CH643243A5 - Cis- et trans-3-aryloxy-4-hydroxypyrrolidines et leurs derives, utiles notamment en medecine veterinaire comme antidepresseurs. - Google Patents

Cis- et trans-3-aryloxy-4-hydroxypyrrolidines et leurs derives, utiles notamment en medecine veterinaire comme antidepresseurs. Download PDF

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Publication number
CH643243A5
CH643243A5 CH10280A CH10280A CH643243A5 CH 643243 A5 CH643243 A5 CH 643243A5 CH 10280 A CH10280 A CH 10280A CH 10280 A CH10280 A CH 10280A CH 643243 A5 CH643243 A5 CH 643243A5
Authority
CH
Switzerland
Prior art keywords
trans
benzyl
pyrrolidinol
mixture
cis
Prior art date
Application number
CH10280A
Other languages
English (en)
French (fr)
Inventor
David Allan Walsh
William John Jun Welstead
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of CH643243A5 publication Critical patent/CH643243A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CH10280A 1979-01-09 1980-01-08 Cis- et trans-3-aryloxy-4-hydroxypyrrolidines et leurs derives, utiles notamment en medecine veterinaire comme antidepresseurs. CH643243A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US215179A 1979-01-09 1979-01-09

Publications (1)

Publication Number Publication Date
CH643243A5 true CH643243A5 (fr) 1984-05-30

Family

ID=21699450

Family Applications (1)

Application Number Title Priority Date Filing Date
CH10280A CH643243A5 (fr) 1979-01-09 1980-01-08 Cis- et trans-3-aryloxy-4-hydroxypyrrolidines et leurs derives, utiles notamment en medecine veterinaire comme antidepresseurs.

Country Status (9)

Country Link
JP (1) JPS5598160A (it)
CA (1) CA1133495A (it)
CH (1) CH643243A5 (it)
DE (1) DE3000625A1 (it)
FR (1) FR2446279B1 (it)
GB (1) GB2040933B (it)
IT (1) IT1127967B (it)
MX (1) MX6634E (it)
SE (1) SE435927B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45511B1 (en) 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
US4547514A (en) * 1983-12-05 1985-10-15 A. H. Robins Company, Incorporated Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity
JPS60178860A (ja) * 1984-02-24 1985-09-12 Sankyo Co Ltd ３−メルカプトピロリジンまたはその塩の製法
JPS6157552A (ja) * 1984-08-29 1986-03-24 Toyama Chem Co Ltd ３−アミノピロリジンまたはその塩の製法
DE3813416A1 (de) * 1988-04-21 1989-11-02 Hoechst Ag 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte
EP0407701A3 (en) * 1989-05-15 1992-04-22 Fujisawa Pharmaceutical Co., Ltd. Antiretroviral pyrroline and pyrrolidine sulfonic acid derivatives
JP5323063B2 (ja) 2007-05-31 2013-10-23 塩野義製薬株式会社 オキシイミノ化合物およびその使用
ES2408159T3 (es) * 2008-06-11 2013-06-18 Shionogi & Co., Ltd. Compuestos de oxicarbamoilo y su utilización

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1000308A (fr) * 1949-05-28 1952-02-11 Basf Ag Procédé pour la production de 3. 4-dioxypyrrolidines
FR1000310A (fr) * 1949-06-18 1952-02-11 Basf Ag Procédé pour la production de dérivés de pyrrolidine
FR1532221A (fr) * 1963-10-22 1968-07-12 Robins Co Inc A H Procédé de production de n, n-di (aryl monocarbocyclique)-carbamates de 1-(alkylinférieur)-3-pyrrolidyle
CH521338A (de) * 1967-03-13 1972-04-15 Robins Co Inc A H Verfahren zur Herstellung von neuen Pyrrolidinderivaten
US3577415A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-substituted phenoxypyrrolidines
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof

Also Published As

Publication number Publication date
IT1127967B (it) 1986-05-28
SE435927B (sv) 1984-10-29
SE8000085L (sv) 1980-08-26
GB2040933B (en) 1983-07-20
DE3000625C2 (it) 1989-04-20
FR2446279A1 (fr) 1980-08-08
CA1133495A (en) 1982-10-12
JPS5598160A (en) 1980-07-25
IT8067020A0 (it) 1980-01-08
DE3000625A1 (de) 1980-07-17
MX6634E (es) 1985-09-12
FR2446279B1 (fr) 1985-10-31
GB2040933A (en) 1980-09-03
JPS648621B2 (it) 1989-02-14

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