CN104042673A - Traditional Chinese medicinal capsule for treating hypertension and preparation method thereof - Google Patents

Traditional Chinese medicinal capsule for treating hypertension and preparation method thereof Download PDF

Info

Publication number
CN104042673A
CN104042673A CN201410322791.XA CN201410322791A CN104042673A CN 104042673 A CN104042673 A CN 104042673A CN 201410322791 A CN201410322791 A CN 201410322791A CN 104042673 A CN104042673 A CN 104042673A
Authority
CN
China
Prior art keywords
parts
radix
chinese medicinal
herba
medicinal capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201410322791.XA
Other languages
Chinese (zh)
Other versions
CN104042673B (en
Inventor
张家能
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ningbo Pubinfo Industry Co., Ltd.
Original Assignee
张家能
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 张家能 filed Critical 张家能
Priority to CN201410322791.XA priority Critical patent/CN104042673B/en
Publication of CN104042673A publication Critical patent/CN104042673A/en
Application granted granted Critical
Publication of CN104042673B publication Critical patent/CN104042673B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention discloses a traditional Chinese medicinal capsule for treating hypertension and a preparation method thereof. The traditional Chinese medicinal capsule for treating the hypertension is mainly prepared from the following raw materials: selfheal, root of kudzu wine, radix bupleuri, bark of eucommia, herba taxilli and astragalus membranaceus, and the raw materials such as herba siegesbeckiae, szechuan lovage rhizome, root of bidentate achyranthes, salvia miltiorrhiza, polygonum cuspidatum, yang tonifying herb, lysimachia christinae hance, coix seed, medlar, white paeony root, cassia seed, oriental wormwood, lophatherum gracile, root-bark of tree peony and liquorice can be added, so that treatment effect can be better, and a specific technology is adopted for processing, so that the traditional Chinese medicinal capsule for treating the hypertension is obtained, curative effect of the traditional Chinese medicinal capsule for treating the hypertension is good, absorption and regulation abilities of the middle-aged and aged people can be enhanced, and curative ratio is more than 90%.

Description

A kind of hypertensive Chinese medicinal capsule and preparation method thereof for the treatment of
Technical field
The present invention relates to Chinese medicinal composition capsules, be specifically related to a kind of hypertensive Chinese medicinal capsule and preparation method thereof for the treatment of.
Background technology
Hypertension is commonly encountered diseases, frequently-occurring disease, has become " the noiseless killer " that affect human health and life.Hypertension sickness rate in elderly population is very high, and often causes the infringement of a plurality of organs such as the heart, brain, kidney, blood vessel, reduces life quality, and severe patient can life-threatening.The reason that hypertension produces is because endovascular obstruction causes, and heart propelling movement blood causes the systolic pressure of heart and diastolic pressure to occur the phenomenon increasing to the pressure increase of blood vessel.General Influence is hypertensive because have diet, motion, mood etc., according to the Li Shizhen (1518-1593 A.D.) < < of Ming Dynasty Compendium of Materia Medica > > the 9th volume, record that " Gypsum Fibrosum also claims thin Gypsum Fibrosum; have another name called " Mirabilitum crystallina "; cure mainly apoplexy cold and heat; have expelling pathogenic factors from muscles by diaphoresis; except xerostomia scorching tongue, and the headache function such as have a toothache, is the antipyretic good medicine of pestilence of dispelling." Chinese people, make medicated pillow for a long time with the plaster of paris, Xue Tang Dynasty has met poem < < gypsum pillow > >, and " the well-illuminated not false carving of the exterior and the interior, is cooler than spring snow Bai Yuyao.Towards sending on bamboo couch, the wind sunburn pin of being only afraid of." according to theory of Chinese medical science and use among the people, proving: hypertension belongs to heat symptom-complex; Gypsum Fibrosum is cold in nature; with Gypsum Fibrosum, grind and form Gao Lao village Gypsum Fibrosum blood pressure-reducing pillow; to tremble with fear, gram heat energy regulates cranial nerve and human brain normal temperature naturally; cerebrovascular is normally worked; can effectively control hypertension, adheres to for a long time using, and blood pressure progressively can be reduced to normal level.But at this, develop rapidly in society, depend merely on this with gram hot external method effect not obvious of trembling with fear, and speed is also slower, we need a kind of energy capsule for oral administration, are beneficial to absorption, constantly regulate physiological equilibrium, finally keep the normal level of blood pressure.
The traditional Chinese medical science thinks that primary disease is due to damaged by excess of seven emotions, intemperance of taking food, and internal injury is deficient to be caused, with the heart, spleen, liver, kidney, dirty in close relations, common excessive rising of liver-YANG, phlegm-damp resistance network, qi depression to blood stasis, the hepatic and renal YIN deficiency, hyperactivity of hesrt-fire and liver-fire, need that research preparation is a kind of can regulate the heart, spleen, liver, kidney, dirty physiological function comprehensively, improve autoimmunity, dredge the meridian passage, maintain the equilibrium between yin and yang of body, realize the oral Chinese medicine capsule of the blood pressure normal level of human body.
Summary of the invention
In order to solve the technical problem in background technology, the invention provides a kind of hypertensive Chinese medicinal capsule and preparation method thereof for the treatment of, the raw material weight component that the preparation of this Chinese medicinal capsule is used comprises: Spica Prunellae 15-20 part, Radix Puerariae 10-15 part, Radix Bupleuri 13-17 part, Cortex Eucommiae 15-20 part, parasitic 10-14 part, Radix Astragali 6-10 part.
Preferably, the raw material weight component of making described Chinese medicinal capsule also comprises: Herba Siegesbeckiae 12-15 part, Rhizoma Chuanxiong 9-13 part, Radix Achyranthis Bidentatae 15-20 part, Radix Salviae Miltiorrhizae 6-8 part, Rhizoma Polygoni Cuspidati 8-10 part, Folium Allii tuberosi 6-8 part, Herba Lysimachiae 5-7 part, Semen Coicis 12-17 part, Fructus Lycii 10-15 part, Radix Paeoniae Alba 5-7 part, Semen Cassiae 15-20 part, Artemisia anethoicles Mattf 3-5 part, Herba Lophatheri 3-5 part, Cortex Moutan 10-15 part, Radix Glycyrrhizae 2-3 part.
Preferably, described Chinese medicinal capsule is made by the raw material of following components by weight percent: 2 parts, 17 parts of Spica Prunellaes, 12 parts of Radix Puerariaes, 15 parts of Radix Bupleuri, 16 parts of the Cortexs Eucommiae, parasitic 12 parts, the Radix Astragali 7 13 parts of Fen, Herba Siegesbeckiaes, 12 parts of Rhizoma Chuanxiongs, 16 parts of Radix Achyranthis Bidentataes, 7 parts of Radix Salviae Miltiorrhizaes, 9 parts of Rhizoma Polygoni Cuspidati, 7 parts of Folium Allii tuberosi, 6 parts of Herba Lysimachiaes, 15 parts of Semen Coiciss, 13 parts of Fructus Lyciis, 7 parts of the Radix Paeoniae Albas, 18 parts of Semen Cassiaes, 5 parts of Artemisia anethoicles Mattf, 4 parts of Herba Lophatheris, 15 parts of Cortex Moutans and Radix Glycyrrhizae.
Preferably, described Chinese medicinal capsule is made by the raw material of following components by weight percent: 7 parts of 17 parts of Spica Prunellaes, 12 parts of Radix Puerariaes, 15 parts of Radix Bupleuri, 16 parts of the Cortexs Eucommiae, parasitic 12 parts and the Radixs Astragali.
Spica Prunellae is cold in nature, sweet in the mouth, pungent, micro-hardship, there is the effect of letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis, be applicable to lymphoid tuberculosis, goiter, acute mastitis, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, metrorrhagia, leukorrhagia, Fiedeler's disease type hepatitis and bacillary dysentery etc.Modern pharmacological research shows, Spica Prunellae has the effect reducing blood pressure, and can blood vessel dilating, and its contained rutin has antiinflammatory action, and can reduce vascular permeability, reduces fragility, reduces liver fat.Spica Prunellae resists the effect of cancerous cell in addition.Radix Puerariae has certain antitumaous effect, has the effect of obvious induced tumor necrosin, and cisplatin is had to synergism and attenuation, reduces serum cholesterol and contains.That Radix Bupleuri has is antipyretic, the effect of antiinflammatory, Promote immunity function, anti-liver injury, Antiradiation injury.The Cortex Eucommiae is warm in nature, sweet in the mouth, there is invigorating the liver and kidney, strong waist knee joint, bone and muscle strengthening, antiabortive effect, and the Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system, the excited hypophysis of Cortex Eucommiae energy, interrenal system, adrenal cortex reinforcing function.Parasitic bitter in the mouth and sweet, property is flat, returns liver and kidney, and major function is for controlling invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive.Radix Astragali sweet in the mouth, slightly warm in nature, returns lung, spleen, liver, kidney channel, coordinates different Chinese medicine ingredients to bring into play different medical values.Herba Siegesbeckiae is mainly used in that rheumatic arthritis, muscles and bones are unable, soreness of the waist and knees, quadriplegia, hemiplegia, rubella eczema, coordinates material composition of the present invention, can bring into play maximum blood pressure lowering and vasorelaxation action.Rhizoma Chuanxiong energy coronary artery dilator, increases coronary artery blood flow, improves myocardium blood oxygen supply, and reduces myocardium oxygen consumption, and expansible cerebrovascular, reduces vascular resistance, significantly increases brain and LBF amount, improves microcirculation.Radix Achyranthis Bidentatae bitter in the mouth and acid, property is flat, enters liver, kidney channel, eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.Radix Salviae Miltiorrhizae bitter in the mouth, cold nature, can blood circulation promoting and blood stasis dispelling, removing heat from blood, calms the nerves, coronary artery dilator, improve myocardial ischemia situation, with all worries set aside, blood sugar lowering and the effect such as antibacterial reduce blood pressure, calm the nerves.The micro-hardship of Rhizoma Polygoni Cuspidati, cold nature, returns liver, gallbladder, lung meridian, dispels the wind, dampness removing, removing blood stasis with potent drugs, stimulates the menstrual flow.Folium Allii tuberosi has another name called Folium Allii tuberosi, warm in nature, acrid in the mouth, the liver benefiting stomach invigorating, circulation of qi promoting treating blood disorders, loosening bowel to relieve constipation.Herba Lysimachiae has calculus, function of gallbladder promoting, inhibition thrombosis, improves the effect of immunity, has the merit of clearing away heat and promoting diuresis, wind-expelling pain-stopping, hemostasia and promoting granulation, eliminating inflammation and expelling toxin, parasite killing.Semen Coicis has spleen invigorating eliminating dampness by diuresis, and eliminating impediment antidiarrheal, for the effect of edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.Fructus Lycii is flat, sweet in the mouth, nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat quench one's thirst, blood deficiency and yellow complexion, blurred vision be not clear.The Radix Paeoniae Alba has invigorating qi and benefiting blood, nourishes conditioning vim and vigour for human body, and liver's asthenic fire is calmed down by dredging people's liver, and analgesic antiphlogistic, has therapeutical effect well to the cloudy gas of human body especially women.Semen Cassiae bitter in the mouth, cold nature, the function of tool clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Raw Semen Cassiae is longer than removing heat from the liver, and intestine moistening is dry.For conjunctival congestion and swelling pain, constipation.Artemisia anethoicles Mattf mildly bitter flavor and micro-pungent, cold nature, returns spleen, stomach, urinary bladder channel, has remarkable choleretic effect, and have antipyretic, protect the liver, antitumor and hypotensive effect.Herba Lophatheri property slightly sweet flavor, can clear away heart-fire, diuresis, the agitation of dispelling, and for gingival swelling and pain, stomatitis etc., has good curative effect.Cortex Moutan has increase coronary flow, reduces cardiac output, reduces the effect of left chamber work done, clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Radix Glycyrrhizae sweet in the mouth, property is flat, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Raw material of the present invention comprises Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitic, the interaction that Radix Astragali combination just can be passed through the effective ingredient of this raw material realizes hypertension, hyperlipidemia, the treatment of hyperglycemic patients, and make better to recover the normal level of blood pressure and regulate blood glucose balance, the effectively generation of prevention of arterial sclerosis and cardiovascular and cerebrovascular disease again, the all right Zeng Jia Herba Siegesbeckiae of the present invention, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan, the raw materials such as Radix Glycyrrhizae together compound action are realized adjust blood pressure hypotensive effect better faster, regulate the physiological function of health.
