CN100438906C - 共聚物1和相关肽和多肽及其处理过的t细胞在保护cns细胞避免谷氨酸毒性中的用途 - Google Patents

共聚物1和相关肽和多肽及其处理过的t细胞在保护cns细胞避免谷氨酸毒性中的用途 Download PDF

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CN100438906C
CN100438906C CNB018065910A CN01806591A CN100438906C CN 100438906 C CN100438906 C CN 100438906C CN B018065910 A CNB018065910 A CN B018065910A CN 01806591 A CN01806591 A CN 01806591A CN 100438906 C CN100438906 C CN 100438906C
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glutamate
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CN1462190A (zh
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M·埃斯森巴奇-施瓦尔茨
E·约勒斯
J·基普尼斯
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Yeda Research and Development Co Ltd
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/47—Brain; Nervous system

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB018065910A 2000-06-07 2001-01-22 共聚物1和相关肽和多肽及其处理过的t细胞在保护cns细胞避免谷氨酸毒性中的用途 Expired - Lifetime CN100438906C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20979900P 2000-06-07 2000-06-07
US60/209,799 2000-06-07
US62021600A 2000-07-20 2000-07-20
US09/620,216 2000-07-20

Publications (2)

Publication Number Publication Date
CN1462190A CN1462190A (zh) 2003-12-17
CN100438906C true CN100438906C (zh) 2008-12-03

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CNB018065910A Expired - Lifetime CN100438906C (zh) 2000-06-07 2001-01-22 共聚物1和相关肽和多肽及其处理过的t细胞在保护cns细胞避免谷氨酸毒性中的用途

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US (1) US20020037848A1 (https=)
EP (1) EP1294390B1 (https=)
JP (1) JP4328090B2 (https=)
KR (1) KR20030007397A (https=)
CN (1) CN100438906C (https=)
AT (1) ATE314860T1 (https=)
AU (1) AU783031B2 (https=)
CA (1) CA2398277C (https=)
CY (1) CY1105263T1 (https=)
DE (1) DE60116467T2 (https=)
DK (1) DK1294390T3 (https=)
ES (1) ES2256200T3 (https=)
IL (2) IL150801A0 (https=)
MX (1) MXPA02007109A (https=)
NZ (1) NZ520282A (https=)
WO (1) WO2001093893A2 (https=)

Families Citing this family (35)

