CH670642A5 - - Google Patents
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- Publication number
- CH670642A5 CH670642A5 CH167/86A CH16786A CH670642A5 CH 670642 A5 CH670642 A5 CH 670642A5 CH 167/86 A CH167/86 A CH 167/86A CH 16786 A CH16786 A CH 16786A CH 670642 A5 CH670642 A5 CH 670642A5
- Authority
- CH
- Switzerland
- Prior art keywords
- isoquinoline
- group
- methoxy
- phthalidyl
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims description 67
- -1 lipid peroxides Chemical class 0.000 claims description 50
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- IRGJVQIJENCTQF-UHFFFAOYSA-N tritoqualine Chemical group CN1CCC2=CC=3OCOC=3C(OC)=C2C1C1C2=C(OCC)C(OCC)=C(OCC)C(N)=C2C(=O)O1 IRGJVQIJENCTQF-UHFFFAOYSA-N 0.000 claims description 25
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- UWYZHKAOTLEWKK-UHFFFAOYSA-N tetrahydro-isoquinoline Natural products C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 description 1
- 125000005309 thioalkoxy group Chemical group 0.000 description 1
- JOQGJRQKCIJIDB-UHFFFAOYSA-N tin;hydrochloride Chemical compound Cl.[Sn] JOQGJRQKCIJIDB-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69230985A | 1985-01-17 | 1985-01-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH670642A5 true CH670642A5 (OSRAM) | 1989-06-30 |
Family
ID=24780061
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH2174/88A CH677731A5 (en) | 1985-01-17 | 1986-01-17 | Use of isoquinoline derivs. |
| CH167/86A CH670642A5 (OSRAM) | 1985-01-17 | 1986-01-17 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH2174/88A CH677731A5 (en) | 1985-01-17 | 1986-01-17 | Use of isoquinoline derivs. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0201359A3 (OSRAM) |
| JP (2) | JPS61165326A (OSRAM) |
| BE (1) | BE904059A (OSRAM) |
| CH (2) | CH677731A5 (OSRAM) |
| FR (1) | FR2578164B1 (OSRAM) |
| IT (1) | IT1213024B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63270678A (ja) * | 1987-04-30 | 1988-11-08 | Mitsui Petrochem Ind Ltd | 新規含窒素化合物 |
| US20050049278A1 (en) * | 2003-08-27 | 2005-03-03 | Youssef Bennani | Benzo[1,3]dioxole compounds, pharmaceutical compositions thereof, and processes of making and using the same |
| CN101735229A (zh) * | 2009-12-24 | 2010-06-16 | 沈阳药科大学 | 四氢异喹啉类化合物及其制备方法和用途 |
| FR3111071B1 (fr) * | 2020-06-04 | 2023-01-13 | H4 Orphan Pharma | Utilisation de ligands multifonctionnels pour traiter les syndromes de détresse respiratoire et le choc cytokinique liés aux infections virales à coronavirus. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1206909B (de) * | 1959-08-14 | 1965-12-16 | Maurice Jeanson | Verfahren zur Herstellung von Inhibitoren der Histidindecarboxylase |
| FR2424271A1 (fr) * | 1978-04-28 | 1979-11-23 | Laire Chimie Sa De | Derives de phtalidyl-isoquinoleines, leur preparation et leur application comme medicaments |
| DE2964836D1 (en) * | 1979-10-22 | 1983-03-24 | Calaire Chimie Sa | Phthalide-isoquinoline derivatives, their preparation and their use in medicaments |
-
1986
- 1986-01-14 JP JP61006118A patent/JPS61165326A/ja active Pending
- 1986-01-14 JP JP61006117A patent/JPS61165327A/ja active Pending
- 1986-01-17 CH CH2174/88A patent/CH677731A5/fr not_active IP Right Cessation
- 1986-01-17 EP EP86400095A patent/EP0201359A3/en not_active Withdrawn
- 1986-01-17 FR FR868600651A patent/FR2578164B1/fr not_active Expired - Lifetime
- 1986-01-17 IT IT8619100A patent/IT1213024B/it active
- 1986-01-17 CH CH167/86A patent/CH670642A5/fr not_active IP Right Cessation
- 1986-01-17 BE BE0/216148A patent/BE904059A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61165327A (ja) | 1986-07-26 |
| BE904059A (fr) | 1986-07-17 |
| FR2578164A1 (fr) | 1986-09-05 |
| JPS61165326A (ja) | 1986-07-26 |
| IT8619100A0 (it) | 1986-01-17 |
| IT1213024B (it) | 1989-12-07 |
| EP0201359A3 (en) | 1989-07-19 |
| CH677731A5 (en) | 1991-06-28 |
| FR2578164B1 (fr) | 1990-08-10 |
| EP0201359A2 (en) | 1986-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |