CN100482632C - (r)-2-烷基-3-苯基丙酸的制备 - Google Patents

(r)-2-烷基-3-苯基丙酸的制备 Download PDF

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Publication number
CN100482632C
CN100482632C CNB018122310A CN01812231A CN100482632C CN 100482632 C CN100482632 C CN 100482632C CN B018122310 A CNB018122310 A CN B018122310A CN 01812231 A CN01812231 A CN 01812231A CN 100482632 C CN100482632 C CN 100482632C
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CN
China
Prior art keywords
formula
alkyl
alkoxy
compound
methoxy
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CNB018122310A
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English (en)
Chinese (zh)
Other versions
CN1440379A (zh
Inventor
P·赫罗尔德
S·斯图茨
F·斯平德勒
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Speedel Pharma AG
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Speedel Pharma AG
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Publication date
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Publication of CN1440379A publication Critical patent/CN1440379A/zh
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Publication of CN100482632C publication Critical patent/CN100482632C/zh
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Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
CNB018122310A 2000-07-03 2001-06-26 (r)-2-烷基-3-苯基丙酸的制备 Expired - Fee Related CN100482632C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1317/00 2000-07-03
CH13172000 2000-07-03
CH1317/2000 2000-07-03

Publications (2)

Publication Number Publication Date
CN1440379A CN1440379A (zh) 2003-09-03
CN100482632C true CN100482632C (zh) 2009-04-29

Family

ID=4565374

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018122310A Expired - Fee Related CN100482632C (zh) 2000-07-03 2001-06-26 (r)-2-烷基-3-苯基丙酸的制备

Country Status (11)

Country Link
US (1) US6683206B2 (https=)
EP (1) EP1296927B1 (https=)
JP (1) JP2004502663A (https=)
CN (1) CN100482632C (https=)
AR (1) AR028783A1 (https=)
AT (1) ATE546425T1 (https=)
AU (1) AU2001273761A1 (https=)
BR (1) BR0112146A (https=)
CA (1) CA2414839C (https=)
TW (1) TWI271398B (https=)
WO (1) WO2002002500A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH694251A5 (de) * 1999-07-14 2004-10-15 Eprova Ag Herstellung von Tetrahydropterin und Derivaten.
EP1296912B1 (en) * 2000-07-03 2006-01-25 Speedel Pharma AG Process for the preparation of (r)-2-alkyl-3-phenyl-1-propanols
CA2412910C (en) * 2000-07-03 2010-11-16 Solvias Ag Ferrocenyl diphosphines and their use
AT501193B1 (de) 2004-12-27 2007-03-15 Dsm Fine Chem Austria Gmbh Verfahen zur übergangsmetall - katalysierten asymmetrischen hydrierung von acrylsäurederivaten
GB0500700D0 (en) * 2005-01-14 2005-02-23 Stylacats Ltd Process for the manufacture of 2-alkyl-3-phenylpropionic acids and alcohols
DE102005012408A1 (de) * 2005-03-17 2006-09-21 Basf Ag Verfahren zur Herstellung von optisch aktiven 3-Phenylpropionsäurederivaten und Folgeprodukten davon
JP4763771B2 (ja) * 2005-03-17 2011-08-31 ビーエーエスエフ ソシエタス・ヨーロピア 光学活性３−フェニルプロピオン酸誘導体を生成する方法、およびその誘導体の後続生成物
DE102005052195A1 (de) 2005-10-28 2007-05-03 Reuter Chemischer Apparatebau Kg Verfahren zur Herstellung von chiralen Octensäurederivaten
US7935841B2 (en) 2006-04-21 2011-05-03 Dr. Reddy's Laboratories Limited Bisphospholanes for use as catalysts in asymmetric reactions
EP1939182A1 (de) * 2006-12-22 2008-07-02 Speedel Experimenta AG Verfahren zur Herstellung von (R oder S)-2-Alkyl-3-heterocyclyl-1-propanolen
EP1958666A1 (en) 2007-02-13 2008-08-20 Speedel Experimenta AG Heterocyclic-substituted alkanamides as therapeutic compounds
US8088954B2 (en) * 2007-07-11 2012-01-03 Dsm Ip Assets B.V. Preparation of a saturated aldehyde
EP2178816A1 (en) * 2007-07-11 2010-04-28 DSM Fine Chemicals Austria Nfg GmbH & Co KG Alpha-substituted , -unsaturated e- or z-aldehydes, use thereof, and processes for their preparation ,
DE102007049039A1 (de) 2007-10-11 2009-04-16 Reuter Chemischer Apparatebau Kg Verfahren zur Herstellung von 8-Hydrazino-8-Aryl-Octanoylderivaten und deren Verwendung
US8203005B2 (en) 2009-10-29 2012-06-19 Carbo Design Llc Manufacturing process for enantiomerically pure 8-aryloctanoic acids as Aliskiren
TW201202178A (en) 2010-06-04 2012-01-16 Chemo Iberica Sa Process for producing Aliskiren
US8703976B2 (en) 2011-10-02 2014-04-22 Milan Soukup Manufacturing process for 8-aryloctanoic acids such as Aliskiren
WO2013061224A1 (en) 2011-10-25 2013-05-02 Jubilant Life Sciences Limited Process for the preparation of aliskiren

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426216A (en) * 1990-12-28 1995-06-20 Society Nationale Elf Aquitaine Process for the hydrogenation of ethylenically unsaturated organic compounds and ruthenium catalysts for carrying out said process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307232A (en) * 1980-03-21 1981-12-22 E. I. Du Pont De Nemours And Company Preparation of dialkyl- and diarylphosphonoalkanoic acids and substituted acrylic acids
US5659065A (en) * 1994-04-18 1997-08-19 Novartis Corporation Alpha-aminoalkanoic acids and reduction products
JPH09309826A (ja) * 1996-05-22 1997-12-02 Kissei Pharmaceut Co Ltd 糸球体疾患の予防および治療剤
US6258833B1 (en) * 1999-12-23 2001-07-10 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426216A (en) * 1990-12-28 1995-06-20 Society Nationale Elf Aquitaine Process for the hydrogenation of ethylenically unsaturated organic compounds and ruthenium catalysts for carrying out said process

Also Published As

Publication number Publication date
CA2414839C (en) 2010-02-16
EP1296927A1 (en) 2003-04-02
EP1296927B1 (en) 2012-02-22
CN1440379A (zh) 2003-09-03
TWI271398B (en) 2007-01-21
BR0112146A (pt) 2003-05-06
JP2004502663A (ja) 2004-01-29
AU2001273761A1 (en) 2002-01-14
AR028783A1 (es) 2003-05-21
US6683206B2 (en) 2004-01-27
CA2414839A1 (en) 2002-01-10
US20030139625A1 (en) 2003-07-24
ATE546425T1 (de) 2012-03-15
WO2002002500A1 (en) 2002-01-10

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Granted publication date: 20090429

Termination date: 20120626