CH639075A5 - Ethers dibenzyliques substitues actifs sur le plan therapeutique. - Google Patents

Ethers dibenzyliques substitues actifs sur le plan therapeutique. Download PDF

Info

Publication number
CH639075A5
CH639075A5 CH456979A CH456979A CH639075A5 CH 639075 A5 CH639075 A5 CH 639075A5 CH 456979 A CH456979 A CH 456979A CH 456979 A CH456979 A CH 456979A CH 639075 A5 CH639075 A5 CH 639075A5
Authority
CH
Switzerland
Prior art keywords
acid addition
solvent
imidazolylmethyl
pharmaceutical
carried out
Prior art date
Application number
CH456979A
Other languages
English (en)
French (fr)
Inventor
Dante Nardi
Elena Massarani
Alberto Tajana
Mario Veronese
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of CH639075A5 publication Critical patent/CH639075A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
CH456979A 1978-05-18 1979-05-16 Ethers dibenzyliques substitues actifs sur le plan therapeutique. CH639075A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23546/78A IT1096361B (it) 1978-05-18 1978-05-18 Dibenzileteri sostituiti terapeuticamente attivi

Publications (1)

Publication Number Publication Date
CH639075A5 true CH639075A5 (fr) 1983-10-31

Family

ID=11208025

Family Applications (1)

Application Number Title Priority Date Filing Date
CH456979A CH639075A5 (fr) 1978-05-18 1979-05-16 Ethers dibenzyliques substitues actifs sur le plan therapeutique.

Country Status (29)

Country Link
JP (1) JPS605592B2 (fi)
AR (1) AR219596A1 (fi)
AT (1) AT372950B (fi)
AU (1) AU523053B2 (fi)
CA (1) CA1115718A (fi)
CH (1) CH639075A5 (fi)
DD (1) DD143608A5 (fi)
DE (1) DE2917244C2 (fi)
DK (1) DK153838C (fi)
EG (1) EG14345A (fi)
ES (1) ES480552A1 (fi)
FI (1) FI71309C (fi)
FR (1) FR2426047A1 (fi)
GB (1) GB2025395B (fi)
GR (1) GR68396B (fi)
HU (1) HU182565B (fi)
IE (1) IE48372B1 (fi)
IL (1) IL57245A (fi)
IT (1) IT1096361B (fi)
MX (1) MX5927E (fi)
NL (2) NL189255C (fi)
NO (1) NO152840C (fi)
NZ (1) NZ190412A (fi)
PH (1) PH14782A (fi)
PT (1) PT69537A (fi)
SE (1) SE444812B (fi)
SU (1) SU816399A3 (fi)
YU (1) YU112279A (fi)
ZA (1) ZA792015B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1155853A (en) * 1980-06-06 1983-10-25 Joseph A. Martin Imidazole derivatives and preparation thereof
EP0117811A3 (fr) * 1983-02-23 1987-06-03 Sanofi S.A. Compositions pharmaceutiques antifongiques utilisables par voie orale
FR2541114B1 (fr) * 1983-02-23 1986-04-11 Sanofi Sa Compositions pharmaceutiques antifongiques utilisables par voie orale contenant de l'omoconazole
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
DE3413365A1 (de) * 1984-04-09 1985-12-19 Merz + Co GmbH & Co, 6000 Frankfurt Substituierte phenylethylderivate, verfahren zu ihrer herstellung und pharmazeutische mittel
IT1200422B (it) * 1985-03-19 1989-01-18 Ripari Gero Ist Farm Biolog Composto con attivita' antimicrobia,sua preparazione e composizioni farmaceutiche che lo contengono
ES2249992B1 (es) 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Un procedimiento para fabricar compuestos enantiomericos del imidazol.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
GB1475271A (en) * 1975-04-30 1977-06-01 Pfizer Ltd 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents

Also Published As

Publication number Publication date
GB2025395A (en) 1980-01-23
CA1115718A (en) 1982-01-05
JPS605592B2 (ja) 1985-02-12
IT7823546A0 (it) 1978-05-18
FR2426047B1 (fi) 1982-11-05
DE2917244C2 (de) 1985-09-05
SE7904319L (sv) 1979-11-19
NL930014I1 (nl) 1993-05-03
DE2917244A1 (de) 1979-11-22
NL930014I2 (nl) 1993-09-16
IT1096361B (it) 1985-08-26
GR68396B (fi) 1981-12-29
NL189255C (nl) 1993-02-16
IE48372B1 (en) 1984-12-26
IL57245A (en) 1983-02-23
NO791599L (no) 1979-11-20
SU816399A3 (ru) 1981-03-23
FI71309C (fi) 1986-12-19
PH14782A (en) 1981-12-09
DK196579A (da) 1979-11-19
GB2025395B (en) 1982-07-28
JPS54151974A (en) 1979-11-29
DK153838B (da) 1988-09-12
ZA792015B (en) 1980-04-30
SE444812B (sv) 1986-05-12
DK153838C (da) 1989-01-30
HU182565B (en) 1984-02-28
EG14345A (en) 1983-09-30
YU112279A (en) 1983-01-21
FR2426047A1 (fr) 1979-12-14
MX5927E (es) 1984-08-29
NO152840C (no) 1985-11-27
NL7903872A (nl) 1979-11-20
IE790958L (en) 1979-11-18
DD143608A5 (de) 1980-09-03
FI791543A (fi) 1979-11-19
ES480552A1 (es) 1980-04-01
IL57245A0 (en) 1979-09-30
AU4714979A (en) 1979-11-22
NZ190412A (en) 1981-03-16
FI71309B (fi) 1986-09-09
AT372950B (de) 1983-11-25
AU523053B2 (en) 1982-07-08
PT69537A (fr) 1979-05-01
NO152840B (no) 1985-08-19
ATA345079A (de) 1983-04-15
AR219596A1 (es) 1980-08-29

