CN104524190A - Medicament for treating rheumatic lumbar disease and preparation method thereof - Google Patents
Medicament for treating rheumatic lumbar disease and preparation method thereof Download PDFInfo
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- CN104524190A CN104524190A CN201510003861.XA CN201510003861A CN104524190A CN 104524190 A CN104524190 A CN 104524190A CN 201510003861 A CN201510003861 A CN 201510003861A CN 104524190 A CN104524190 A CN 104524190A
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Abstract
The invention discloses a medicament for treating rheumatic lumbar disease. The medicament comprises, by weight, 15-30 parts of sealwort, 10-15 parts of stauntonia obovatifoliola roots, 15-20 parts of herba epimedii, 12-25 parts of eucommia ulmoides, 9-12 parts of laciniate begonia herbs, 9-15 parts of raspberries, 9-16 parts of erodium stephanianum willd, 8-16 parts of laurus nobilis fruits, 7-14 parts of honeysuckle stems, 8-12 parts of salvia coccinea, 9-16 pars of roots of Gourian clematis, 7-15 parts of Chinese forgetmenot roots and 8-12 parts of prettyleaf silkvine stems. The medicament has the advantages of being appropriate in compatibility of the selected medicines, conforming to the traditional Chinese medicine and modern medicine research theory, and having the effects of dispelling wind and cold and resolving dampness. The medicament can effectively adjust the body function of a patient, strengthen tendons and bones and remove blood stasis and arthritis, has the advantages of being good in curative effect, achieving curing, enabling rheumatic lumbar disease not to be likely to relapse, and the like, and is worthy of popularization. The medicament has the best effects for various wind cold dampness type lumbar diseases, the medicament sources are easy to obtain, the medicine cost is low, and the burdens of the patient can be reduced.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of medicament and preparation method for the treatment of rheumatic lumbar vertebra sufferer.
Background technology
Lumbar spondylosis is medically the general designation of the lumbar disc diseases such as prolapse of lumbar intervertebral disc, lumbar muscle strain, lumbar vertebra hyperosteogeny, lumbar spondylolisthesis and tuberculosis of spine, belong to the commonly encountered diseases and frequently-occurring disease that heal compared with refractory clinically, treatment will have a strong impact on the normal working and learning of patient not in time.Rheumatic lumbar spondylosis mainly refers to the disease such as rheumatism or rheumatoid lumbago, wind cold-damp lumbago, humid lumbago.
The traditional Chinese medical science think rheumatic lumbar spondylosis many by occupy wetland for a long time or paddle in spite of the rain, exposure to the wind after sweating due to overstrain, clothing are clammy, wind and cold water is wet heresy flood meridians, QI of channels and collaterals blocks, and hyperamization BI-syndrome involved the blood vessels hinders, and QI-blood circulation is not freely formed.Western medicine also think the generation of primary disease with tired, catch cold relevant with humidity.Its pathological manifestations is fibrous tissue edema, causes muscle protection spasm, and Shogakukan shrinks, and affects metabolism and the nutrition of muscle, causes affected tissue easily to produce degeneration, and formation of a specified duration is difficult to the lumbago of curing." Standards of Diagnosis and Treatment lumbago " cloud: " have wind, have wet, have cold, have heat, frustrate sudden strain of a muscle, have congestion, all mark also; Suffer from a deficiency of the kidney it also." with the passing of time this patient delay mostly, recurrent exerbation, weakened body resistance sign of vomitting, and belongs to the card of deficiency in origin and excess in superficiality.Therefore should treating both the principal and secondary aspects of a disease be accomplished in the treatment, curative effect could be consolidated with lasting.
The Chinese patent literature of publication number CN 1985893 A (application number 200510136603.5) discloses a kind of medicine for the treatment of rheumatic lumbago, be made up of the medicine of following weight portion: Semen Nelumbinis 2.2-21.98%, Rhizoma Atractylodis Macrocephalae 2.2-21.98%, Radix Notoginseng 1.1-10.99%, Radix Angelicae Pubescentis 2.2-21.98%, crystal sugar 2.2-21.98%, egg 26.37-65.95%.Application publication number CN 102552446 A(application number 201210048868.X) Chinese patent literature disclose a kind of Chinese medicinal preparation method of external application for curing lumbago due to pathogenic wind-dampness, be prepared from by the raw material of following weight proportioning: Herba speranskiae tuberculatae 23 grams, Radix Aconiti 18 grams, Radix Aconiti Lateralis Preparata 18 grams, Rhizoma Et Radix Notopterygii 18 grams, Radix Angelicae Pubescentis 18 grams, Radix Angelicae Sinensis 14 grams, crude salt 250 grams, vinegar 10 grams.Application publication number CN 103705751 A(application number 201410016718.X) Chinese patent literature disclose a kind of Chinese medicine composition being used for the treatment of lumbago due to pathogenic wind-dampness and preparation method thereof, be made up of the raw medicinal material of following parts by weight: Ramulus Cinnamomi 10-30 weight portion, Paphiopedilum parishii(Rchb. F.) Pfitz 15-25 weight portion, Rhizoma Et Radix Notopterygii 16-31 weight portion, Radix Angelicae Pubescentis 16-31 weight portion, Radix Angelicae Dahuricae 11-21 weight portion, Radix seu Caulis Jasmini lanceolarii 16-25 weight portion, Capreolus Capreolus (Linnaeus). 16-25 weight portion, Radix Pandani Furcati 16-30 weight portion, Fructus Chaenomelis 16-30 weight portion, Bombyx mori L. 12-25 weight portion, Lignum Pini Nodi 14-25 weight portion, Caulis Sinomenii 16-24 weight portion, Resina Liquidambaris 16-31 weight portion, Radix Salviae Miltiorrhizae 16-25 weight portion, Caulis Viticis Cannabifoliae 12-25 weight portion, Chinese mugwort 12-3 weight portion in thousand, Fructus Liquidambaris 12-20 weight portion, Radix Achyranthis Bidentatae 10-21 weight portion, Caulis Spatholobi 16-31 weight portion and Squama Manis 16-31 weight portion.
