CL2013002593A1 - Forma cristalina a1 de la sal clorhidrato del compuesto 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-piperidin-2,6-diona; composicion farmaceutica que la comprende; y su uso para tratar o prevenir una enfermedad o trastorno tal como cancer, angiogenesis, dolor, trastorno pulmonar y un trastorno del snc. - Google Patents
Forma cristalina a1 de la sal clorhidrato del compuesto 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-piperidin-2,6-diona; composicion farmaceutica que la comprende; y su uso para tratar o prevenir una enfermedad o trastorno tal como cancer, angiogenesis, dolor, trastorno pulmonar y un trastorno del snc.Info
- Publication number
- CL2013002593A1 CL2013002593A1 CL2013002593A CL2013002593A CL2013002593A1 CL 2013002593 A1 CL2013002593 A1 CL 2013002593A1 CL 2013002593 A CL2013002593 A CL 2013002593A CL 2013002593 A CL2013002593 A CL 2013002593A CL 2013002593 A1 CL2013002593 A1 CL 2013002593A1
- Authority
- CL
- Chile
- Prior art keywords
- disorder
- snc
- quinazolin
- piperidin
- dione
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161451806P | 2011-03-11 | 2011-03-11 |
Publications (1)
Publication Number | Publication Date |
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CL2013002593A1 true CL2013002593A1 (es) | 2014-01-31 |
Family
ID=45888486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2013002593A CL2013002593A1 (es) | 2011-03-11 | 2013-09-10 | Forma cristalina a1 de la sal clorhidrato del compuesto 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-piperidin-2,6-diona; composicion farmaceutica que la comprende; y su uso para tratar o prevenir una enfermedad o trastorno tal como cancer, angiogenesis, dolor, trastorno pulmonar y un trastorno del snc. |
Country Status (34)
Country | Link |
---|---|
US (5) | US8802685B2 (no) |
EP (2) | EP2683708B1 (no) |
JP (1) | JP5959543B2 (no) |
KR (1) | KR20140014221A (no) |
CN (2) | CN106083812A (no) |
AR (1) | AR085650A1 (no) |
AU (2) | AU2012229279B2 (no) |
BR (1) | BR112013023279A2 (no) |
CA (3) | CA3037184C (no) |
CL (1) | CL2013002593A1 (no) |
CO (1) | CO6821939A2 (no) |
CR (2) | CR20130458A (no) |
CY (1) | CY1119974T1 (no) |
DK (1) | DK2683708T3 (no) |
EA (1) | EA026100B1 (no) |
EC (1) | ECSP13012877A (no) |
ES (1) | ES2656855T3 (no) |
HR (1) | HRP20180133T1 (no) |
HU (1) | HUE037955T2 (no) |
LT (1) | LT2683708T (no) |
MX (1) | MX2013010360A (no) |
NI (1) | NI201300080A (no) |
NO (1) | NO2683708T3 (no) |
PE (1) | PE20140983A1 (no) |
PL (1) | PL2683708T3 (no) |
PT (1) | PT2683708T (no) |
RS (1) | RS56770B1 (no) |
RU (1) | RU2611007C2 (no) |
SG (1) | SG192946A1 (no) |
SI (1) | SI2683708T1 (no) |
TW (2) | TWI601722B (no) |
UA (1) | UA113512C2 (no) |
WO (1) | WO2012125438A1 (no) |
ZA (1) | ZA201306234B (no) |
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PL2683708T3 (pl) | 2011-03-11 | 2018-03-30 | Celgene Corporation | Postacie stałe 3-(5-amino-2-metylo-4-okso-4h-chinazolin-3-ylo)-piperydyno-2,6-dionu oraz ich kompozycje farmaceutyczne i zastosowania |
CA2867134C (en) | 2011-03-28 | 2019-05-07 | Sheila Dewitt | 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds |
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JP6359563B2 (ja) | 2013-01-14 | 2018-07-18 | デュートルクス・リミテッド・ライアビリティ・カンパニーDeuteRx, LLC | 3−(5置換−4−オキソキナゾリン−3(4h)−イル)−3−ジュウテロピペリジン−2,6−ジオン誘導体 |
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TW201642857A (zh) | 2015-04-06 | 2016-12-16 | 西建公司 | 以組合療法治療肝細胞癌 |
JP6727237B2 (ja) | 2015-07-02 | 2020-07-22 | セルジーン コーポレイション | 血液がん及び固形腫瘍の治療のための併用療法 |
US9809603B1 (en) | 2015-08-18 | 2017-11-07 | Deuterx, Llc | Deuterium-enriched isoindolinonyl-piperidinonyl conjugates and oxoquinazolin-3(4H)-yl-piperidinonyl conjugates and methods of treating medical disorders using same |
CA2996641A1 (en) * | 2015-08-27 | 2017-03-02 | Celgene Corporation | Pharmaceutical compositions comprising 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione |
AU2016364753A1 (en) | 2015-12-02 | 2018-06-14 | Celgene Corporation | Cycling therapy using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione |
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WO2017205622A1 (en) * | 2016-05-25 | 2017-11-30 | Savant Neglected Diseases, Llc | Method of making benznidazole |
US11401336B2 (en) | 2018-02-21 | 2022-08-02 | Celgene Corporation | BCMA-binding antibodies and uses thereof |
RU2695326C1 (ru) * | 2018-06-05 | 2019-07-23 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт биомедицинской химии имени В.Н. Ореховича" (ИБМХ) | Противоопухолевое средство для лечения рака предстательной железы в форме саше |
CN113484355B (zh) * | 2021-06-30 | 2023-03-17 | 中国科学院青海盐湖研究所 | 一种水合盐体系相变储能材料循环性能的测试方法及应用 |
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