CH652119A5 - Derives de l'acide guanidinocyclohexanecarboxylique et leur procede de fabrication. - Google Patents
Derives de l'acide guanidinocyclohexanecarboxylique et leur procede de fabrication. Download PDFInfo
- Publication number
- CH652119A5 CH652119A5 CH380/82A CH38082A CH652119A5 CH 652119 A5 CH652119 A5 CH 652119A5 CH 380/82 A CH380/82 A CH 380/82A CH 38082 A CH38082 A CH 38082A CH 652119 A5 CH652119 A5 CH 652119A5
- Authority
- CH
- Switzerland
- Prior art keywords
- trans
- hydrochloride
- mixture
- acid
- crystals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP728381A JPS57122059A (en) | 1981-01-22 | 1981-01-22 | Novel cyclohexanecarboxylic acid derivative and its preparation |
| JP728481A JPS57122061A (en) | 1981-01-22 | 1981-01-22 | Novel cyclohexanecarboxylic acid derivative and its preparation |
| JP728681A JPS57122060A (en) | 1981-01-22 | 1981-01-22 | Carboxylic acid ester and its preparation |
| JP1083281A JPS57126463A (en) | 1981-01-29 | 1981-01-29 | Novel carboxylic ester and its preparation |
| JP1083181A JPS57126462A (en) | 1981-01-29 | 1981-01-29 | Novel carboxylic ester and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH652119A5 true CH652119A5 (fr) | 1985-10-31 |
Family
ID=27518804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH380/82A CH652119A5 (fr) | 1981-01-22 | 1982-01-21 | Derives de l'acide guanidinocyclohexanecarboxylique et leur procede de fabrication. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4465851A (enExample) |
| KR (1) | KR880001104B1 (enExample) |
| BE (1) | BE891790A (enExample) |
| BR (1) | BR8200212A (enExample) |
| CA (1) | CA1180716A (enExample) |
| CH (1) | CH652119A5 (enExample) |
| DE (1) | DE3201817A1 (enExample) |
| FR (1) | FR2498183A1 (enExample) |
| IT (1) | IT1191163B (enExample) |
| NL (1) | NL8200110A (enExample) |
| SE (1) | SE455789B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0585130B1 (en) * | 1992-08-27 | 1998-01-28 | Shiseido Company Limited | External preparation for skin containing a depigmentation agent |
| EP0775692B1 (en) * | 1994-08-30 | 2000-12-06 | Teikoku Chemical Industry Co., Ltd. | Guanidinomethyl cyclohexane carboxylic ester derivative |
| AUPO227896A0 (en) * | 1996-09-13 | 1996-10-03 | Fujisawa Pharmaceutical Co., Ltd. | Novel compounds and their preparation |
| AP1224A (en) | 1998-03-19 | 2003-11-14 | Bristol Myers Squibb Co | Biphasic controlled release delivery system for high solubility pharmaceuticals and method. |
| GB9908410D0 (en) | 1999-04-13 | 1999-06-09 | Pfizer Ltd | Pyridines |
| CN103153288B (zh) | 2010-07-09 | 2017-02-15 | 詹姆斯·特林卡·格林 | 用于包括瑞格列净的短半衰期药物的组合立即/延迟释放递送系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3699149A (en) * | 1968-10-14 | 1972-10-17 | Daiichi Seiyaku Co | Phenyl esters of t-amcha |
| JPS5339419B2 (enExample) * | 1972-10-19 | 1978-10-21 | ||
| JPS5140075A (enExample) * | 1974-09-30 | 1976-04-03 | Tokyo Shibaura Electric Co | |
| JPS5645454A (en) * | 1979-09-20 | 1981-04-25 | Nippon Chemiphar Co Ltd | Cyclohexanecarboxylic acid derivative and its preparation |
| SE460667B (sv) * | 1979-09-20 | 1989-11-06 | Nippon Chemiphar Co | Cyklohexankarboxylsyraderivat, foerfarande foer framstaellning daerav samt naemnda derivat foer terapeutisk anvaendning |
-
1982
- 1982-01-04 US US06/336,707 patent/US4465851A/en not_active Expired - Lifetime
- 1982-01-13 BR BR8200212A patent/BR8200212A/pt unknown
- 1982-01-13 NL NL8200110A patent/NL8200110A/nl not_active Application Discontinuation
- 1982-01-15 BE BE0/207062A patent/BE891790A/fr not_active IP Right Cessation
- 1982-01-20 SE SE8200309A patent/SE455789B/sv not_active IP Right Cessation