Adopt raw material components to comprise that Spica Prunellae 15-20 part, Radix Puerariae 10-15 part, Radix Bupleuri 13-17 part, Cortex Eucommiae 15-20 part, parasitic 10-14 part, Radix Astragali 6-10 part prepares the method for this Chinese medicinal capsule, comprise the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 5-6 minute, the Cortex Eucommiae is put in the saline of 5-7% concentration soaks after 8-10 minute and salvages and dry, and then sends into together and in pulverizer, after co-grinding 10-15 minute, crosses 100-200 mesh sieve;
(2) add 80-100 part pure water to stir in ground product, adjust PH to 6.0-6.4, steam 20-25 minute;
(3) send into grinding machine for grinding and cross 600-800 mesh sieve;
(4) decoct and fry to yellow, then cure 5-8 minute, keep the moisture of 5-6% and evenly spray the molasses of 0.5-1.0%, obtain powders A;
(5) powders A is incapsulated after ultraviolet disinfection in shell, the dose of each capsule is 0.5g;
(6) capsule is packed through cobalt radiation sterilization final vacuum.
Adopting raw material components is the method that Spica Prunellae 15-20 part, Radix Puerariae 10-15 part, Radix Bupleuri 13-17 part, Cortex Eucommiae 15-20 part, parasitic 10-14 part, Radix Astragali 6-10 Fen, Herba Siegesbeckiae 12-15 part, Rhizoma Chuanxiong 9-13 part, Radix Achyranthis Bidentatae 15-20 part, Radix Salviae Miltiorrhizae 6-8 part, Rhizoma Polygoni Cuspidati 8-10 part, Folium Allii tuberosi 6-8 part, Herba Lysimachiae 5-7 part, Semen Coicis 12-17 part, Fructus Lycii 10-15 part, Radix Paeoniae Alba 5-7 part, Semen Cassiae 15-20 part, Artemisia anethoicles Mattf 3-5 part, Herba Lophatheri 3-5 part, Cortex Moutan 10-15 part, Radix Glycyrrhizae 2-3 part are prepared this Chinese medicinal capsule, comprises the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 5-6 minute, the Cortex Eucommiae is put in the saline of 5-7% concentration soaks after 8-10 minute and salvages and dry, and then sends into together and in pulverizer, after co-grinding 10-15 minute, crosses 100-200 mesh sieve;
(2) add 80-100 part pure water to stir in ground product, adjust PH to 6.0-6.4, steam 20-25 minute;
(3) send into grinding machine for grinding and cross 600-800 mesh sieve;
(4) decoct and fry to yellow, then cure 5-8 minute, keep the moisture of 5-6% and evenly spray the molasses of 0.5-1.0%, obtain powders A;
(5) clean Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae to dry; Then Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae are pulverized respectively and cross 100-200 mesh sieve after add pure water 100-120 part mix and blend to decoct after 10-15 minute to grind 600-800 mesh sieve and dried to obtain powder B;
(6) described powders A and powder B mix homogeneously are incapsulated in shell after ultraviolet disinfection, the dose of each capsule is 0.5g;
(7) capsule is packed through cobalt radiation sterilization final vacuum.
Beneficial effect of the present invention: the present invention adopts natural Chinese medicines composition, and pass through the reasonably combined of each effective ingredient, and obtain Chinese medicinal capsule of the present invention through specific processes, make this Chinese medicinal capsule good effect, can regulate the heart comprehensively, spleen, liver, kidney, dirty physiological function, improve autoimmunity, dredge the meridian passage, maintain the equilibrium between yin and yang of body, realization is to hypertension, hyperlipidemia, the treatment of hyperglycemic patients, and make better to recover the normal level of blood pressure and regulate blood glucose balance, the effectively generation of prevention of arterial sclerosis and cardiovascular and cerebrovascular disease again, can also promote the absorption regulating power of middle-aged and elderly people, hypertensive cure rate is reached more than 90%, and greatly reduced hyperlipidemia, the generation of hyperglycemia and arteriosclerosis and cardiovascular and cerebrovascular disease.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art can implement according to this with reference to description word.
Embodiment 1
Adopt raw material components to comprise 15 parts of Spica Prunellaes, 10 parts of Radix Puerariaes, 13 parts of Radix Bupleuri, 15 parts of the Cortexs Eucommiae, parasitic 10 parts, 6 parts of methods of preparing this Chinese medicinal capsule of the Radix Astragali, comprise the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 5 minutes, the Cortex Eucommiae is put in the saline of 5% concentration soaks after 10 minutes and salvages and dry, and then sends into together co-grinding in pulverizer and after 10 minutes, crosses 100 mesh sieves;
(2) add 80 parts of pure water to stir in ground product, adjust PH to 6.0, steam 20 minutes;
(3) send into grinding machine for grinding and cross 600 mesh sieves;
(4) decoct and fry to yellow, then cure 5 minutes, keep 5% moisture and evenly spray 0.5% molasses, obtain powders A;