In prior art, the treatment of rheumatic lumbar spondylosis is taked more to the oral formulations of Chinese medicine and Western medicine or both drug combinations.But the damage that oral drugs cause for Liver and kidney is very large, therapeutic effect is also not fully up to expectations.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, that instant effect, curative effect are short a kind of medicament and preparation method for the treatment of rheumatic lumbar vertebra sufferer.This medicament mild in medicine property and and have no side effect.
Technical scheme of the present invention is:
The medicament for the treatment of rheumatic lumbar vertebra sufferer, is characterized in that, be prepared from by following bulk drugs, be weight portion: Rhizoma Polygonati 15-30; Cattle rattan 10-15; Herba Epimedii 15-20; Cortex Eucommiae 15-25; Herba Begoniae Laciniatae 9-12; Fructus Rubi 9-15; Geranium 9-16; Fructus Lauri nobilis 8-16; Caulis Lonicerae 7-14; Zhu's lip 8-12; Radix seu Caulis fici Martinii grass 9-16; Crow bone fiber crops 7-15; Caulis Periplocae Calophyllae 8-12.
In preferred scheme, Rhizoma Polygonati 20-25; Cattle rattan 11-14; Herba Epimedii 16-19; Cortex Eucommiae 18-22; Herba Begoniae Laciniatae 10-11; Fructus Rubi 11-13; Geranium 11-14; Fructus Lauri nobilis 10-14; Caulis Lonicerae 9-12; Zhu's lip 9-11; Radix seu Caulis fici Martinii grass 11-14; Crow bone fiber crops 10-12; Caulis Periplocae Calophyllae 9-11.
Be more preferably, Rhizoma Polygonati 22.5; Cattle rattan 12.5; Herba Epimedii 17.5; The Cortex Eucommiae 20; Herba Begoniae Laciniatae 10.5; Fructus Rubi 12; Geranium 12.5; Fructus Lauri nobilis 12; Caulis Lonicerae 10.5; Zhu's lip 10; Radix seu Caulis fici Martinii grass 12.5; Crow bone fiber crops 11; Caulis Periplocae Calophyllae 10.
The medicament for the treatment of rheumatic lumbar vertebra sufferer, the preparation method of described decoction is:
(1) Rhizoma Polygonati section, gets muscovado and adds water and dissolve (medical material muscovado per jin 3 liang), be sprinkled in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, for subsequent use;
(2) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 100kg, with refining Adeps caprae seu ovis 20kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 100kg Cortex Eucommiae Sal 2kg);
(3) medical material after being processed step (1)-(2) and cattle rattan, Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Caulis Lonicerae, Zhu's lip, Radix seu Caulis fici Martinii grass, black bone fiber crops and Caulis Periplocae Calophyllae are together placed in non iron container, add pure water and the yellow wine of 6-10 times amount, soak 3-6 hour (preferably soaking 4-5 hour), intense fire boils, turn slow fire boiling 1-2 hour (preferably decocting 1.5 hours), filter, obtain decocting liquid;
(4) cooled by above-mentioned decocting liquid, 115 DEG C of sterilizings, encapsulation, to obtain final product.
The preparation method of the decoction of above-mentioned treatment rheumatic lumbar vertebra sufferer, preferred scheme is, in step (3), the ratio of pure water and yellow wine is 8:1.
The preparation method of the decoction of above-mentioned treatment rheumatic lumbar vertebra sufferer, preferred scheme is, in step (4), sterilization time is 1.5-3.5 hour (preferred sterilization time is 2-3 hour, and the sterilization time be more preferably is 2.5 hours).
The preparation method of described pill is:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) by gained fine medicinal material powder mixing in step (1), sieve for subsequent use;
(3) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 10kg, with refining Adeps caprae seu ovis 2kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 10kg Cortex Eucommiae Sal 0.2kg);
(4) Herba Epimedii silk step (3) processed and the Cortex Eucommiae and Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are together placed in non iron container, add the pure water of 5-9 times amount, soak 2-3 hour (preferably soaking 2.5 hours), intense fire boils, turn slow fire boiling 0.8-1.5 hour (preferably decocting 1.2 hours), filter, obtain decocting liquid;
(5) above-mentioned gained decocting liquid is carried out distilling under reduced pressure, be condensed into paste, add step (2) gained fine powder, stir, make pill according to the processing method of pill, to obtain final product.
The preparation method of the pill of above-mentioned treatment rheumatic lumbar vertebra sufferer, preferred scheme is, the middle 80-120 mesh sieve excessively of step (2) (preferred 90-110 mesh sieve excessively, mistake 100 mesh sieve be more preferably).
The preparation method of described capsule is:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) get butter, put slow fire heat fused in pot, more above-mentioned Herba Epimedii silk is poured into, fry and mix evenly, take out, spread out, dry in the air cool, smash into powder (every Herba Epimedii 100kg, uses butter 25kg) for subsequent use to pieces; The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip, pulverizes;
(3) by gained fine medicinal material powder mixing in step (1)-(2), 120-180 mesh sieve (preferred mistake 150 mesh sieve) is crossed, for subsequent use;
(4) Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are together placed in crock, add 30-40 DEG C of pure water and do not have powder (preferably add 35 DEG C of pure water and do not have powder), soak 2-4 hour (preferably soaking 3 hours), then intense fire boils, fire of larding speech with literary allusions heats decoction twice, first time decocts 40-60 minute (preferably first time decocts 50 minutes), second time decocts 25-45 minute (preferably second time decocts 35 minutes), in decoction process, water is kept not have powder 2-3cm, filter, merge twice decocting liquid;
(5) above-mentioned decocting liquid being evaporated to 70 DEG C of proportions is the extractum of 1.19-1.32, add step (3) gained fine powder, stir, add cane sugar powder, corn starch and calcium hydrogen phosphate (extract powder: cane sugar powder: corn starch: calcium hydrogen phosphate is 7:1.3:1.1:1.4), wet granulation, cross 80 mesh sieves, packaging, to obtain final product.
The preparation method of described tablet is:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) get butter, put slow fire heat fused in pot, more above-mentioned Herba Epimedii silk is poured into, fry and mix evenly, take out, spread out, dry in the air cool, smash into powder to pieces for subsequent use; The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip, pulverizes;
(3) Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are cleaned, dry 45-65 minute (preferably drying 55 minutes for 70 DEG C), be placed in Chinese medicine grinder and be ground into fine powder for 70 DEG C;
(4) by step (1)-(3) gained fine powder mixing, stir, cross 90-130 mesh sieve (preferred mistake 110 mesh sieve), hypromellose, pregelatinized Starch and dextrin (medicated powder: hypromellose: pregelatinized Starch: dextrin is 9:1:0.8:0.7) is added in mixing fine powders, make tablet, to obtain final product.
Scientific formula of the present invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, Be very effective.In addition, excellent results of the present invention also shows:
1,selected by the present invention, medical material compatibility is suitable, meets Chinese medicine and modern medicine research theory, has wind-evil dispelling and cold-evil expelling, removing dampness effect.
2,medicine of the present invention can effectively regulate patient's body function, bone and muscle strengthening, and removing blood stasis arthralgia aggravated by cold, has good effect, cures the advantages such as not easily recurrence, is worthy to be popularized.
3,medicine of the present invention is to various wind and cold wet type lumbar spondylosis best results; Medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Rhizoma Polygonati: base is former: be the rhizome of liliaceous plant Rhizoma Polygonati, P. cyrtonema, hot river Rhizoma Polygonati, P. kingianum, polygonatum cirrhifolium Royle etc.Chemical analysis: the mucous matter of rhizome of Rhizoma Polygonati, starch and sugar.Pharmacological action: 1. antibacterial action; 2. antifungic action; 3. hypotensive effect.Nature and flavor: sweet are flat.Gui Jing: enter spleen, lung, kidney channel.Function cures mainly: invigorating the spleen and replenishing QI, profit cardiopulmonary, bone and muscle strengthening.Control deficient cold and heat, pulmonary tuberculosis hemoptysis, after being ill the empty lack of appetite of body, muscles and bones is weak, rheumatalgia, wind favus disease.
Herba Epimedii: base is former: be the stem and leaf of Berberidaceae plant Herba Epimedii, Epimedium brevicornum or Epimedium sagittatum.Chemical analysis: Herba Epimedii stem, leaf are containing icariine, and leaf is still containing volatile oil, ceryl alcohol, 1 alkane, plant sterol, tannin, oils and fats.Fatty acid in fatty oil has Palmic acid, stearic acid, oleic acid, linoleic acid.Pharmacological action: 1. affect sexual function; 2. inhibitory action is had to microorganism; 3. antitussive, eliminate the phlegm and antiasthmatic effect; 4. other act on: extraction ofHerba Epimedii has hypotensive effect to rabbit, in a small amount the secretion of urine are increased, then suppress it on the contrary in a large number, have inhibitory action to isolated rabbit intestinal, and isolated uterine is first excited rear suppression then, and the oral hyperglycemic rat blood glucose that can make declines.Nature and flavor: Xin Gan, temperature.Gui Jing: enter liver, kidney channel.Function cures mainly: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control sexual impotence erectile problem, dribbling urination, muscles and bones contraction is anxious, and hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.
The Cortex Eucommiae: base is former: this product is the dry bark of the Eucommiaceae plant Cortex Eucommiae.Character: this product be en plaque or both sides slightly toward curls inward, not of uniform size, thick 3-7mm.Outer surface light brown or taupe, have obvious wrinkle or lobe groove stricture of vagina, some barks are thinner, do not remove rough bark, visible significantly hole skin.Inner surface mulberry, smooth.Matter is crisp, frangibility, and section has fine and closely woven, silvery white, rubber thread full of elasticity to be connected.Feeble QI, taste is slightly bitter.Nature and flavor: sweet, temperature.Gui Jing: return liver, kidney channel.Effect: invigorating the liver and kidney, bone and muscle strengthening.Antiabortive.Curing mainly: for lumbago due to renal deficiency. muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.
Herba Begoniae Laciniatae: base is former: be the Herb of Begoniaceae plant Begonia pedatifida.Nature and flavor: " Luchuan book on Chinese herbal medicine ": " sweet, cold." function cures mainly: cure cold cough, rheumatic ostalgia, lumbago, dyspepsia, treating swelling and pain by traumatic injury, furuncle.
Fructus Rubi: base is former: be the immature fruit of rosaceous plant Fructus Rubi, rubus coreanus etc.Chemical analysis: Fructus Rubi is containing organic acid, saccharide and a small amount of vitamin C.Nature and flavor: sweet acid are flat.Gui Jing: " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enter liver, kidney two warp." function cures mainly: invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight.Control sexual impotence, seminal emission, frequency of micturition, incontinence of urine, asthenia, order is dark.
