CN100341496C - 预防或治疗肾脏疾病的药剂 - Google Patents
预防或治疗肾脏疾病的药剂 Download PDFInfo
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- CN100341496C CN100341496C CNB038109735A CN03810973A CN100341496C CN 100341496 C CN100341496 C CN 100341496C CN B038109735 A CNB038109735 A CN B038109735A CN 03810973 A CN03810973 A CN 03810973A CN 100341496 C CN100341496 C CN 100341496C
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- straight
- branched alkyl
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- ethyl
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- YEZNLOUZAIOMLT-UHFFFAOYSA-N tolfenamic acid Chemical compound CC1=C(Cl)C=CC=C1NC1=CC=CC=C1C(O)=O YEZNLOUZAIOMLT-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
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- C—CHEMISTRY; METALLURGY
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- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
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- C07D277/28—Radicals substituted by nitrogen atoms
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2002081769 | 2002-03-22 | ||
JP081769/2002 | 2002-03-22 |
Publications (2)
Publication Number | Publication Date |
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CN1652761A CN1652761A (zh) | 2005-08-10 |
CN100341496C true CN100341496C (zh) | 2007-10-10 |
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Application Number | Title | Priority Date | Filing Date |
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CNB038109735A Expired - Fee Related CN100341496C (zh) | 2002-03-22 | 2003-03-18 | 预防或治疗肾脏疾病的药剂 |
Country Status (11)
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US (1) | US7563822B2 (de) |
EP (1) | EP1491187A4 (de) |
JP (1) | JP4532119B2 (de) |
KR (1) | KR100964908B1 (de) |
CN (1) | CN100341496C (de) |
AR (1) | AR039096A1 (de) |
AU (1) | AU2003221042A1 (de) |
CA (1) | CA2479254A1 (de) |
MX (1) | MXPA04009234A (de) |
TW (1) | TWI262073B (de) |
WO (1) | WO2003080038A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2319504T3 (es) * | 2000-10-04 | 2009-05-08 | Kissei Pharmaceutical Co., Ltd. | Derivados de 5-amidino-2-hidroxibencenosulfonamida, composisiones farmaceuticas que los contienen e intermedios para su preparacion. |
WO2005027896A1 (ja) * | 2003-09-19 | 2005-03-31 | Kissei Pharmaceutical Co., Ltd. | 併用医薬 |
KR20070053239A (ko) * | 2004-09-06 | 2007-05-23 | 코와 가부시키가이샤 | 사구체 질환 치료제 |
JP2010536880A (ja) | 2007-08-22 | 2010-12-02 | ギリード・コロラド・インコーポレーテッド | 糖尿病の合併症のための療法 |
EP3388509A1 (de) | 2008-11-12 | 2018-10-17 | inRegen | Isolierte nierenzellen und verwendungen davon |
WO2011070049A1 (en) * | 2009-12-09 | 2011-06-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Endothelin inhibitors for the treatment of rapidly progressive glomerulonephritis |
NZ603376A (en) | 2010-05-03 | 2014-10-31 | Tengion Inc | Smooth muscle cell constructs |
TWI542690B (zh) | 2010-05-12 | 2016-07-21 | 再生醫學Tx有限責任公司 | 生物活性腎細胞 |
WO2011156642A1 (en) | 2010-06-11 | 2011-12-15 | Tengion, Inc. | Erythropoietin-expressing adipose cell populations |
US9255931B2 (en) * | 2010-06-24 | 2016-02-09 | Morehouse School Of Medicine | Method and compositions for the treatment and detection of endothelin-1 related kidney diseases |
CA3065694A1 (en) | 2010-11-10 | 2012-05-18 | Inregen | Methods of forming injectable formulations for providing regenerative effects to an organ such as a kidney |
KR102215476B1 (ko) | 2012-10-24 | 2021-02-17 | 인리젠 | 신장 세포 모집단 및 이의 용도 |
PT2994528T (pt) | 2013-05-08 | 2024-02-13 | Prokidney | Organoides compreendendo células renais isoladas e utilizações dos mesmos |
