CH655724A5 - 1,2,8,8a-tetrahydro-cyclopropa(c)-benzo(1,2-b:-4,3-b')-dipyrol-4(5h)-on-verbindungen sowie ein verfahren zu ihrer herstellung. - Google Patents

1,2,8,8a-tetrahydro-cyclopropa(c)-benzo(1,2-b:-4,3-b')-dipyrol-4(5h)-on-verbindungen sowie ein verfahren zu ihrer herstellung. Download PDF

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Publication number
CH655724A5
CH655724A5 CH6895/81A CH689581A CH655724A5 CH 655724 A5 CH655724 A5 CH 655724A5 CH 6895/81 A CH6895/81 A CH 6895/81A CH 689581 A CH689581 A CH 689581A CH 655724 A5 CH655724 A5 CH 655724A5
Authority
CH
Switzerland
Prior art keywords
preparation
compound
formula
level
phenyl
Prior art date
Application number
CH6895/81A
Other languages
German (de)
English (en)
Inventor
Wendell Wierenga
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CH655724A5 publication Critical patent/CH655724A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CH6895/81A 1980-11-18 1981-10-28 1,2,8,8a-tetrahydro-cyclopropa(c)-benzo(1,2-b:-4,3-b')-dipyrol-4(5h)-on-verbindungen sowie ein verfahren zu ihrer herstellung. CH655724A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20783880A 1980-11-18 1980-11-18

Publications (1)

Publication Number Publication Date
CH655724A5 true CH655724A5 (de) 1986-05-15

Family

ID=22772188

Family Applications (2)

Application Number Title Priority Date Filing Date
CH4003/84A CH655726A5 (de) 1980-11-18 1981-10-28 1,2,8,8a-tetrahydro-cyclopropa(c)-benzo(1,2-b:-4,3-b')-dipyrrol-4(5h)-on-verbindungen sowie verfahren zur herstellung dieser verbindungen.
CH6895/81A CH655724A5 (de) 1980-11-18 1981-10-28 1,2,8,8a-tetrahydro-cyclopropa(c)-benzo(1,2-b:-4,3-b')-dipyrol-4(5h)-on-verbindungen sowie ein verfahren zu ihrer herstellung.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH4003/84A CH655726A5 (de) 1980-11-18 1981-10-28 1,2,8,8a-tetrahydro-cyclopropa(c)-benzo(1,2-b:-4,3-b')-dipyrrol-4(5h)-on-verbindungen sowie verfahren zur herstellung dieser verbindungen.

Country Status (8)

Country Link
JP (4) JPS57114589A (ja)
CH (2) CH655726A5 (ja)
DE (2) DE3142143A1 (ja)
FR (1) FR2494273B1 (ja)
GB (1) GB2087884B (ja)
HK (1) HK89990A (ja)
IT (1) IT1143242B (ja)
SU (1) SU1318165A3 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3300522A1 (de) * 1982-01-21 1983-07-28 Sandoz-Patent-GmbH, 7850 Lörrach 3,3-dialkyl- und 3,3-alkylen-indolinderivate, verfahren zu ihrer herstellung und pharmazeutische praeparate sie enthaltend
JP2598116B2 (ja) * 1988-12-28 1997-04-09 協和醗酵工業株式会社 新規物質ｄｃ１１３
JP4733303B2 (ja) * 2001-07-17 2011-07-27 株式会社日本製鋼所 テンタオーブン装置
JP2004278639A (ja) 2003-03-14 2004-10-07 Nabco Ltd 脈動吸収装置およびクラッチマスタシリンダ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169888A (en) 1977-10-17 1979-10-02 The Upjohn Company Composition of matter and process

Also Published As

Publication number Publication date
FR2494273B1 (fr) 1985-12-20
JPH0427231B2 (ja) 1992-05-11
JPH0314545A (ja) 1991-01-23
GB2087884A (en) 1982-06-03
DE3142143C2 (ja) 1992-07-30
JPH0310629B2 (ja) 1991-02-14
JPH0314581A (ja) 1991-01-23
JPH0465076B2 (ja) 1992-10-16
CH655726A5 (de) 1986-05-15
GB2087884B (en) 1985-06-05
SU1318165A3 (ru) 1987-06-15
FR2494273A1 (fr) 1982-05-21
JPH0460594B2 (ja) 1992-09-28
IT8149446A0 (it) 1981-10-07
DE3153725C2 (ja) 1993-03-18
IT1143242B (it) 1986-10-22
DE3142143A1 (de) 1982-06-24
JPS57114589A (en) 1982-07-16
JPH0314561A (ja) 1991-01-23
HK89990A (en) 1990-11-09

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Owner name: THE UPJOHN COMPANY TRANSFER- PHARMACIA & UPJOHN CO

PL Patent ceased