MX378749B - Agentes para neutralizacion de influenza. - Google Patents

Agentes para neutralizacion de influenza.

Info

Publication number
MX378749B
MX378749B MX2014013678A MX2014013678A MX378749B MX 378749 B MX378749 B MX 378749B MX 2014013678 A MX2014013678 A MX 2014013678A MX 2014013678 A MX2014013678 A MX 2014013678A MX 378749 B MX378749 B MX 378749B
Authority
MX
Mexico
Prior art keywords
antibodies
agents
influenza
influenza neutralization
neutralization
Prior art date
Application number
MX2014013678A
Other languages
English (en)
Other versions
MX2014013678A (es
Inventor
Kannan Tharakaraman
Ram Sasisekharan
S Raguram
Venkataramanan Soundararajan
Vidya Subramanian
Viswanathan Sasisekharan
Original Assignee
Massachussetts Institute Of Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachussetts Institute Of Tech filed Critical Massachussetts Institute Of Tech
Publication of MX2014013678A publication Critical patent/MX2014013678A/es
Publication of MX378749B publication Critical patent/MX378749B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/108—Orthomyxoviridae (F), e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a anticuerpos (p. ej., anticuerpos monoclonales, anticuerpos humanos, anticuerpos humanizados, etc.), que se unen a múltiples cepas de influenza. Los anticuerpos son útiles, por ejemplo, en la profilaxis, el tratamiento, el diagnóstico y/o el estudio de la influenza.
MX2014013678A 2012-05-10 2013-03-14 Agentes para neutralizacion de influenza. MX378749B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261645453P 2012-05-10 2012-05-10
PCT/US2013/031704 WO2013169377A1 (en) 2012-05-10 2013-03-14 Agents for influenza neutralization

Publications (2)

Publication Number Publication Date
MX2014013678A MX2014013678A (es) 2015-02-04
MX378749B true MX378749B (es) 2025-03-10

Family

ID=49548780

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014013678A MX378749B (es) 2012-05-10 2013-03-14 Agentes para neutralizacion de influenza.

Country Status (14)

Country Link
US (4) US9683030B2 (es)
EP (2) EP3492101A3 (es)
JP (2) JP6431477B2 (es)
KR (1) KR102122618B1 (es)
CN (2) CN109265541A (es)
AU (2) AU2013260123A1 (es)
BR (1) BR112014027991A2 (es)
CA (1) CA2871160C (es)
CL (1) CL2014003052A1 (es)
HK (1) HK1207970A1 (es)
IL (1) IL235237A0 (es)
MX (1) MX378749B (es)
SG (2) SG10201807059QA (es)
WO (1) WO2013169377A1 (es)

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WO2013169377A1 (en) 2012-05-10 2013-11-14 Massachusetts Institute Of Technology Agents for influenza neutralization
TWI702229B (zh) 2014-12-19 2020-08-21 美商再生元醫藥公司 流行性感冒病毒血球凝集素之人類抗體
PH12017501216B1 (en) 2015-02-05 2023-05-24 Janssen Vaccines And Prevention B V Binding molecules directed against influenza hemagglutinin and uses thereof
MX386783B (es) * 2015-05-11 2025-03-19 Janssen Vaccines & Prevention Bv Compuestos peptidomiméticos que neutralizan el virus influenza.
WO2017083627A1 (en) 2015-11-13 2017-05-18 Visterra, Inc. Compositions and methods for treating and preventing influenza
EP3419663A1 (en) 2016-02-24 2019-01-02 Visterra, Inc. Formulations of antibody molecules to influenza virus
KR101887876B1 (ko) 2016-08-18 2018-08-13 한국과학기술연구원 H5형 조류독감 바이러스에 특이적으로 결합하는 핵산 압타머 및 이를 이용하는 h5형 조류독감 바이러스의 검출방법
CN113924147A (zh) 2019-03-25 2022-01-11 威特拉公司 用于治疗和预防流感的组合物和方法
WO2021119467A1 (en) 2019-12-11 2021-06-17 Visterra, Inc. Compositions and methods for treating and preventing influenza

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Also Published As

Publication number Publication date
CN104507500A (zh) 2015-04-08
US10947300B2 (en) 2021-03-16
US10538578B2 (en) 2020-01-21
SG10201807059QA (en) 2018-09-27
JP2015517492A (ja) 2015-06-22
HK1207970A1 (en) 2016-02-19
US9982037B2 (en) 2018-05-29
US20130302348A1 (en) 2013-11-14
MX2014013678A (es) 2015-02-04
CA2871160A1 (en) 2013-11-14
WO2013169377A1 (en) 2013-11-14
CN109265541A (zh) 2019-01-25
IL235237A0 (en) 2014-12-31
CL2014003052A1 (es) 2015-06-26
AU2013260123A1 (en) 2014-11-13
EP2846833A4 (en) 2016-01-06
US20170306003A1 (en) 2017-10-26
CA2871160C (en) 2023-03-14
US9683030B2 (en) 2017-06-20
EP3492101A2 (en) 2019-06-05
KR20150008180A (ko) 2015-01-21
JP6431477B2 (ja) 2018-12-05
SG11201406769RA (en) 2014-11-27
JP2018118991A (ja) 2018-08-02
BR112014027991A2 (pt) 2017-07-18
KR102122618B1 (ko) 2020-06-29
US20200123234A1 (en) 2020-04-23
AU2018202468B2 (en) 2020-04-16
AU2018202468A1 (en) 2018-04-26
EP3492101A3 (en) 2019-10-23
EP2846833A1 (en) 2015-03-18
US20190062407A1 (en) 2019-02-28

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