NL8700353A - Nieuwe werkwijze. - Google Patents

Nieuwe werkwijze. Download PDF

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Publication number
NL8700353A
NL8700353A NL8700353A NL8700353A NL8700353A NL 8700353 A NL8700353 A NL 8700353A NL 8700353 A NL8700353 A NL 8700353A NL 8700353 A NL8700353 A NL 8700353A NL 8700353 A NL8700353 A NL 8700353A
Authority
NL
Netherlands
Prior art keywords
meo
formula
compound
process according
hydrogenation
Prior art date
Application number
NL8700353A
Other languages
English (en)
Dutch (nl)
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of NL8700353A publication Critical patent/NL8700353A/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8700353A 1986-02-15 1987-02-13 Nieuwe werkwijze. NL8700353A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868603766A GB8603766D0 (en) 1986-02-15 1986-02-15 Process
GB8603766 1986-02-15

Publications (1)

Publication Number Publication Date
NL8700353A true NL8700353A (nl) 1987-09-01

Family

ID=10593122

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8700353A NL8700353A (nl) 1986-02-15 1987-02-13 Nieuwe werkwijze.

Country Status (8)

Country Link
JP (1) JPS62215545A (ja)
CH (1) CH670631A5 (ja)
DK (1) DK74987A (ja)
ES (1) ES2004876A6 (ja)
GB (1) GB8603766D0 (ja)
GR (1) GR870253B (ja)
NL (1) NL8700353A (ja)
SE (1) SE8700589L (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0792860A1 (en) 1996-02-21 1997-09-03 ALFA CHEMICALS ITALIANA S.p.A. Process for the synthesis of nabumetone
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2407907A1 (fr) * 1977-11-03 1979-06-01 Beecham Group Ltd Derives du naphtalene utilisables comme medicament
EP0003643A1 (en) * 1978-01-27 1979-08-22 Beecham Group Plc Process for the preparation of 4-(6-methoxy-2-naphthyl)-butan-2-one; 4-(6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one and a process for its preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2407907A1 (fr) * 1977-11-03 1979-06-01 Beecham Group Ltd Derives du naphtalene utilisables comme medicament
EP0003643A1 (en) * 1978-01-27 1979-08-22 Beecham Group Plc Process for the preparation of 4-(6-methoxy-2-naphthyl)-butan-2-one; 4-(6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one and a process for its preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A.C.GOUDIE ET AL.: "4-(6-Methoxy-2-naphthyl)butan-2-one and Related Analogues, a Novel Structural Class of Antiinflammatory Compounds", JOURNAL OF MEDICINAL CHEMISTRY, vol. 21, no. 12, 1978, WASHINGTON US, pages 1260 - 1264, XP001024131, DOI: doi:10.1021/jm00210a016 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0792860A1 (en) 1996-02-21 1997-09-03 ALFA CHEMICALS ITALIANA S.p.A. Process for the synthesis of nabumetone
US5756851A (en) * 1996-10-21 1998-05-26 Albemarle Corporation Production of nabumetone or precursors thereof
US5907069A (en) * 1996-10-21 1999-05-25 Albemarle Corporation Production of nabumetone or precursors thereof

Also Published As

Publication number Publication date
SE8700589D0 (sv) 1987-02-13
GB8603766D0 (en) 1986-03-19
ES2004876A6 (es) 1989-02-16
GR870253B (en) 1987-06-16
DK74987A (da) 1987-08-16
SE8700589L (sv) 1987-08-16
JPS62215545A (ja) 1987-09-22
DK74987D0 (da) 1987-02-13
CH670631A5 (en) 1989-06-30

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