- 1982-01-20 CA CA000394507A patent/CA1180716A/en not_active Expired
- 1982-01-21 DE DE19823201817 patent/DE3201817A1/de active Granted
- 1982-01-21 IT IT67060/82A patent/IT1191163B/it active
- 1982-01-21 CH CH380/82A patent/CH652119A5/fr not_active IP Right Cessation
- 1982-01-22 FR FR8201032A patent/FR2498183A1/fr active Granted
- 1982-01-22 KR KR8200269A patent/KR880001104B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2498183A1 (fr) | 1982-07-23 |
| IT8267060A1 (it) | 1983-07-21 |
| SE455789B (sv) | 1988-08-08 |
| BE891790A (fr) | 1982-04-30 |
| IT1191163B (it) | 1988-02-24 |
| CA1180716A (en) | 1985-01-08 |
| FR2498183B1 (enExample) | 1985-05-10 |
| SE8200309L (sv) | 1982-07-23 |
| KR880001104B1 (ko) | 1988-06-29 |
| DE3201817A1 (de) | 1982-08-19 |
| US4465851A (en) | 1984-08-14 |
| KR830009011A (ko) | 1983-12-17 |
| DE3201817C2 (enExample) | 1991-03-07 |
| BR8200212A (pt) | 1982-11-09 |
| IT8267060A0 (it) | 1982-01-21 |
| NL8200110A (nl) | 1982-08-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2793195B2 (ja) | ベンゾチアゾール誘導体 | |
| US4714762A (en) | Antiarteriosclerotic substituted benzimidazol-2-yl-and 3H-imidazo[4,5-b]pyridin-2-yl-phenoxy-alkanoic acids and salts and esters thereof | |
| EP0116948A2 (en) | (2-Oxo-1,2,3,5-tetrahydroimidazo-(2,1-b)quinazolinyl)-oxyalkyl-amides | |
| US6159988A (en) | Arylcycloalkyl derivatives, their production and their use | |
| EP0202164A1 (fr) | Dérivés de (benzoyl-4 pipéridino)-2 phenyl-1 alcanols, leur préparation et leur application en thérapeutique | |
| US5110831A (en) | Vinylogous hydroxamic acids and derivatives thereof as 5-lipoxygenase inhibitors | |
| JPH0383979A (ja) | 新規ベンゾピランおよびベンゾチオピラン誘導体 | |
| US4338330A (en) | Benzimidazole derivatives, their use, and compositions containing these derivatives | |
| EP0360685B1 (fr) | "[(diarylméthoxy) alcoyl] - 1 pyrrolidines et piperidines, procédés de préparation et médicaments les contenant" | |
| EP0709383B1 (fr) | Dérivés de la diosmétine, leur procédé de préparation et les compositions pharmaceutiques les contenant | |
| FR2623808A1 (fr) | Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent | |
| CH652119A5 (fr) | Derives de l'acide guanidinocyclohexanecarboxylique et leur procede de fabrication. | |
| US4435422A (en) | 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions | |
| US5151431A (en) | 4,5-dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives useful for treating hypertension or edema | |
| US4255575A (en) | 2-Hydroxy-5-(1-hydroxy-2-piperazinylethyl)-benzoic acid derivatives | |
| US5246951A (en) | New benzoselenazolinone compounds | |
| US4474977A (en) | Amino-alcohol derivatives | |
| FR2514003A1 (fr) | Nouvelles xanthines a activite pharmacologique, leur procede d'obtention, les compositions pharmaceutiques qui les contiennent et leur utilisation en medecine humaine | |
| CH633541A5 (en) | Pharmacologically active substituted 1,2,4-triazines and medicaments containing these triazines | |
| JPS6399057A (ja) | グリシン誘導体 | |
| EP0005091B1 (fr) | Nouvelles pipérazines monosubstituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant | |
| CH650254A5 (fr) | Quinolones, leurs procedes de preparation et compositions therapeutiques les contenant. | |
| EP0282390B1 (fr) | Nouveaux dérivés de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acétique et les compositions pharmaceutiques qui les contiennent | |
| JPS6183179A (ja) | 新規フラボン誘導体 | |
| CA2439730A1 (en) | Benzofuran derivatives and pharmaceutical compositions containing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |