CH637105A5 - Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes - Google Patents

Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes Download PDF

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Publication number
CH637105A5
CH637105A5 CH624077A CH624077A CH637105A5 CH 637105 A5 CH637105 A5 CH 637105A5 CH 624077 A CH624077 A CH 624077A CH 624077 A CH624077 A CH 624077A CH 637105 A5 CH637105 A5 CH 637105A5
Authority
CH
Switzerland
Prior art keywords
phenyl
propoxy
hydroxy
hydrochloride
ethanol
Prior art date
Application number
CH624077A
Other languages
German (de)
English (en)
Inventor
Werner Dr Fritsch
Ulrich Dr Stache
Ernst Prof Dr Lindner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH637105A5 publication Critical patent/CH637105A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
CH624077A 1976-05-25 1977-05-20 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes CH637105A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2623314A DE2623314C2 (de) 1976-05-25 1976-05-25 1-Aryloxy-2-Hydroxy-3-aminopropane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CH637105A5 true CH637105A5 (en) 1983-07-15

Family

ID=5978907

Family Applications (5)

Application Number Title Priority Date Filing Date
CH624077A CH637105A5 (en) 1976-05-25 1977-05-20 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655781A CH640507A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655481A CH637107A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655581A CH637108A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655681A CH637109A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes

Family Applications After (4)

Application Number Title Priority Date Filing Date
CH655781A CH640507A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655481A CH637107A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655581A CH637108A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH655681A CH637109A5 (en) 1976-05-25 1981-10-13 Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes

Country Status (18)

Country Link
JP (1) JPS5312827A (nl)
AT (1) AT354421B (nl)
AU (1) AU511704B2 (nl)
BE (1) BE855041A (nl)
CA (1) CA1108633A (nl)
CH (5) CH637105A5 (nl)
DE (1) DE2623314C2 (nl)
DK (1) DK227177A (nl)
ES (1) ES458957A1 (nl)
FI (1) FI67698C (nl)
FR (1) FR2353520A1 (nl)
GB (1) GB1577670A (nl)
HU (1) HU179198B (nl)
IL (1) IL52148A (nl)
IT (1) IT1077193B (nl)
NL (1) NL7705587A (nl)
SE (1) SE440903B (nl)
ZA (1) ZA773120B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2415622A1 (fr) * 1978-01-25 1979-08-24 Lipha Amino alcools derives de l'ortho-hydroxy cinnamate de methyle applicables notamment comme medicaments
DE2824764A1 (de) * 1978-06-06 1979-12-20 Hoechst Ag Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung
DE2961251D1 (en) * 1978-08-15 1982-01-14 Smithkline Beckman Corp A method of preparing a 2-hydroxy-3-isopropyl or a 2-hydroxy-3-tert-butylaminopropyl aromatic ether
FR2459235A1 (fr) * 1979-06-14 1981-01-09 Sanofi Sa Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
JPH0629833B2 (ja) * 1984-06-15 1994-04-20 株式会社島津製作所 疲労試験機
GB8603120D0 (en) * 1986-02-07 1986-03-12 Pfizer Ltd Anti-dysrhythmia agents
CA2716369C (en) 1999-05-24 2013-05-14 Mitsubishi Tanabe Pharma Corporation Phenoxypropylamine compounds
DE19941657A1 (de) * 1999-09-01 2001-03-08 Schwabe Willmar Gmbh & Co Zimtsäurenitrile, Verfahren zu ihrer Herstellung und Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
FR2132570B1 (nl) * 1971-04-09 1974-08-02 Lipha
BE791650R (fr) * 1971-11-18 1973-05-21 Ici Ltd Derives d'alkanolamines.
ES411826A1 (es) * 1973-02-20 1976-01-01 Liade Sa Lab Procedimiento de obtencion de 1-ariloxi - 2 - propanolami- nas farmacologicamente activos.

Also Published As

Publication number Publication date
ATA370177A (de) 1979-06-15
IT1077193B (it) 1985-05-04
NL7705587A (nl) 1977-11-29
JPS6214545B2 (nl) 1987-04-02
ZA773120B (en) 1978-04-26
FI67698C (fi) 1985-05-10
CA1108633A (en) 1981-09-08
AU2543477A (en) 1978-11-30
CH637109A5 (en) 1983-07-15
BE855041A (fr) 1977-11-25
AU511704B2 (en) 1980-09-04
DE2623314A1 (de) 1977-12-08
JPS5312827A (en) 1978-02-04
FR2353520A1 (fr) 1977-12-30
AT354421B (de) 1979-01-10
SE440903B (sv) 1985-08-26
HU179198B (en) 1982-09-28
CH637107A5 (en) 1983-07-15
SE7706059L (sv) 1977-11-26
DE2623314C2 (de) 1984-08-02
IL52148A0 (en) 1977-07-31
FI771630A (nl) 1977-11-26
GB1577670A (en) 1980-10-29
ES458957A1 (es) 1978-07-16
FI67698B (fi) 1985-01-31
IL52148A (en) 1982-07-30
CH640507A5 (en) 1984-01-13
DK227177A (da) 1977-11-26
FR2353520B1 (nl) 1980-07-25
CH637108A5 (en) 1983-07-15

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PL Patent ceased