(5) powders A is incapsulated after ultraviolet disinfection in shell, the dose of each capsule is 0.5g;
(6) capsule is packed through cobalt radiation sterilization final vacuum.
Embodiment 2
Adopt raw material components to comprise 20 parts of Spica Prunellaes, 15 parts of Radix Puerariaes, 17 parts of Radix Bupleuri, 20 parts of the Cortexs Eucommiae, parasitic 14 parts, 10 parts of methods of preparing this Chinese medicinal capsule of the Radix Astragali, comprise the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 6 minutes, the Cortex Eucommiae is put in the saline of 7% concentration soaks after 8 minutes and salvages and dry, and then sends into together co-grinding in pulverizer and after 15 minutes, crosses 200 mesh sieves;
(2) add 100 parts of pure water to stir in ground product, adjust PH to 6.4, steam 20-25 minute;
(3) send into grinding machine for grinding and cross 800 mesh sieves;
(4) decoct and fry to yellow, then cure 8 minutes, keep 6% moisture and evenly spray 1.0% molasses, obtain powders A;
(5) powders A is incapsulated after ultraviolet disinfection in shell, the dose of each capsule is 0.5g;
(6) capsule is packed through cobalt radiation sterilization final vacuum.
Embodiment 3
Adopt raw material components to comprise 17 parts of Spica Prunellaes, 12 parts of Radix Puerariaes, 15 parts of Radix Bupleuri, 16 parts of the Cortexs Eucommiae, parasitic 12 parts and 7 parts of methods of preparing this Chinese medicinal capsule of the Radix Astragali, comprise the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 6 minutes, the Cortex Eucommiae is put in the saline of 6% concentration soaks after 9 minutes and salvages and dry, and then sends into together co-grinding in pulverizer and after 12 minutes, crosses 150 mesh sieves;
(2) add 90 parts of pure water to stir in ground product, adjust PH to 6.2, steam 23 minutes;
(3) send into grinding machine for grinding and cross 700 mesh sieves;
(4) decoct and fry to yellow, then cure 7 minutes, keep 5% moisture and evenly spray 0.6% molasses, obtain powders A;
(5) powders A is incapsulated after ultraviolet disinfection in shell, the dose of each capsule is 0.5g;
(6) capsule is packed through cobalt radiation sterilization final vacuum.
Concrete case 1
Side certain, female, 58 years old, headache, dizzy, absent minded, hypomnesis, numb limbs and tense tendons, nocturia increases, cardiopalmus, breast is vexed, weak, measurement systolic pressure is 140-150mmHg, diastolic pressure is 90-100mmHg, take capsule 3 times prepared by the present invention every day, each 3, adhere to taking after one month health obviously comfortable, the mental status is better, hypermnesis, continue again to have taken one month, ill symptoms disappears substantially, measurement systolic pressure is 120-125mmHg, diastolic pressure is 70-75mmHg, realize the normal arterial pressure level of recovering, can realize self regulation, do not need long-term taking and rely on medicament adjusting, and there is not hyperlipidemia, hyperglycemia and arteriosclerosis and cardiovascular and cerebrovascular disease.
Concrete case 2
Beam so-and-so, man, 47 years old, head pulsation distending pain, feel sick, vomiting, chest distress and palpitation symptoms, irritated, cardiopalmus, insomnia, emotional, whole body arteriolospasm and limb muscle blood supply insufficiency, numb limbs and tense tendons, nape muscular tone, ache, epistaxis even, measurement systolic pressure is 165-170mmHg, diastolic pressure is 105-108mmHg, take capsule 3 times prepared by the present invention every day, each 3, after adhering to taking one and a half months, no longer there is numb limbs and tense tendons, nape muscular tone, ache and the symptom of epistaxis, continue again to have taken one month, physical recovery is normal, happy, full of physical strength, measurement systolic pressure is 123-127mmHg, diastolic pressure is 73-75mmHg, and never there is hyperlipidemia, hyperglycemia and arteriosclerosis and cardiovascular and cerebrovascular disease, it is stable that blood pressure keeps, capacity of self-regulation is better.
Embodiment 4
Adopting raw material components is the methods of 15 parts of Spica Prunellaes, 10 parts of Radix Puerariaes, 13 parts of Radix Bupleuri, 15 parts of the Cortexs Eucommiae, 10 parts of parasitisms, the Radix Astragali 6 12 parts of Fen, Herba Siegesbeckiaes, 9 parts of Rhizoma Chuanxiongs, 15 parts of Radix Achyranthis Bidentataes, 6 parts of Radix Salviae Miltiorrhizaes, 8 parts of Rhizoma Polygoni Cuspidati, 6 parts of Folium Allii tuberosi, 5 parts of Herba Lysimachiaes, 12 parts of Semen Coiciss, 10 parts of Fructus Lyciis, 5 parts of the Radix Paeoniae Albas, 15 parts of Semen Cassiaes, 3 parts of Artemisia anethoicles Mattf, 3 parts of Herba Lophatheris, 10 parts of Cortex Moutans, 2 parts of these Chinese medicinal capsules of preparation of Radix Glycyrrhizae, comprises the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 5 minutes, the Cortex Eucommiae is put in the saline of 5% concentration soaks after 10 minutes and salvages and dry, and then sends into together co-grinding in pulverizer and after 10 minutes, crosses 100 mesh sieves;
(2) add 80 parts of pure water to stir in ground product, adjust PH to 6.0, steam 20 minutes;
(3) send into grinding machine for grinding and cross 600 mesh sieves;
(4) decoct and fry to yellow, then cure 5 minutes, keep 5% moisture and evenly spray 0.5% molasses, obtain powders A;
(5) clean Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae to dry; Then Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae are pulverized respectively and cross 100 mesh sieves after add 100 parts of mix and blends of pure water to decoct after 10 minutes to grind 600 mesh sieves and dried to obtain powder B;
