CH672315A5 - - Google Patents

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Publication number
CH672315A5
CH672315A5 CH1851/86A CH185186A CH672315A5 CH 672315 A5 CH672315 A5 CH 672315A5 CH 1851/86 A CH1851/86 A CH 1851/86A CH 185186 A CH185186 A CH 185186A CH 672315 A5 CH672315 A5 CH 672315A5
Authority
CH
Switzerland
Prior art keywords
proline
lower alkyl
alkyl
compound according
lower alkoxy
Prior art date
Application number
CH1851/86A
Other languages
German (de)
English (en)
Inventor
Shizuo Nakamura
Makoto Inoue
Masatoshi Inai
Yoshiaki Tsuda
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9080386A external-priority patent/JPH06104680B2/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of CH672315A5 publication Critical patent/CH672315A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1851/86A 1985-11-13 1986-05-06 CH672315A5 (en:Method)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP25434285 1985-11-13
JP25434185 1985-11-13
JP9080386A JPH06104680B2 (ja) 1985-11-13 1986-04-18 プロリン誘導体

Publications (1)

Publication Number Publication Date
CH672315A5 true CH672315A5 (en:Method) 1989-11-15

Family

ID=27306547

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1851/86A CH672315A5 (en:Method) 1985-11-13 1986-05-06

Country Status (5)

Country Link
US (1) US4886813A (en:Method)
CH (1) CH672315A5 (en:Method)
DE (1) DE3615512A1 (en:Method)
FR (1) FR2594831B1 (en:Method)
GB (1) GB2182938B (en:Method)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0662671B2 (ja) * 1986-01-17 1994-08-17 株式会社大塚製薬工場 プロリン誘導体
US5076973A (en) * 1988-10-24 1991-12-31 Arizona Board Of Regents Synthesis of dolastatin 3
US6362003B1 (en) 1992-02-24 2002-03-26 Coulter Corporation Hematological reference control composition containing leukocyte analogs, methods of making, and uses thereof
JP2002515050A (ja) * 1996-12-31 2002-05-21 ジーピーアイ エヌアイエル ホールディングス インコーポレイテッド ヘテロ環式チオエステルのｎ−結合尿素およびカルバメート
US5935989A (en) 1996-12-31 1999-08-10 Gpi Nil Holdings Inc. N-linked ureas and carbamates of heterocyclic thioesters
WO2006017455A2 (en) * 2004-08-04 2006-02-16 Merck & Co., Inc. Diastereoselective reductive amination process

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
DE19575012I2 (de) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
EP0079521A1 (en) * 1981-11-09 1983-05-25 Merck & Co. Inc. Process for preparation of carboxyalkyldipeptide derivatives
US4642355A (en) * 1984-02-24 1987-02-10 Otsuka Pharmaceutical Factory, Inc. Proline derivatives
JPS61115064A (ja) * 1984-11-08 1986-06-02 Otsuka Pharmaceut Factory Inc プロリン誘導体

Also Published As

Publication number Publication date
FR2594831A1 (fr) 1987-08-28
GB8610360D0 (en) 1986-06-04
GB2182938A (en) 1987-05-28
DE3615512A1 (de) 1987-05-14
GB2182938B (en) 1989-11-08
FR2594831B1 (fr) 1990-04-27
US4886813A (en) 1989-12-12

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Legal Events

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PL Patent ceased
PL Patent ceased