CH644368A5 - Hydroxylated pyrimidine derivatives, their preparation and therapeutic composition containing them - Google Patents

Hydroxylated pyrimidine derivatives, their preparation and therapeutic composition containing them Download PDF

Info

Publication number
CH644368A5
CH644368A5 CH165080A CH165080A CH644368A5 CH 644368 A5 CH644368 A5 CH 644368A5 CH 165080 A CH165080 A CH 165080A CH 165080 A CH165080 A CH 165080A CH 644368 A5 CH644368 A5 CH 644368A5
Authority
CH
Switzerland
Prior art keywords
pyrimidine
hydroxylated
therapeutic composition
preparation
composition containing
Prior art date
Application number
CH165080A
Other languages
English (en)
French (fr)
Inventor
Andre Esanu
Original Assignee
Soc D Etudes Prod Chimique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26270867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH644368(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Soc D Etudes Prod Chimique filed Critical Soc D Etudes Prod Chimique
Publication of CH644368A5 publication Critical patent/CH644368A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH165080A 1979-03-10 1980-03-03 Hydroxylated pyrimidine derivatives, their preparation and therapeutic composition containing them CH644368A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7908494 1979-03-10
GB7914987 1979-04-30

Publications (1)

Publication Number Publication Date
CH644368A5 true CH644368A5 (en) 1984-07-31

Family

ID=26270867

Family Applications (1)

Application Number Title Priority Date Filing Date
CH165080A CH644368A5 (en) 1979-03-10 1980-03-03 Hydroxylated pyrimidine derivatives, their preparation and therapeutic composition containing them

Country Status (24)

Country Link
JP (1) JPS55122768A (lt)
AR (1) AR222691A1 (lt)
AU (1) AU533547B2 (lt)
BE (1) BE881752A (lt)
CA (1) CA1132561A (lt)
CH (1) CH644368A5 (lt)
DE (3) DE3009071C2 (lt)
EG (1) EG14282A (lt)
FI (1) FI66357C (lt)
FR (2) FR2451191A1 (lt)
GB (1) GB2045756B (lt)
HK (1) HK55383A (lt)
IE (1) IE49547B1 (lt)
IN (1) IN153791B (lt)
LU (1) LU82185A1 (lt)
MX (1) MX6218E (lt)
MY (1) MY8400200A (lt)
NL (1) NL184833C (lt)
NO (1) NO154054C (lt)
NZ (1) NZ192927A (lt)
OA (1) OA06484A (lt)
PT (1) PT70882A (lt)
SE (1) SE435180B (lt)
SG (1) SG22683G (lt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE894517A (fr) * 1981-10-16 1983-01-17 Sod Conseils Rech Applic Nouveau derive de l'isopropylamino pyrimidine, sa preparation et composition therapeutiques a base de ses composes
US4673677A (en) * 1983-10-03 1987-06-16 Pfizer Inc. Method for treatment of gastrointestinal disorders
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4711888A (en) 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines
WO1989000423A1 (en) * 1987-07-09 1989-01-26 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US4910204A (en) * 1988-06-28 1990-03-20 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
US4940712A (en) * 1989-05-26 1990-07-10 Pfizer Inc. Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US9133212B1 (en) * 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB741667A (en) * 1952-12-05 1955-12-07 Ici Ltd New pyrimidine derivatives
GB756189A (en) * 1954-02-01 1956-08-29 Ici Ltd New pyrimidine derivatives
ZA711152B (en) * 1970-03-02 1971-11-24 Ici Ltd Manufacture of pyrimidines
GB1525995A (en) * 1976-02-18 1978-09-27 Soc D Etudes Prod Chimique Aminopyrimidine salt

