CL2014001559A1 - Sistema terapeutico transdermico que comprende una estructura de capa autoadhesiva que contiene buprenorfina la cual comprende a) una capa de respaldo impermeable a buprenorfina y b) una capa adhesiva sensible a la presion que contiene buprenorfina, la cual contacta la piel y que comprende al menos un adhesivo, buprenorfina y un acido carboxilico; su metodo de fabricacion, util para tratar el dolor. - Google Patents
Sistema terapeutico transdermico que comprende una estructura de capa autoadhesiva que contiene buprenorfina la cual comprende a) una capa de respaldo impermeable a buprenorfina y b) una capa adhesiva sensible a la presion que contiene buprenorfina, la cual contacta la piel y que comprende al menos un adhesivo, buprenorfina y un acido carboxilico; su metodo de fabricacion, util para tratar el dolor.Info
- Publication number
- CL2014001559A1 CL2014001559A1 CL2014001559A CL2014001559A CL2014001559A1 CL 2014001559 A1 CL2014001559 A1 CL 2014001559A1 CL 2014001559 A CL2014001559 A CL 2014001559A CL 2014001559 A CL2014001559 A CL 2014001559A CL 2014001559 A1 CL2014001559 A1 CL 2014001559A1
- Authority
- CL
- Chile
- Prior art keywords
- buprenorphine
- adhesive layer
- skin
- contacts
- self
- Prior art date
Links
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 title 4
- 229960001736 buprenorphine Drugs 0.000 title 4
- 239000010410 layer Substances 0.000 title 2
- 239000004820 Pressure-sensitive adhesive Substances 0.000 title 1
- 239000000853 adhesive Substances 0.000 title 1
- 230000001070 adhesive effect Effects 0.000 title 1
- 239000012790 adhesive layer Substances 0.000 title 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161569609P | 2011-12-12 | 2011-12-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014001559A1 true CL2014001559A1 (es) | 2014-10-03 |
Family
ID=47754872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014001559A CL2014001559A1 (es) | 2011-12-12 | 2014-06-12 | Sistema terapeutico transdermico que comprende una estructura de capa autoadhesiva que contiene buprenorfina la cual comprende a) una capa de respaldo impermeable a buprenorfina y b) una capa adhesiva sensible a la presion que contiene buprenorfina, la cual contacta la piel y que comprende al menos un adhesivo, buprenorfina y un acido carboxilico; su metodo de fabricacion, util para tratar el dolor. |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US20140363487A1 (OSRAM) |
| EP (1) | EP2790685B1 (OSRAM) |
| JP (2) | JP6289378B2 (OSRAM) |
| KR (1) | KR102014565B1 (OSRAM) |
| CN (2) | CN107669662A (OSRAM) |
| AP (1) | AP4036A (OSRAM) |
| AR (1) | AR089201A1 (OSRAM) |
| AU (1) | AU2012327247B2 (OSRAM) |
| BR (1) | BR112014014137A2 (OSRAM) |
| CA (1) | CA2858531C (OSRAM) |
| CL (1) | CL2014001559A1 (OSRAM) |
| CO (1) | CO7000779A2 (OSRAM) |
| CR (1) | CR20140321A (OSRAM) |
| DE (1) | DE112012005185T5 (OSRAM) |
| EA (1) | EA201491164A1 (OSRAM) |
| ES (1) | ES2647516T3 (OSRAM) |
| GB (1) | GB2512007B8 (OSRAM) |
| IL (1) | IL233025A0 (OSRAM) |
| MX (1) | MX352795B (OSRAM) |
| PE (1) | PE20142341A1 (OSRAM) |
| PH (1) | PH12014501231A1 (OSRAM) |
| PL (1) | PL2790685T3 (OSRAM) |
| SG (2) | SG11201403162XA (OSRAM) |
| TN (1) | TN2014000233A1 (OSRAM) |
| TW (1) | TW201338813A (OSRAM) |
| WO (1) | WO2013088254A1 (OSRAM) |
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| MX354603B (es) | 2007-05-25 | 2018-03-13 | Indivior Uk Ltd | Formulaciones de transferencia sostenida de compuestos de risperidona. |
| GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| CA2841785A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| WO2013086217A1 (en) | 2011-12-06 | 2013-06-13 | Masco Corporation Of Indiana | Ozone distribution in a faucet |
| TW201338813A (zh) | 2011-12-12 | 2013-10-01 | Lohmann Therapie Syst Lts | 經皮遞送系統 |
| WO2013126552A1 (en) * | 2012-02-21 | 2013-08-29 | Auburn University | Buprenorphine nanoparticle composition and methods thereof |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
