JP2008505224A - トリアゾールデンドリマーへのクリックケミストリールート - Google Patents

トリアゾールデンドリマーへのクリックケミストリールート Download PDF

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Publication number
JP2008505224A
JP2008505224A JP2007519518A JP2007519518A JP2008505224A JP 2008505224 A JP2008505224 A JP 2008505224A JP 2007519518 A JP2007519518 A JP 2007519518A JP 2007519518 A JP2007519518 A JP 2007519518A JP 2008505224 A JP2008505224 A JP 2008505224A
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dendron
generation
group
product
dendrimer
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JP2008505224A5 (https=
Inventor
フォーキン，ヴァレリー
シャープレス，バリー・ケイ
ウー，ペン
フェルドマン，アリーナ
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ザ スクリプス リサーチ インスティテュート
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Publication of JP2008505224A publication Critical patent/JP2008505224A/ja
Publication of JP2008505224A5 publication Critical patent/JP2008505224A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
JP2007519518A 2004-06-30 2005-06-30 トリアゾールデンドリマーへのクリックケミストリールート Pending JP2008505224A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58481704P 2004-06-30 2004-06-30
PCT/US2005/023718 WO2006005046A2 (en) 2004-06-30 2005-06-30 Click chemistry route to triazole dendrimers

Publications (2)

Publication Number Publication Date
JP2008505224A true JP2008505224A (ja) 2008-02-21
JP2008505224A5 JP2008505224A5 (https=) 2008-08-14

Family

ID=35783400

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007519518A Pending JP2008505224A (ja) 2004-06-30 2005-06-30 トリアゾールデンドリマーへのクリックケミストリールート

Country Status (7)

Country Link
US (1) US20090069561A1 (https=)
EP (1) EP1765910A4 (https=)
JP (1) JP2008505224A (https=)
CN (1) CN101006119A (https=)
AU (1) AU2005260751A1 (https=)
CA (1) CA2572063A1 (https=)
WO (1) WO2006005046A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522014A (ja) * 2004-12-01 2008-06-26 トヨタ テクニカル センター，ユー．エス．エー．，インコーポレイティド アジドとアルキン含有成分の間の付加環化反応を用いる新規プロトン交換膜
JP2010006733A (ja) * 2008-06-26 2010-01-14 National Institute Of Advanced Industrial & Technology ビス四級アンモニウム塩コア型デンドリマー
JP2011527628A (ja) * 2008-07-09 2011-11-04 ポステック アカデミー−インダストリー ファンデーション 不均一銅ナノ触媒およびその製造方法

