CH645898A5 - Gegebenenfalls 8-substituierte 7-phenyl-1,2,4-triazolo (1,5-c)-pyrimidin-5-amine und -amide. - Google Patents

Gegebenenfalls 8-substituierte 7-phenyl-1,2,4-triazolo (1,5-c)-pyrimidin-5-amine und -amide. Download PDF

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Publication number
CH645898A5
CH645898A5 CH603080A CH603080A CH645898A5 CH 645898 A5 CH645898 A5 CH 645898A5 CH 603080 A CH603080 A CH 603080A CH 603080 A CH603080 A CH 603080A CH 645898 A5 CH645898 A5 CH 645898A5
Authority
CH
Switzerland
Prior art keywords
radical
carbon atoms
phenyl
formula
triazolo
Prior art date
Application number
CH603080A
Other languages
German (de)
English (en)
Inventor
Hans A Wagner
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of CH645898A5 publication Critical patent/CH645898A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH603080A 1979-08-08 1980-08-08 Gegebenenfalls 8-substituierte 7-phenyl-1,2,4-triazolo (1,5-c)-pyrimidin-5-amine und -amide. CH645898A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6470779A 1979-08-08 1979-08-08

Publications (1)

Publication Number Publication Date
CH645898A5 true CH645898A5 (de) 1984-10-31

Family

ID=22057763

Family Applications (1)

Application Number Title Priority Date Filing Date
CH603080A CH645898A5 (de) 1979-08-08 1980-08-08 Gegebenenfalls 8-substituierte 7-phenyl-1,2,4-triazolo (1,5-c)-pyrimidin-5-amine und -amide.

Country Status (7)

Country Link
JP (1) JPS5632479A (sr)
AU (1) AU531507B2 (sr)
CA (2) CA1246063A (sr)
CH (1) CH645898A5 (sr)
DE (1) DE3029871C2 (sr)
FR (1) FR2463143A1 (sr)
GB (1) GB2056449A (sr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3029871C2 (de) 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135184A (da) * 1983-03-03 1984-10-10 Riker Laboratories Inc Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner
US4528288A (en) * 1983-05-02 1985-07-09 Riker Laboratories, Inc. Substituted triazolo[1,5-c]pyrimidines
US4532242A (en) * 1983-05-02 1985-07-30 Riker Laboratories, Inc. Substituted triazolo[4,3-c]pyrimidines
US4483987A (en) * 1983-06-20 1984-11-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides
US4866063A (en) * 1988-12-22 1989-09-12 G. D. Searle & Co. Diol metabolites of 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
US5952331A (en) * 1996-05-23 1999-09-14 Syntex (Usa) Inc. Aryl pyrimidine derivatives
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
AU2011328237A1 (en) 2010-11-09 2013-05-23 Cellzome Limited Pyridine compounds and aza analogues thereof as TYK2 inhibitors
US20220194950A1 (en) * 2019-04-03 2022-06-23 Tera Stone Co., Ltd Triazolopyrimidines based on thymine nucleobase and methods for producing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1205144A (fr) * 1957-06-14 1960-01-29 Farmaceutici Italia Procédé pour la synthèse de 7-méthyl-s. triazol (4, 3-c) pyrimidines substituéesen position 5
US3284542A (en) 1963-03-22 1966-11-08 Rexall Drug Chemical Preparation of high impact compositions from vinyl aromatic monomers and rubbery diolefin polymers
US3244715A (en) 1964-10-30 1966-04-05 Smith Kline French Lab Phenylimidazo [4, 5-d] pyridazines
US3461123A (en) 1968-04-12 1969-08-12 Merck & Co Inc 1h-imidazo(4,5-b)pyrazin-2-ones and processes for their preparation
GB2056449A (en) 1979-08-08 1981-03-18 Searle & Co 8-substituted-7-phenyl-1,2,4- triazolo[4,3-c] pyrimidine-5-amines and amides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3029871C2 (de) 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält

Also Published As

Publication number Publication date
AU531507B2 (en) 1983-08-25
JPH029592B2 (sr) 1990-03-02
CA1246064B (en) 1988-12-06
FR2463143B1 (sr) 1983-12-16
DE3029871A1 (de) 1981-02-26
CA1246063B (en) 1988-12-06
GB2056449A (en) 1981-03-18
AU6115380A (en) 1981-02-12
DE3029871C2 (de) 1987-01-15
CA1246063A (en) 1988-12-06
CA1246064A (en) 1988-12-06
JPS5632479A (en) 1981-04-01
FR2463143A1 (fr) 1981-02-20

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