts in Cornu Cervi Pantotrichum, 4 parts in Moschus, 100 parts of Radix Ginseng Rubra, 40 parts of Olibanums, 40 parts of Myrrhas, 120 parts of Pyritums, 100 parts of Squama Maniss, 20 parts of Semen Strychni Pulveratums, 40 parts of Fel Sus domestica powder, 40 parts of Scolopendras, 100 parts of Radix Notoginseng.
Can add some flavor accessory drugss in the above-mentioned Chinese medicine composition, as a kind of in Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several, wherein the addition of Radix Aconiti Lateralis Preparata is that the addition of 60-120 weight portion, the Cortex Eucommiae is that the addition of 30-80 weight portion, Radix Achyranthis Bidentatae is that the addition of 30-80 weight portion, Sanguis Draxonis is that the addition of 100-150 weight portion, Eupolyphaga Seu Steleophaga is the 30-80 weight portion.
The present invention also provide a kind of have mend the marrow QI invigorating, blood circulation and promoting silt is searched wind antidotal function, is used for the treatment of Chinese medicine composition composition powders, capsule, granule, the tablet of the femur head necrosis that a variety of causes causes, the preparation method of pill pharmaceutical preparation:
(4) specific implementation method
Embodiment one
Embodiment 1: the method for preparing this pharmaceutical preparation powder:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g,
Method for making: above ten flavor medicines, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), give birth to Pyritum, Squama Manis (processed), Scolopendra, Radix Notoginseng pulverize separately become fine powder, crosses 100 mesh sieves, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization, be distributed into powder, promptly.
Embodiment 2: the method for preparing this pharmaceutical preparation capsule:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g,
Method for making: above ten flavor medicines, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), give birth to Pyritum, Squama Manis (processed), Scolopendra, Radix Notoginseng pulverize separately become fine powder, crosses 100 mesh sieves, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization, encapsulated, promptly.
Embodiment 3: the method for preparing this pharmaceutical preparation capsule:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g,
Method for making: above ten flavor medicines, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Radix Notoginseng, Squama Manis (processed) pulverize separately and become fine powder, standby; Olibanum, Myrrha, Pyritum, Fel Sus domestica powder, Scolopendra are given as one thinks fit cataclasm, and the decocting that adds 5～15 times of amounts respectively boils 2-3 time, and each 1-3 hour, extract fully, merge extractive liquid,, concentrating under reduced pressure become dried cream, pulverize, and cross 100 mesh sieves, and be standby; With above-mentioned all medicated powder and Semen Strychni Pulveratum mixing, add the Moschus facing-up again, radiation sterilization is distributed into powder or capsule or adds Chinese medicine preparation acceptable additives and makes various oral drug preparations.
Embodiment 4: the method for preparing this pharmaceutical preparation capsule:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Herba Asari 60g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata, Herba Asari are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization, encapsulated, promptly.
Embodiment 5: the method for preparing this pharmaceutical preparation tablet:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Herba Asari 60g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Olibanum, Myrrha, Pyritum, Fel Sus domestica powder, Scolopendra etc. are given as one thinks fit cataclasm, and the decocting that adds 5～15 times of amounts respectively boils 2-3 time, and each 1-3 hour, extract fully, merge extractive liquid,, concentrating under reduced pressure become dried cream, pulverize, and cross 100 mesh sieves, and be standby; With above-mentioned all medicated powder and Semen Strychni Pulveratum mixing, add the Moschus facing-up again, radiation sterilization adds the magnesium stearate of 5-6% again, mixing, tabletting, sugar coating or film-coat, promptly.
Embodiment 6; The method for preparing this pharmaceutical preparation tablet:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Herba Asari 60g.
Method for making: above 12 flavor medicines, get Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata, Herba Asari are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization adds 5% magnesium stearate again, mixing, tabletting, sugar coating or film-coat, promptly.
Embodiment 7: the method for preparing this pharmaceutical preparation capsule:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Cortex Eucommiae 120g, Rhizoma Cibotii 150g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, the Cortex Eucommiae, Rhizoma Cibotii are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization, encapsulated, promptly.
Embodiment 8: the method for preparing this pharmaceutical preparation tablet:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Cortex Eucommiae 120g, Rhizoma Cibotii 150g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, the Cortex Eucommiae, Rhizoma Cibotii are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization adds 5% magnesium stearate again, mixing, tabletting, sugar coating or film-coat, promptly.