Geranium: base is former: for Huai Niuer Seedling section plant Mang cattle Seedling or Herba Erodii, nepal cranesbill, Siberia geranium and Carolina Cranesbill Herb, tuber person stork grass etc. are with the herb of fruit.Chemical analysis: Mang cattle Seedling is containing volatile oil, and in oil, main component is Geraniol.Again containing Quercetin and other pigments.Pharmacological action: (i) antibacterial action: herb decoct has obvious inhibitory action to micrococcus catarrhalis, staphylococcus aureus, bacterium flexneri, beta chain coccus, streptococcus pneumoniae etc. in vitro; Wherein contained tannic acid antibacterially has certain influence to it.(ii) antivirus action: herb decoct has obvious inhibitory action to the section 68-1 strain of influenza A virus capital, Asia and the strain of parainfluenza virus I type celestial platform.Nature and flavor: toil are flat.Function cures mainly: dispel the wind, and invigorates blood circulation, heat-clearing and toxic substances removing.Dispelling the wind and dampness pathogens pain, contracture is numb, carbuncle, traumatic injury, enteritis, dysentery.
Caulis Lonicerae: base is former: be the stem and leaf of caprifoliaceae plant Radix Ophiopogonis.Chemical analysis: leaf is containing the flavonoid such as lonicerin and luteolin-7-scillabiose, luteolin.Stem is containing tannin, alkaloid.Pharmacological action: luteolin has spasmolysis to smooth muscle (rabbit residence body small intestinal), but not as good as papaverine; And have mild diuretic (increasing the discharge of sodium chloride) effect.Nature and flavor: sweet, cold.Gui Jing: enter the heart, lung meridian.Function cures mainly: heat clearing away, removing toxic substances, dredging collateral.Control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.
Zhu's lip: base is former: be the herb of Lamiaceae Salvia platymiscium Zhu lip.Pharmacological action: resisting oxygen lack.The property of medicine: pungent, micro-hardship, puckery, cool.Gui Jing: liver, spleen channel.Cure mainly: metrorrhagia; High heat; Stomachache is uncomfortable.
Radix seu Caulis fici Martinii grass: base is former: be rattan and the leaf of the blunt calyx Radix clematidis floridae of ranunculaceae plant.Chemical analysis: containing Anemonin.Nature and flavor: bitter in the mouth; Bitter; Cool in nature.Gui Jing: lung, spleen channel.Function cures mainly: expelling wind and clearing away heat; With network pain relieving.Main rheumatic arthritis; Rubella pruritus; Skin ulcer scabies; Toxic swelling; Acute catarrhal conjunctivitis pain; And dysuria.
Crow bone fiber crops: base is former: be rhizome and the herb of contrayerva Mount Lushan Zlatostema involucratum Franch. Et savat..Nature and flavor: bitter; Pungent; Warm in nature.Function cures mainly: blood circulation promoting and blood stasis dispelling; Removing toxic substances and promoting subsidence of swelling; Cough-relieving.Main osteopatia sprain; Fracture; Amenorrhea; Rheumatic arthralgia; Mumps; Herpes zoster; Skin ulcer swells; Venom; Cough.
Caulis Periplocae Calophyllae: base is former: be the stem of the blue or green mabi of Asclepiadaceae plant.Nature and flavor: " Traditional Chinese Medicine in Sichuan will ": " the micro-hardship of acrid in the mouth, hot in nature." function cures mainly: 1. " classify herbal ": " walk to show cold expelling, control lumbago, go wind to fall apart blood." 2. " Traditional Chinese Medicine in Sichuan will ": " controls lumbago, rheumatic numbness, traumatic injury, venom."
Niu Teng: base is former: be stem and the root of that rattan of Lardizabalaceae Caulis et folium stauntoniae platymiscium or that rattan of leaf tail, the property of medicine: bitter, cool, function cures mainly: dispel the wind dissipating blood stasis, pain relieving, inducing diuresis to remove edema.Cure mainly rheumatic arthralgia, traumatic pain, various neuropathic pain, dysuria, edema.
Fructus Lauri nobilis: base is former: be the fruit of Lauraceae bay Laurel.Composition: fruit, containing volatile oil, inside has myrcene lactone, costunolide etc.Oil-containing 38.9% again, wherein fatty acid mainly contains: Palmic acid 39.5%, hexadecenoic acid 0.5%, stearic acid 0.4%, oleic acid 31.4% etc.The property of medicine: pungent, temperature, nontoxic.Function cures mainly: expelling wind and removing dampness, removing toxic substances, parasite killing.Cure mainly rheumatic arthralgia, fugu poisoning, scabies, right retroauricular carbuncle.
embodiment 1the medicament for the treatment of rheumatic lumbar vertebra sufferer, is prepared from by following bulk drugs, is weight portion (50g/ part): Rhizoma Polygonati 15 parts; 10 parts, cattle rattan; Herba Epimedii 15 parts; The Cortex Eucommiae 15 parts; Herba Begoniae Laciniatae 9 parts; Fructus Rubi 9 parts; Geranium 9 parts; Fructus Lauri nobilis 8 parts; Caulis Lonicerae 7 parts; 8 parts, Zhu's lip; Radix seu Caulis fici Martinii grass 9 parts; Crow bone fiber crops 7 parts; Caulis Periplocae Calophyllae 8 parts.
The preparation method of the decoction of above-mentioned treatment rheumatic lumbar vertebra sufferer is:
(1) Rhizoma Polygonati section, gets muscovado and adds water and dissolve (medical material muscovado per jin 3 liang), be sprinkled in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, for subsequent use;
(2) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 100kg, with refining Adeps caprae seu ovis 20kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 100kg Cortex Eucommiae Sal 2kg);
(3) medical material after being processed step (1)-(2) and cattle rattan, Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Caulis Lonicerae, Zhu's lip, Radix seu Caulis fici Martinii grass, black bone fiber crops and Caulis Periplocae Calophyllae are together placed in non iron container, add pure water and the yellow wine (ratio of pure water and yellow wine is 8:1) of 6 times amount, soak 3 hours, intense fire boils, turn slow fire boiling 1 hour, filter, obtain decocting liquid;
(4) cooled by above-mentioned decocting liquid, 115 DEG C of sterilizings 1.5 hours, encapsulation, to obtain final product.
