CL2016001677A1 - 5-flúor-4-imino-3-(alquil/alquilo sustituido)-1-(arilsulfonil)-3,4-dihidropirimidin-2(1h)-ona y los procesos para su preparación. - Google Patents
5-flúor-4-imino-3-(alquil/alquilo sustituido)-1-(arilsulfonil)-3,4-dihidropirimidin-2(1h)-ona y los procesos para su preparación.Info
- Publication number
- CL2016001677A1 CL2016001677A1 CL2016001677A CL2016001677A CL2016001677A1 CL 2016001677 A1 CL2016001677 A1 CL 2016001677A1 CL 2016001677 A CL2016001677 A CL 2016001677A CL 2016001677 A CL2016001677 A CL 2016001677A CL 2016001677 A1 CL2016001677 A1 CL 2016001677A1
- Authority
- CL
- Chile
- Prior art keywords
- alkyl
- imino
- dihydropyrimidin
- arylsulfonyl
- fluoro
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 title 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 title 1
- 125000000547 substituted alkyl group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
- C07D333/10—Thiophene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361922572P | 2013-12-31 | 2013-12-31 | |
| US201361922582P | 2013-12-31 | 2013-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2016001677A1 true CL2016001677A1 (es) | 2016-12-09 |
Family
ID=53480979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2016001677A CL2016001677A1 (es) | 2013-12-31 | 2016-06-29 | 5-flúor-4-imino-3-(alquil/alquilo sustituido)-1-(arilsulfonil)-3,4-dihidropirimidin-2(1h)-ona y los procesos para su preparación. |
Country Status (24)
| Country | Link |
|---|---|
| US (8) | US20150183749A1 (OSRAM) |
| EP (4) | EP3097096A4 (OSRAM) |
| JP (3) | JP6585057B2 (OSRAM) |
| CN (4) | CN111362881A (OSRAM) |
| AP (1) | AP2016009342A0 (OSRAM) |
| AU (2) | AU2014373959B2 (OSRAM) |
| BR (2) | BR102014033037B1 (OSRAM) |
| CA (2) | CA2935594C (OSRAM) |
| CL (1) | CL2016001677A1 (OSRAM) |
| CR (2) | CR20160343A (OSRAM) |
| DO (1) | DOP2016000163A (OSRAM) |
| EA (2) | EA036389B1 (OSRAM) |
| EC (1) | ECSP16064249A (OSRAM) |
| IL (3) | IL246512B (OSRAM) |
| MX (2) | MX392211B (OSRAM) |
| NI (1) | NI201600094A (OSRAM) |
| NZ (2) | NZ722439A (OSRAM) |
| PE (1) | PE20161174A1 (OSRAM) |
| PH (1) | PH12016501284A1 (OSRAM) |
| SG (2) | SG11201605377VA (OSRAM) |
| TW (2) | TWI667229B (OSRAM) |
| UA (2) | UA129860C2 (OSRAM) |
| UY (2) | UY35943A (OSRAM) |
| WO (2) | WO2015103142A1 (OSRAM) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2015008444A (es) | 2012-12-28 | 2015-09-23 | Dow Agrosciences Llc | Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida. |
| JP6324994B2 (ja) | 2012-12-28 | 2018-05-16 | アダマ・マクテシム・リミテッド | N−(置換)−5−フルオロ−4−イミノ−3−メチル−2−オキソ−3,4−ジヒドロピリミジン−1(2h)−カルボキシレート誘導体 |
| ES2874475T3 (es) | 2012-12-31 | 2021-11-05 | Adama Makhteshim Ltd | Derivados de la 3,4-dihidropirimidin-2(1h)-ona 3-alquil-5-fluoro-4-iminosustituida como fungicidas |
| EA036389B1 (ru) | 2013-12-31 | 2020-11-03 | Адама Мактешим Лтд. | 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он и способы их получения |
| US9532570B2 (en) | 2013-12-31 | 2017-01-03 | Adama Makhteshim Ltd. | Synergistic fungicidal mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one for fungal control in cereals |
| UY36964A (es) | 2015-10-27 | 2017-05-31 | Bayer Cropscience Ag | Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida |
| JP6922271B2 (ja) * | 2016-03-11 | 2021-08-18 | 住友化学株式会社 | 植物病害防除組成物及び植物病害防除方法 |