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| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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| WO2015001012A1 (de) | 2013-07-03 | 2015-01-08 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches system mit elektronischem bauteil |
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| CA2948221C (en) | 2014-05-20 | 2022-11-22 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| CA2948220C (en) | 2014-05-20 | 2023-06-20 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
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| JP2021515791A (ja) | 2018-03-13 | 2021-06-24 | エルテーエス ローマン テラピー−ジステーメ アーゲー | シリコーンアクリルハイブリッドポリマーを含む経皮治療システム |
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| DE102004045599A1 (de) | 2004-09-17 | 2006-03-23 | Grünenthal GmbH | System zur sequentiellen, transdermalen Verabreichung von systemisch wirksamen Substanzen |
| DE102004062647A1 (de) | 2004-12-21 | 2006-06-29 | Kronotec Ag | Holzfaserdämmstoffplatte bzw.- matte |
| DE102004062614B4 (de) | 2004-12-24 | 2011-12-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung |
| DE102006054732B4 (de) | 2006-11-21 | 2010-12-30 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren |
| DE102006054731B4 (de) | 2006-11-21 | 2013-02-28 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie |
| EP2366388A1 (de) | 2010-03-17 | 2011-09-21 | Ratiopharm GmbH | Nicht-okklusives transdermales therapeutisches System zur Verabreichung von Buprenorphin |
| TW201338813A (zh) * | 2011-12-12 | 2013-10-01 | Lohmann Therapie Syst Lts | 經皮遞送系統 |
| AU2013205080B2 (en) | 2012-12-12 | 2016-07-07 | Lts Lohmann Therapie-Systeme Ag | Transdermal Delivery System |
| SG11201509218SA (en) | 2013-06-04 | 2015-12-30 | Lohmann Therapie Syst Lts | Transdermal delivery system |
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2012
- 2012-12-12 TW TW101146918A patent/TW201338813A/zh unknown
- 2012-12-12 AR ARP120104673A patent/AR089201A1/es unknown
- 2012-12-12 AU AU2012327247A patent/AU2012327247B2/en not_active Ceased
- 2012-12-12 PE PE2014000948A patent/PE20142341A1/es not_active Application Discontinuation
- 2012-12-12 PL PL12826670T patent/PL2790685T3/pl unknown
- 2012-12-12 CN CN201711075001.2A patent/CN107669662A/zh active Pending
- 2012-12-12 AP AP2014007779A patent/AP4036A/en active
- 2012-12-12 CN CN201280069476.XA patent/CN104114161A/zh active Pending
- 2012-12-12 SG SG11201403162XA patent/SG11201403162XA/en unknown
- 2012-12-12 ES ES12826670.7T patent/ES2647516T3/es active Active
- 2012-12-12 EA EA201491164A patent/EA201491164A1/ru unknown
- 2012-12-12 SG SG10201604754VA patent/SG10201604754VA/en unknown
- 2012-12-12 BR BR112014014137A patent/BR112014014137A2/pt not_active Application Discontinuation
- 2012-12-12 GB GB1412385.5A patent/GB2512007B8/en active Active
- 2012-12-12 MX MX2014007020A patent/MX352795B/es active IP Right Grant
- 2012-12-12 US US14/364,192 patent/US20140363487A1/en not_active Abandoned
- 2012-12-12 CA CA2858531A patent/CA2858531C/en active Active
- 2012-12-12 WO PCT/IB2012/002973 patent/WO2013088254A1/en not_active Ceased
- 2012-12-12 JP JP2014546672A patent/JP6289378B2/ja active Active
- 2012-12-12 DE DE112012005185.8T patent/DE112012005185T5/de not_active Ceased
- 2012-12-12 EP EP12826670.7A patent/EP2790685B1/en active Active
- 2012-12-12 KR KR1020147019186A patent/KR102014565B1/ko active Active
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2014
- 2014-05-28 TN TNP2014000233A patent/TN2014000233A1/en unknown
- 2014-05-30 PH PH12014501231A patent/PH12014501231A1/en unknown
- 2014-06-08 IL IL233025A patent/IL233025A0/en unknown
- 2014-06-12 CL CL2014001559A patent/CL2014001559A1/es unknown
- 2014-07-04 CR CR20140321A patent/CR20140321A/es unknown
- 2014-07-11 CO CO14149730A patent/CO7000779A2/es unknown
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2016
- 2016-01-11 US US14/992,122 patent/US9549903B2/en active Active
- 2016-10-07 JP JP2016198650A patent/JP2017036304A/ja active Pending
- 2016-10-10 US US15/289,507 patent/US20170049713A1/en not_active Abandoned
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2020
- 2020-01-31 US US16/778,920 patent/US20200306204A1/en not_active Abandoned
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