CN101006119A - 三唑树枝状大分子的点击化学途径 - Google Patents

三唑树枝状大分子的点击化学途径 Download PDF

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Publication number
CN101006119A
CN101006119A CNA2005800284873A CN200580028487A CN101006119A CN 101006119 A CN101006119 A CN 101006119A CN A2005800284873 A CNA2005800284873 A CN A2005800284873A CN 200580028487 A CN200580028487 A CN 200580028487A CN 101006119 A CN101006119 A CN 101006119A
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dendritic
generation
dendritic structure
product
preparation
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Chinese (zh)
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V·福金
B·K·夏普勒斯
P·吴
A·费尔德曼
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Scripps Research Institute
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Scripps Research Institute
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNA2005800284873A 2004-06-30 2005-06-30 三唑树枝状大分子的点击化学途径 Pending CN101006119A (zh)

Applications Claiming Priority (2)

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US58481704P 2004-06-30 2004-06-30
US60/584,817 2004-06-30

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CN101006119A true CN101006119A (zh) 2007-07-25

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US (1) US20090069561A1 (https=)
EP (1) EP1765910A4 (https=)
JP (1) JP2008505224A (https=)
CN (1) CN101006119A (https=)
AU (1) AU2005260751A1 (https=)
CA (1) CA2572063A1 (https=)
WO (1) WO2006005046A2 (https=)

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CN102153748A (zh) * 2010-12-07 2011-08-17 浙江大学 具有聚集诱导发光性能的超支化聚三唑及其制备方法和应用
CN102585220A (zh) * 2012-01-16 2012-07-18 浙江大学 一种超支化聚三唑甲酸酯及其制备方法和应用
CN105771942A (zh) * 2014-12-26 2016-07-20 中国科学院大连化学物理研究所 一种磁性纳米材料及其制备与应用
CN114262435A (zh) * 2021-12-20 2022-04-01 大连理工大学 一种基于炔烃、胺、叠氮的三组分聚合制备手性聚甲胺基三唑的方法及应用

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US7208243B2 (en) * 2004-12-01 2007-04-24 Toyota Technical Center Usa, Inc. Proton exchange membranes using cycloaddition reaction between azide and alkyne containing components
US8071718B2 (en) 2004-12-22 2011-12-06 General Electric Company Selective radiolabeling of biomolecules
EP1733742A1 (en) * 2005-06-17 2006-12-20 Universiteit Utrecht Holding B.V. Dendrimers multivalently substituted with active groups
US20070020620A1 (en) * 2005-07-14 2007-01-25 Finn M G Compositions and methods for coupling a plurality of compounds to a scaffold
CN101283046A (zh) * 2005-07-18 2008-10-08 斯克里普斯研究学院 制备两亲性树枝状聚合物的方法
WO2007011967A2 (en) * 2005-07-18 2007-01-25 The Scripps Research Institute Method of using click chemistry to functionalize dendrimers
US20070060658A1 (en) * 2005-08-31 2007-03-15 Diaz David D Stabilization of organogels and hydrogels by azide-alkyne [3+2] cycloaddition
EP2147042A4 (en) * 2007-04-26 2012-10-10 Univ Queensland DENDRITIC MOLECULES
US8927682B2 (en) * 2007-08-24 2015-01-06 Board Of Trustees Of Michigan State University Functionalization of polyglycolides by “click” chemistry
US8394914B2 (en) * 2007-08-24 2013-03-12 Board Of Trustees Of Michigan State University Functional polyglycolide nanoparticles derived from unimolecular micelles
WO2009151687A2 (en) 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
US8034396B2 (en) 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
JP5093680B2 (ja) * 2008-06-26 2012-12-12 独立行政法人産業技術総合研究所 ビス四級アンモニウム塩コア型デンドリマー
US8877676B2 (en) * 2008-07-09 2014-11-04 Postech Academy-Industry Foundation Heterogeneous copper nanocatalyst and manufacturing methods thereof
US8889635B2 (en) 2008-09-30 2014-11-18 The Regents Of The University Of Michigan Dendrimer conjugates
WO2010054321A2 (en) 2008-11-07 2010-05-14 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
US8877170B2 (en) * 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
EP2398519A2 (en) 2009-02-21 2011-12-28 Sofradim Production Compounds and medical devices activated with solvophobic linkers
US9523159B2 (en) 2009-02-21 2016-12-20 Covidien Lp Crosslinked fibers and method of making same using UV radiation
WO2010095045A1 (en) 2009-02-21 2010-08-26 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
EP2398584A2 (en) 2009-02-21 2011-12-28 Sofradim Production Apparatus and method of reaching polymers by exposure to uv radiation to produce injectable medical devices
WO2010095056A2 (en) 2009-02-21 2010-08-26 Sofradim Production Medical devices with an activated coating
US8968733B2 (en) 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
US8663689B2 (en) * 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
US9039979B2 (en) 2009-02-21 2015-05-26 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
EP2398524B1 (en) 2009-02-21 2017-07-12 Covidien LP Medical devices having activated surfaces
WO2010095049A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same by extrusion
CA2753188A1 (en) 2009-02-21 2010-08-26 Tyco Healthcare Group Lp Medical devices having activated surfaces
US20120232225A1 (en) * 2009-08-26 2012-09-13 The Regents Of The University Of Michigan Synthesis and isolation of dendrimer systems
CN102917699A (zh) 2009-10-13 2013-02-06 密执安大学评议会 树枝状聚合物组合物和合成方法
US8912323B2 (en) 2009-10-30 2014-12-16 The Regents Of The University Of Michigan Multifunctional small molecules
AU2011231245B2 (en) 2010-03-25 2015-03-26 Covidien Lp Medical devices incorporating functional adhesives
CA2794336A1 (en) * 2010-03-25 2011-09-29 Sofradim Production Surgical fasteners and methods for sealing wounds
CA2804263A1 (en) 2010-06-29 2012-01-12 Tyco Healthcare Group Lp Microwave-powered reactor and method for in situ forming implants
EP2588153A2 (en) 2010-07-01 2013-05-08 Sofradim Production Medical device with predefined activated cellular integration
EP2598178B1 (en) 2010-07-27 2018-07-11 Sofradim Production Polymeric fibers having tissue reactive members
US9402911B2 (en) 2011-12-08 2016-08-02 The Regents Of The University Of Michigan Multifunctional small molecules
FR2996554B1 (fr) * 2012-10-08 2014-11-28 Commissariat Energie Atomique Nouveaux azotures, procedes de fabrication et leurs applications
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
JP6564369B2 (ja) 2013-12-09 2019-08-21 デュレクト コーポレイション 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法
WO2016154029A1 (en) * 2015-03-20 2016-09-29 Massachusetts Institute Of Technology Formation of macromolecules using iterative growth and related compounds
WO2019145025A1 (en) * 2018-01-24 2019-08-01 Ecole Polytechnique Federale De Lausanne (Epfl) Covalent polymer network semiconducting thin-films and method for producing thereof
WO2025059162A1 (en) 2023-09-11 2025-03-20 Dana-Farber Cancer Institute, Inc. Car-engager containing il-2 variants to enhance the functionality of car t cells

