CH645907A5 - Apramycin-derivate und deren pharmazeutisch annehmbaren saeureadditionssalze. - Google Patents

Apramycin-derivate und deren pharmazeutisch annehmbaren saeureadditionssalze. Download PDF

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Publication number
CH645907A5
CH645907A5 CH679581A CH679581A CH645907A5 CH 645907 A5 CH645907 A5 CH 645907A5 CH 679581 A CH679581 A CH 679581A CH 679581 A CH679581 A CH 679581A CH 645907 A5 CH645907 A5 CH 645907A5
Authority
CH
Switzerland
Prior art keywords
formula
apramycin
atoms
nhx
hydroxy
Prior art date
Application number
CH679581A
Other languages
German (de)
English (en)
Inventor
Kikuo Igarashi
Tsunetoshi Honma
Tamio Sugawara
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of CH645907A5 publication Critical patent/CH645907A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH679581A 1980-10-24 1981-10-23 Apramycin-derivate und deren pharmazeutisch annehmbaren saeureadditionssalze. CH645907A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55149820A JPS5772998A (en) 1980-10-24 1980-10-24 Novel appamycin derivative

Publications (1)

Publication Number Publication Date
CH645907A5 true CH645907A5 (de) 1984-10-31

Family

ID=15483409

Family Applications (1)

Application Number Title Priority Date Filing Date
CH679581A CH645907A5 (de) 1980-10-24 1981-10-23 Apramycin-derivate und deren pharmazeutisch annehmbaren saeureadditionssalze.

Country Status (7)

Country Link
US (1) US4370475A (en, 2012)
JP (1) JPS5772998A (en, 2012)
BE (1) BE890853A (en, 2012)
CH (1) CH645907A5 (en, 2012)
DE (1) DE3142111A1 (en, 2012)
FR (1) FR2498606A1 (en, 2012)
GB (1) GB2086388B (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56138180A (en) * 1980-03-28 1981-10-28 Microbial Chem Res Found Di-n6',o3-demethylistamycin a and its preparation
US4468513A (en) * 1980-09-22 1984-08-28 Eli Lilly And Company 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides
US4458065A (en) * 1983-02-17 1984-07-03 Eli Lilly And Company 7-N-(Substituted-apramycin antibiotic derivatives and intermediates therefor
EP2616079B1 (en) * 2010-09-13 2015-10-14 University of Zürich Treatment of bacterial infectious diseases
MY186959A (en) * 2015-07-30 2021-08-26 Microbial Chem Res Found New effective aminoglycoside antibiotic for multidrug-resistant bacteria
JP2021138615A (ja) * 2018-05-31 2021-09-16 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 多剤耐性菌に有効なアミノグリコシド抗生物質の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532453A (en) * 1976-05-28 1978-01-11 Suami T Neamin derivatives and process for manufacture thereof

Also Published As

Publication number Publication date
GB2086388B (en) 1984-04-18
FR2498606B1 (en, 2012) 1984-11-02
DE3142111A1 (de) 1982-06-09
JPS5772998A (en) 1982-05-07
FR2498606A1 (fr) 1982-07-30
US4370475A (en) 1983-01-25
BE890853A (fr) 1982-02-15
GB2086388A (en) 1982-05-12

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PL Patent ceased
PL Patent ceased