CH639659A5 - Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. - Google Patents
Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. Download PDFInfo
- Publication number
- CH639659A5 CH639659A5 CH1283578A CH1283578A CH639659A5 CH 639659 A5 CH639659 A5 CH 639659A5 CH 1283578 A CH1283578 A CH 1283578A CH 1283578 A CH1283578 A CH 1283578A CH 639659 A5 CH639659 A5 CH 639659A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- formula
- ch2ch
- new
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1283578A CH639659A5 (de) | 1978-12-18 | 1978-12-18 | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
DE19792949491 DE2949491A1 (de) | 1978-12-18 | 1979-12-08 | 1,4-dihydropyridine, ihre herstellung und verwendung |
SE7910188A SE445219B (sv) | 1978-12-18 | 1979-12-11 | 1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition |
BE1/9643A BE880591A (fr) | 1978-12-18 | 1979-12-13 | Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments |
IT51095/79A IT1164097B (it) | 1978-12-18 | 1979-12-14 | "1,4-di idropiridine loro preparazione e loro applicazione come medicamenti" |
NL7909024A NL193066C (nl) | 1978-12-18 | 1979-12-14 | Methyl,isopropyl-4-(2,1,3-benzoxadiazool-4-yl)-2,6-dimethyl-1,4-dihydro pyridine-3,5-dicarboxylaat en farmaceutisch preparaat dat deze verbinding bevat. |
GB08215988A GB2103203B (en) | 1978-12-18 | 1979-12-14 | 1,4-dihydropyridines, their preparation and pharmaceutical compositions containing them |
GB7943113A GB2037766B (en) | 1978-12-18 | 1979-12-14 | 1,4-dihydropyridines their preparation and pharmaceutical compositions containing them |
CY1321A CY1321A (en) | 1978-12-18 | 1979-12-14 | 1,4-dihydropyridines their preparation and pharmaceutical compositions containing them |
JP16396579A JPS5583783A (en) | 1978-12-18 | 1979-12-17 | 1*44dihydropyridine derivative |
NZ192422A NZ192422A (en) | 1978-12-18 | 1979-12-17 | Benzoxadiazoles and benzothiadiazoles with 1,4-dihydropyridine moiety pharmaceutical compositions |
IE2445/79A IE49496B1 (en) | 1978-12-18 | 1979-12-17 | A 1,4-dihydropyridine derivative,its preparation and pharmaceutical compositions containing it |
AU53896/79A AU536055B2 (en) | 1978-12-18 | 1979-12-17 | Derivatives of 1,4 dihydropyridine substituted by benzoxadiazole or benzthiadiazole |
FR7930829A FR2444681A1 (fr) | 1978-12-18 | 1979-12-17 | Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments |
IE1165/83A IE49497B1 (en) | 1978-12-18 | 1979-12-17 | 1,4-dihydropyridines,their preparation and pharmaceutical compositions containing them |
ZA00796842A ZA796842B (en) | 1978-12-18 | 1979-12-18 | 1,4-dihydropyridines, their preparation and pharmaceutical compositions containing them |
PH24383A PH19536A (en) | 1977-06-20 | 1980-08-01 | Benzoxadiazoles and benzothiadiazoles and pharmaceutical composition containing them |
NZ199437A NZ199437A (en) | 1978-12-18 | 1982-01-07 | 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydro-3-methoxycarbonylpyridine-5-carboxylic acid isopropyl ester and pharmaceutical compositions |
US06/359,751 US4466972A (en) | 1977-06-20 | 1982-03-19 | Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them |
SG975/85A SG97585G (en) | 1978-12-18 | 1985-12-20 | A 1,4-dihydropyridine derivative,its preparation and pharmaceutical compositions containing it |