The instructions of taking of decoction of the present invention is: once a day, each 200-300mL, 7 days courses for the treatment of.
Model case: Lee XX, man, 41 years old, people from Zhengzhou.On February 5th, 2010 is to our hospital.Patient's readme: suffer from rheumatic lumbago and have a surplus half a year, when showing effect, hurt like hell, can not be upright at every turn, run into blowing and raining, pain is obviously aggravated, once acupuncture and moxibustion therapy, and curative effect is undesirable, paste SHANGSHI ZHITONG GAO to alleviate, before three days, pain increases the weight of always, introduces my institute's treatment good friend.
Take the decoction of the present embodiment gained treatment rheumatic lumbar vertebra sufferer, instructions of taking: once a day, each 200-300mL, 7 days courses for the treatment of.After treating a course for the treatment of, patient's lumbago symptom obviously alleviates, and continues two courses for the treatment of of medication, and patient pain disappears, and waist can straighten, and patient's self-induction is fully recovered, and follows up a case by regular visits to after half a year, without recurrence.
embodiment 2the medicament for the treatment of rheumatic lumbar vertebra sufferer, is prepared from by following bulk drugs, is weight portion (30g/ part): Rhizoma Polygonati 30 parts; 15 parts, cattle rattan; Herba Epimedii 20 parts; The Cortex Eucommiae 25 parts; Herba Begoniae Laciniatae 12 parts; Fructus Rubi 15 parts; Geranium 16 parts; Fructus Lauri nobilis 16 parts; Caulis Lonicerae 14 parts; 12 parts, Zhu's lip; Radix seu Caulis fici Martinii grass 16 parts; Crow bone fiber crops 15 parts; Caulis Periplocae Calophyllae 12 parts.
The preparation method of the pill of above-mentioned treatment rheumatic lumbar vertebra sufferer is:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) by gained fine medicinal material powder mixing in step (1), 100 mesh sieves are crossed, for subsequent use;
(3) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 10kg, with refining Adeps caprae seu ovis 2kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 10kg Cortex Eucommiae Sal 0.2kg);
(4) Herba Epimedii silk step (3) processed and the Cortex Eucommiae and Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are together placed in non iron container, add the pure water of 7 times amount, soak 2.5 hours, intense fire boils, turn slow fire boiling 1.2 hours, filter, obtain decocting liquid;
(5) above-mentioned gained decocting liquid is carried out distilling under reduced pressure, be condensed into paste, add step (2) gained fine powder, stir, make pill according to the processing method of pill, to obtain final product.
The instructions of taking of pill of the present invention is: every day 3 times, each 4-6 ball, 7 days courses for the treatment of.
Model case a: XX, female, 67 years old, in July, 2010 was to our hospital.Patient's readme: suffer from rheumatic lumbago 1 year, symptom is: lumbago, and waist is sent out heavy, after tired or overcast and rainyly to increase the weight of, takes a turn for the better when fine day or warmer climate, can not sitting for a long time; Fatiguability is weak, and whole body is listless and aching heavy, and affected part is afraid of cold, pale tongue.Patient once carried out massage treatment at local hospital, recurred soon after treatment, existing aggravation, under the leading of layman, carried out my institute's treatment.
Take the pill of the present embodiment gained treatment rheumatic lumbar vertebra sufferer, instructions of taking: every day 3 times, each 4-6 ball, 7 days courses for the treatment of.After taking two courses for the treatment of, patient's lumbago symptom obviously alleviates, and continues a course for the treatment of of medication, and patient can free sitting, and fear of cold transference cure, lumbago symptom is eliminated, and patient's self-induction is fully recovered, physical recovery.
embodiment 3the medicament for the treatment of rheumatic lumbar vertebra sufferer, is prepared from by following bulk drugs, is weight portion (45g/ part): Rhizoma Polygonati 20 parts; 11 parts, cattle rattan; Herba Epimedii 16 parts; The Cortex Eucommiae 18 parts; Herba Begoniae Laciniatae 10 parts; Fructus Rubi 11 parts; Geranium 11 parts; Fructus Lauri nobilis 10 parts; Caulis Lonicerae 9 parts; 9 parts, Zhu's lip; Radix seu Caulis fici Martinii grass 11 parts; Crow bone fiber crops 10 parts; Caulis Periplocae Calophyllae 9 parts.
The preparation method of the capsule of above-mentioned treatment rheumatic lumbar vertebra sufferer is:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) get butter, put slow fire heat fused in pot, more above-mentioned Herba Epimedii silk is poured into, fry and mix evenly, take out, spread out, dry in the air cool, smash into powder (every Herba Epimedii 100kg, uses butter 25kg) for subsequent use to pieces; The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip, pulverizes;
(3) by gained fine medicinal material powder mixing in step (1)-(2), 150 mesh sieves are crossed, for subsequent use;
(4) Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are together placed in crock, add 35 DEG C of pure water and do not have powder, soak 3 hours, then intense fire boils, fire heating decoction twice of larding speech with literary allusions, first time decocts 50 minutes, second time decocts 35 minutes, in decoction process, keeps water not have powder 2-3cm, filter, merge twice decocting liquid;
(5) above-mentioned decocting liquid being evaporated to 70 DEG C of proportions is the extractum of 1.19-1.32, add step (3) gained fine powder, stir, add cane sugar powder, corn starch and calcium hydrogen phosphate (extract powder: cane sugar powder: corn starch: calcium hydrogen phosphate is 7:1.3: 1.1: 1.4), wet granulation, cross 80 mesh sieves, packaging, to obtain final product.
The instructions of taking of capsule of the present invention is: every day 3 times, each 4-6 grain, 7 days courses for the treatment of.