(6) described powders A and powder B mix homogeneously are incapsulated in shell after ultraviolet disinfection, the dose of each capsule is 0.5g;
(7) capsule is packed through cobalt radiation sterilization final vacuum.
Embodiment 5
Adopting raw material components is the methods of 20 parts of Spica Prunellaes, 15 parts of Radix Puerariaes, 17 parts of Radix Bupleuri, 20 parts of the Cortexs Eucommiae, 14 parts of parasitisms, the Radix Astragali 10 15 parts of Fen, Herba Siegesbeckiaes, 13 parts of Rhizoma Chuanxiongs, 20 parts of Radix Achyranthis Bidentataes, 8 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Polygoni Cuspidati, 8 parts of Folium Allii tuberosi, 7 parts of Herba Lysimachiaes, 17 parts of Semen Coiciss, 15 parts of Fructus Lyciis, 7 parts of the Radix Paeoniae Albas, 20 parts of Semen Cassiaes, 5 parts of Artemisia anethoicles Mattf, 5 parts of Herba Lophatheris, 15 parts of Cortex Moutans, 3 parts of these Chinese medicinal capsules of preparation of Radix Glycyrrhizae, comprises the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 6 minutes, the Cortex Eucommiae is put in the saline of 7% concentration soaks after 8 minutes and salvages and dry, and then sends into together co-grinding in pulverizer and after 15 minutes, crosses 200 mesh sieves;
(2) add 100 parts of pure water to stir in ground product, adjust PH to 6.4, steam 25 minutes;
(3) send into grinding machine for grinding and cross 800 mesh sieves;
(4) decoct and fry to yellow, then cure 5-8 minute, keep the moisture of 5-6% and evenly spray 1.0% molasses, obtain powders A;
(5) clean Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae to dry; Then Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae are pulverized respectively and cross 200 mesh sieves after add 120 parts of mix and blends of pure water to decoct after 15 minutes to grind 800 mesh sieves and dried to obtain powder B;
(6) described powders A and powder B mix homogeneously are incapsulated in shell after ultraviolet disinfection, the dose of each capsule is 0.5g;
(7) capsule is packed through cobalt radiation sterilization final vacuum.
Embodiment 6
Adopting raw material components is the methods of 17 parts of Spica Prunellaes, 12 parts of Radix Puerariaes, 15 parts of Radix Bupleuri, 16 parts of the Cortexs Eucommiae, 12 parts of parasitisms, the Radix Astragali 7 13 parts of Fen, Herba Siegesbeckiaes, 12 parts of Rhizoma Chuanxiongs, 16 parts of Radix Achyranthis Bidentataes, 7 parts of Radix Salviae Miltiorrhizaes, 9 parts of Rhizoma Polygoni Cuspidati, 7 parts of Folium Allii tuberosi, 6 parts of Herba Lysimachiaes, 15 parts of Semen Coiciss, 13 parts of Fructus Lyciis, 7 parts of the Radix Paeoniae Albas, 18 parts of Semen Cassiaes, 5 parts of Artemisia anethoicles Mattf, 4 parts of Herba Lophatheris, 15 parts of Cortex Moutans and 2 parts of these Chinese medicinal capsules of preparation of Radix Glycyrrhizae, comprises the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 6 minutes, the Cortex Eucommiae is put in the saline of 6% concentration soaks after 9 minutes and salvages and dry, and then sends into together co-grinding in pulverizer and after 13 minutes, crosses 150 mesh sieves;
(2) add 90 parts of pure water to stir in ground product, adjust PH to 6.2, steam 22 minutes;
(3) send into grinding machine for grinding and cross 700 mesh sieves;
(4) decoct and fry to yellow, then cure 7 minutes, keep 6% moisture and evenly spray 0.7% molasses, obtain powders A;
(5) clean Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae to dry; Then Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae are pulverized respectively and cross 150 mesh sieves after add 110 parts of mix and blends of pure water to decoct after 12 minutes to grind 700 mesh sieves and dried to obtain powder B;
(6) described powders A and powder B mix homogeneously are incapsulated in shell after ultraviolet disinfection, the dose of each capsule is 0.5g;
(7) capsule is packed through cobalt radiation sterilization final vacuum.
Concrete case 3
Lee so-and-so, man, 69 years old, the pure pain of head persistence, obnubilation, twitch, long-term ears tinnitus, shortness of breath and palpitation, common hands refers to, toe numbness or skin are as the sense of ant row, point dumb, measurement systolic pressure is 175-180mmHg, diastolic pressure is 109-112mmHg, take capsule 3 times prepared by the present invention every day, each 3, adhering to taking ill symptoms after two months constantly takes a turn for the better, the mental status is good, add in right amount and walk about, adhere to taking again after one and a half months, ill symptoms seldom occurs substantially, and measurement systolic pressure is 125-128mmHg, diastolic pressure is 72-80mmHg, blood pressure recovers normal level, capsule every day of taking again prepared by the present invention 2 times, each 2, adhere to taking 1 month, blood pressure is basicly stable, and recover capacity of self-regulation, and there is not hyperlipidemia, hyperglycemia and arteriosclerosis and cardiovascular and cerebrovascular disease.
Although embodiment of the present invention are open as above, but it is not restricted to listed utilization in description and embodiment, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other modification, therefore do not deviating under the general concept that claim and equivalency range limit, the present invention is not limited to specific details.