Embodiment 9: the method for preparing this pharmaceutical preparation capsule:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Dipsaci 150g, Rhizoma Drynariae 150g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Dipsaci, Rhizoma Drynariae are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization, encapsulated, promptly.
Embodiment 10: the method for preparing this pharmaceutical preparation tablet:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 49g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Dipsaci 150g, Rhizoma Drynariae 150g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Dipsaci, Rhizoma Drynariae are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization adds 5% magnesium stearate again, mixing, tabletting, sugar coating or film-coat, promptly.
Embodiment 11: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g,
Method for making: above ten flavor medicines, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), give birth to Pyritum, Squama Manis (processed), Scolopendra, Radix Notoginseng pulverize separately become fine powder, cross 100 mesh sieves, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, make the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 12: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Dipsaci 150g, Rhizoma Drynariae 150g.
Method for making: above 12 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Dipsaci, Rhizoma Drynariae are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, and makes the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 13: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Radix Dipsaci 150g, Rhizoma Drynariae 150g.
Method for making: above 13 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata, Radix Dipsaci, Rhizoma Drynariae are given as one thinks fit cataclasm, the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, and makes the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 14: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Radix Achyranthis Bidentatae 200g, Fructus Chaenomelis 150g.
Method for making: above 13 flavor medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata, Radix Achyranthis Bidentatae, Fructus Chaenomelis are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, and makes the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 15: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g.
Method for making: above ten Herba indigoferae Pseudotinctoriae, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, and makes the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 16: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g.
Method for making: above ten Herba indigoferae Pseudotinctoriae, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), give birth to Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata pulverize separately become fine powder, cross 100 mesh sieves, mixing adds Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, add an amount of Mel or water or gelatinized corn starch or rice paste or Different concentrations of alcohol, make the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 17: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g,
Method for making: above ten flavor medicines, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), give birth to Pyritum, Squama Manis (processed), Scolopendra, Radix Notoginseng pulverize separately become fine powder, cross 100 mesh sieves, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste or Different concentrations of alcohol, make the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 18: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Herba Asari 80g, Radix Achyranthis Bidentatae 200g, Fructus Chaenomelis 150g.
Method for making: above ten four Chinese medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata, Herba Asari, Radix Achyranthis Bidentatae, Fructus Chaenomelis are given as one thinks fit cataclasm, the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste or Different concentrations of alcohol, makes the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment 19: the method for preparing this pharmaceutical preparation pill:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Radix Aconiti Lateralis Preparata 120g, Cortex Eucommiae 120g, Radix Achyranthis Bidentatae 200g, Fructus Chaenomelis 150g.
Method for making: above ten four Chinese medicines, get Cornu Cervi Pantotrichum, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Radix Ginseng Rubra, Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis are given as one thinks fit cataclasm, the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, and makes the pill of difformity specification, radiation sterilization, packing, promptly.
The method of embodiment 20 these pharmaceutical preparation pills of preparation:
Prescription: Cornu Cervi Pantotrichum 120g, Radix Ginseng Rubra 100g, Olibanum (processed) 40g part, Myrrha (processed) 40g, living Pyritum 120g part, Squama Manis (processed) 100g, Semen Strychni Pulveratum 20g, Pulvis Fellis Suis 40g, Scolopendra 40g, Radix Notoginseng powder 100g, Cortex Eucommiae 120g, Radix Achyranthis Bidentatae 200g, Fructus Chaenomelis 150g.
Method for making: above 13 flavor medicines, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Squama Manis (processed), Scolopendra, pulverize separately and become fine powder, cross 100 mesh sieves, standby; Olibanum (processed), Myrrha (processed), living Pyritum, Radix Notoginseng, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Fructus Chaenomelis are given as one thinks fit cataclasm, and the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, and extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing adds an amount of Mel or water or gelatinized corn starch or rice is stuck with paste, and makes the pill of difformity specification, radiation sterilization, packing, promptly.
Embodiment two:
Be the therapeutic effect of proof medicine of the present invention to femur head necrosis, the present invention is through 262 routine case observations, and selection medical history, age, sex and suitable 120 matched groups of ischemia femur head necrosis patient of original therapy method are observed.95 on January 1, is played " the Chinese medicine disease is diagnosed the standard of recuperating " of enforcement by the national Chinese medicine of foundation management board, as the clinical case diagnostic criteria.Wherein test group 262 examples are taken pharmaceutical composition of the present invention " Qingzhou Wu Shi femur health ball ", obey 1 ball (quite medical material 6g) at every turn, every day 3 times, matched group 120 examples are taken promoting blood air circulation and building up bone sheet (Great Wall, Beijing pharmaceutical manufacturing), 12 of each clothes, every day 3 times, 6 months is a course of treatment.Under equal conditions treat observation, write down 4 index treatments such as two groups of patient's hip pains, limping, function of joint, iconography front and back integration respectively and change.Clinical trial proves that significant difference is arranged.Test group total effective rate 86.0%, obvious effective rate 66.2%, 40.6%, two group of diversity evident in efficacy of matched group total effective rate 72.6% obvious effective rate (P＜0.05), the test group curative effect is better than the matched group curative effect, illustrates that pharmaceutical composition of the present invention is better to treatment femur head necrosis curative effect.