Model case: grandson XX, man, 45 years old, in July, 2011 was to our hospital.Patient's readme: aching pain in waist and back, limitation of activity, coughs or when talking and laugh loudly, flank pain aggravates, and can not oneself get up after lying down.Once by SHANGSHI ZHITONG GAO all without obvious curative effects.Carry out my institute's treatment after being introduced.Check: patient's lumbago and skelalgia, right lower extremity is numb, and waist is stiff, fear of cold, dimly red tongue, thin white fur of tongue, hesitant pulse.Be diagnosed as prolapse of lumbar intervertebral disc.
Take the capsule of the present embodiment gained treatment rheumatic lumbar vertebra sufferer, instructions of taking: every day 3 times, each 4-6 grain, 7 days courses for the treatment of.After taking a course for the treatment of, lumbago and skelalgia symptom is alleviated greatly, and right lower extremity numbness alleviates, and continues two courses for the treatment of of medication, and patient's malaise symptoms disappears, and self-induction is fully recovered.So far without recurrence.
embodiment 4the medicament for the treatment of rheumatic lumbar vertebra sufferer, is prepared from by following bulk drugs, is weight portion (35g/ part): Rhizoma Polygonati 25 parts; 14 parts, cattle rattan; Herba Epimedii 19 parts; The Cortex Eucommiae 22 parts; Herba Begoniae Laciniatae 11 parts; Fructus Rubi 13 parts; Geranium 14 parts; Fructus Lauri nobilis 14 parts; Caulis Lonicerae 12 parts; 11 parts, Zhu's lip; Radix seu Caulis fici Martinii grass 14 parts; Crow bone fiber crops 12 parts; Caulis Periplocae Calophyllae 11 parts.
The preparation method of the tablet of above-mentioned treatment rheumatic lumbar vertebra sufferer is:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) get butter, put slow fire heat fused in pot, more above-mentioned Herba Epimedii silk is poured into, fry and mix evenly, take out, spread out, dry in the air cool, smash into powder to pieces for subsequent use; The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip, pulverizes;
(3) Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are cleaned, dry 55 minutes, be placed in Chinese medicine grinder and be ground into fine powder for 70 DEG C;
(4) by step (1)-(3) gained fine powder mixing, stir, cross 110 mesh sieves, in mixing fine powders, add hypromellose, pregelatinized Starch and dextrin (medicated powder: hypromellose: pregelatinized Starch: dextrin is 9:1:0.8:0.7), make tablet, to obtain final product.
The instructions of taking of Tablets is: every day 3 times, each 3-5 sheet, 7 days courses for the treatment of.
Model case: Liu XX, female, 56 years old, in JIUYUE, 2011 was to our hospital.Patient's readme: suffer from prolapse of lumbar intervertebral disc 2 years, CT shows, and waist 5-sacrum 2 intercalated disc is given prominence to.Once ate Chinese medicine, Western medicine, did traction etc., therapeutic effect is undesirable.Carry out my institute's treatment after being introduced.Check: patient's lumbago is hard to bear, changes one's position unfavorable, meet cold rnning play, white and greasy fur, deep pulse is thought.Be diagnosed as the moist prolapse of lumbar intervertebral disc of wind and cold.
Take the tablet of the present embodiment gained treatment rheumatic lumbar vertebra sufferer, instructions of taking: every day 3 times, each 3-5 sheet, 7 days courses for the treatment of.After two courses for the treatment of of medication, patient's lumbago symptom alleviates, lower limb feeling relaxed, and continue a course for the treatment of of medication, patient fully recovers, so far without recurring.
embodiment 5the medicament for the treatment of rheumatic lumbar vertebra sufferer, is prepared from by following bulk drugs, is weight portion (40g/ part): Rhizoma Polygonati 22.5 parts; 12.5 parts, cattle rattan; Herba Epimedii 17.5 parts; The Cortex Eucommiae 20 parts; Herba Begoniae Laciniatae 10.5 parts; Fructus Rubi 12 parts; Geranium 12.5 parts; Fructus Lauri nobilis 12 parts; Caulis Lonicerae 10.5 parts; 10 parts, Zhu's lip; Radix seu Caulis fici Martinii grass 12.5 parts; Crow bone fiber crops 11 parts; Caulis Periplocae Calophyllae 10 parts.
The preparation method of the decoction of above-mentioned treatment rheumatic lumbar vertebra sufferer is:
(1) Rhizoma Polygonati section, gets muscovado and adds water and dissolve (medical material muscovado per jin 3 liang), be sprinkled in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, for subsequent use;
(2) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 100kg, with refining Adeps caprae seu ovis 20kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 100kg Cortex Eucommiae Sal 2kg);
(3) medical material after being processed step (1)-(2) and cattle rattan, Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Caulis Lonicerae, Zhu's lip, Radix seu Caulis fici Martinii grass, black bone fiber crops and Caulis Periplocae Calophyllae are together placed in non iron container, add pure water and the yellow wine (ratio of pure water and yellow wine is 8:1) of 8 times amount, soak 4.5 hours, intense fire boils, turn slow fire boiling 1.5 hours, filter, obtain decocting liquid;
(4) cooled by above-mentioned decocting liquid, 115 DEG C of sterilizings 2.5 hours, encapsulation, to obtain final product.
The instructions of taking of decoction of the present invention is: once a day, each 200-300mL, 7 days courses for the treatment of.
test example 1the clinical practice of the decoction (embodiment 5) of gained treatment rheumatic lumbar vertebra sufferer of the present invention:
1, data and method
1.1 physical data
In October ,-2013 in January, 2009, choose 269 routine rheumatic lumbar spondylosis patients of my institute's treatment.Wherein male patient 147 example, female patient 122 example; Oldest 72 years old, minimum 33 years old of age.
1.2 diagnostic criteria
All tcm diagnosis are that rheumatic lumbar spondylosis patient is as the object of observation.There is following symptom: joint of lumbar vertebra is ached, stiff, rotate inconvenience, rainy day pain increases the weight of, anemophobia cold, stiff lasting every day at least 1h, the course of disease is more than two months; X mating plate embodies prolapse of lumbar intervertebral disc, lumbar vertebra hyperosteogeny, lumbar spinal stenosis etc.
