CL2014000159A1 - Copolimeros multibloque termoplasticos biodegradables para la liberacion controlada de compuestos biologicamente activos; proceso de preparacion de dicho copolimero; composicion para suministro de compuesto biologicamente activo a un hospedero; y metodo para suministrar dicho compuesto. - Google Patents
Copolimeros multibloque termoplasticos biodegradables para la liberacion controlada de compuestos biologicamente activos; proceso de preparacion de dicho copolimero; composicion para suministro de compuesto biologicamente activo a un hospedero; y metodo para suministrar dicho compuesto.Info
- Publication number
- CL2014000159A1 CL2014000159A1 CL2014000159A CL2014000159A CL2014000159A1 CL 2014000159 A1 CL2014000159 A1 CL 2014000159A1 CL 2014000159 A CL2014000159 A CL 2014000159A CL 2014000159 A CL2014000159 A CL 2014000159A CL 2014000159 A1 CL2014000159 A1 CL 2014000159A1
- Authority
- CL
- Chile
- Prior art keywords
- biologically active
- compound
- deliver
- copolymer
- host
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 3
- 238000000034 method Methods 0.000 title 2
- 238000013270 controlled release Methods 0.000 title 1
- 229920001577 copolymer Polymers 0.000 title 1
- 229920006030 multiblock copolymer Polymers 0.000 title 1
- 229920001169 thermoplastic Polymers 0.000 title 1
- 239000004416 thermosoftening plastic Substances 0.000 title 1
Classifications
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- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- Medicinal Chemistry (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11174987 | 2011-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014000159A1 true CL2014000159A1 (es) | 2014-08-29 |
Family
ID=46704994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014000159A CL2014000159A1 (es) | 2011-07-22 | 2014-01-21 | Copolimeros multibloque termoplasticos biodegradables para la liberacion controlada de compuestos biologicamente activos; proceso de preparacion de dicho copolimero; composicion para suministro de compuesto biologicamente activo a un hospedero; y metodo para suministrar dicho compuesto. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20140199385A1 (https=) |
| EP (1) | EP2734573B1 (https=) |
| JP (2) | JP6174023B2 (https=) |
| KR (1) | KR101889586B1 (https=) |
| CN (1) | CN103827177B (https=) |
| AU (1) | AU2012287577B2 (https=) |
| BR (1) | BR112014001441A2 (https=) |
| CA (1) | CA2842514C (https=) |
| CL (1) | CL2014000159A1 (https=) |
| CO (1) | CO7020923A2 (https=) |
| ES (1) | ES2899701T3 (https=) |
| IL (1) | IL230606B (https=) |
| MX (1) | MX362941B (https=) |
| MY (1) | MY169349A (https=) |
| PH (1) | PH12014500192A1 (https=) |
| RU (2) | RU2018125698A (https=) |
| UA (1) | UA112192C2 (https=) |
| WO (1) | WO2013015685A1 (https=) |
| ZA (1) | ZA201400846B (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2018125698A (ru) * | 2011-07-22 | 2019-03-13 | Иннокор Текнолоджис Б.В. | Биоразлагаемые полукристаллические термопластичные мультиблочные сополимеры с разделенными фазами для контролируемого высвобождения биологически активных соединений |
| RU2694901C2 (ru) * | 2013-04-18 | 2019-07-18 | Шаньдун Луе Фармасьютикал Ко., Лтд | Фармацевтические композиции микросфер гозерелина с пролонгированным высвобождением |
| JO3394B1 (ar) | 2014-07-04 | 2019-10-20 | Osteo Pharma B V | تركيبات ومنتجات للاستعمال في علاج كسور وعيوب العظام |
| CN105273153A (zh) * | 2014-07-24 | 2016-01-27 | 允友成(宿迁)复合新材料有限公司 | 一种可降解生物基水性乳液及其制备方法 |
| CN105273154A (zh) * | 2014-07-24 | 2016-01-27 | 允友成(宿迁)复合新材料有限公司 | 一种可降解聚乳酸基水性乳液及其制备方法 |
| JP6910949B2 (ja) * | 2014-08-14 | 2021-07-28 | ブラウン ユニバーシティ | タンパク質を安定化させ、送達するための組成物 |
| EP3218022A1 (en) | 2014-11-14 | 2017-09-20 | University College Cork, National University Of Ireland | Delivery of igf-1 in myocardial infarction |
| KR102009972B1 (ko) * | 2015-11-25 | 2019-10-21 | 주식회사 엘지화학 | 양친성 고분자 |
| KR102001614B1 (ko) * | 2015-11-25 | 2019-07-18 | 주식회사 엘지화학 | 양친성 고분자 |
| JP7665280B2 (ja) | 2015-12-22 | 2025-04-21 | アクセス・バスキュラー・インコーポレイテッド | 高強度生体材 |
| CN105461884B (zh) * | 2015-12-22 | 2018-05-29 | 佛山市顺德区福利来酒店傢具有限公司 | 儿童抗菌耐划伤家具及其制备方法 |
| KR101913146B1 (ko) * | 2016-06-16 | 2018-11-01 | 주식회사 엘지화학 | 양친성 트리블록 고분자 |
| WO2017217813A1 (ko) * | 2016-06-16 | 2017-12-21 | 주식회사 엘지화학 | 양친성 고분자 |
| CN109312035B (zh) * | 2016-06-16 | 2021-07-30 | 株式会社Lg化学 | 两亲性聚合物 |
| MX391306B (es) | 2017-01-31 | 2025-03-21 | Veru Inc | COMPOSICIONES PARA LA LIBERACIÓN PROLONGADA DE ANTAGONISTAS DE LA HORMONA LIBERADORA DE GONADOTROPINA (GnRH) |
| CN109876191B (zh) * | 2017-07-15 | 2020-04-03 | 深圳市立心科学有限公司 | 可吸收的生物医用复合材料及其制备方法 |
| CN111372970A (zh) | 2017-10-04 | 2020-07-03 | 时尚化学品股份有限公司 | 新的聚乳酸酯及其组合物 |
| WO2019187569A1 (ja) * | 2018-03-30 | 2019-10-03 | 東レ株式会社 | 生分解性を有するブロック共重合体 |
| CN108387664B (zh) * | 2018-07-03 | 2020-06-23 | 中国食品药品检定研究院 | 人血白蛋白分子大小分布超高效液相色谱测定方法 |
| WO2020071912A1 (en) | 2018-10-02 | 2020-04-09 | Innocore Technologies B.V. | Extended release formulations of human chorionic gonadotropin (hcg) |
| MY203238A (en) | 2018-10-29 | 2024-06-19 | Fraunhofer Ges Zur Frderung Der Angewandten Forschung E V | Tetracycline complexes with sustained activity |
| JP2022514368A (ja) * | 2018-12-19 | 2022-02-10 | アクセス・バスキュラー・インコーポレイテッド | 放出制御用高強度多孔質材料 |
| EA202192644A1 (ru) * | 2019-03-28 | 2021-12-14 | Пк Мед | Многокомпонентный термопластичный продукт |
| US20210017329A1 (en) * | 2019-07-19 | 2021-01-21 | Evonik Operations Gmbh | Multi-block shape memory bioresorbable polymers |
| CA3156256A1 (en) * | 2019-10-01 | 2021-04-08 | InnoCore Technologies Holding B.V. | Biodegradable, phase separated, thermoplastic multi-block copolymer |
| WO2021067388A1 (en) | 2019-10-01 | 2021-04-08 | Allergan Sales, Llc | Poly-dioxanone multi-block copolymer for ocular protein delivery |
| US11819576B2 (en) * | 2019-10-31 | 2023-11-21 | Evonik Operations Gmbh | Process for preparing nano-or microparticles comprising a carrier-polymer and one or more biologically active ingredients |
| US20220409730A1 (en) * | 2019-11-01 | 2022-12-29 | InnoCore Technologies Holding B.V. | Dosage form for extended release of an antibody or large protein |
| US20230055790A1 (en) * | 2019-12-12 | 2023-02-23 | Massachusetts Eye And Ear Infirmary | Melt-extrudable 3d printing inks |
| WO2021168170A1 (en) * | 2020-02-21 | 2021-08-26 | Natureworks Llc | Cosmetic compositions containing low molecular weight amorphous grade polylactic acid resin |