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WO2000005250A1 (en) 1998-07-23 2000-02-03 Yeda Research And Development Co., Ltd Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides
ES2527760T3 (es) 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7022663B2 (en) 2000-02-18 2006-04-04 Yeda Research And Development Co., Ltd. Oral, nasal and pulmonary dosage formulations of copolymer 1
CA2411536A1 (en) * 2000-06-05 2001-12-13 V. Wee Yong The use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
WO2002076503A1 (en) 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
SI1459065T1 (sl) 2001-12-04 2010-11-30 Teva Pharma Postopki za merjenje potentnosti glatiramer acetata
IL160105A0 (en) * 2001-12-06 2004-06-20 Yeda Res & Dev Vaccine for treatment of motor neurone diseases
CN102580069B (zh) * 2003-01-07 2015-09-30 耶达研究及发展有限公司 用于治疗性免疫接种的含共聚物1的滴眼用疫苗
WO2005056574A2 (en) 2003-12-09 2005-06-23 Yeda Research And Development Co. Ltd. Method and vaccine comprising copolymer 1 for treatment of psychiatric disorders
CA2540701A1 (en) * 2003-09-29 2005-04-07 Chugai Seiyaku Kabushiki Kaisha Proteins expressed in nk cells
US7585843B2 (en) * 2003-10-03 2009-09-08 Bayhill Therapeutics, Inc. Treatment of demyelinating autoimmune disease with modified ordered peptides
CA2546077C (en) * 2003-11-12 2016-07-05 Yeda Research And Development Co. Ltd. Vaccine and method for treatment of neurodegenerative diseases
KR20070036062A (ko) 2004-05-07 2007-04-02 펩팀문, 인코포레이티드 랜덤 공중합체에 의해 질병을 치료하는 방법
US7495072B2 (en) 2004-09-09 2009-02-24 Teva Pharmaceutical Industries, Ltd. Process for preparation of mixtures of polypeptides using purified hydrobromic acid
AU2005308396B2 (en) * 2004-11-29 2011-06-09 Yeda Research And Development Co. Ltd. Induction of neurogenesis and stem cell therapy in combination with Copolymer 1
EP2016095A2 (en) 2006-04-13 2009-01-21 Peptimmune, Inc. Methods for designing and synthesizing directed sequence polymer compositions via the directed expansion of epitope permeability
US8193147B2 (en) 2007-09-24 2012-06-05 Hadasit Medical Research Services & Development Ltd. Use of copolymer 1 for treatment of muscular dystrophy
BRPI0817682A2 (pt) 2007-10-16 2015-04-07 Peptimmune Inc Métodos para projetar e preparar vacinas compreendendo composições de polímero de sequência direcionada via a expansão direta de epítopos
WO2009063459A2 (en) * 2007-11-13 2009-05-22 Yeda Research And Development Co. Ltd Synthetic peptide copolymers for treatment of neurodevelopmental disorders
ES2612001T4 (es) 2009-08-20 2018-02-07 Yeda Research & Development Company, Ltd. Terapia de baja frecuencia con acetato de glatirámero
JP5916622B2 (ja) * 2010-01-04 2016-05-11 マピ ファーマ リミテッド グラチラマーまたはその薬理学的に許容される塩を含むデポーシステム
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8377885B2 (en) 2010-01-04 2013-02-19 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) * 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
ES2601892T3 (es) 2011-04-21 2017-02-16 Mapi Pharma Limited Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
EP2892353A4 (en) 2012-09-10 2016-10-26 Yeda Res & Dev INDIVIDUALIZED IMMUNOMODULATION THERAPY FOR NEURODEGENERATIVE ILLNESSES, CNS LESIONS AND AGGREGATIVE DEMENTIA
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HUE071047T2 (hu) 2016-08-31 2025-07-28 Mapi Pharma Ltd Glatiramer-acetátot tartalmazó depórendszerek
CN110382052A (zh) 2017-03-26 2019-10-25 Mapi医药公司 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统
EP4340853A4 (en) * 2021-05-20 2025-05-07 Washington University Neuroprotective compositions and methods
KR20230128606A (ko) * 2022-02-28 2023-09-05 경상국립대학교산학협력단 티로신을 유효성분으로 함유하는 알츠하이머병의 예방, 개선 또는 치료용 조성물

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US3849550A (en) * 1971-04-21 1974-11-19 Yeda Res & Dev Therapeutic copolymer
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WO1999041247A1 (en) * 1998-02-13 1999-08-19 Autoimmune, Inc. TREATMENT OF MULTIPLE SCLEROSIS USING COP-1 AND Th2-ENHANCING CYTOKINES

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CY1105263T1 (el) 2010-03-03
CN1462190A (zh) 2003-12-17
AU783031B2 (en) 2005-09-15
DE60116467D1 (de) 2006-03-30
IL150801A0 (en) 2003-02-12
DE60116467T2 (de) 2006-11-02
WO2001093893A2 (en) 2001-12-13
IL150801A (en) 2007-10-31
AU3451801A (en) 2001-12-17
JP2004507460A (ja) 2004-03-11
HK1058892A1 (zh) 2004-06-11
NZ520282A (en) 2004-09-24
KR20030007397A (ko) 2003-01-23
MXPA02007109A (es) 2002-12-13
CA2398277A1 (en) 2001-12-13
WO2001093893A3 (en) 2002-04-04
CA2398277C (en) 2013-09-03
ATE314860T1 (de) 2006-02-15
DK1294390T3 (da) 2006-04-03
EP1294390B1 (en) 2006-01-04
EP1294390A2 (en) 2003-03-26
ES2256200T3 (es) 2006-07-16
US20020037848A1 (en) 2002-03-28
JP4328090B2 (ja) 2009-09-09

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