Claims (6)

1. the hypertensive Chinese medicinal capsule for the treatment of, is characterized in that, mainly by the crude drug of following components by weight percent, is made: Spica Prunellae 15-20 part, Radix Puerariae 10-15 part, Radix Bupleuri 13-17 part, Cortex Eucommiae 15-20 part, parasitic 10-14 part, Radix Astragali 6-10 part.
2. treat as claimed in claim 1 hypertensive Chinese medicinal capsule, it is characterized in that, also comprise crude drug: Herba Siegesbeckiae 12-15 part, Rhizoma Chuanxiong 9-13 part, Radix Achyranthis Bidentatae 15-20 part, Radix Salviae Miltiorrhizae 6-8 part, Rhizoma Polygoni Cuspidati 8-10 part, Folium Allii tuberosi 6-8 part, Herba Lysimachiae 5-7 part, Semen Coicis 12-17 part, Fructus Lycii 10-15 part, Radix Paeoniae Alba 5-7 part, Semen Cassiae 15-20 part, Artemisia anethoicles Mattf 3-5 part, Herba Lophatheri 3-5 part, Cortex Moutan 10-15 part, Radix Glycyrrhizae 2-3 part of following components by weight percent.
3. treat as claimed in claim 2 hypertensive Chinese medicinal capsule, it is characterized in that, described Chinese medicinal capsule is made by the raw material of following components by weight percent: 2 parts, 17 parts of Spica Prunellaes, 12 parts of Radix Puerariaes, 15 parts of Radix Bupleuri, 16 parts of the Cortexs Eucommiae, parasitic 12 parts, the Radix Astragali 7 13 parts of Fen, Herba Siegesbeckiaes, 12 parts of Rhizoma Chuanxiongs, 16 parts of Radix Achyranthis Bidentataes, 7 parts of Radix Salviae Miltiorrhizaes, 9 parts of Rhizoma Polygoni Cuspidati, 7 parts of Folium Allii tuberosi, 6 parts of Herba Lysimachiaes, 15 parts of Semen Coiciss, 13 parts of Fructus Lyciis, 7 parts of the Radix Paeoniae Albas, 18 parts of Semen Cassiaes, 5 parts of Artemisia anethoicles Mattf, 4 parts of Herba Lophatheris, 15 parts of Cortex Moutans and Radix Glycyrrhizae.
4. treat as claimed in claim 1 hypertensive Chinese medicinal capsule, it is characterized in that, described Chinese medicinal capsule is made by the raw material of following components by weight percent: 7 parts of 17 parts of Spica Prunellaes, 12 parts of Radix Puerariaes, 15 parts of Radix Bupleuri, 16 parts of the Cortexs Eucommiae, parasitic 12 parts and the Radixs Astragali.
5. a preparation method for the treatment of hypertensive Chinese medicinal capsule, is characterized in that, adopts as the raw material components of any one in claim 1-4, comprises the steps:
(1) Spica Prunellae, Radix Puerariae, Radix Bupleuri, the Cortex Eucommiae, parasitism and the Radix Astragali are cleaned and dried, Radix Bupleuri, the Cortex Eucommiae and the Radix Astragali are cut oblique sheet, Radix Puerariae stripping and slicing shape, Spica Prunellae and parasitic cutting, then Radix Bupleuri is steeped in yellow wine and salvage and dry after 5-6 minute, the Cortex Eucommiae is put in the saline of 5-7% concentration soaks after 8-10 minute and salvages and dry, and then sends into together and in pulverizer, after co-grinding 10-15 minute, crosses 100-200 mesh sieve;
(2) add 80-100 part pure water to stir in ground product, adjust PH to 6.0-6.4, steam 20-25 minute;
(3) send into grinding machine for grinding and cross 600-800 mesh sieve;
(4) decoct and fry to yellow, then cure 5-8 minute, keep the moisture of 5-6% and evenly spray the molasses of 0.5-1.0%, obtain powders A;
(5) powders A is incapsulated after ultraviolet disinfection in shell, the dose of each capsule is 0.5g;
(6) capsule is packed through cobalt radiation sterilization final vacuum.
6. treat as claimed in claim 5 the preparation method of hypertensive Chinese medicinal capsule, it is characterized in that, adopt as the raw material components of claim 2 or 3, described step also comprises that: cleans Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae to dry; Then Herba Siegesbeckiae, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Folium Allii tuberosi, Herba Lysimachiae, Semen Coicis, Fructus Lycii, the Radix Paeoniae Alba, Semen Cassiae, Artemisia anethoicles Mattf, Herba Lophatheri, Cortex Moutan and Radix Glycyrrhizae are pulverized respectively and cross 100-200 mesh sieve after add pure water 100-120 part mix and blend to decoct after 10-15 minute to grind 600-800 mesh sieve and dried to obtain powder B; Described powders A and the sterilizing of powder B mix homogeneously are incapsulated in shell, the dose of each capsule is 0.5g again.
CN201410322791.XA 2014-07-08 2014-07-08 It is a kind of to treat Chinese medicinal capsule of hypertension and preparation method thereof Expired - Fee Related CN104042673B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410322791.XA CN104042673B (en) 2014-07-08 2014-07-08 It is a kind of to treat Chinese medicinal capsule of hypertension and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410322791.XA CN104042673B (en) 2014-07-08 2014-07-08 It is a kind of to treat Chinese medicinal capsule of hypertension and preparation method thereof