US11123372B2 (en) | 2016-07-29 | 2021-09-21 | Prokidney | Bioactive renal cells for the treatment of chronic kidney disease |
CN106588847B (zh) * | 2016-12-09 | 2019-08-13 | 上海中医药大学 | 二氢香豆素类衍生物及其制备方法和应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1265091A (zh) * | 1997-07-25 | 2000-08-30 | 橘生药品工业株式会社 | 氨乙基苯氧基乙酸衍生物及用于缓解尿结石症的疼痛和促进排石的药物 |
WO2000050390A1 (en) * | 1999-02-25 | 2000-08-31 | Fibrogen, Inc. | N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of c-proteinase and for treating or preventing disorders related to unregulated collagen production |
CN1268116A (zh) * | 1997-08-27 | 2000-09-27 | 橘生药品工业株式会社 | 3-脒基苯胺衍生物,活化血凝固因子x抑制剂和制备这些物质的中间体 |
EP1174421A1 (de) * | 1999-03-31 | 2002-01-23 | Kissei Pharmaceutical Co., Ltd. | 3-amidinobenzenesulfonamid-derivate, sie enthaltende medizinische zubereitungen und zwischenprodukte in ihrer herstellung |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000007626A1 (en) * | 1998-08-07 | 2000-02-17 | Smithkline Beecham Corporation | Use of anti-coagulation factor antibodies as long-lasting protective agents |
ES2319504T3 (es) * | 2000-10-04 | 2009-05-08 | Kissei Pharmaceutical Co., Ltd. | Derivados de 5-amidino-2-hidroxibencenosulfonamida, composisiones farmaceuticas que los contienen e intermedios para su preparacion. |
-
2003
- 2003-03-18 WO PCT/JP2003/003229 patent/WO2003080038A1/ja active Application Filing
- 2003-03-18 KR KR1020047015021A patent/KR100964908B1/ko not_active IP Right Cessation
- 2003-03-18 MX MXPA04009234A patent/MXPA04009234A/es active IP Right Grant
- 2003-03-18 CN CNB038109735A patent/CN100341496C/zh not_active Expired - Fee Related
- 2003-03-18 US US10/508,209 patent/US7563822B2/en not_active Expired - Fee Related
- 2003-03-18 JP JP2003577867A patent/JP4532119B2/ja not_active Expired - Fee Related
- 2003-03-18 CA CA002479254A patent/CA2479254A1/en not_active Abandoned
- 2003-03-18 AU AU2003221042A patent/AU2003221042A1/en not_active Abandoned
- 2003-03-18 EP EP03712737A patent/EP1491187A4/de not_active Withdrawn
- 2003-03-21 TW TW092106299A patent/TWI262073B/zh not_active IP Right Cessation
- 2003-03-21 AR ARP030100993A patent/AR039096A1/es not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1265091A (zh) * | 1997-07-25 | 2000-08-30 | 橘生药品工业株式会社 | 氨乙基苯氧基乙酸衍生物及用于缓解尿结石症的疼痛和促进排石的药物 |
CN1268116A (zh) * | 1997-08-27 | 2000-09-27 | 橘生药品工业株式会社 | 3-脒基苯胺衍生物,活化血凝固因子x抑制剂和制备这些物质的中间体 |
WO2000050390A1 (en) * | 1999-02-25 | 2000-08-31 | Fibrogen, Inc. | N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of c-proteinase and for treating or preventing disorders related to unregulated collagen production |
EP1174421A1 (de) * | 1999-03-31 | 2002-01-23 | Kissei Pharmaceutical Co., Ltd. | 3-amidinobenzenesulfonamid-derivate, sie enthaltende medizinische zubereitungen und zwischenprodukte in ihrer herstellung |
Also Published As
Publication number | Publication date |
---|---|
AR039096A1 (es) | 2005-02-09 |
TW200403987A (en) | 2004-03-16 |
EP1491187A1 (de) | 2004-12-29 |
JP4532119B2 (ja) | 2010-08-25 |
AU2003221042A1 (en) | 2003-10-08 |
CN1652761A (zh) | 2005-08-10 |
EP1491187A4 (de) | 2008-04-16 |
KR20040101347A (ko) | 2004-12-02 |
MXPA04009234A (es) | 2005-01-25 |
JPWO2003080038A1 (ja) | 2005-07-21 |
US20050107354A1 (en) | 2005-05-19 |
WO2003080038A1 (fr) | 2003-10-02 |
US7563822B2 (en) | 2009-07-21 |
KR100964908B1 (ko) | 2010-06-23 |
TWI262073B (en) | 2006-09-21 |
CA2479254A1 (en) | 2003-10-02 |
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