MY130/85A MY8500130A (en) | 1978-12-18 | 1985-12-30 | A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it |
KE3593A KE3593A (en) | 1978-12-18 | 1986-01-08 | A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it |
HK160/86A HK16086A (en) | 1978-12-18 | 1986-03-06 | A 1,4-dihydropyridine derivate its preparation and pharmaceutical compositions containing it |
NL990014C NL990014I1 (nl) | 1978-12-18 | 1999-05-11 | Methyl, isopropyl-4-(2,1,3-benzoxadiazool-4-yl)-2,6-dimethyl-1,4-dihydro pyridine-3,5-dicarboxylaat en farmaceutisch preparaat dat deze verbinding bevat. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1283578A CH639659A5 (de) | 1978-12-18 | 1978-12-18 | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
Publications (1)
Publication Number | Publication Date |
---|---|
CH639659A5 true CH639659A5 (de) | 1983-11-30 |
Family
ID=4386824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1283578A CH639659A5 (de) | 1977-06-20 | 1978-12-18 | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS5583783A (es) |
AU (1) | AU536055B2 (es) |
BE (1) | BE880591A (es) |
CH (1) | CH639659A5 (es) |
CY (1) | CY1321A (es) |
DE (1) | DE2949491A1 (es) |
FR (1) | FR2444681A1 (es) |
GB (2) | GB2037766B (es) |
HK (1) | HK16086A (es) |
IE (1) | IE49496B1 (es) |
IT (1) | IT1164097B (es) |
KE (1) | KE3593A (es) |
MY (1) | MY8500130A (es) |
NL (2) | NL193066C (es) |
NZ (1) | NZ192422A (es) |
SE (1) | SE445219B (es) |
SG (1) | SG97585G (es) |
ZA (1) | ZA796842B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3022030A1 (de) * | 1980-06-12 | 1981-12-17 | Bayer Ag, 5090 Leverkusen | 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel |
CH655658B (es) * | 1980-09-18 | 1986-05-15 | ||
EP0080220B1 (en) * | 1981-11-17 | 1986-02-19 | FISONS plc | Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals |
ZA83959B (en) * | 1982-03-10 | 1984-09-26 | Sandoz Ltd | 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them |
US4414213A (en) * | 1982-03-22 | 1983-11-08 | Mead Johnson & Company | Dihydropyridyl cyclic imidate esters and their pharmaceutical use |
FR2528431B1 (fr) * | 1982-06-15 | 1986-01-10 | Sandoz Sa | Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments |
IL68975A (en) * | 1982-06-15 | 1987-01-30 | Sandoz Ag | 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them |
JPS5978186A (ja) * | 1982-10-27 | 1984-05-04 | Yoshitomi Pharmaceut Ind Ltd | 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体 |
US4794111A (en) * | 1984-05-23 | 1988-12-27 | Bayer Aktiengesellschaft | Dihydropyridine preparations containing β-blockers |
NL194389C (nl) * | 1984-06-14 | 2002-03-04 | Novartis Ag | Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager. |
US5260321A (en) * | 1984-11-12 | 1993-11-09 | Sandoz Ltd. | Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins |
NL194822C (nl) * | 1985-10-01 | 2003-04-03 | Novartis Ag | Preparaat voor orale toediening met geregelde afgifte en werkwijze voor de bereiding ervan. |
DE3542794A1 (de) * | 1985-12-04 | 1987-06-11 | Bayer Ag | Antihypertensives kombinationspraeparat |
GB8626217D0 (en) * | 1986-11-03 | 1986-12-03 | Sandoz Ltd | Pharmaceutical compositions |
US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
KR940003492B1 (ko) * | 1988-10-27 | 1994-04-23 | 주식회사 유한양행 | 1,4-디하이드로피리딘유도체 및 그의 제조방법 |
