CH636845A5 - N(1)-acyl-2-hydroxy-1,3-diaminopropane, verfahren zur herstellung derselben und sie enthaltende arzneimittel. - Google Patents

N(1)-acyl-2-hydroxy-1,3-diaminopropane, verfahren zur herstellung derselben und sie enthaltende arzneimittel. Download PDF

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Publication number
CH636845A5
CH636845A5 CH503478A CH503478A CH636845A5 CH 636845 A5 CH636845 A5 CH 636845A5 CH 503478 A CH503478 A CH 503478A CH 503478 A CH503478 A CH 503478A CH 636845 A5 CH636845 A5 CH 636845A5
Authority
CH
Switzerland
Prior art keywords
hydroxy
diaminopropane
methyl
radical
fluorophenyl
Prior art date
Application number
CH503478A
Other languages
German (de)
English (en)
Inventor
Hans Dr Liepmann
Rolf Dr Hueschens
Wolfgang Dr Milkowski
Horst Dr Zeugner
Henning Dr Heinemann
Klaus-Ulrich Dr Wolf
Insa Dr Hell
Reinhard Dr Hempel
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772720968 external-priority patent/DE2720968C2/de
Priority claimed from DE2720915A external-priority patent/DE2720915C2/de
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of CH636845A5 publication Critical patent/CH636845A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/36Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH503478A 1977-05-10 1978-05-09 N(1)-acyl-2-hydroxy-1,3-diaminopropane, verfahren zur herstellung derselben und sie enthaltende arzneimittel. CH636845A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772720968 DE2720968C2 (de) 1977-05-10 1977-05-10 N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel
DE2720915A DE2720915C2 (de) 1977-05-10 1977-05-10 N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel mit diesen Verbindungen als Wirkstoff

Publications (1)

Publication Number Publication Date
CH636845A5 true CH636845A5 (de) 1983-06-30

Family

ID=25771998

Family Applications (1)

Application Number Title Priority Date Filing Date
CH503478A CH636845A5 (de) 1977-05-10 1978-05-09 N(1)-acyl-2-hydroxy-1,3-diaminopropane, verfahren zur herstellung derselben und sie enthaltende arzneimittel.

Country Status (18)

Country Link
US (2) US4191770A (it)
JP (1) JPS53141224A (it)
AT (1) AT357144B (it)
AU (1) AU520625B2 (it)
CH (1) CH636845A5 (it)
DD (1) DD135195A5 (it)
DK (1) DK201878A (it)
ES (1) ES469020A1 (it)
FR (1) FR2390422A1 (it)
GB (1) GB1585758A (it)
IE (1) IE46778B1 (it)
IL (1) IL54677A (it)
IT (1) IT1098213B (it)
NL (1) NL7805038A (it)
NO (1) NO147749C (it)
NZ (1) NZ187221A (it)
PH (1) PH14558A (it)
SU (1) SU906365A3 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459235A1 (fr) * 1979-06-14 1981-01-09 Sanofi Sa Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
JPS58177953A (ja) * 1982-04-13 1983-10-18 Eisai Co Ltd ポリプレニルカルボン酸アミドおよびその製造方法
US4596813A (en) * 1982-11-04 1986-06-24 Chevron Research Company Pyridylcarbonyl and thiocarbonyl derivatives useful as fungicides
WO1994015906A1 (en) * 1993-01-15 1994-07-21 Agouron Pharmaceuticals, Inc. Hiv protease inhibitors and their preparation
US5824821A (en) * 1997-02-07 1998-10-20 Nycomed Imaging As Process for the preparation of iodinated contrast agents and intermediates therefor
CN100387581C (zh) 1997-11-07 2008-05-14 法玛西雅厄普约翰美国公司 制备唑烷酮的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1805355A (en) * 1929-01-02 1931-05-12 Ig Farbenindustrie Ag Basic compounds and process of preparing them
US2658076A (en) * 1951-06-12 1953-11-03 Searle & Co N-dialkylaminoalkyl derivatives of alpha, beta-diarylalkanoamides and their salts
BE794424A (fr) * 1972-01-24 1973-07-23 Science Union & Cie Nouveaux dibenzocycloheptenes, leur procede d'obtention et leur application comme medicament
DE2265371C3 (de) * 1972-05-03 1980-12-11 Kali-Chemie Ag, 3000 Hannover N-(3-Benzoylaminopropyl)-aniline
GB1374366A (en) * 1972-07-21 1974-11-20 Science Union & Cie Propanol derivatives and a process for their preparation
GB1436593A (en) * 1973-03-15 1976-05-19 Science Union & Cie N-substituted acetamides processes for their preparation and pharmaceutical compositions containing them apparatus for processing photograp
DE2314993A1 (de) * 1973-03-26 1974-10-03 Kali Chemie Pharma Gmbh Neue benzodiazepinderivate und verfahren zu deren herstellung
US4141987A (en) * 1974-06-05 1979-02-27 Imperial Chemical Industries Limited 1-Aryloxy-3-thenamidoalkylamino-2-propanol derivatives
DE2448259A1 (de) * 1974-10-10 1976-04-22 Kali Chemie Pharma Gmbh Verfahren zur herstellung von 2-halogenmethyl-1,4-benzodiazepinen
US4144343A (en) * 1978-01-04 1979-03-13 Merck & Co., Inc. Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines

Also Published As

Publication number Publication date
JPS53141224A (en) 1978-12-08
DK201878A (da) 1979-02-14
IL54677A (en) 1981-02-27
NL7805038A (nl) 1978-11-14
IE46778B1 (en) 1983-09-21
NZ187221A (en) 1980-12-19
IT7823159A0 (it) 1978-05-09
DD135195A5 (de) 1979-04-18
NO781631L (no) 1978-11-13
FR2390422B1 (it) 1980-07-18
AU3594178A (en) 1979-11-15
US4402981A (en) 1983-09-06
NO147749B (no) 1983-02-28
PH14558A (en) 1981-09-24
US4191770A (en) 1980-03-04
IE780921L (en) 1978-11-10
ATA335178A (de) 1979-11-15
AU520625B2 (en) 1982-02-11
FR2390422A1 (fr) 1978-12-08
IT1098213B (it) 1985-09-07
IL54677A0 (en) 1978-07-31
JPS6252740B2 (it) 1987-11-06
GB1585758A (en) 1981-03-11
SU906365A3 (ru) 1982-02-15
ES469020A1 (es) 1979-09-01
NO147749C (no) 1983-06-08
AT357144B (de) 1980-06-25

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