SG10201807059QA - Agents for influenza neutralization - Google Patents

Agents for influenza neutralization

Info

Publication number
SG10201807059QA
SG10201807059QA SG10201807059QA SG10201807059QA SG10201807059QA SG 10201807059Q A SG10201807059Q A SG 10201807059QA SG 10201807059Q A SG10201807059Q A SG 10201807059QA SG 10201807059Q A SG10201807059Q A SG 10201807059QA SG 10201807059Q A SG10201807059Q A SG 10201807059QA
Authority
SG
Singapore
Prior art keywords
agents
antibodies
influenza
neutralization
influenza neutralization
Prior art date
Application number
SG10201807059QA
Inventor
S Raguram
Viswanathan Sasisekharan
Venkataramanan Soundararajan
Ram Sasisekharan
Vidya Subramanian
Kannan Tharakaraman
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of SG10201807059QA publication Critical patent/SG10201807059QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

AGENTS FOR INFLUENZA NEUTRALIZATION The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza. (No drawing to be published)
SG10201807059QA 2012-05-10 2013-03-14 Agents for influenza neutralization SG10201807059QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261645453P 2012-05-10 2012-05-10

Publications (1)

Publication Number Publication Date
SG10201807059QA true SG10201807059QA (en) 2018-09-27

Family

ID=49548780

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201406769RA SG11201406769RA (en) 2012-05-10 2013-03-14 Agents for influenza neutralization
SG10201807059QA SG10201807059QA (en) 2012-05-10 2013-03-14 Agents for influenza neutralization

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201406769RA SG11201406769RA (en) 2012-05-10 2013-03-14 Agents for influenza neutralization

Country Status (14)

Country Link
US (4) US9683030B2 (en)
EP (2) EP2846833A4 (en)
JP (2) JP6431477B2 (en)
KR (1) KR102122618B1 (en)
CN (2) CN104507500A (en)
AU (2) AU2013260123A1 (en)
BR (1) BR112014027991A2 (en)
CA (1) CA2871160C (en)
CL (1) CL2014003052A1 (en)
HK (1) HK1207970A1 (en)
IL (1) IL235237A0 (en)
MX (1) MX2014013678A (en)
SG (2) SG11201406769RA (en)
WO (1) WO2013169377A1 (en)

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SG10202103618XA (en) 2015-02-05 2021-05-28 Janssen Vaccines & Prevention Bv Binding molecules directed against influenza hemagglutinin and uses thereof
KR20180002713A (en) * 2015-05-11 2018-01-08 얀센 백신스 앤드 프리벤션 비.브이. Influenza virus neutralizing peptide mimic compound
EP3374390A1 (en) 2015-11-13 2018-09-19 Visterra, Inc. Compositions and methods for treating and preventing influenza
CN109195629A (en) 2016-02-24 2019-01-11 威特拉公司 Influenza antibody molecular preparation
KR101887876B1 (en) * 2016-08-18 2018-08-13 한국과학기술연구원 Nucleic acid aptamer specifically binding to H5 subtype avian influenza virus and Diagnosis method of H5 subtype avian influenza virus using the same
JP2022521819A (en) 2019-03-25 2022-04-12 ビステラ， インコーポレイテッド Compositions and Methods for Treating and Preventing Influenza
US20230257449A1 (en) 2019-12-11 2023-08-17 Visterra, Inc. Compositions and methods for treating and preventing influenza

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Also Published As

Publication number Publication date
US20200123234A1 (en) 2020-04-23
BR112014027991A2 (en) 2017-07-18
HK1207970A1 (en) 2016-02-19
CA2871160C (en) 2023-03-14
US20190062407A1 (en) 2019-02-28
US20130302348A1 (en) 2013-11-14
US9982037B2 (en) 2018-05-29
JP6431477B2 (en) 2018-12-05
CA2871160A1 (en) 2013-11-14
IL235237A0 (en) 2014-12-31
CN104507500A (en) 2015-04-08
AU2013260123A1 (en) 2014-11-13
KR102122618B1 (en) 2020-06-29
AU2018202468B2 (en) 2020-04-16
EP3492101A3 (en) 2019-10-23
AU2018202468A1 (en) 2018-04-26
EP2846833A4 (en) 2016-01-06
US10947300B2 (en) 2021-03-16
US9683030B2 (en) 2017-06-20
US10538578B2 (en) 2020-01-21
WO2013169377A1 (en) 2013-11-14
CL2014003052A1 (en) 2015-06-26
JP2018118991A (en) 2018-08-02
CN109265541A (en) 2019-01-25
US20170306003A1 (en) 2017-10-26
MX2014013678A (en) 2015-02-04
EP3492101A2 (en) 2019-06-05
SG11201406769RA (en) 2014-11-27
EP2846833A1 (en) 2015-03-18
JP2015517492A (en) 2015-06-22
KR20150008180A (en) 2015-01-21

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