| CN115605248A (zh) | 2020-03-06 | 2023-01-13 | 阿塞斯血管有限公司(Us) | 用于水合制品的包装和相关方法 |
| JP2023522134A (ja) * | 2020-04-10 | 2023-05-26 | サイエンチュア, インコーポレイテッド | 長時間作用型アポモルフィン製剤、およびその治療送達用のインジェクター |
| US20240033221A1 (en) | 2020-04-22 | 2024-02-01 | Scienture, Inc. | Long-acting bupivacaine microsphere formulations |
| CN111484635B (zh) * | 2020-06-10 | 2023-09-12 | 杭州铭善生物科技有限公司 | 一种温敏性水凝胶材料的改性方法、改性温敏性水凝胶材料和生物3d打印墨水 |
| CN112336689B (zh) * | 2020-10-30 | 2022-06-28 | 浙江大学衢州研究院 | 一种结晶性嵌段共聚物胶束制备多重Pickering乳液的方法 |
| US20240082167A1 (en) * | 2021-01-22 | 2024-03-14 | University Of Connecticut | Synthetic artificial stem cells (sasc) |
| US12186722B2 (en) | 2022-02-07 | 2025-01-07 | Honeywell Federal Manufacturing & Technologies, Llc | Porous polysiloxane microspheres |
| CN114737276B (zh) * | 2022-03-11 | 2023-02-07 | 北京朗净汇明生物科技有限公司 | 一种耐热抗水解型聚乳酸纤维及其制备方法 |
| AU2023235001A1 (en) | 2022-03-17 | 2024-10-17 | InnoCore Technologies Holding B.V. | Biodegradable thermoplastic poly(ortho ester) based multiblock copolymers |
| WO2026015019A1 (en) | 2024-07-08 | 2026-01-15 | InnoCore Technologies Holding B.V. | Biodegradable thermoplastic polyoxazoline based copolymers |
| US12514756B1 (en) | 2024-10-08 | 2026-01-06 | Covidien Lp | Dermal patch and systems, kits, and methods associated therewith |
| DE102024129442A1 (de) | 2024-10-11 | 2026-04-16 | Universität Potsdam, Körperschaft des öffentlichen Rechts | Polymer-gekoppelte antikörper und antikörperfragmente |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4429080A (en) | 1982-07-01 | 1984-01-31 | American Cyanamid Company | Synthetic copolymer surgical articles and method of manufacturing the same |
| US5066772A (en) | 1987-12-17 | 1991-11-19 | Allied-Signal Inc. | Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides |
| US5133739A (en) | 1990-02-06 | 1992-07-28 | Ethicon, Inc. | Segmented copolymers of ε-caprolactone and glycolide |
| CN1037612C (zh) * | 1992-07-20 | 1998-03-04 | 中国科学院化学研究所 | 热致形状可回复性多嵌段聚合物材料 |
| US5236444A (en) | 1992-10-27 | 1993-08-17 | United States Surgical Corporation | Absorbable polymers and surgical articles made therefrom |
| NZ261250A (en) * | 1993-01-06 | 1997-08-22 | Kinerton Ltd | Ionic conjugates of polypeptides |
| US5403347A (en) | 1993-05-27 | 1995-04-04 | United States Surgical Corporation | Absorbable block copolymers and surgical articles fabricated therefrom |
| US5711958A (en) | 1996-07-11 | 1998-01-27 | Life Medical Sciences, Inc. | Methods for reducing or eliminating post-surgical adhesion formation |
| US5980948A (en) | 1996-08-16 | 1999-11-09 | Osteotech, Inc. | Polyetherester copolymers as drug delivery matrices |
| US6211249B1 (en) | 1997-07-11 | 2001-04-03 | Life Medical Sciences, Inc. | Polyester polyether block copolymers |
| US6160084A (en) | 1998-02-23 | 2000-12-12 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
| US8158143B2 (en) | 2000-07-14 | 2012-04-17 | Helmholtz-Zentrum Geesthacht Zentrum Fuer Material- Und Kuestenforschung Gmbh | Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect |
| EP1382628A1 (en) * | 2002-07-16 | 2004-01-21 | Polyganics B.V. | Biodegradable phase separated segmented/block co-polyesters |