Also Published As

Publication number Publication date
IE49547B1 (en) 1985-10-30
FI66357C (fi) 1984-10-10
HK55383A (en) 1983-11-25
FI800566A (fi) 1980-09-11
GB2045756B (en) 1983-01-26
DE3009071A1 (de) 1980-09-11
EG14282A (en) 1983-09-30
NZ192927A (en) 1981-07-13
JPS55122768A (en) 1980-09-20
SE435180B (sv) 1984-09-10
DE3050999C2 (de) 1986-08-14
PT70882A (en) 1980-03-01
LU82185A1 (fr) 1980-06-06
DE3016752A1 (de) 1980-12-04
NL184468B (nl) 1989-03-01
IN153791B (lt) 1984-08-18
FR2451191A1 (fr) 1980-10-10
NO154054C (no) 1986-07-09
OA06484A (fr) 1981-07-31
SE8001812L (sv) 1980-09-11
NL184833C (nl) 1989-11-16
DE3050999A1 (lt) 1985-08-14
FR2451191B1 (lt) 1983-04-29
DE3009071C2 (de) 1985-11-14
SG22683G (en) 1983-12-16
NO800664L (no) 1980-09-11
FI66357B (fi) 1984-06-29
GB2045756A (en) 1980-11-05
FR2451370B1 (lt) 1983-05-13
MX6218E (es) 1984-12-21
FR2451370A1 (fr) 1980-10-10
NL184833B (nl) 1989-06-16
AU533547B2 (en) 1983-12-01
JPS6126996B2 (lt) 1986-06-23
AR222691A1 (es) 1981-06-15
AU5624880A (en) 1980-09-18
CA1132561A (en) 1982-09-28
DE3016752C2 (lt) 1987-06-25
IE800477L (en) 1980-09-10
NO154054B (no) 1986-04-01
NL8001289A (nl) 1980-09-12
MY8400200A (en) 1984-12-31
BE881752A (fr) 1980-05-30

Similar Documents

Publication Publication Date Title
CH644368A5 (en) Hydroxylated pyrimidine derivatives, their preparation and therapeutic composition containing them
FR2663633A1 (fr) Nouvelles chalcones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE3346573A1 (de) 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
FR2555049A1 (fr) Medicaments a base de carboxymethoxy-7 furo-(3,4-c)-pyridine
UA73507C2 (en) Indole derivatives, compositions (variants) and their use
CA1145752A (fr) Procede de preparation de nouveaux derives du n'tetrahydropyridinyl-indoles et de leurs sels
FR2483929A1 (fr) Nouvelles adenosines n6-substituees utiles comme medicaments antihypertenseurs, compositions therapeutiques et formes pharmaceutiques les contenant, et leur procede de preparation
LU82332A1 (fr) Preparation des derives hydroxyles de l'isopropylamino-pyrimidine
LU83928A1 (fr) Acides amino-2 halogenobenzoyl-3 methyphenylacetiques et leurs esters et sels utiles comme medicaments anti-inflammatoires et analgesiques
CH645103A5 (fr) Derives halogenes de l'isopropylamino pyrimidine, leur preparation et composition therapeutique les contenant.
FR2608157A1 (fr) Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires
EP0256909B1 (fr) Acide N,N-bis-(4-fluorophényl) carbamoylacétohydroxamique et composition pharmaceutique le contenant
FR2547822A1 (fr) Acylpiperazinoquinazolines substituees utiles comme medicaments et procede pour leur preparation
HU201082B (en) Enolethers of 6-chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno(2,3-e)-1,2-thiazin-3-carboxylic acid amide-1,1-dioxide, a process for their preparation and their use.
EP0043752A1 (fr) Dérivé de pyranno-indole et son procédé de préparation
EP0003920B1 (fr) Thiéno (3,2-c) et thiéno (2,3-c)pyridines, leur procédé de préparation et leur application en thérapeutique
FR2465733A1 (fr) Nouveaux derives imidazolylethoxymethyliques de 1,3-dioxoloquinoleines utiles notamment comme medicaments antibacteriens et antifongiques, leur procede de preparation et compositions therapeutiques et formes pharmaceutiques les contenant
FR2520618A1 (fr) Application therapeutique de certains derives de la (trimethoxy-3,4,5) cinnamoyl-1 piperazine et de leurs sels d'acide
EP0347305B1 (fr) [(Aryl-4-pipérazinyl-1)-2 éthoxy]-3 p-cymène, les dérivés ortho, méta, para monosubstitués ou disubstitués sur le noyau phényle dudit produit, le procédé de préparation desdits dérivés, et les médicaments contenant lesdits composés comme principe actif
EP0135406A1 (fr) Pyrrolidinones actives sur le système nerveux central, leur procédé de préparation, les médicaments en contenant
FR2518537A1 (fr) Nouveaux derives de l'acide phenylacetique, leur preparation et compositions les contenant
EP0298818B1 (fr) Dérivés de la 1-benzène-sulfonyl 2-oxo 5-alkylthio pyrrolidine, leur procédé et intermédiaires de préparation, leur application comme médicaments et les compositions les renfermant
EP0003286A2 (de) Ergopeptidalkaloid-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
CH632763A5 (en) Triazolothiadiazine derivatives and processes for preparing them
EP0061406A1 (fr) Dérivés d'acide benzamido-alkyl-hydroxamique, procédé de préparation et composition thérapeutique

Legal Events

Date Code Title Description
PL Patent ceased