CL2015000038A1 - Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. - Google Patents

Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Info

Publication number
CL2015000038A1
CL2015000038A1 CL2015000038A CL2015000038A CL2015000038A1 CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1 CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1
Authority
CL
Chile
Prior art keywords
methods
intermediates
preparing substituted
substituted triazolopyridines
triazolopyridines
Prior art date
Application number
CL2015000038A
Other languages
English (en)
Spanish (es)
Inventor
Volker Schulze Dr
Franz-Josef Mais Dr
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CL2015000038A1 publication Critical patent/CL2015000038A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2015000038A 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. CL2015000038A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12175640 2012-07-10
EP12185590 2012-09-24
EP13170585 2013-06-05

Publications (1)

Publication Number Publication Date
CL2015000038A1 true CL2015000038A1 (es) 2015-03-13

Family

ID=48793197

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000038A CL2015000038A1 (es) 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Country Status (24)

Country Link
US (1) US9388177B2 (OSRAM)
EP (1) EP2872506A1 (OSRAM)
JP (1) JP6238979B2 (OSRAM)
KR (1) KR20150040845A (OSRAM)
CN (1) CN104603136B (OSRAM)
AP (1) AP3778A (OSRAM)
AU (1) AU2013289381A1 (OSRAM)
BR (1) BR112015000308A2 (OSRAM)
CA (1) CA2878481A1 (OSRAM)
CL (1) CL2015000038A1 (OSRAM)
CO (1) CO7160002A2 (OSRAM)
CR (1) CR20150006A (OSRAM)
DO (1) DOP2015000007A (OSRAM)
EA (1) EA027544B1 (OSRAM)
HK (1) HK1206731A1 (OSRAM)
IL (1) IL236265A (OSRAM)
IN (1) IN2015DN00085A (OSRAM)
MX (1) MX2015000348A (OSRAM)
NZ (1) NZ703020A (OSRAM)
PE (1) PE20150354A1 (OSRAM)
PH (1) PH12015500061A1 (OSRAM)
SG (1) SG11201408419QA (OSRAM)
TN (1) TN2015000008A1 (OSRAM)
WO (1) WO2014009219A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105431435A (zh) * 2013-06-07 2016-03-23 拜耳制药股份公司 具有作为mps-1抑制剂的活性的取代的三唑并吡啶类
EA201600003A1 (ru) 2013-06-11 2016-06-30 Байер Фарма Акциенгезельшафт КОМБИНАЦИИ ДЛЯ ЛЕЧЕНИЯ РАКА, СОДЕРЖАЩИЕ ИНГИБИТОР Mps-1 КИНАЗЫ И ИНГИБИТОР МИТОЗА
DK3008062T3 (en) * 2013-06-11 2017-06-12 Bayer Pharma AG PRODRUG DERIVATIVES OF SUBSTITUTED TRIAZOLOPYRIDINES
EP3283642B1 (en) 2015-04-17 2023-10-11 Netherlands Translational Research Center Holding B.V. Prognostic biomarkers for ttk inhibitor chemotherapy
TW201800408A (zh) 2016-06-15 2018-01-01 拜耳製藥公司 Mps-1抑制劑

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2003030937A1 (ja) * 2001-10-05 2005-01-20 小野薬品工業株式会社 ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤
EP1753428A4 (en) * 2004-05-14 2010-09-15 Abbott Lab INHIBITORS OF KINASES AS THERAPEUTIC AGENTS
UA89503C2 (uk) * 2004-09-13 2010-02-10 Х. Луннбек А/С Заміщені похідні аніліну
MX2007004179A (es) * 2004-10-07 2007-06-07 Warner Lambert Co Derivados de triazolpiridina como agentes antibacterianos.
US20060194823A1 (en) * 2004-12-22 2006-08-31 Georg Kettschau Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
JP2009539840A (ja) * 2006-06-06 2009-11-19 シェーリング コーポレイション プロテインキナーゼ阻害剤としてのイミダゾピラジン
EP1870416A1 (en) * 2006-06-21 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Sulphonamido-macrocycles as tie2 inhibitors
JP5336375B2 (ja) 2006-08-30 2013-11-06 セルゾーム リミテッド キナーゼ阻害剤としてのトリアゾール誘導体
JO3598B1 (ar) * 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
EA201000130A1 (ru) 2007-07-18 2010-08-30 Новартис Аг Бициклические гетероарильные соединения и их применение в качестве ингибиторов киназы
BRPI0815709A2 (pt) 2007-08-23 2017-06-13 Astrazeneca Ab composro, composição farmacêutica, e, uso de um composto.
JP2010536917A (ja) 2007-08-31 2010-12-02 メルク セローノ ソシエテ アノニム トリアゾロピリジン化合物と、ａｓｋ阻害剤としてのその化合物の利用法
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB0724342D0 (en) * 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
US8530689B2 (en) * 2008-05-05 2013-09-10 The Trustees Of The University Of Pennsylvania Processes for the preparation of biphenyl compounds
US20110212053A1 (en) * 2008-06-19 2011-09-01 Dapeng Qian Phosphatidylinositol 3 kinase inhibitors
PE20120110A1 (es) 2009-02-13 2012-02-20 Fovea Pharmaceuticals [1,2,4]triazolo[1,5-a]piridinas como inhibidores de cinasa
ES2547328T3 (es) 2009-04-29 2015-10-05 Bayer Intellectual Property Gmbh Imidazoquinoxalinas sustituidas
WO2010141360A1 (en) * 2009-06-05 2010-12-09 Merck Sharp & Dohme Corp. Biaryl benzotriazole derivatives
TWI500614B (zh) * 2009-06-05 2015-09-21 Cephalon Inc １，２，４－三唑並〔１，５ａ〕吡啶衍生物之製備和用途
JP5728683B2 (ja) 2009-09-04 2015-06-03 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ チロシンスレオニンキナーゼ阻害剤としての置換アミノキノキサリン
EP2343295A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
EP2343294A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
WO2012044567A2 (en) * 2010-09-30 2012-04-05 Merck Sharp & Dohme Corp. Imidazole derivatives
ES2539265T3 (es) * 2011-04-21 2015-06-29 Bayer Intellectual Property Gmbh Triazolopiridinas
WO2012160029A1 (en) * 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk

Also Published As

Publication number Publication date
CO7160002A2 (es) 2015-01-15
BR112015000308A2 (pt) 2017-06-27
JP2015523372A (ja) 2015-08-13
HK1206731A1 (en) 2016-01-15
IN2015DN00085A (OSRAM) 2015-05-29
WO2014009219A1 (en) 2014-01-16
TN2015000008A1 (en) 2016-06-29
US20150148542A1 (en) 2015-05-28
CR20150006A (es) 2015-02-16
IL236265A0 (en) 2015-02-26
NZ703020A (en) 2017-08-25
PE20150354A1 (es) 2015-03-21
EP2872506A1 (en) 2015-05-20
DOP2015000007A (es) 2015-02-15
EA027544B1 (ru) 2017-08-31
JP6238979B2 (ja) 2017-11-29
AP3778A (en) 2016-08-31
CN104603136B (zh) 2017-06-27
AU2013289381A1 (en) 2015-01-22
SG11201408419QA (en) 2015-01-29
AP2014008177A0 (en) 2014-12-31
EA201590116A1 (ru) 2015-07-30
CN104603136A (zh) 2015-05-06
US9388177B2 (en) 2016-07-12
KR20150040845A (ko) 2015-04-15
PH12015500061A1 (en) 2015-03-02
CA2878481A1 (en) 2014-01-16
MX2015000348A (es) 2015-04-14
IL236265A (en) 2017-07-31

Similar Documents

Publication Publication Date Title
CR20140463A (es) Compuestos de heterociclilo como inhibidores de mek
CR20130539A (es) Triazolopiridinas
CR20150370A (es) Compuestos antivirales
UY34602A (es) ?Derivados de bencimidazolil- e imidazopiridinil-metilamina?
UY33943A (es) Derivados espirocíclicos de isoxazolina como agentes antiparasitarios.
UY34836A (es) Nuevo organismos
MX2016004933A (es) Inhibidores de pirimidina del fgfr4.
UY34472A (es) Derivados modificados de 4-fenil-piridina
CO6980657A2 (es) Triazolopiridinas sustituidas
UY34654A (es) Inhibidores de la beta-secretasa
UY33977A (es) Híbrido de pigmento autoaglutinante.
UY34467A (es) Procedimiento para la preparación de 5-fluoro-1h-pirazolopiridinas sustituidas
DOP2015000059A (es) Amino-quinolinas como inhibidores de cinasa
DOP2015000060A (es) Profármacos de aminoquinazolina inhibidora de cinasa
UY33976A (es) Derivados de pirazolo-pirimidina.
CR20140495A (es) 5-amino[1,4]thiazines como inhibidores de bace1
UY4181Q (es) Taza
MX2020011641A (es) Proceso novedoso para la preparacion de pirrolidina-dionas espiroheterociclicas.
UY34612A (es) ?procedimiento para la preparación de derivados de isoxazolina azetidina quirales como agentes antiparasitarios?.
MX369290B (es) Inhibidores de fbx03.
CL2015000038A1 (es) Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.
ECSP13012914A (es) Síntesis de derivados de 2-carboxamida-cicloamino-urea
GT201200328A (es) Intermedios de agomelatina y método de preparación de éstos
UY34286A (es) Diagnóstico de vacuna mejorado
BR112014028443A2 (pt) composição estéril.