Publications (2)

Publication Number Publication Date
CN104042673A true CN104042673A (en) 2014-09-17
CN104042673B CN104042673B (en) 2017-09-05

Family

ID=51496396

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410322791.XA Expired - Fee Related CN104042673B (en) 2014-07-08 2014-07-08 It is a kind of to treat Chinese medicinal capsule of hypertension and preparation method thereof

Country Status (1)

Country Link
CN (1) CN104042673B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524259A (en) * 2014-12-10 2015-04-22 常州诺瑞格纳米科技有限公司 Drink with effect of treating high blood pressure
CN105012415A (en) * 2015-07-31 2015-11-04 蒋魏 Medicine for treating hypertension
CN105567520A (en) * 2016-02-22 2016-05-11 亳州市益众堂保健食品有限公司 Healthy liquor for strengthening kidney and yang and preparation method thereof
CN112107618A (en) * 2020-09-22 2020-12-22 天马(安徽)国药科技股份有限公司 Salvia miltiorrhiza powder preparation process and drying device thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406672A (en) * 2008-11-16 2009-04-15 路敦祥 Chinese medicinal liquor for treating hypertension and preparation method thereof
CN102389466A (en) * 2011-11-21 2012-03-28 何庆勇 Traditional Chinese medicinal composition for treating hypertension and its application
CN103656303A (en) * 2013-12-17 2014-03-26 青岛中科菲力工程技术研发有限公司 Traditional Chinese medicine capsule with function of reducing blood pressure and preparation method of traditional Chinese medicine capsule
CN103735889A (en) * 2013-12-14 2014-04-23 郑明立 Drug for treating pyelonephritis and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406672A (en) * 2008-11-16 2009-04-15 路敦祥 Chinese medicinal liquor for treating hypertension and preparation method thereof
CN102389466A (en) * 2011-11-21 2012-03-28 何庆勇 Traditional Chinese medicinal composition for treating hypertension and its application
CN103735889A (en) * 2013-12-14 2014-04-23 郑明立 Drug for treating pyelonephritis and preparation method thereof
CN103656303A (en) * 2013-12-17 2014-03-26 青岛中科菲力工程技术研发有限公司 Traditional Chinese medicine capsule with function of reducing blood pressure and preparation method of traditional Chinese medicine capsule

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
巫大平: "高血压病的中医证侯及用药规律研究", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524259A (en) * 2014-12-10 2015-04-22 常州诺瑞格纳米科技有限公司 Drink with effect of treating high blood pressure
CN105012415A (en) * 2015-07-31 2015-11-04 蒋魏 Medicine for treating hypertension
CN105567520A (en) * 2016-02-22 2016-05-11 亳州市益众堂保健食品有限公司 Healthy liquor for strengthening kidney and yang and preparation method thereof
CN112107618A (en) * 2020-09-22 2020-12-22 天马(安徽)国药科技股份有限公司 Salvia miltiorrhiza powder preparation process and drying device thereof

Also Published As

Publication number Publication date
CN104042673B (en) 2017-09-05

Similar Documents

Publication Publication Date Title
CN103656238B (en) A kind of Chinese medicine composition for the treatment of rheumatic osteopathia
CN1628760A (en) Traditional Chinese medicinal formulation for treating cardiovascular and cerebrovascular disease
CN101284105A (en) Thrombolysis lipid-lowering pellet for curing cardio-cerebrovascular disease
CN104606513A (en) Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine
CN104826033A (en) Traditional Chinese medicine composition for treating coronary heart disease and preparation method thereof
CN104042673A (en) Traditional Chinese medicinal capsule for treating hypertension and preparation method thereof
CN102247562A (en) Chinese medicinal formula for treating acne
CN104069474B (en) Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method thereof
CN100512852C (en) Composite Chinese medicine took orally for treating coronary heart disease
CN104857210A (en) Traditional Chinese medicine combination preparation for treating fatty liver and preparation method thereof
CN104825905A (en) Traditional Chinese medicine preparation for treating blood transfusion reaction and method for manufacturing traditional Chinese medicine preparation
CN1245197C (en) Chinese medicine preparation for treating coronary heart disease and viral myocarditis
CN105250569A (en) Traditional Chinese medicine pill for treating peripheral neuritis and preparation method
CN104857121A (en) Drug combination for curing hyperlipidemia and application thereof
CN105079721A (en) Traditional Chinese medicine composition for treating osteoarthritis and preparing method thereof
CN104800610A (en) Traditional Chinese medicine preparation for treating Parkinson&#39;s disease and preparation method thereof
CN101357208A (en) Traditional Chinese medicine composition for treating chronic superficial gastritis
CN103784879A (en) Compound traditional Chinese medicinal preparation for treating ischemic cerebrovascular diseases
CN103212026A (en) Traditional Chinese medicine for treating cholelithiasis as well as preparation method and taking method thereof
CN103330861B (en) Medicine for curing cholera and preparation method thereof
CN103432422B (en) Traditional Chinese medicine for treating chronic gastritis
CN105125860A (en) Preparation for effectively treating osteoporosis
CN105250618A (en) Antiviral traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof
CN104984162A (en) Traditional Chinese medicine preparation with effects of dampness dispelling and collateral dredging
CN104383334A (en) Medicine for cleaning intestinal toxins and preparation method of medicine

Legal Events

Date Code Title Description
PB01 Publication
C06 Publication
SE01 Entry into force of request for substantive examination
C10 Entry into substantive examination
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20191112

Address after: 5, building 750, block D, 315000 Yuan Yuan Road, Gaoxin District, Ningbo, Zhejiang

Patentee after: Ningbo Pubinfo Industry Co., Ltd.

Address before: 530299 150, eight foot Jiang Road, Yongning District, the Guangxi Zhuang Autonomous Region, Nanning

Patentee before: Zhang Jianeng

TR01 Transfer of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20170905

Termination date: 20200708

CF01 Termination of patent right due to non-payment of annual fee