DE4222770A1 (de) * | 1992-07-10 | 1994-01-13 | Bayer Ag | Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine |
IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
WO2005023787A1 (en) * | 2003-09-10 | 2005-03-17 | Shasun Chemicals And Drugs Limited | Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde |
CN103613584B (zh) * | 2013-11-27 | 2016-04-27 | 沈阳药科大学 | 一种伊拉地平合成产物后处理的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
FR2320750A1 (fr) * | 1975-08-12 | 1977-03-11 | Hexachimie | Dihydro-1,4 pyridines et leur application therapeutique |
DE2616991A1 (de) * | 1976-04-17 | 1977-10-27 | Bayer Ag | Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
JPS5373327A (en) * | 1976-12-13 | 1978-06-29 | Matsushita Electric Ind Co Ltd | Power source system |
DK149855C (da) * | 1977-06-20 | 1987-04-21 | Sandoz Ag | Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater |
-
1978
- 1978-12-18 CH CH1283578A patent/CH639659A5/de not_active IP Right Cessation
-
1979
- 1979-12-08 DE DE19792949491 patent/DE2949491A1/de active Granted
- 1979-12-11 SE SE7910188A patent/SE445219B/sv not_active IP Right Cessation
- 1979-12-13 BE BE1/9643A patent/BE880591A/fr not_active IP Right Cessation
- 1979-12-14 CY CY1321A patent/CY1321A/xx unknown
- 1979-12-14 GB GB7943113A patent/GB2037766B/en not_active Expired
- 1979-12-14 NL NL7909024A patent/NL193066C/nl not_active IP Right Cessation
- 1979-12-14 GB GB08215988A patent/GB2103203B/en not_active Expired
- 1979-12-14 IT IT51095/79A patent/IT1164097B/it active Protection Beyond IP Right Term
- 1979-12-17 NZ NZ192422A patent/NZ192422A/xx unknown
- 1979-12-17 AU AU53896/79A patent/AU536055B2/en not_active Expired
- 1979-12-17 FR FR7930829A patent/FR2444681A1/fr active Granted
- 1979-12-17 IE IE2445/79A patent/IE49496B1/en not_active IP Right Cessation
- 1979-12-17 JP JP16396579A patent/JPS5583783A/ja active Granted
- 1979-12-18 ZA ZA00796842A patent/ZA796842B/xx unknown
-
1985
- 1985-12-20 SG SG975/85A patent/SG97585G/en unknown
- 1985-12-30 MY MY130/85A patent/MY8500130A/xx unknown
-
1986
- 1986-01-08 KE KE3593A patent/KE3593A/xx unknown
- 1986-03-06 HK HK160/86A patent/HK16086A/xx not_active IP Right Cessation
-
1999
- 1999-05-11 NL NL990014C patent/NL990014I1/nl unknown
Also Published As
Publication number | Publication date |
---|---|
GB2103203A (en) | 1983-02-16 |
SG97585G (en) | 1986-07-18 |
KE3593A (en) | 1986-02-07 |
JPS5583783A (en) | 1980-06-24 |
AU5389679A (en) | 1980-06-26 |
HK16086A (en) | 1986-03-14 |
GB2103203B (en) | 1983-06-08 |
SE7910188L (sv) | 1980-06-19 |
IT7951095A0 (it) | 1979-12-14 |
DE2949491C2 (es) | 1988-10-27 |
FR2444681A1 (fr) | 1980-07-18 |
CY1321A (en) | 1986-06-27 |
NZ192422A (en) | 1982-09-14 |
IT1164097B (it) | 1987-04-08 |
SE445219B (sv) | 1986-06-09 |
NL7909024A (nl) | 1980-06-20 |
MY8500130A (en) | 1985-12-31 |
BE880591A (fr) | 1980-06-13 |
IE792445L (en) | 1980-06-18 |
ZA796842B (en) | 1981-07-29 |
GB2037766B (en) | 1983-02-16 |
DE2949491A1 (de) | 1980-06-26 |
FR2444681B1 (es) | 1982-10-29 |
JPH0369910B2 (es) | 1991-11-05 |
NL193066B (nl) | 1998-05-06 |
NL193066C (nl) | 1998-09-08 |
NL990014I1 (nl) | 1999-07-01 |
GB2037766A (en) | 1980-07-16 |
AU536055B2 (en) | 1984-04-19 |
IE49496B1 (en) | 1985-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PFA | Name/firm changed |
Owner name: SANDOZ AG TRANSFER- NOVARTIS AG |
|
PL | Patent ceased |