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US8071718B2 (en) 2004-12-22 2011-12-06 General Electric Company Selective radiolabeling of biomolecules
EP1733742A1 (en) * 2005-06-17 2006-12-20 Universiteit Utrecht Holding B.V. Dendrimers multivalently substituted with active groups
US20070020620A1 (en) * 2005-07-14 2007-01-25 Finn M G Compositions and methods for coupling a plurality of compounds to a scaffold
US20090306310A1 (en) * 2005-07-18 2009-12-10 The Scripps Research Institute Method of using click chemistry to functionalize dendrimers
JP2009506136A (ja) * 2005-07-18 2009-02-12 ザ スクリプス リサーチ インスティテュート 両親媒性デンドリマーの製法
US20070060658A1 (en) * 2005-08-31 2007-03-15 Diaz David D Stabilization of organogels and hydrogels by azide-alkyne [3+2] cycloaddition
EP2147042A4 (en) * 2007-04-26 2012-10-10 Univ Queensland DENDRITIC MOLECULES
US8394914B2 (en) * 2007-08-24 2013-03-12 Board Of Trustees Of Michigan State University Functional polyglycolide nanoparticles derived from unimolecular micelles
US8927682B2 (en) * 2007-08-24 2015-01-06 Board Of Trustees Of Michigan State University Functionalization of polyglycolides by “click” chemistry
WO2009151687A2 (en) 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
US8034396B2 (en) 2008-04-01 2011-10-11 Tyco Healthcare Group Lp Bioadhesive composition formed using click chemistry
WO2010039861A2 (en) 2008-09-30 2010-04-08 The Regents Of The University Of Michigan Dendrimer conjugates
US9017644B2 (en) 2008-11-07 2015-04-28 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
WO2010096654A1 (en) 2009-02-21 2010-08-26 Tyco Healthcare Group Lp Medical devices having activated surfaces
CA2753171A1 (en) 2009-02-21 2010-08-26 Sofradim Production Crosslinked fibers and method of making same using uv radiation
US8512728B2 (en) 2009-02-21 2013-08-20 Sofradim Production Method of forming a medical device on biological tissue
WO2010095047A2 (en) 2009-02-21 2010-08-26 Sofradim Production Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices
AU2010215196B2 (en) 2009-02-21 2015-04-16 Covidien Lp Crosslinked fibers and method of making same by extrusion
US8535477B2 (en) 2009-02-21 2013-09-17 Sofradim Production Medical devices incorporating functional adhesives
US8969473B2 (en) 2009-02-21 2015-03-03 Sofradim Production Compounds and medical devices activated with solvophobic linkers
EP2398584A2 (en) 2009-02-21 2011-12-28 Sofradim Production Apparatus and method of reaching polymers by exposure to uv radiation to produce injectable medical devices
US8877170B2 (en) 2009-02-21 2014-11-04 Sofradim Production Medical device with inflammatory response-reducing coating
US8968733B2 (en) 2009-02-21 2015-03-03 Sofradim Production Functionalized surgical adhesives
CA2753162A1 (en) 2009-02-21 2010-08-26 Sofradim Production Amphiphilic compounds and self-assembling compositions made therefrom
US8663689B2 (en) 2009-02-21 2014-03-04 Sofradim Production Functionalized adhesive medical gel
EP2398850B1 (en) 2009-02-21 2018-08-22 Sofradim Production Medical devices with an activated coating
AU2010215931A1 (en) 2009-02-21 2011-10-13 Covidien Lp Medical devices having activated surfaces
WO2011028334A2 (en) * 2009-08-26 2011-03-10 The Regents Of The University Of Michigan Synthesis and isolation of dendrimer systems
WO2011059609A2 (en) 2009-10-13 2011-05-19 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
WO2011059586A2 (en) 2009-10-30 2011-05-19 The Regents Of The University Of Michigan Multifunctional small molecules
US8795331B2 (en) 2010-03-25 2014-08-05 Covidien Lp Medical devices incorporating functional adhesives
US9272074B2 (en) * 2010-03-25 2016-03-01 Sofradim Production Surgical fasteners and methods for sealing wounds
AU2011276443A1 (en) 2010-06-29 2013-01-31 Covidien Lp Microwave-powered reactor and method for in situ forming implants
WO2012001532A2 (en) 2010-07-01 2012-01-05 Sofradim Production Medical device with predefined activated cellular integration
WO2012014080A2 (en) 2010-07-27 2012-02-02 Sofradim Production Polymeric fibers having tissue reactive members
CN102153748B (zh) * 2010-12-07 2012-11-07 浙江大学 具有聚集诱导发光性能的超支化聚三唑及其制备方法和应用
WO2013085718A1 (en) 2011-12-08 2013-06-13 The Regents Of The University Of Michigan Multifunctional small molecules
CN102585220B (zh) * 2012-01-16 2013-07-24 浙江大学 一种超支化聚三唑甲酸酯及其制备方法和应用
FR2996554B1 (fr) * 2012-10-08 2014-11-28 Commissariat Energie Atomique Nouveaux azotures, procedes de fabrication et leurs applications
US9775928B2 (en) 2013-06-18 2017-10-03 Covidien Lp Adhesive barbed filament
EP3079668A1 (en) 2013-12-09 2016-10-19 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
CN105771942B (zh) * 2014-12-26 2018-06-29 中国科学院大连化学物理研究所 一种磁性纳米材料及其制备与应用
US10125124B2 (en) 2015-03-20 2018-11-13 Massachusetts Institute Of Technology Formation of macromolecules using iterative growth and related compounds
WO2019145025A1 (en) * 2018-01-24 2019-08-01 Ecole Polytechnique Federale De Lausanne (Epfl) Covalent polymer network semiconducting thin-films and method for producing thereof
CN114262435B (zh) * 2021-12-20 2023-02-14 大连理工大学 一种基于炔烃、胺、叠氮的三组分聚合制备手性聚甲胺基三唑的方法及应用
WO2025059162A1 (en) 2023-09-11 2025-03-20 Dana-Farber Cancer Institute, Inc. Car-engager containing il-2 variants to enhance the functionality of car t cells

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864683A (en) * 1953-10-30 1958-12-16 Monsanto Chemicals Selective method of inhibiting preemergent growth of grasses
JPH0770314A (ja) * 1993-07-07 1995-03-14 Minnesota Mining & Mfg Co <3M> ジポラロフィルで誘導したアジドポリマー
JP2001509828A (ja) * 1997-01-08 2001-07-24 プロリゴ・エルエルシー 高分子のバイオコンジュゲーション
JP2006502099A (ja) * 2002-05-30 2006-01-19 ザ スクリプス リサーチ インスティテュート 銅を触媒とするアジドとアセチレンのライゲーション

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864683A (en) * 1953-10-30 1958-12-16 Monsanto Chemicals Selective method of inhibiting preemergent growth of grasses
JPH0770314A (ja) * 1993-07-07 1995-03-14 Minnesota Mining & Mfg Co <3M> ジポラロフィルで誘導したアジドポリマー
JP2001509828A (ja) * 1997-01-08 2001-07-24 プロリゴ・エルエルシー 高分子のバイオコンジュゲーション
JP2006502099A (ja) * 2002-05-30 2006-01-19 ザ スクリプス リサーチ インスティテュート 銅を触媒とするアジドとアセチレンのライゲーション

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522014A (ja) * 2004-12-01 2008-06-26 トヨタ テクニカル センター，ユー．エス．エー．，インコーポレイティド アジドとアルキン含有成分の間の付加環化反応を用いる新規プロトン交換膜
JP2010006733A (ja) * 2008-06-26 2010-01-14 National Institute Of Advanced Industrial & Technology ビス四級アンモニウム塩コア型デンドリマー
JP2011527628A (ja) * 2008-07-09 2011-11-04 ポステック アカデミー−インダストリー ファンデーション 不均一銅ナノ触媒およびその製造方法

Also Published As

Publication number Publication date
WO2006005046A3 (en) 2006-11-30
WO2006005046A2 (en) 2006-01-12
EP1765910A2 (en) 2007-03-28
CA2572063A1 (en) 2006-01-12
US20090069561A1 (en) 2009-03-12
CN101006119A (zh) 2007-07-25
WO2006005046A9 (en) 2006-03-09
AU2005260751A1 (en) 2006-01-12
EP1765910A4 (en) 2009-12-30

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