Similar Documents

Publication Publication Date Title
FR2458545A1 (fr) Procede de preparation de derives de benzylimidazole, nouveaux produits ainsi obtenus, et leur utilisation pour leurs activites antimycotique et fongicide
BE851310A (fr) Nouveaux derives de la tetrahydro-equinocandine b
EP2142501B1 (fr) Procede de preparation de derives de porphyrine, telle que la protoporphyrine (ix) et intermediaire de synthese
EP0021940B1 (fr) Nouveaux dérivés aminés du benzothiazole, leur procédé de préparation et leur application en thérapeutique
CH639075A5 (fr) Ethers dibenzyliques substitues actifs sur le plan therapeutique.
EP0319412A1 (fr) Nouveaux dérivés flavonoides pipérazinyl-2 oxo-2 éthylène substitués, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
EP0410834A1 (fr) Médicaments à base de dérivés de benzoxadiazine-4, 1, 2 nouveaux dérivés et leurs procédés de préparation
EP0479631A1 (fr) Dérivés du spiro [4.5]décane leur procédé de préparation et les compositions pharmaceutiques les renfermant
EP0418933A1 (fr) Dérivés d'alcadiènes, leurs préparations, les médicaments les contenant et produits intermédiaires
EP0002978B1 (fr) Dérivés de thiazolidinedione-2,4, leur préparation et leur application en thérapeutique
FR2611718A1 (fr) Analogues d'amino prostaglandines 7-oxabicycloheptane substitues, a action therapeutique
EP0486385B1 (fr) Dérivés d'imidazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP0638568B1 (fr) Pipérazines substituées, leur procédé de préparation et les compositions pharmaceutiques les contenant
WO1990003972A1 (fr) Derives de methyl-4 ((phenyl-4 piperazinyl-1)-2 ethyl)-5 thiazole
EP0173585B1 (fr) Médicaments à base de dérivés de la pipéridine, nouveaux dérivés de la pipéridine et leurs procédés de préparation
EP0220112B1 (fr) Dérivés aromatiques substitués par un groupement (oméga-amino) alcanol à activité antimicrobienne, leur préparation et les compositions les contenant
US4221803A (en) Substituted dibenzyl ethers and pharmaceutical compositions containing said ethers for the treatment of infections
EP0037344A1 (fr) Amino-alcoxy pyrazoles, procédé pour leur préparation, et médicaments les contenant
BE897473A (fr) Nouveaux alcaloides de l'ergot de seigle leur preparation et leur utilisation comme medicaments
EP0426557B1 (fr) Procédé de préparation de (pyridyl-3)-2 tétrahydrothiopyrannecarbothioamide-2-oxydes-1-(1R,2R), les (pyridyl-3)-2 tétrahydrothiopyrannecarbothioamide-2-oxydes-1-(1R,2R) ainsi obtenus et les compositions pharmaceutiques qui les contiennent
EP0065908B1 (fr) ((Alkyl- et alcényl-3 pipéridyl-4)-2 éthyl)-3 indoles et leur utilisation comme médicaments
EP0412898A1 (fr) Nouveaux dérivés d'oxazolo pyridines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP1131293A1 (fr) Derives de 1-aminoethylquinoleine pour le traitement de l'incontinence urinaire
BE883665A (fr) Nouveaux derives du benzymidazole
EP0288647B1 (fr) Dérivés du [(pyrrolidinyl-1)-2éthoxy]-5 p-cymène, le procédé de préparation desdits dérivés et les médicaments contenant lesdits dérivés

Legal Events

Date Code Title Description
SPCF Supplementary protection certificate filed

Free format text: OICM 49586 49587 49588/920727

SPCF Supplementary protection certificate filed

Free format text: OICM 49586,49587,49588/920727, 951208

SPCG Supplementary protection certificate granted

Free format text: OICM 49586,49587,49588/920727, 951208, EXPIRES:20040515

PL Patent ceased