CH660304A5 - Antimykotische mittel mit hoher wirkstoff-freisetzung enthaltend bifonazol in form von loesung und spray. - Google Patents
Antimykotische mittel mit hoher wirkstoff-freisetzung enthaltend bifonazol in form von loesung und spray. Download PDFInfo
- Publication number
- CH660304A5 CH660304A5 CH1597/84A CH159784A CH660304A5 CH 660304 A5 CH660304 A5 CH 660304A5 CH 1597/84 A CH1597/84 A CH 1597/84A CH 159784 A CH159784 A CH 159784A CH 660304 A5 CH660304 A5 CH 660304A5
- Authority
- CH
- Switzerland
- Prior art keywords
- imidazole
- weight
- bifonazole
- diluent
- solution
- Prior art date
Links
- OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 title claims description 15
- 229960002206 bifonazole Drugs 0.000 title claims description 15
- 239000013543 active substance Substances 0.000 title claims description 6
- 239000003429 antifungal agent Substances 0.000 title claims 5
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims description 21
- 239000003795 chemical substances by application Substances 0.000 claims description 13
- 239000002904 solvent Substances 0.000 claims description 12
- 238000003892 spreading Methods 0.000 claims description 9
- 239000003085 diluting agent Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
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- 238000002360 preparation method Methods 0.000 claims description 7
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- 229940121375 antifungal agent Drugs 0.000 claims description 6
- FBAOVPVVMDOHPK-UHFFFAOYSA-N 2-(1h-imidazol-2-ylsulfinyl)-1h-imidazole Chemical compound N=1C=CNC=1S(=O)C1=NC=CN1 FBAOVPVVMDOHPK-UHFFFAOYSA-N 0.000 claims description 4
- YKFRUJSEPGHZFJ-UHFFFAOYSA-N N-trimethylsilylimidazole Chemical compound C[Si](C)(C)N1C=CN=C1 YKFRUJSEPGHZFJ-UHFFFAOYSA-N 0.000 claims description 4
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833311700 DE3311700A1 (de) | 1983-03-30 | 1983-03-30 | Antimykotische mittel mit hoher wirkstoff-freisetzung in form von loesung und spray |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH660304A5 true CH660304A5 (de) | 1987-04-15 |
Family
ID=6195161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1597/84A CH660304A5 (de) | 1983-03-30 | 1984-03-29 | Antimykotische mittel mit hoher wirkstoff-freisetzung enthaltend bifonazol in form von loesung und spray. |
Country Status (18)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2555555B2 (ja) * | 1991-07-03 | 1996-11-20 | 武田薬品工業株式会社 | 抗真菌性外用製剤 |
| US5246716A (en) * | 1992-01-10 | 1993-09-21 | W. Neudorff Gmbh Kg | Fatty acid-based antifungal composition having residual activity |
| DK0870497T3 (da) * | 1995-12-14 | 2004-05-24 | Taisho Pharmaceutical Co Ltd | Aerosolpræparat |
| RU2117473C1 (ru) * | 1996-05-28 | 1998-08-20 | Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии МЗ и ПМ РФ | Способ наружного лечения микозов стоп и гладкой кожи |
| JP5160018B2 (ja) | 2002-06-25 | 2013-03-13 | アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド | 非晶質医薬組成物を用いる経皮送達速度調節 |
| CN118615240B (zh) * | 2024-06-24 | 2024-12-27 | 江西普丽尔药业有限公司 | 一种联苯苄唑溶液剂及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2461406C2 (de) * | 1974-12-24 | 1984-06-14 | Bayer Ag, 5090 Leverkusen | Azolyl-(1)-methane und deren Salze, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