| EP1555278A1 (en) * | 2004-01-15 | 2005-07-20 | Innocore Technologies B.V. | Biodegradable multi-block co-polymers |
| US20090004243A1 (en) * | 2007-06-29 | 2009-01-01 | Pacetti Stephen D | Biodegradable triblock copolymers for implantable devices |
| RU2018125698A (ru) * | 2011-07-22 | 2019-03-13 | Иннокор Текнолоджис Б.В. | Биоразлагаемые полукристаллические термопластичные мультиблочные сополимеры с разделенными фазами для контролируемого высвобождения биологически активных соединений |
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2012
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- 2012-07-23 BR BR112014001441A patent/BR112014001441A2/pt not_active Application Discontinuation
- 2012-07-23 CN CN201280040941.7A patent/CN103827177B/zh active Active
- 2012-07-23 US US14/233,961 patent/US20140199385A1/en not_active Abandoned
- 2012-07-23 WO PCT/NL2012/050529 patent/WO2013015685A1/en not_active Ceased
- 2012-07-23 PH PH1/2014/500192A patent/PH12014500192A1/en unknown
- 2012-07-23 MX MX2014000891A patent/MX362941B/es active IP Right Grant
- 2012-07-23 AU AU2012287577A patent/AU2012287577B2/en active Active
- 2012-07-23 EP EP12748568.8A patent/EP2734573B1/en active Active
- 2012-07-23 RU RU2014102900A patent/RU2662818C2/ru active
- 2012-07-23 UA UAA201401832A patent/UA112192C2/uk unknown
- 2012-07-23 ES ES12748568T patent/ES2899701T3/es active Active
- 2012-07-23 MY MYPI2014700136A patent/MY169349A/en unknown
- 2012-07-23 CA CA2842514A patent/CA2842514C/en active Active
- 2012-07-23 KR KR1020147004468A patent/KR101889586B1/ko not_active Expired - Fee Related
- 2012-07-23 JP JP2014521586A patent/JP6174023B2/ja active Active
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- 2014-01-23 CO CO14012995A patent/CO7020923A2/es unknown
- 2014-02-04 ZA ZA2014/00846A patent/ZA201400846B/en unknown
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2017
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- 2017-08-15 US US15/677,442 patent/US10300019B2/en active Active
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| MY169349A (en) | 2019-03-21 |
| BR112014001441A2 (pt) | 2019-05-14 |
| RU2018125698A (ru) | 2019-03-13 |
| UA112192C2 (uk) | 2016-08-10 |
| ZA201400846B (en) | 2016-08-31 |
| PH12014500192A1 (en) | 2014-03-24 |
| JP2017141477A (ja) | 2017-08-17 |
| ES2899701T3 (es) | 2022-03-14 |
| CN103827177A (zh) | 2014-05-28 |
| MX362941B (es) | 2019-02-27 |
| US20180085318A1 (en) | 2018-03-29 |
| US10300019B2 (en) | 2019-05-28 |
| JP6174023B2 (ja) | 2017-08-02 |
| JP6472836B2 (ja) | 2019-02-20 |
| AU2012287577B2 (en) | 2017-02-16 |
| IL230606A0 (en) | 2014-03-31 |
| NZ620392A (en) | 2016-02-26 |
| CN103827177B (zh) | 2016-02-10 |
| EP2734573A1 (en) | 2014-05-28 |
| EP2734573B1 (en) | 2021-09-08 |
| CA2842514C (en) | 2018-12-18 |
| CA2842514A1 (en) | 2013-01-31 |
| US20140199385A1 (en) | 2014-07-17 |
| RU2014102900A (ru) | 2015-08-27 |
| AU2012287577A1 (en) | 2014-03-13 |
| RU2662818C2 (ru) | 2018-07-31 |
| CO7020923A2 (es) | 2014-08-11 |
| KR101889586B1 (ko) | 2018-09-20 |
| IL230606B (en) | 2019-07-31 |
| MX2014000891A (es) | 2015-05-11 |
| KR20140048296A (ko) | 2014-04-23 |
| JP2014521762A (ja) | 2014-08-28 |
| WO2013015685A1 (en) | 2013-01-31 |
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