1.3 Therapeutic Method
All patients are divided into two groups at random, experimental group and matched group, and experimental group takes products obtained therefrom of the present invention, and instructions of taking is: once a day, each 200-300mL, 7 days courses for the treatment of.Matched group takes other medicine (as capsules for curing waist pain, snow mountain Chinese medicine Zhuifengsan, Moschus are dispelled the conventional medication such as pain liniment).Observe two courses for the treatment of of treatment altogether.
1.4 efficacy assessment standard
Cure: lumbago and skelalgia transference cure, spinal column waist is movable normal, can normally work.Effective: lumbago and skelalgia symptom partial disappearance, spinal column is movable normal, and waist function is improved; Effective: lumbago and skelalgia symptom alleviates; Invalid: symptom, sign are without improvement.
Total effective rate=(cure number of cases+effective number of cases+effectively number of cases) ∕ total inspection case load × 100%.
1.5 therapeutic outcome
Therapeutic outcome is as shown in table 1:
Table 1: take product 33-72 of the present invention year rheumatic lumbar spondylosis patient treatment outcome
Therapeutic effect: cure 93 examples (62%), effective 36 examples (24%), effective 19 examples (12.7%); Invalid 2 examples (1.3%), total effective rate 98.7%.Successful is better than matched group.
The present invention select Rhizoma Polygonati, Niu Teng, Herba Epimedii, the Cortex Eucommiae, Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Caulis Lonicerae, Zhu's lip, Radix seu Caulis fici Martinii grass, black bone fiber crops and Caulis Periplocae Calophyllae totally 13 taste Chinese herbal medicine combine.Fang Zhong, Rhizoma Polygonati has invigorating the spleen and replenishing QI, profit cardiopulmonary, the effect of bone and muscle strengthening; Herba Epimedii kidney invigorating and YANG supporting, expelling wind and removing dampness; The Cortex Eucommiae is used for lumbago due to renal deficiency, and muscles and bones is unable; Herba Begoniae Laciniatae cures mainly cold cough, rheumatic ostalgia, lumbago; Fructus Rubi invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight; Geranium dispels the wind, and invigorates blood circulation, heat-clearing and toxic substances removing.Dispelling the wind and dampness pathogens pain, contracture is numb; Caulis Lonicerae has heat clearing away, removing toxic substances, effect of dredging collateral; Zhu's lip cures mainly metrorrhagia, high heat, and stomachache is uncomfortable; Radix seu Caulis fici Martinii grass cures mainly rheumatic arthritis; Crow bone fiber crops have significant curative effect to osteopatia sprain, fracture, amenorrhea, rheumatic arthralgia.Full side's compatibility, plays the dissipating blood stasis that dispels the wind altogether, the merit of pain relieving, treats various rheumatism numbness and leads to.Treat two courses for the treatment of, effective percentage can reach 98.7%, and matched group is only 78.2%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the medicament of rheumatic lumbar vertebra sufferer, it is characterized in that, be prepared from by following bulk drugs, be weight portion: Rhizoma Polygonati 15-30; Cattle rattan 10-15; Herba Epimedii 15-20; Cortex Eucommiae 15-25; Herba Begoniae Laciniatae 9-12; Fructus Rubi 9-15; Geranium 9-16; Fructus Lauri nobilis 8-16; Caulis Lonicerae 7-14; Zhu's lip 8-12; Radix seu Caulis fici Martinii grass 9-16; Crow bone fiber crops 7-15; Caulis Periplocae Calophyllae 8-12.
2. the medicament for the treatment of rheumatic lumbar vertebra sufferer as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Rhizoma Polygonati 20-25; Cattle rattan 11-14; Herba Epimedii 16-19; Cortex Eucommiae 18-22; Herba Begoniae Laciniatae 10-11; Fructus Rubi 11-13; Geranium 11-14; Fructus Lauri nobilis 10-14; Caulis Lonicerae 9-12; Zhu's lip 9-11; Radix seu Caulis fici Martinii grass 11-14; Crow bone fiber crops 10-12; Caulis Periplocae Calophyllae 9-11.
3. the medicament for the treatment of rheumatic lumbar vertebra sufferer as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Rhizoma Polygonati 22.5; Cattle rattan 12.5; Herba Epimedii 17.5; The Cortex Eucommiae 20; Herba Begoniae Laciniatae 10.5; Fructus Rubi 12; Geranium 12.5; Fructus Lauri nobilis 12; Caulis Lonicerae 10.5; Zhu's lip 10; Radix seu Caulis fici Martinii grass 12.5; Crow bone fiber crops 11; Caulis Periplocae Calophyllae 10.
4. the medicament of the treatment rheumatic lumbar vertebra sufferer as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable decoction, preparation method is as follows:
(1) Rhizoma Polygonati section, gets muscovado and adds water and dissolve (medical material muscovado per jin 3 liang), be sprinkled in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, for subsequent use;
(2) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 100kg, with refining Adeps caprae seu ovis 20kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 100kg Cortex Eucommiae Sal 2kg);
(3) medical material after being processed step (1)-(2) and cattle rattan, Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Caulis Lonicerae, Zhu's lip, Radix seu Caulis fici Martinii grass, black bone fiber crops and Caulis Periplocae Calophyllae are together placed in non iron container, add pure water and the yellow wine of 6-10 times amount, soak 3-6 hour (preferably soaking 4-5 hour), intense fire boils, turn slow fire boiling 1-2 hour (preferably decocting 1.5 hours), filter, obtain decocting liquid;
(4) cooled by above-mentioned decocting liquid, 115 DEG C of sterilizings, encapsulation, to obtain final product.
