CL2009000406A1 - Compuestos derivados de pirrolo[2,3-b]pirazinas; y su uso en la enfermedad autoinmune, trastornos inflamatorios, trastornos proliferativos, cancer, mediados por inhibidores selectivos de la jak 3. - Google Patents
Compuestos derivados de pirrolo[2,3-b]pirazinas; y su uso en la enfermedad autoinmune, trastornos inflamatorios, trastornos proliferativos, cancer, mediados por inhibidores selectivos de la jak 3.Info
- Publication number
- CL2009000406A1 CL2009000406A1 CL2009000406A CL2009000406A CL2009000406A1 CL 2009000406 A1 CL2009000406 A1 CL 2009000406A1 CL 2009000406 A CL2009000406 A CL 2009000406A CL 2009000406 A CL2009000406 A CL 2009000406A CL 2009000406 A1 CL2009000406 A1 CL 2009000406A1
- Authority
- CL
- Chile
- Prior art keywords
- pyrazines
- pyrrolo
- mediated
- cancer
- jak
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Abstract
Compuestos derivados de pirrolo [2,3b]pirazinas; y su uso en la enfermedad autoinmune, trastornos inflamatorios, trastornos proliferativos, cáncer, mediados por inhibidores selectivos de la jak 3.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3103508P | 2008-02-25 | 2008-02-25 | |
US20572409P | 2009-01-22 | 2009-01-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2009000406A1 true CL2009000406A1 (es) | 2010-09-21 |
Family
ID=40514094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2009000406A CL2009000406A1 (es) | 2008-02-25 | 2009-02-23 | Compuestos derivados de pirrolo[2,3-b]pirazinas; y su uso en la enfermedad autoinmune, trastornos inflamatorios, trastornos proliferativos, cancer, mediados por inhibidores selectivos de la jak 3. |
Country Status (20)
Country | Link |
---|---|
US (1) | US7939531B2 (es) |
EP (1) | EP2247592B1 (es) |
JP (1) | JP5368485B2 (es) |
KR (1) | KR101261514B1 (es) |
CN (1) | CN101939324B (es) |
AR (1) | AR070468A1 (es) |
AT (1) | ATE522535T1 (es) |
AU (1) | AU2009218607B2 (es) |
BR (1) | BRPI0908494A2 (es) |
CA (1) | CA2713710A1 (es) |
CL (1) | CL2009000406A1 (es) |
DK (1) | DK2247592T3 (es) |
IL (1) | IL206358A0 (es) |
MX (1) | MX2010008198A (es) |
PE (1) | PE20091493A1 (es) |
PL (1) | PL2247592T3 (es) |
PT (1) | PT2247592E (es) |
RU (1) | RU2503676C2 (es) |
TW (1) | TWI380987B (es) |
WO (1) | WO2009106442A1 (es) |
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KR100415791B1 (ko) * | 1998-06-19 | 2004-01-24 | 화이자 프로덕츠 인코포레이티드 | 피롤로[2,3-디]피리미딘 화합물 |
CA2699568C (en) * | 1999-12-24 | 2013-03-12 | Aventis Pharma Limited | Azaindoles |
GB0115109D0 (en) * | 2001-06-21 | 2001-08-15 | Aventis Pharma Ltd | Chemical compounds |
JP2005534618A (ja) | 2002-03-28 | 2005-11-17 | エーザイ株式会社 | 神経変性疾患用の、c−junn−末端キナーゼ阻害剤としての7−アザインドール |
US20070066641A1 (en) * | 2003-12-19 | 2007-03-22 | Prabha Ibrahim | Compounds and methods for development of RET modulators |
CA2550361C (en) * | 2003-12-19 | 2014-04-29 | Prabha Ibrahim | Compounds and methods for development of ret modulators |
AU2005269387A1 (en) * | 2004-07-27 | 2006-02-09 | Sgx Pharmaceuticals, Inc. | Fused ring heterocycle kinase modulators |
US7626021B2 (en) * | 2004-07-27 | 2009-12-01 | Sgx Pharmaceuticals, Inc. | Fused ring heterocycle kinase modulators |
EP1814883A1 (en) * | 2004-11-22 | 2007-08-08 | Vertex Pharmaceuticals Incorporated | Bicyclic inhibitors or rho kinase |
US7456289B2 (en) * | 2004-12-31 | 2008-11-25 | National Health Research Institutes | Anti-tumor compounds |
WO2007015866A2 (en) * | 2005-07-20 | 2007-02-08 | Kalypsys, Inc. | Inhibitors of p38 kinase and methods of treating inflammatory disorders |
CL2007002617A1 (es) | 2006-09-11 | 2008-05-16 | Sanofi Aventis | Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto. |
WO2008063888A2 (en) * | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
PE20121126A1 (es) * | 2006-12-21 | 2012-08-24 | Plexxikon Inc | Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa |
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2009
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- 2009-02-16 RU RU2010139566/04A patent/RU2503676C2/ru not_active IP Right Cessation
- 2009-02-16 KR KR1020107018678A patent/KR101261514B1/ko not_active IP Right Cessation
- 2009-02-16 AU AU2009218607A patent/AU2009218607B2/en not_active Ceased
- 2009-02-16 PL PL09713736T patent/PL2247592T3/pl unknown
- 2009-02-16 WO PCT/EP2009/051757 patent/WO2009106442A1/en active Application Filing
- 2009-02-16 BR BRPI0908494-0A patent/BRPI0908494A2/pt not_active IP Right Cessation
- 2009-02-16 CA CA2713710A patent/CA2713710A1/en not_active Abandoned
- 2009-02-16 DK DK09713736.8T patent/DK2247592T3/da active
- 2009-02-16 JP JP2010548069A patent/JP5368485B2/ja not_active Expired - Fee Related
- 2009-02-16 AT AT09713736T patent/ATE522535T1/de active
- 2009-02-16 EP EP09713736A patent/EP2247592B1/en not_active Not-in-force
- 2009-02-16 CN CN200980104705.5A patent/CN101939324B/zh not_active Expired - Fee Related
- 2009-02-16 MX MX2010008198A patent/MX2010008198A/es active IP Right Grant
- 2009-02-20 US US12/378,978 patent/US7939531B2/en not_active Expired - Fee Related
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- 2009-02-23 AR ARP090100621A patent/AR070468A1/es unknown
- 2009-02-23 PE PE2009000259A patent/PE20091493A1/es not_active Application Discontinuation
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Also Published As
Publication number | Publication date |
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MX2010008198A (es) | 2010-08-23 |
JP5368485B2 (ja) | 2013-12-18 |
DK2247592T3 (da) | 2011-09-26 |
CN101939324A (zh) | 2011-01-05 |
CA2713710A1 (en) | 2009-09-03 |
JP2011513262A (ja) | 2011-04-28 |
TWI380987B (zh) | 2013-01-01 |
KR101261514B1 (ko) | 2013-05-07 |
IL206358A0 (en) | 2010-12-30 |
RU2010139566A (ru) | 2012-04-10 |
EP2247592A1 (en) | 2010-11-10 |
AU2009218607B2 (en) | 2014-02-13 |
AU2009218607A1 (en) | 2009-09-03 |
PE20091493A1 (es) | 2009-09-25 |
ATE522535T1 (de) | 2011-09-15 |
EP2247592B1 (en) | 2011-08-31 |
PL2247592T3 (pl) | 2012-01-31 |
KR20100114094A (ko) | 2010-10-22 |
PT2247592E (pt) | 2011-11-03 |
US7939531B2 (en) | 2011-05-10 |
RU2503676C2 (ru) | 2014-01-10 |
US20090215750A1 (en) | 2009-08-27 |
WO2009106442A1 (en) | 2009-09-03 |
TW200938547A (en) | 2009-09-16 |
BRPI0908494A2 (pt) | 2015-08-11 |
CN101939324B (zh) | 2014-10-15 |
AR070468A1 (es) | 2010-04-07 |
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