| JPS6018655B2 (ja) * | 1976-01-01 | 1985-05-11 | バイエル・アクチエンゲゼルシヤフト | アゾリル−（１）−メタン類及びそれらの塩 |
| JPS5598112A (en) * | 1979-01-17 | 1980-07-25 | Sumitomo Chem Co Ltd | Liquid medicine for external use |
| DE3019027A1 (de) * | 1980-05-19 | 1981-11-26 | Bayer Ag, 5090 Leverkusen | Antimikrobielle mittel |
| DE3045914A1 (de) * | 1980-12-05 | 1982-07-22 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern |
| DE3045915A1 (de) * | 1980-12-05 | 1982-07-08 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern |
| DE3045913A1 (de) * | 1980-12-05 | 1982-07-08 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel mit hoher wirkstoff-freisetzung |
| DE3106635A1 (de) * | 1981-02-23 | 1982-09-09 | Bayer Ag | Antimykotisches mittel mit hoher wirkstoff-freisetzung in form von stiften |
-
1983
- 1983-03-30 DE DE19833311700 patent/DE3311700A1/de not_active Withdrawn
-
1984
- 1984-03-22 ES ES530845A patent/ES530845A0/es active Granted
- 1984-03-26 PT PT78312A patent/PT78312B/pt unknown
- 1984-03-26 JP JP59056373A patent/JPS59184125A/ja active Pending
- 1984-03-27 IL IL71363A patent/IL71363A0/xx unknown
- 1984-03-28 GR GR74235A patent/GR81880B/el unknown
- 1984-03-28 LU LU85272A patent/LU85272A1/de unknown
- 1984-03-28 CA CA000450708A patent/CA1212328A/en not_active Expired
- 1984-03-28 PH PH30458A patent/PH20964A/en unknown
- 1984-03-29 GB GB08408066A patent/GB2137090B/en not_active Expired
- 1984-03-29 BE BE0/212652A patent/BE899277A/fr not_active IP Right Cessation
- 1984-03-29 AU AU26235/84A patent/AU564979B2/en not_active Expired
- 1984-03-29 SE SE8401747A patent/SE8401747L/ unknown
- 1984-03-29 CH CH1597/84A patent/CH660304A5/de not_active IP Right Cessation
- 1984-03-29 IT IT20304/84A patent/IT1173762B/it active
- 1984-03-29 ZA ZA842336A patent/ZA842336B/xx unknown
- 1984-03-29 FR FR8404907A patent/FR2543436B1/fr not_active Expired
- 1984-03-30 KR KR1019840001658A patent/KR840008283A/ko not_active Ceased
- 1984-12-31 ES ES539275A patent/ES8601691A1/es not_active Expired
- 1984-12-31 ES ES539274A patent/ES8601690A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT78312A (en) | 1984-04-01 |
| FR2543436B1 (fr) | 1988-12-16 |
| ES539274A0 (es) | 1985-11-16 |
| IT8420304A0 (it) | 1984-03-29 |
| DE3311700A1 (de) | 1984-10-04 |
| IL71363A0 (en) | 1984-06-29 |
| KR840008283A (ko) | 1984-12-14 |
| AU564979B2 (en) | 1987-09-03 |
| GB2137090B (en) | 1986-07-09 |
| BE899277A (fr) | 1984-10-01 |
| ES8503946A1 (es) | 1985-04-16 |
| SE8401747L (sv) | 1984-10-01 |
| GB2137090A (en) | 1984-10-03 |
| CA1212328A (en) | 1986-10-07 |
| FR2543436A1 (fr) | 1984-10-05 |
| SE8401747D0 (sv) | 1984-03-29 |
| PH20964A (en) | 1987-06-10 |
| JPS59184125A (ja) | 1984-10-19 |
| ZA842336B (en) | 1984-11-28 |
| IT1173762B (it) | 1987-06-24 |
| PT78312B (en) | 1986-06-02 |
| LU85272A1 (de) | 1984-11-14 |
| ES539275A0 (es) | 1985-11-16 |
| AU2623584A (en) | 1984-10-04 |
| ES8601691A1 (es) | 1985-11-16 |
| GR81880B (enrdf_load_stackoverflow) | 1984-12-12 |
| ES530845A0 (es) | 1985-04-16 |
| ES8601690A1 (es) | 1985-11-16 |
| GB8408066D0 (en) | 1984-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |