CL2013002003A1 - Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc - Google Patents

Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc

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Publication number
CL2013002003A1
CL2013002003A1 CL2013002003A CL2013002003A CL2013002003A1 CL 2013002003 A1 CL2013002003 A1 CL 2013002003A1 CL 2013002003 A CL2013002003 A CL 2013002003A CL 2013002003 A CL2013002003 A CL 2013002003A CL 2013002003 A1 CL2013002003 A1 CL 2013002003A1
Authority
CL
Chile
Prior art keywords
pde2
triazolo
quinoxaline
cns
inhibitors
Prior art date
Application number
CL2013002003A
Other languages
English (en)
Spanish (es)
Inventor
Hans-Joachim Lankau
Barbara Langen
Norbert Hofgen
Hans Stange
Rita Dost
Ute Egerland
Christian Grunwald
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of CL2013002003A1 publication Critical patent/CL2013002003A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P25/36—Opioid-abuse
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Pain & Pain Management (AREA)
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  • Urology & Nephrology (AREA)
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CL2013002003A 2011-01-31 2013-07-08 Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc CL2013002003A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161437848P 2011-01-31 2011-01-31

Publications (1)

Publication Number Publication Date
CL2013002003A1 true CL2013002003A1 (es) 2013-12-06

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CL2013002003A CL2013002003A1 (es) 2011-01-31 2013-07-08 Compuestos derivados de 1, 2, 4-triazolo [4,3-a] quinoxalina, inhibidores de pde2 y/o 10; composicion farmaceutica que los comprende; combinacion farmaceutica; y su uso para en el trastamiento de enfermedades del snc

Country Status (25)

Country Link
US (1) US9540379B2 (cg-RX-API-DMAC7.html)
EP (1) EP2670754B1 (cg-RX-API-DMAC7.html)
JP (1) JP6027547B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140019342A (cg-RX-API-DMAC7.html)
CN (1) CN103459395A (cg-RX-API-DMAC7.html)
AR (1) AR085099A1 (cg-RX-API-DMAC7.html)
AU (1) AU2012213471B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013019354A2 (cg-RX-API-DMAC7.html)
CA (1) CA2824929A1 (cg-RX-API-DMAC7.html)
CL (1) CL2013002003A1 (cg-RX-API-DMAC7.html)
CO (1) CO6811848A2 (cg-RX-API-DMAC7.html)
EA (1) EA023792B1 (cg-RX-API-DMAC7.html)
EC (1) ECSP13012824A (cg-RX-API-DMAC7.html)
GE (1) GEP20156333B (cg-RX-API-DMAC7.html)
IL (1) IL226826A (cg-RX-API-DMAC7.html)
MA (1) MA34844B1 (cg-RX-API-DMAC7.html)
MX (1) MX2013008667A (cg-RX-API-DMAC7.html)
PE (1) PE20141023A1 (cg-RX-API-DMAC7.html)
PH (1) PH12013501355A1 (cg-RX-API-DMAC7.html)
SG (1) SG192210A1 (cg-RX-API-DMAC7.html)
TN (1) TN2013000325A1 (cg-RX-API-DMAC7.html)
TW (1) TWI535718B (cg-RX-API-DMAC7.html)
UA (1) UA111963C2 (cg-RX-API-DMAC7.html)
UY (1) UY33888A (cg-RX-API-DMAC7.html)
WO (1) WO2012104293A1 (cg-RX-API-DMAC7.html)

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CA2824929A1 (en) 2012-08-09
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