5. as claimed in claim 4 decoction preparation method, it is characterized in that, the ratio of pure water and yellow wine is 8:1 in step (3).
6. as claimed in claim 4 decoction preparation method, it is characterized in that, sterilization time is 1.5-3.5 hour (preferred sterilization time is 2-3 hour, and the sterilization time be more preferably is 2.5 hours) in step (4).
7. the medicament of the treatment rheumatic lumbar vertebra sufferer as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable pill, preparation method is as follows:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) by gained fine medicinal material powder mixing in step (1), sieve for subsequent use;
(3) get Adeps caprae seu ovis heat fused, add Herba Epimedii silk, fry to evenly glossy with slow fire, take out, cool (every Herba Epimedii 10kg, with refining Adeps caprae seu ovis 2kg); The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip (every 10kg Cortex Eucommiae Sal 0.2kg);
(4) Herba Epimedii silk step (3) processed and the Cortex Eucommiae and Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are together placed in non iron container, add the pure water of 5-9 times amount, soak 2-3 hour (preferably soaking 2.5 hours), intense fire boils, turn slow fire boiling 0.8-1.5 hour (preferably decocting 1.2 hours), filter, obtain decocting liquid;
(5) above-mentioned gained decocting liquid is carried out distilling under reduced pressure, be condensed into paste, add step (2) gained fine powder, stir, make pill according to the processing method of pill, to obtain final product.
8. as claimed in claim 7 pill preparation method, it is characterized in that, cross 80-120 mesh sieve (preferred cross 90-110 mesh sieve, mistake 100 mesh sieve be more preferably) in step (2).
9. the medicament of the treatment rheumatic lumbar vertebra sufferer as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable capsule, preparation method is as follows:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) get butter, put slow fire heat fused in pot, more above-mentioned Herba Epimedii silk is poured into, fry and mix evenly, take out, spread out, dry in the air cool, smash into powder (every Herba Epimedii 100kg, uses butter 25kg) for subsequent use to pieces; The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip, pulverizes;
(3) by gained fine medicinal material powder mixing in step (1)-(2), 120-180 mesh sieve (preferred mistake 150 mesh sieve) is crossed, for subsequent use;
(4) Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are together placed in crock, add 30-40 DEG C of pure water and do not have powder (preferably add 35 DEG C of pure water and do not have powder), soak 2-4 hour (preferably soaking 3 hours), then intense fire boils, fire of larding speech with literary allusions heats decoction twice, first time decocts 40-60 minute (preferably first time decocts 50 minutes), second time decocts 25-45 minute (preferably second time decocts 35 minutes), in decoction process, water is kept not have powder 2-3cm, filter, merge twice decocting liquid;
(5) above-mentioned decocting liquid being evaporated to 70 DEG C of proportions is the extractum of 1.19-1.32, add step (3) gained fine powder, stir, add cane sugar powder, corn starch and calcium hydrogen phosphate (extract powder: cane sugar powder: corn starch: calcium hydrogen phosphate is 7:1.3:1.1:1.4), wet granulation, cross 80 mesh sieves, packaging, to obtain final product.
10. the medicament of the treatment rheumatic lumbar vertebra sufferer as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable tablet, preparation method is as follows:
(1) Rhizoma Polygonati section, gets Mel and adds water and dissolve (medical material Mel per jin 6 liang), pour in Rhizoma Polygonati sheet, mix thoroughly, takes out after exhausting, and puts in food steamer to steam to rise latter 1 hour to Primordial Qi, and taking-up is dried, and grinds for subsequent use; Getting Caulis Lonicerae, Niu Teng, Caulis Periplocae Calophyllae and Radix seu Caulis fici Martinii grass pours in basin, mixes thoroughly, put in tank with decoction of black soybean and yellow wine, sealing, sits stewing out of water in kettle and exhausts to juice, take out, dry, grind into powder for subsequent use;
(2) get butter, put slow fire heat fused in pot, more above-mentioned Herba Epimedii silk is poured into, fry and mix evenly, take out, spread out, dry in the air cool, smash into powder to pieces for subsequent use; The Cortex Eucommiae is cleaned, and stripping and slicing, adds saline and mix thoroughly, slightly vexed, after saline is sucked, puts in the parch container of preheating appropriateness, fries to surface coke black with moderate heat, and when silk is easily broken, taking-up is dried in the air cool, and sieve removes chip, pulverizes;
(3) Herba Begoniae Laciniatae, Fructus Rubi, geranium, Fructus Lauri nobilis, Zhu's lip and black bone fiber crops are cleaned, dry 45-65 minute (preferably drying 55 minutes for 70 DEG C), be placed in Chinese medicine grinder and be ground into fine powder for 70 DEG C;
(4) by step (1)-(3) gained fine powder mixing, stir, cross 90-130 mesh sieve (preferred mistake 110 mesh sieve), hypromellose, pregelatinized Starch and dextrin (medicated powder: hypromellose: pregelatinized Starch: dextrin is 9:1:0.8:0.7) is added in mixing fine powders, make tablet, to obtain final product.
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| CN105412178A (en) * | 2016-01-22 | 2016-03-23 | 俞宏发 | Traditional Chinese medicine composition for treating rheumatic lumbar disease as well as preparation method and application |
| CN106261618A (en) * | 2016-08-16 | 2017-01-04 | 湖南大湘西魔芋有限公司 | A kind of Rhizoma Polygonati face and production method thereof |
| CN106474397A (en) * | 2015-11-28 | 2017-03-08 | 衡阳春天医药化工设备有限公司 | A kind of Chinese medicine for treating lumbar spine pain and preparation method thereof |
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| CN105412178A (en) * | 2016-01-22 | 2016-03-23 | 俞宏发 | Traditional Chinese medicine composition for treating rheumatic lumbar disease as well as preparation method and application |
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