CL2014003052A1 - Anticuerpos para la neutralización de la influenza - Google Patents

Anticuerpos para la neutralización de la influenza

Info

Publication number
CL2014003052A1
CL2014003052A1 CL2014003052A CL2014003052A CL2014003052A1 CL 2014003052 A1 CL2014003052 A1 CL 2014003052A1 CL 2014003052 A CL2014003052 A CL 2014003052A CL 2014003052 A CL2014003052 A CL 2014003052A CL 2014003052 A1 CL2014003052 A1 CL 2014003052A1
Authority
CL
Chile
Prior art keywords
influenza
neutralization
antibodies
Prior art date
Application number
CL2014003052A
Other languages
English (en)
Spanish (es)
Inventor
S Raguram
Viswanathan Sasisekharan
Venkataramanan Soundararajan
Ram Sasisekharan
Vidya Subramanian
Kannan Tharakaraman
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of CL2014003052A1 publication Critical patent/CL2014003052A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/108Orthomyxoviridae (F), e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2014003052A 2012-05-10 2014-11-10 Anticuerpos para la neutralización de la influenza CL2014003052A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261645453P 2012-05-10 2012-05-10

Publications (1)

Publication Number Publication Date
CL2014003052A1 true CL2014003052A1 (es) 2015-06-26

Family

ID=49548780

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014003052A CL2014003052A1 (es) 2012-05-10 2014-11-10 Anticuerpos para la neutralización de la influenza

Country Status (14)

Country Link
US (4) US9683030B2 (https=)
EP (2) EP3492101A3 (https=)
JP (2) JP6431477B2 (https=)
KR (1) KR102122618B1 (https=)
CN (2) CN109265541A (https=)
AU (2) AU2013260123A1 (https=)
BR (1) BR112014027991A2 (https=)
CA (1) CA2871160C (https=)
CL (1) CL2014003052A1 (https=)
HK (1) HK1207970A1 (https=)
IL (1) IL235237A0 (https=)
MX (1) MX378749B (https=)
SG (2) SG10201807059QA (https=)
WO (1) WO2013169377A1 (https=)

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EA038407B1 (ru) 2015-02-05 2021-08-24 Янссен Вэксинс Энд Превеншн Б.В. Связывающие молекулы, направленные против гемагглютинина вируса гриппа, и пути их применения
AU2016261299B2 (en) * 2015-05-11 2019-12-05 Janssen Vaccines & Prevention B.V. Influenza virus neutralizing peptidomimetic compounds
WO2017083627A1 (en) 2015-11-13 2017-05-18 Visterra, Inc. Compositions and methods for treating and preventing influenza
CN109195629A (zh) 2016-02-24 2019-01-11 威特拉公司 流行性感冒抗体分子制剂
KR101887876B1 (ko) 2016-08-18 2018-08-13 한국과학기술연구원 H5형 조류독감 바이러스에 특이적으로 결합하는 핵산 압타머 및 이를 이용하는 h5형 조류독감 바이러스의 검출방법
CN113924147A (zh) 2019-03-25 2022-01-11 威特拉公司 用于治疗和预防流感的组合物和方法
CN115551885A (zh) 2019-12-11 2022-12-30 威特拉公司 用于治疗和预防流感的组合物和方法

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Also Published As

Publication number Publication date
CN109265541A (zh) 2019-01-25
AU2018202468B2 (en) 2020-04-16
EP3492101A3 (en) 2019-10-23
HK1207970A1 (en) 2016-02-19
WO2013169377A1 (en) 2013-11-14
EP3492101A2 (en) 2019-06-05
JP6431477B2 (ja) 2018-12-05
JP2015517492A (ja) 2015-06-22
IL235237A0 (en) 2014-12-31
MX2014013678A (es) 2015-02-04
SG10201807059QA (en) 2018-09-27
MX378749B (es) 2025-03-10
KR102122618B1 (ko) 2020-06-29
JP2018118991A (ja) 2018-08-02
US9683030B2 (en) 2017-06-20
BR112014027991A2 (pt) 2017-07-18
SG11201406769RA (en) 2014-11-27
US20190062407A1 (en) 2019-02-28
CA2871160A1 (en) 2013-11-14
EP2846833A1 (en) 2015-03-18
US20170306003A1 (en) 2017-10-26
US10538578B2 (en) 2020-01-21
US20200123234A1 (en) 2020-04-23
CN104507500A (zh) 2015-04-08
AU2018202468A1 (en) 2018-04-26
AU2013260123A1 (en) 2014-11-13
US9982037B2 (en) 2018-05-29
KR20150008180A (ko) 2015-01-21
EP2846833A4 (en) 2016-01-06
US20130302348A1 (en) 2013-11-14
CA2871160C (en) 2023-03-14
US10947300B2 (en) 2021-03-16

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