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US2864683A (en) * 1953-10-30 1958-12-16 Monsanto Chemicals Selective method of inhibiting preemergent growth of grasses
JP3023053B2 (ja) * 1993-07-07 2000-03-21 ミネソタ マイニング アンド マニュファクチャリング カンパニー ジポラロフィルで誘導したアジドポリマー
WO1998030575A1 (en) * 1997-01-08 1998-07-16 Proligo Llc Bioconjugation of macromolecules
AU2003240482B2 (en) * 2002-05-30 2009-03-12 The Scripps Research Institute Copper-catalysed ligation of azides and acetylenes

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102153748A (zh) * 2010-12-07 2011-08-17 浙江大学 具有聚集诱导发光性能的超支化聚三唑及其制备方法和应用
CN102153748B (zh) * 2010-12-07 2012-11-07 浙江大学 具有聚集诱导发光性能的超支化聚三唑及其制备方法和应用
CN102585220A (zh) * 2012-01-16 2012-07-18 浙江大学 一种超支化聚三唑甲酸酯及其制备方法和应用
CN105771942A (zh) * 2014-12-26 2016-07-20 中国科学院大连化学物理研究所 一种磁性纳米材料及其制备与应用
CN105771942B (zh) * 2014-12-26 2018-06-29 中国科学院大连化学物理研究所 一种磁性纳米材料及其制备与应用
CN114262435A (zh) * 2021-12-20 2022-04-01 大连理工大学 一种基于炔烃、胺、叠氮的三组分聚合制备手性聚甲胺基三唑的方法及应用
CN114262435B (zh) * 2021-12-20 2023-02-14 大连理工大学 一种基于炔烃、胺、叠氮的三组分聚合制备手性聚甲胺基三唑的方法及应用

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WO2006005046A9 (en) 2006-03-09
US20090069561A1 (en) 2009-03-12
EP1765910A2 (en) 2007-03-28
WO2006005046A3 (en) 2006-11-30
CA2572063A1 (en) 2006-01-12
EP1765910A4 (en) 2009-12-30
WO2006005046A2 (en) 2006-01-12
AU2005260751A1 (en) 2006-01-12
JP2008505224A (ja) 2008-02-21

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Open date: 20070725