Claims (10)
1, a kind of have mend the marrow QI invigorating, blood circulation and promoting silt, search wind antidotal function, be used for the treatment of the Chinese medicine composition and the pharmaceutical preparation thereof of the femur head necrosis that a variety of causes causes, this Chinese medicine composition is made according to following weight part ratio by following raw materials according: 60～200 parts in Cornu Cervi Pantotrichum, 2～10 parts in Moschus, 50～300 parts of Radix Ginseng Rubra, 20～80 parts of Olibanums, 20～80 parts of Myrrhas, 60～200 parts of Pyritums, 50～300 parts of Squama Maniss, 10～40 parts of Semen Strychni Pulveratums, 20～60 parts of Fel Sus domestica powder, 10～60 parts of Scolopendras, 50～300 parts of Radix Notoginseng.
2, according to claim 1 described Chinese medicine composition, it is characterized in that the parts by weight of raw materials ratio in the described Chinese medicine composition is: 120 parts in Cornu Cervi Pantotrichum, 4 parts in Moschus, 100 parts of Radix Ginseng Rubra, 40 parts of Olibanums, 40 parts of Myrrhas, 120 parts of Pyritums, 100 parts of Squama Maniss, 20 parts of Semen Strychni Pulveratums, 40 parts of Fel Sus domestica powder, 40 parts of Scolopendras, 100 parts of Radix Notoginseng.
3, according to claim 1 or 2 described Chinese medicine compositions, it is characterized in that: can also add a kind of in Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several in the described Chinese medicine composition, wherein the addition of Radix Aconiti Lateralis Preparata is that the addition of 60-120 weight portion, the Cortex Eucommiae is that the addition of 30-80 weight portion, Radix Achyranthis Bidentatae is that the addition of 30-80 weight portion, Sanguis Draxonis is that the addition of 100-150 weight portion, Eupolyphaga Seu Steleophaga is the 30-80 weight portion.
4,, it is characterized in that the flavour of a drug in its prescription composition comprise all sources of stipulating in the pharmacopeia and concoct specification according to claim 1 or 2 or 3 described Chinese medicine compositions.
5, according to claim 1 or 2 or 3 described Chinese medicine compositions, it is characterized in that its preparation method is: above flavour of a drug, get Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Olibanum, Myrrha, Pyritum, Squama Manis, Scolopendra, Radix Notoginseng and/or Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, a kind of in the Herba Asari or several, pulverize separately becomes fine powder, cross 100 mesh sieves, add Semen Strychni Pulveratum again, Pulvis Fellis Suis, the Moschus facing-up, mixing, radiation sterilization is distributed into powder or capsule or adds Chinese medicine preparation acceptable additives and makes various suitable pharmaceutical preparatioies.
6, according to claim 1 or 2 or 3 described Chinese medicine compositions, its preparation method can also for: Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Radix Notoginseng, Squama Manis pulverize separately become fine powder, and be standby; A kind of in Olibanum, Myrrha, Pyritum, Fel Sus domestica powder, Scolopendra and/or Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several, give as one thinks fit cataclasm, the decocting that adds 5～15 times of amounts respectively boils 2-3 time, each 1-3 hour, extract fully merge extractive liquid,, concentrating under reduced pressure becomes dried cream, pulverize, cross 100 mesh sieves, standby; With above-mentioned all medicated powder and Semen Strychni Pulveratum mixing, add the Moschus facing-up again, radiation sterilization is distributed into powder or capsule or adds Chinese medicine preparation acceptable additives and makes various suitable pharmaceutical preparatioies.
