CH635095A5 - (+,-)-cis-alpha-(3-(2,6-Dimethyl-1-piperidinyl)propyl)-alpha-pheny l-2-pyridylmethanol compounds - Google Patents

(+,-)-cis-alpha-(3-(2,6-Dimethyl-1-piperidinyl)propyl)-alpha-pheny l-2-pyridylmethanol compounds Download PDF

Info

Publication number
CH635095A5
CH635095A5 CH177978A CH177978A CH635095A5 CH 635095 A5 CH635095 A5 CH 635095A5 CH 177978 A CH177978 A CH 177978A CH 177978 A CH177978 A CH 177978A CH 635095 A5 CH635095 A5 CH 635095A5
Authority
CH
Switzerland
Prior art keywords
cis
dimethyl
propyl
alpha
piperidinyl
Prior art date
Application number
CH177978A
Other languages
German (de)
English (en)
Inventor
Robert Willerton Fleming
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,203 external-priority patent/US4112103A/en
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of CH635095A5 publication Critical patent/CH635095A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH177978A 1977-02-25 1978-02-17 (+,-)-cis-alpha-(3-(2,6-Dimethyl-1-piperidinyl)propyl)-alpha-pheny l-2-pyridylmethanol compounds CH635095A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/772,203 US4112103A (en) 1976-04-15 1977-02-25 Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols

Publications (1)

Publication Number Publication Date
CH635095A5 true CH635095A5 (en) 1983-03-15

Family

ID=25094280

Family Applications (1)

Application Number Title Priority Date Filing Date
CH177978A CH635095A5 (en) 1977-02-25 1978-02-17 (+,-)-cis-alpha-(3-(2,6-Dimethyl-1-piperidinyl)propyl)-alpha-pheny l-2-pyridylmethanol compounds

Country Status (11)

Country Link
JP (1) JPS53105479A (fr)
AT (1) AT358040B (fr)
BE (1) BE864033A (fr)
CA (1) CA1096382A (fr)
CH (1) CH635095A5 (fr)
DE (1) DE2806654A1 (fr)
DK (1) DK143229C (fr)
ES (1) ES467100A1 (fr)
FR (1) FR2381761A1 (fr)
GB (1) GB1581096A (fr)
PH (1) PH13125A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818914B2 (ja) * 1991-04-05 1998-10-30 シャープ株式会社 多目的スチーム発生器

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (fr) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K Nouveaux butanols tertiaires a constituants basiques

Also Published As

Publication number Publication date
JPS6257632B2 (fr) 1987-12-02
FR2381761B1 (fr) 1982-03-26
DK143229B (da) 1981-07-27
FR2381761A1 (fr) 1978-09-22
DE2806654C2 (fr) 1987-07-16
AT358040B (de) 1980-08-11
GB1581096A (en) 1980-12-10
DK143229C (da) 1981-11-30
PH13125A (en) 1979-12-12
CA1096382A (fr) 1981-02-24
ATA117078A (de) 1980-01-15
DE2806654A1 (de) 1978-08-31
BE864033A (fr) 1978-06-16
JPS53105479A (en) 1978-09-13
ES467100A1 (es) 1978-11-01
DK73278A (da) 1978-08-26

Similar Documents

Publication Publication Date Title
DE3026201C2 (fr)
DD155615A5 (de) Verfahren zur herstellung von derivaten des cis-4-phenyl-1,2,3,4-tetrahydro-1-nahtalinamins
DE1443599A1 (de) Ungesaettigte Amine
DE2047658C3 (de) 2-Styryl- und 2-Phenyläthinylbenzylaminderivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2162744A1 (de) 2-Alkyl-2-alkylamino-2,6-acetoxylidide, Verfahren zu deren Herstellung und deren Verwendung
DE3402060A1 (de) Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DD149511A5 (de) Verfahren zur herstellung von 9-aminoalkylfluorenen
DE2416016A1 (de) Neue 1- eckige klammer auf beta-(aminocarbonylphenoxy)-aethylamino eckige klammer zu -3- (thiazol-2-oxy)-2-propanole und ihre derivate
DE68905171T2 (de) Benzol-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die diese enthalten.
DE2463088C1 (de) Substituierte Thienylverbindungen,Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE69014930T2 (de) Aralkylamin-Verbindungen.
DE2406065A1 (de) Neue isoindolinderivate, ihre herstellung und die zusammensetzungen, die sie enthalten
CH637108A5 (en) Process for preparing novel 1-aryloxy-2-hydroxy-3-aminopropanes
CH637132A5 (de) Verfahren zur herstellung neuer piperidylidenderivate von benzoxanthenen, -thioxanthenen und -dibenzoxepinen.
CH635095A5 (en) (+,-)-cis-alpha-(3-(2,6-Dimethyl-1-piperidinyl)propyl)-alpha-pheny l-2-pyridylmethanol compounds
EP0004260B1 (fr) Dérivés quinolizidiniques et indolizidiniques substitués, leur procédé de préparation et médicaments les contenant
EP0293716A2 (fr) Polyhydrobenz(c,d)indolsulfonamides
DE1470002A1 (de) 5,6-Dihydromorphanthridinderivate
DD149664A5 (de) Verfahren zur herstellung von 1,1'-biphenyl-2-yl-alkylamin-derivaten
DE2609574A1 (de) Monosubstituiertes piperazinderivat, verfahren zu seiner herstellung und es enthaltende arzneimittel
AT256811B (de) Verfahren zur Herstellung von neuen basischen Dibenzocyclohepten-5-yl-essigsäureestern
DE2265580C2 (de) Heptamethylenimino-alkyl-xanthen-9-carbonsäureester, deren Säureadditionssalze und Verfahren zu deren Herstellung, sowie Arzneimittel, welche diese enthalten
DE2627210A1 (de) Neue benzophenonderivate
AT238181B (de) Verfahren zur Herstellung neuer Pyrrolidinverbindungen
EP0091057B1 (fr) 5,6-Dihydro-11-alkylène-morphantridin-6-ones, leur procédé de préparation et les médicaments les contenant