| WO2019038583A1 (en) | 2017-07-17 | 2019-02-28 | Adama Makhteshim Ltd. | 5-FLUORO-4-IMINO-3-METHYL-1-TOSYL-3,4-DIHYDROPYRIMIDIN-2-ONE POLYMORPHS |
| CR20210270A (es) * | 2018-11-05 | 2021-07-20 | Adama Makhteshim Ltd | Mezclas y composiciones que comprenden 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2-ona, y métodos de uso de los mismos |
| JP2022541318A (ja) | 2019-07-22 | 2022-09-22 | アダマ・マクテシム・リミテッド | 殺菌組合せ物、混合物および組成物、ならびにそれらの使用 |
| CN114599639A (zh) * | 2019-09-23 | 2022-06-07 | 阿达玛马克西姆有限公司 | 用于制备5-(氟-4-亚氨基-3-甲基)-1-甲苯磺酰基-3,4-二氢嘧啶-(1h)-酮的方法 |
| WO2021181274A1 (en) * | 2020-03-09 | 2021-09-16 | Adama Makhteshim Ltd. | Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one |
| CR20220610A (es) | 2020-05-04 | 2023-01-10 | Adama Makhteshim Ltd | Mezclas y composiciones que comprenden 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2-ona, y métodos de uso de las mismas |
| EP4649827A2 (en) | 2020-07-08 | 2025-11-19 | Adama Makhteshim Ltd. | Fungicidal mixtures |
| EP4284173A1 (en) | 2021-01-27 | 2023-12-06 | Adama Makhteshim Ltd. | 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1 h)-one for controlling plant diseases |
| BR112023023105A2 (pt) | 2021-05-04 | 2024-01-30 | Adama Makhteshim Ltd | Formas cristalinas de 5-fluoro-4-imino-3-metil-1-tosil-3,4-di-hidropirimidin-2-ona, e misturas, composições e métodos de uso das mesmas |
| IL311455A (en) | 2021-09-15 | 2024-05-01 | Adama Makhteshim Ltd | Method for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-H1-pyrimidin-2-one |
| EP4486126A1 (en) | 2022-03-03 | 2025-01-08 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| WO2023228148A1 (en) | 2022-05-26 | 2023-11-30 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| AU2023318916A1 (en) | 2022-08-03 | 2025-02-20 | Adama Makhteshim Ltd. | 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1h)-one for fungicide-resistant fungus |
| CN120882310A (zh) | 2023-03-09 | 2025-10-31 | 安道麦马克西姆有限公司 | 杀真菌组合、混合物及组合物以及其用途 |
| CN120882311A (zh) | 2023-03-14 | 2025-10-31 | 安道麦马克西姆有限公司 | 含有5-(氟-4-亚氨基-3-甲基)-1-甲苯磺酰基-3,4二氢嘧啶-(1h)-酮及其衍生物以及uv吸收剂的液体组合物 |
| TW202444696A (zh) * | 2023-03-23 | 2024-11-16 | 以色列商安道麥馬克西姆有限公司 | 用於製備5-氟-4-亞胺基-3-甲基-1-(甲苯-4-磺醯基)-3,4-二氫-1h-嘧啶-2-酮的方法 |
| WO2025046581A1 (en) | 2023-08-31 | 2025-03-06 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereo |
| IL308593A (en) | 2023-11-15 | 2025-06-01 | Adama Makhteshim Ltd | Reducing environmental impact of fungicidal enhancement |
| WO2025114931A1 (en) | 2023-11-28 | 2025-06-05 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| WO2025203024A1 (en) | 2024-03-26 | 2025-10-02 | Adama Makhteshim Ltd. | Process for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-1h-pyrimidin-2-one |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3309359A (en) | 1965-10-22 | 1967-03-14 | Hoffmann La Roche | N-mono-acyl-5-fluorocytosine derivatives and process |
| US3368938A (en) | 1966-01-13 | 1968-02-13 | Hoffmann La Roche | Controlling fungi with 5-fluorocytosine |
| US3635977A (en) | 1969-11-03 | 1972-01-18 | American Cyanamid Co | Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil |
| US3868373A (en) | 1970-01-27 | 1975-02-25 | Hoffmann La Roche | 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines |
| US4009272A (en) | 1971-10-23 | 1977-02-22 | Bayer Aktiengesellschaft | Penicillins |
| CH579057A5 (OSRAM) | 1973-09-07 | 1976-08-31 | Hoffmann La Roche | |
| JPS601793B2 (ja) | 1979-12-06 | 1985-01-17 | 松下電器産業株式会社 | カラ−テレビジョン受像機の画質改善装置 |
| FR2530636A1 (fr) | 1982-07-23 | 1984-01-27 | Rhone Poulenc Agrochimie | Nouveaux derives de la tetrahydro-2,3,6,7 5h-thiazolo (3,2-a) pyrimidine, leur preparation et leur utilisation comme herbicides |
| EP0139613A1 (de) | 1983-08-29 | 1985-05-02 | Ciba-Geigy Ag | N-(2-Nitrophenyl)-4-aminopyrimidin-Derivate, deren Herstellung und Verwendung |
| US4845081A (en) | 1984-10-18 | 1989-07-04 | University Of Florida | Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes |
| EP0230922A2 (de) | 1986-01-21 | 1987-08-05 | Boehringer Ingelheim Kg | Verwendung von Peptiden zur Herstellung von Mitteln zur Behandlung von Coronarerkrankungen oder organischem Hirnsyndrom |
| EP0332579B1 (de) | 1988-03-09 | 1994-08-10 | Ciba-Geigy Ag | Mittel zum Schutz von Pflanzen gegen Krankheiten |
| DE3821711A1 (de) | 1988-06-28 | 1990-02-08 | Bayer Ag | Thiazolopyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel |
| US5118816A (en) * | 1990-12-26 | 1992-06-02 | American Cyanamid Company | 2-aryl-5-(trifluoromethyl)-2-pyrroline compounds useful in the manufacture of insecticidal, nematocidal and acaricidal arylpyrroles |
| JP3109012B2 (ja) | 1992-06-18 | 2000-11-13 | クミアイ化学工業株式会社 | チアゾロ[5,4−d]ピリミジン誘導体及び農園芸用殺菌剤 |
| JP3217191B2 (ja) | 1992-07-16 | 2001-10-09 | ビーエーエスエフ アクチェンゲゼルシャフト | ヘテロ芳香族化合物およびこれを含有する植物保護剤 |
| CN1105113C (zh) | 1995-07-05 | 2003-04-09 | 纳幕尔杜邦公司 | 杀真菌嘧啶酮 |
| TR199801813T2 (xx) | 1996-03-11 | 1998-12-21 | Novartis Ag | B�cek �ld�r�c� olarak pirimidin-4- on t�revleri. |
| HRP970239B1 (en) * | 1997-05-09 | 2004-04-30 | Inst Ru Er Bouekovic | Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity |
| GT199900185A (es) | 1998-11-06 | 2001-04-18 | Novedosa pirimidin-4-enamina como fungicida. | |
| AU2002212015B2 (en) | 2000-10-13 | 2007-01-25 | Shire Canada Inc. | Dioxolane analogs for improved inter-cellular delivery |
| WO2003018051A1 (en) | 2001-08-27 | 2003-03-06 | Vic Jira | Anti-fungal composition |
| EP1731523A4 (en) | 2004-04-01 | 2009-08-12 | Takeda Pharmaceutical | THIAZOLOPYRIMIDINDERIVAT |
| US20090163567A1 (en) | 2005-11-22 | 2009-06-25 | Ishihara Sangyo Kaisha, Ltd | Germicide composition for agricultural and gardening applications and method for controlling plant disease |
| US20080004253A1 (en) | 2006-06-30 | 2008-01-03 | Bryan James Branstetter | Thiazolopyrimidine modulators of TRPV1 |
| US20100029483A1 (en) | 2006-10-16 | 2010-02-04 | Rhodia Inc. | Agricultural adjuvant compositions, pesticide compositions, and methods for using such compositions |
| JP5035250B2 (ja) | 2006-10-20 | 2012-09-26 | 住友金属工業株式会社 | 化学プラント用ニッケル材 |
| US20100056468A1 (en) | 2007-01-08 | 2010-03-04 | University Health Network | Pyrimidine Derivatives As Anticancer Agents |
| DK2252594T3 (en) | 2008-01-22 | 2015-11-23 | Dow Agrosciences Llc | 4-amino-5-fluoro-pyrimidine derivatives as fungicides |
| MX2011001091A (es) | 2008-08-01 | 2011-03-15 | Dow Agrosciences Llc | Uso de 5-fluorocitosina como un fungicida. |
| EP2326327B1 (en) | 2008-09-17 | 2016-03-23 | SRI International | Analogs of indole-3-carbinol and their use as agents against infection |
| SI2389375T1 (sl) | 2009-01-23 | 2015-11-30 | Euro-Celtique S.A. | Derivati hidroksamske kisline |
| BR112012002807B1 (pt) | 2009-08-07 | 2018-07-10 | Adama Makhteshim Ltd. | Derivados de 5-flúor-2-oxopirimidina-1(2h)- caboxilato, composição e processo para controle e prevenção de ataque fúngico em uma planta de ataque fúngico em uma planta |
| UA107671C2 (en) | 2009-08-07 | 2015-02-10 | Dow Agrosciences Llc | N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives |
| UA106889C2 (uk) | 2009-08-07 | 2014-10-27 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні n1-ацил-5-фторпіримідинону |
| AU2010279411B2 (en) * | 2009-08-07 | 2014-10-23 | Adama Makhteshim Ltd. | N1-sulfonyl-5-fluoropyrimidinone derivatives |
| UA112284C2 (uk) * | 2009-08-07 | 2016-08-25 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні 5-фторпіримідинону |
| AU2010303832B2 (en) | 2009-10-07 | 2015-02-12 | Dow Agrosciences Llc | Synergistic fungicidal composition containing 5-fluorocytosine for fungal control in cereals |
| HRP20161107T1 (hr) * | 2010-04-26 | 2016-12-30 | Adama Makhteshim Ltd | Derivati n3-supstituiranog-n1-sulfonil-5-fluoropirimidinona |
| AR087549A1 (es) * | 2011-08-17 | 2014-04-03 | Dow Agrosciences Llc | Derivados de 5-fluor-4-imino-3-(sustituido)-3,4-dihidropirimidin-2(1h)ona |
| US9385377B2 (en) | 2012-11-07 | 2016-07-05 | Toyota Jidosha Kabushiki Kaisha | Method for producing a catalyst for fuel cells |
| MX2015008444A (es) * | 2012-12-28 | 2015-09-23 | Dow Agrosciences Llc | Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida. |
| EP3689142A1 (en) | 2012-12-28 | 2020-08-05 | Adama Makhteshim Ltd. | 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives |
| JP6324994B2 (ja) | 2012-12-28 | 2018-05-16 | アダマ・マクテシム・リミテッド | N−(置換)−5−フルオロ−4−イミノ−3−メチル−2−オキソ−3,4−ジヒドロピリミジン−1(2h)−カルボキシレート誘導体 |
| ES2874475T3 (es) * | 2012-12-31 | 2021-11-05 | Adama Makhteshim Ltd | Derivados de la 3,4-dihidropirimidin-2(1h)-ona 3-alquil-5-fluoro-4-iminosustituida como fungicidas |
| EA036389B1 (ru) | 2013-12-31 | 2020-11-03 | Адама Мактешим Лтд. | 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он и способы их получения |
| US9532570B2 (en) | 2013-12-31 | 2017-01-03 | Adama Makhteshim Ltd. | Synergistic fungicidal mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one for fungal control in cereals |
| MA41272A (fr) | 2014-12-23 | 2017-10-31 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences |
-
2014
- 2014-12-29 EA EA201691351A patent/EA036389B1/ru not_active IP Right Cessation
- 2014-12-29 WO PCT/US2014/072566 patent/WO2015103142A1/en not_active Ceased
- 2014-12-29 US US14/584,347 patent/US20150183749A1/en not_active Abandoned
- 2014-12-29 EA EA201691353A patent/EA201691353A1/ru unknown
- 2014-12-29 AP AP2016009342A patent/AP2016009342A0/en unknown
- 2014-12-29 UA UAA201909738A patent/UA129860C2/uk unknown
- 2014-12-29 JP JP2016543735A patent/JP6585057B2/ja active Active
- 2014-12-29 CN CN201911357017.1A patent/CN111362881A/zh active Pending
- 2014-12-29 AU AU2014373959A patent/AU2014373959B2/en active Active
- 2014-12-29 NZ NZ722439A patent/NZ722439A/en unknown
- 2014-12-29 EP EP14877285.8A patent/EP3097096A4/en not_active Ceased
- 2014-12-29 CA CA2935594A patent/CA2935594C/en active Active
- 2014-12-29 MX MX2016008759A patent/MX392211B/es unknown
- 2014-12-29 CN CN201911242098.0A patent/CN111217759A/zh active Pending
- 2014-12-29 EP EP21151157.1A patent/EP3862347A1/en not_active Withdrawn
- 2014-12-29 CR CR20160343A patent/CR20160343A/es unknown
- 2014-12-29 CN CN201480076563.7A patent/CN106068268A/zh active Pending
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