7, according to claim 1 or 2 or 3 described Chinese medicine compositions, its preparation method can also for: Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Radix Notoginseng, Squama Manis pulverize separately become fine powder, and be standby; A kind of in Olibanum, Myrrha, Pyritum, Fel Sus domestica powder, Scolopendra and/or Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several, give as one thinks fit cataclasm, add 5～8 times of amount Different concentrations of alcohol liquid reflux, extract, 2-3 time, each 0.5-2 hour, extract fully merge extractive liquid,, decompression recycling ethanol also is condensed into dried cream, pulverize, cross 100 mesh sieves, standby; With above-mentioned all medicated powder and Semen Strychni Pulveratum mixing, add the Moschus facing-up again, radiation sterilization is distributed into powder or capsule or adds Chinese medicine preparation acceptable additives and makes various suitable pharmaceutical preparatioies.
8, according to claim 1 or 2 or 3 described Chinese medicine compositions, its preparation method can also for: Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Radix Notoginseng, Squama Manis pulverize separately become fine powder, and be standby; A kind of in Olibanum, Myrrha, Pyritum, Fel Sus domestica powder, Scolopendra and/or Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several, give as one thinks fit cataclasm, add 5～8 times of amount Different concentrations of alcohol liquid reflux, extract, 2-3 time, each 0.5-2 hour, extract fully merge extractive liquid,, decompression recycling ethanol also is condensed into dried cream, pulverize, cross 100 mesh sieves, standby; With above-mentioned all medicated powder and Semen Strychni Pulveratum mixing, add the Moschus facing-up again, radiation sterilization is distributed into powder or capsule or adds Chinese medicine preparation acceptable additives and makes various suitable pharmaceutical preparatioies.
9, according to claim 1 or 2 or 3 described Chinese medicine compositions, its preparation method can also for: get ethanol liquid reflux, extract, 2-3 time that Cornu Cervi Pantotrichum, Radix Ginseng Rubra, Radix Notoginseng add 5～8 times of amounts 75%, each 0.5-2 hour, extract fully, merge extractive liquid,, decompression recycling ethanol also is condensed into dried cream, pulverizes, and is standby; The Squama Manis pulverize separately becomes fine powder, and is standby; A kind of in Olibanum, Myrrha, Pyritum, Fel Sus domestica powder, Scolopendra and/or Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several, give as one thinks fit cataclasm, the decocting that adds 5～15 times of amounts boils 2-3 time, each 1-3 hour, merge extractive liquid,, concentrating under reduced pressure become dried cream, pulverize, cross 100 mesh sieves, standby; With above-mentioned all medicated powder and Semen Strychni Pulveratum mixing, add Moschus facing-up radiation sterilization again, be distributed into powder or capsule or add Chinese medicine preparation acceptable additives and make various suitable pharmaceutical preparatioies.
10, according to claim 1 or 2 or 3 described Chinese medicine compositions, its preparation method can also be above flavour of a drug, gets Cornu Cervi Pantotrichum, Squama Manis, Scolopendra, pulverize separately and becomes fine powder, crosses 100 mesh sieves, and is standby; A kind of in Radix Ginseng Rubra, Olibanum, Myrrha, Pyritum, Radix Notoginseng and/or Radix Aconiti Lateralis Preparata, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, Os Canitis, Rhizoma Drynariae, Radix Dipsaci, the Herba Asari or several, give as one thinks fit cataclasm, the water or the Different concentrations of alcohol that add 5～15 times of amounts are respectively extracted, extract fully, decompression and solvent recovery and concentrated extracting solution become dried cream, pulverize, and cross 100 mesh sieves, get the extract fine powder, standby; With above-mentioned two kinds of fine powder mixings, add Semen Strychni Pulveratum, Pulvis Fellis Suis, Moschus facing-up again, mixing, radiation sterilization is distributed into powder or capsule or adds Chinese medicine preparation acceptable additives and makes various suitable pharmaceutical preparatioies.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306718A (en) * | 2014-11-04 | 2015-01-28 | 李娜 | Traditional Chinese medicine for treating phlegm-stagnation subsidiary-channel blocked femoral head necrosis and preparation method thereof |
| CN106138415A (en) * | 2016-09-08 | 2016-11-23 | 四川聚豪生物科技有限公司 | A kind of Chinese medicine composition of the femur head necrosis caused for a variety of causes |
-
2007
- 2007-03-14 CN CNA2007100870141A patent/CN101019929A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306718A (en) * | 2014-11-04 | 2015-01-28 | 李娜 | Traditional Chinese medicine for treating phlegm-stagnation subsidiary-channel blocked femoral head necrosis and preparation method thereof |
| CN106138415A (en) * | 2016-09-08 | 2016-11-23 | 四川聚豪生物科技有限公司 | A kind of Chinese medicine composition of the femur head necrosis caused for a variety of causes |
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