DE69005852T2 - Entzündungshemmende Benzoxazolone. - Google Patents

Entzündungshemmende Benzoxazolone.

Info

Publication number
DE69005852T2
DE69005852T2 DE90301941T DE69005852T DE69005852T2 DE 69005852 T2 DE69005852 T2 DE 69005852T2 DE 90301941 T DE90301941 T DE 90301941T DE 69005852 T DE69005852 T DE 69005852T DE 69005852 T2 DE69005852 T2 DE 69005852T2
Authority
DE
Germany
Prior art keywords
mammal
inflammatory
benzoxazolinones
compounds
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90301941T
Other languages
English (en)
Other versions
DE69005852D1 (de
Inventor
Kazuo Ando
Nobuko Asai
Fumitaka Ito
Takashi Mano
Masami Nakane
Kunio Satake
Kaoru Shimada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE69005852D1 publication Critical patent/DE69005852D1/de
Application granted granted Critical
Publication of DE69005852T2 publication Critical patent/DE69005852T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE90301941T 1989-02-28 1990-02-23 Entzündungshemmende Benzoxazolone. Expired - Fee Related DE69005852T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4742989 1989-02-28

Publications (2)

Publication Number Publication Date
DE69005852D1 DE69005852D1 (de) 1994-02-24
DE69005852T2 true DE69005852T2 (de) 1994-04-28

Family

ID=12774907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90301941T Expired - Fee Related DE69005852T2 (de) 1989-02-28 1990-02-23 Entzündungshemmende Benzoxazolone.

Country Status (24)

Country Link
US (1) US5086062A (de)
EP (1) EP0385664B1 (de)
JP (1) JPH0730053B2 (de)
KR (1) KR920010641B1 (de)
CN (1) CN1045264A (de)
AT (1) ATE100091T1 (de)
AU (1) AU617041B2 (de)
CA (1) CA2010765A1 (de)
DD (1) DD292256A5 (de)
DE (1) DE69005852T2 (de)
DK (1) DK0385664T3 (de)
ES (1) ES2062332T3 (de)
FI (1) FI900979A0 (de)
HU (1) HUT58328A (de)
IE (1) IE900695L (de)
IL (1) IL93473A0 (de)
MY (1) MY105263A (de)
NO (1) NO900915L (de)
NZ (1) NZ232707A (de)
PL (2) PL163419B1 (de)
PT (1) PT93257A (de)
RU (2) RU2036913C1 (de)
YU (1) YU37490A (de)
ZA (1) ZA901480B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0678327B2 (ja) * 1989-07-20 1994-10-05 ファイザー製薬株式会社 ４，５，６，７，―四置換ベンゾオキサゾロン類
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
DE10210779A1 (de) * 2002-03-12 2003-10-09 Merck Patent Gmbh Cyclische Amide
RU2477283C1 (ru) * 2012-02-27 2013-03-10 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) 4,7-ДИМЕТИЛ-2-(2,4,5-ТРИМЕТОКСИФЕНИЛ)-3,4,4a,5,8,8a-ГЕКСАГИДРО-2H-4,8-ЭПОКСИХРОМЕН, ОБЛАДАЮЩИЙ АНАЛЬГЕЗИРУЮЩЕЙ АКТИВНОСТЬЮ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3017977A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue substituierte 2(3h)-benzothiazolone
FR2491066A1 (fr) * 1980-09-29 1982-04-02 Cerm Cent Europ Rech Mauvernay Benzoxazolinones substituees en 6 par une chaine aminoalcool ou aminocetone, leur preparation et leur application en therapeutique
GB8325370D0 (en) * 1983-09-22 1983-10-26 Fujisawa Pharmaceutical Co Benzoxazoline and benzothiazoline derivatives
DK288287A (da) * 1986-06-09 1987-12-10 Pfizer Heterocycliske forbindelser samt farmaceutiske praeparater til behandling af allergiske eller inflammatoriske tilstande
US4835166A (en) * 1986-06-09 1989-05-30 Pfizer Inc. Antiallergy and antiinflammatory agents
JPH0283376A (ja) * 1988-09-19 1990-03-23 Pfizer Pharmaceut Co Ltd ベンゾオキサゾロン誘導体および抗アレルギー又は抗炎症組成物

Also Published As

Publication number Publication date
KR920010641B1 (ko) 1992-12-12
PL163378B1 (pl) 1994-03-31
FI900979A0 (fi) 1990-02-27
IL93473A0 (en) 1990-11-29
IE900695L (en) 1990-08-28
EP0385664A3 (de) 1991-03-06
NO900915D0 (no) 1990-02-27
PT93257A (pt) 1990-08-31
HU901063D0 (en) 1990-05-28
ES2062332T3 (es) 1994-12-16
PL288077A1 (en) 1991-12-02
JPH03218368A (ja) 1991-09-25
CN1045264A (zh) 1990-09-12
RU2024512C1 (ru) 1994-12-15
ATE100091T1 (de) 1994-01-15
DE69005852D1 (de) 1994-02-24
ZA901480B (en) 1991-10-30
PL163419B1 (pl) 1994-03-31
EP0385664A2 (de) 1990-09-05
CA2010765A1 (en) 1990-08-31
AU5056690A (en) 1990-09-06
KR910015571A (ko) 1991-09-30
MY105263A (en) 1994-09-30
YU37490A (en) 1992-05-28
US5086062A (en) 1992-02-04
DD292256A5 (de) 1991-07-25
PL284026A1 (en) 1991-04-08
DK0385664T3 (da) 1994-02-14
EP0385664B1 (de) 1994-01-12
HUT58328A (en) 1992-02-28
AU617041B2 (en) 1991-11-14
NZ232707A (en) 1991-01-29
RU2036913C1 (ru) 1995-06-09
JPH0730053B2 (ja) 1995-04-05
NO900915L (no) 1990-08-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee