CH670631A5 - Prodn. of antiinflammatory 4-naphthyl-2-butanone deriv. - Google Patents

Prodn. of antiinflammatory 4-naphthyl-2-butanone deriv. Download PDF

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Publication number
CH670631A5
CH670631A5 CH54187A CH54187A CH670631A5 CH 670631 A5 CH670631 A5 CH 670631A5 CH 54187 A CH54187 A CH 54187A CH 54187 A CH54187 A CH 54187A CH 670631 A5 CH670631 A5 CH 670631A5
Authority
CH
Switzerland
Prior art keywords
formula
naphthyl
compound
hydrogenation
methoxy
Prior art date
Application number
CH54187A
Other languages
German (de)
English (en)
Inventor
Erol Ali Faruk
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of CH670631A5 publication Critical patent/CH670631A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH54187A 1986-02-15 1987-02-13 Prodn. of antiinflammatory 4-naphthyl-2-butanone deriv. CH670631A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868603766A GB8603766D0 (en) 1986-02-15 1986-02-15 Process

Publications (1)

Publication Number Publication Date
CH670631A5 true CH670631A5 (en) 1989-06-30

Family

ID=10593122

Family Applications (1)

Application Number Title Priority Date Filing Date
CH54187A CH670631A5 (en) 1986-02-15 1987-02-13 Prodn. of antiinflammatory 4-naphthyl-2-butanone deriv.

Country Status (8)

Country Link
JP (1) JPS62215545A (ja)
CH (1) CH670631A5 (ja)
DK (1) DK74987A (ja)
ES (1) ES2004876A6 (ja)
GB (1) GB8603766D0 (ja)
GR (1) GR870253B (ja)
NL (1) NL8700353A (ja)
SE (1) SE8700589L (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0792860A1 (en) * 1996-02-21 1997-09-03 ALFA CHEMICALS ITALIANA S.p.A. Process for the synthesis of nabumetone

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2014993B (en) * 1977-11-03 1982-05-12 Beecham Group Ltd Chemical compounds
US4221741A (en) * 1978-01-27 1980-09-09 Beecham Group Limited Preparation of 4(6'-methoxy-2'-naphthyl)butan-2-one

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0792860A1 (en) * 1996-02-21 1997-09-03 ALFA CHEMICALS ITALIANA S.p.A. Process for the synthesis of nabumetone

Also Published As

Publication number Publication date
SE8700589L (sv) 1987-08-16
JPS62215545A (ja) 1987-09-22
DK74987A (da) 1987-08-16
DK74987D0 (da) 1987-02-13
ES2004876A6 (es) 1989-02-16
NL8700353A (nl) 1987-09-01
GR870253B (en) 1987-06-16
GB8603766D0 (en) 1986-03-19
SE8700589D0 (sv) 1987-02-13

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Legal Events

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PL Patent ceased