CH648327A5 - Anthracycline. - Google Patents

Anthracycline. Download PDF

Info

Publication number
CH648327A5
CH648327A5 CH5895/81A CH589581A CH648327A5 CH 648327 A5 CH648327 A5 CH 648327A5 CH 5895/81 A CH5895/81 A CH 5895/81A CH 589581 A CH589581 A CH 589581A CH 648327 A5 CH648327 A5 CH 648327A5
Authority
CH
Switzerland
Prior art keywords
formula
group
auramycin
sulfurmycin
compounds
Prior art date
Application number
CH5895/81A
Other languages
German (de)
English (en)
Inventor
Akiko Fujiwara
Tatsuo Hoshino
Masaaki Tazoe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH648327A5 publication Critical patent/CH648327A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
CH5895/81A 1980-10-16 1981-09-11 Anthracycline. CH648327A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8033399 1980-10-16

Publications (1)

Publication Number Publication Date
CH648327A5 true CH648327A5 (de) 1985-03-15

Family

ID=10516712

Family Applications (1)

Application Number Title Priority Date Filing Date
CH5895/81A CH648327A5 (de) 1980-10-16 1981-09-11 Anthracycline.

Country Status (6)

Country Link
US (1) US4401812A (en:Method)
JP (1) JPS5796000A (en:Method)
CH (1) CH648327A5 (en:Method)
DE (1) DE3141168A1 (en:Method)
FR (1) FR2492386A1 (en:Method)
IT (1) IT1144920B (en:Method)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3323025A1 (de) * 1983-06-25 1985-01-10 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3819092A1 (de) * 1988-06-04 1989-12-14 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
US4977084A (en) * 1989-02-16 1990-12-11 Board Of Trustees Operating Michigan State University Production, isolation, and identification of novel antifungal compounds
CN111544579A (zh) * 2020-03-13 2020-08-18 中国农业科学院北京畜牧兽医研究所 一种抗癌症的药物组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52136159A (en) * 1976-04-07 1977-11-14 Microbial Chem Res Found Anti/malignanttumor containing the same as active ingredients
US4039736A (en) * 1976-04-15 1977-08-02 Bristol-Myers Company Antibiotic compounds marcellomycin and musettamycin
JPS5323961A (en) * 1976-08-16 1978-03-06 Microbial Chem Res Found Antitumors
NL176004C (nl) * 1976-10-05 1985-02-01 Microbial Chem Res Found Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden.
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
JPS5811889B2 (ja) * 1978-02-15 1983-03-05 信越化学工業株式会社 塩化ビニル系重合体の製造方法
JPS5543012A (en) * 1978-09-20 1980-03-26 Sanraku Inc Novel anthracycline derivatine and its preparation
IT1196402B (it) * 1978-11-21 1988-11-16 Erba Farmitalia Antibiotici antitumorali
GB2048245B (en) * 1979-04-27 1983-03-16 Erba Farmitalia Biosynthetic antracyline glycoside
ZA802929B (en) * 1979-05-22 1981-05-27 Hoffmann La Roche Novel tetracyclic compounds and process for the preparation thereof
JPS5648893A (en) * 1979-09-07 1981-05-02 Sanraku Inc Preparation of anthracycline glycoside
PL124284B1 (en) * 1979-10-17 1983-01-31 Politechnika Gdanska Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group

Also Published As

Publication number Publication date
FR2492386A1 (fr) 1982-04-23
DE3141168A1 (de) 1982-06-03
IT1144920B (it) 1986-10-29
JPS5796000A (en) 1982-06-15
US4401812A (en) 1983-08-30
IT8124361A0 (it) 1981-10-06
FR2492386B1 (en:Method) 1984-12-14

Similar Documents

Publication Publication Date Title
DE2532568A1 (de) Aclacinomycine a und b und verfahren zu ihrer herstellung
DE2743654C3 (en:Method)
DE3887820T2 (de) Antibiotika, Benanomicine A und B und Dexylosylbenanomicin B, ihre Herstellung und Verwendung.
DE69020645T2 (de) Antitumor- und Antibiotikum-Substanz, ihre Herstellung und Verwendungen.
US4329339A (en) Anthracyclinones and derivatives thereof
DE2715255C3 (de) Anthracyclinglykoside MA 144-M, und MA 144-M2 und deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE69527445T2 (de) Aminooligosaccharid-derivate und verfahren zu ihrer herstellung
US4127714A (en) Anthracycline glycosides
US4536398A (en) Antiviral agents
DE69735099T2 (de) Antibiotika rk-1061 und verfahren zu ihrer herstellung
CH634079A5 (de) Verfahren zur herstellung eines neuen anthracyclinglycosids.
CH648327A5 (de) Anthracycline.
DE60128565T2 (de) Polycyclische xanthone als antibiotika
DE69816621T2 (de) Macrolide mit antitumoraktivität
EP0167954B1 (de) 1-Hydroxy-Cytorhodine, ein mikrobiologisches Verfahren zu ihrer Herstellung und ihre Verwendung als Cytostatika
DE3407979C2 (en:Method)
DE2738656C2 (en:Method)
DE3687189T2 (de) Antitumor- und antimikroben-verbindung, deren mikrobiologische herstellung und deren benutzung als arzneimittel.
DE4401546C2 (de) Streptomyces lavendofoliae DRKS Stamm, Verfahren zur Gewinnung der Aclacinomycine A, B, Y und von Aglycon durch Anwendung dieses Verfahrens
DE2818544A1 (de) Antibiotikum sf-1942, verfahren zu dessen herstellung und pharmazeutische zusammensetzung, die das antibiotikum sf-1942 enthaelt
DE2510868C3 (de) Nanaomycin A und Verfahren zur Herstellung der Antibiorica Nanaomycin A und Nanaomycin B
DE2638400A1 (de) Neue organische verbindung, ihre herstellung und verwendung
CH655109A5 (de) Physiologisch aktive substanzen ss 12538, verfahren zu deren herstellung und neuer, diese substanzen produzierender mikroorganismus.
DE1770204C (en:Method)
JPS5849235B2 (ja) 新抗生物質ｘｋ−９９およびその製造法

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased