CH637993A5 - Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione - Google Patents

Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione Download PDF

Info

Publication number
CH637993A5
CH637993A5 CH234077A CH234077A CH637993A5 CH 637993 A5 CH637993 A5 CH 637993A5 CH 234077 A CH234077 A CH 234077A CH 234077 A CH234077 A CH 234077A CH 637993 A5 CH637993 A5 CH 637993A5
Authority
CH
Switzerland
Prior art keywords
dione
mycobacterium
androst
steroid
carbon atoms
Prior art date
Application number
CH234077A
Other languages
German (de)
English (en)
Inventor
Merle Gene Wovcha
Candice Brenda Biggs
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CH637993A5 publication Critical patent/CH637993A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CH234077A 1976-03-01 1977-02-24 Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione CH637993A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66256376A 1976-03-01 1976-03-01

Publications (1)

Publication Number Publication Date
CH637993A5 true CH637993A5 (en) 1983-08-31

Family

ID=24658223

Family Applications (2)

Application Number Title Priority Date Filing Date
CH234077A CH637993A5 (en) 1976-03-01 1977-02-24 Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
CH718582A CH638563A5 (en) 1976-03-01 1982-12-09 Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH718582A CH638563A5 (en) 1976-03-01 1982-12-09 Process for the preparation of a mixture of androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione

Country Status (9)

Country Link
JP (1) JPS60133884A (xx)
CH (2) CH637993A5 (xx)
DD (1) DD130789A5 (xx)
DE (1) DE2703645C3 (xx)
FR (1) FR2345464A1 (xx)
IL (3) IL51370A (xx)
MX (3) MX6933E (xx)
NL (1) NL170435C (xx)
PL (2) PL113212B1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293645A (en) * 1976-03-01 1981-10-06 The Upjohn Company Process for preparing androsta-1,4-diene-3,17-dione and androst-4-ene-3,17-dione
NL189865C (nl) * 1976-10-22 1993-08-16 Upjohn Co Werkwijze voor het bereiden van androst-4-een-3,17-dion en de daarbij toegepaste micro-organismen.
US4293646A (en) * 1978-08-07 1981-10-06 The Upjohn Company Composition of matter and process
DE3521111A1 (de) * 1985-06-10 1986-12-11 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 4-androsten-3,17-dion und 1,4-androstadien-3,17-dion
DE3544662A1 (de) * 1985-12-13 1987-06-19 Schering Ag Verfahren zur herstellung von 4-androsten-3,17-dion und 1,4-androstadien-3,17-dion
CN106282080B (zh) * 2016-08-10 2019-09-03 江南大学 一种新金色分枝杆菌来源的甾酮c27-单加氧酶及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1494461A (fr) * 1965-09-23 1967-09-08 Richter Gedeon Vegyeszet Procédé de préparation de stéroïdes ayant une structure de 1, 4-diène-3, 17-diones
FR1497292A (fr) * 1965-10-22 1967-10-06 Koninklijke Gist Spiritus Procédé pour l'obtention de stéroïdes ne contenant pas de substituant earboné en position 17
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
NL185574C (nl) * 1975-06-06 1990-05-16 Mitsubishi Chem Ind Werkwijze voor de microbiologische bereiding van 17-hydroxyandrosta-1,4-dieen-3-on en androsta-1,4-dieen-3,17-dion.

Also Published As

Publication number Publication date
IL60476A (en) 1981-06-29
FR2345464A1 (fr) 1977-10-21
IL51370A0 (en) 1977-04-29
NL170435B (nl) 1982-06-01
DE2703645C3 (de) 1981-11-12
DE2703645B2 (de) 1980-08-07
JPS60133884A (ja) 1985-07-17
CH638563A5 (en) 1983-09-30
NL170435C (nl) 1982-11-01
IL51370A (en) 1981-06-29
MX4503E (es) 1982-05-24
PL113212B1 (en) 1980-11-29
NL7701346A (nl) 1977-09-05
DD130789A5 (de) 1978-05-03
IL60476A0 (en) 1980-09-16
FR2345464B1 (xx) 1982-06-04
PL111029B1 (en) 1980-08-30
MX6932E (es) 1986-12-05
PL196355A1 (pl) 1978-01-02
DE2703645A1 (de) 1977-09-08
JPS6141547B2 (xx) 1986-09-16
MX6933E (es) 1986-12-05

Similar Documents

Publication Publication Date Title
DE2647895C3 (de) Verfahren zur Herstellung von 9à -Hydroxyandrostendion auf mikrobiologische Weise
US4029549A (en) Process of producing 9α-hydroxy-3-ketobisnorchol-4-en-22-oic with mycobacterium fortuitum
DE3876769T2 (de) Mikrobiologische herstellung von 9-alpha-hydroxy-17-keto-steroiden.
US4339539A (en) Biologically pure culture of mutant mycobacterium
DE2703645C3 (de) Verfahren zur Herstellung eines Gemischs aus Androsta-1,4-dien-3,17-dion und Androst-4-en-3,17-dion
DE2660114C2 (de) Verfahren zur Herstellung neuer 7 a ß-Methylhexahydro-l,(5>-indan (di)on-Verbindungen unter Verwendung von Mikroorganismus-Mutanten
DE2746323C2 (de) Verfahren zur Herstellung von 3a α-H-4α-[3'-Propionsäure]-7a β-methylhexahydro-1,5-indandion
DE2660011C2 (de) Unter Verwendung von Mikroorganismus-Mutanten durchgeführtes Verfahren zur Herstellung neuer 7 a ß - Methylhexahydro-1,(5)indan(di)on-Verbindungen
DE2802524C2 (de) Verfahren zur Herstellung von 3a alpha- H-4alpha- eckige Klammer auf 3'-Propanol eckige Klammer zu -7abeta-methylhexahydro- 1,5-indandion-hemiketal
DE2746383C2 (de) Verfahren zur mikrobiologischen Herstellung von Androst-4-en-3,17-dion
DE3215065A1 (de) Einstufiges fermentationsverfahren zur herstellung von 9-hydroxy-3-oxo-4,17(20)-pregnadien-20-carbonsaeure und dabei verwendete mikroorganismus-mutante
US4062880A (en) 9α-Hydroxy-bis-nor-cholanic acid
US4293646A (en) Composition of matter and process
US4345030A (en) Microorganism mutant conversion of sterols to androsta-4-ene-3,17-dione
US4443541A (en) Process for preparing an indenedione and a mycobacterium culture therefor

Legal Events

Date Code Title Description
PL Patent ceased