CH633006A5 - Process for preparing novel thromboxane analogues - Google Patents

Process for preparing novel thromboxane analogues Download PDF

Info

Publication number
CH633006A5
CH633006A5 CH466777A CH466777A CH633006A5 CH 633006 A5 CH633006 A5 CH 633006A5 CH 466777 A CH466777 A CH 466777A CH 466777 A CH466777 A CH 466777A CH 633006 A5 CH633006 A5 CH 633006A5
Authority
CH
Switzerland
Prior art keywords
methyl
dihydro
trinor
oxa
inter
Prior art date
Application number
CH466777A
Other languages
German (de)
English (en)
Inventor
William Paul Schneider
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/676,894 external-priority patent/US4018804A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CH633006A5 publication Critical patent/CH633006A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH466777A 1976-04-14 1977-04-14 Process for preparing novel thromboxane analogues CH633006A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/676,894 US4018804A (en) 1976-04-14 1976-04-14 Intermediate for synthesis of Thromboxane B2
US05/716,473 US4070384A (en) 1976-04-14 1976-08-20 Process for preparing thromboxane B compounds from prostaglandin fα co

Publications (1)

Publication Number Publication Date
CH633006A5 true CH633006A5 (en) 1982-11-15

Family

ID=27101643

Family Applications (1)

Application Number Title Priority Date Filing Date
CH466777A CH633006A5 (en) 1976-04-14 1977-04-14 Process for preparing novel thromboxane analogues

Country Status (5)

Country Link
JP (1) JPS52136119A (fr)
CH (1) CH633006A5 (fr)
DE (1) DE2715883A1 (fr)
FR (2) FR2375185A1 (fr)
GB (1) GB1534982A (fr)

Also Published As

Publication number Publication date
DE2715883A1 (de) 1977-10-27
FR2375185A1 (fr) 1978-07-21
FR2371442B1 (fr) 1981-12-24
FR2371442A1 (fr) 1978-06-16
GB1534982A (en) 1978-12-06
JPS52136119A (en) 1977-11-14

Similar Documents

Publication Publication Date Title
CH627725A5 (de) Verfahren zur herstellung neuer prostaglandin-analoga mit primaerer alkoholgruppe am c-1.
CH628028A5 (de) Verfahren zur herstellung neuer prostaglandin-analoga mit dreifachbindung zwischen c-13 und c-14.
DE2322673A1 (de) Neue verbindungen vom prostaglandintyp und verfahren zu ihrer herstellung
DE2437388A1 (de) Prostansaeurederivate
DE2355540C2 (de) 16-Phenoxy-ω-tetranorprostaglandinderivate
CH625797A5 (fr)
CH628884A5 (de) Verfahren zur herstellung neuer prostaglandin-analoga.
DE2626888A1 (de) 11-desoxy-16-aryloxy-omega-tetranorprostaglandine
DE2638827A1 (de) Neue 11-deoxy-prostaglandine e, f tief alpha und f tief beta
CH628316A5 (de) Verfahren zur herstellung neuer prostaglandin-analoga mit primaerer alkoholgruppe am c-1.
CH634831A5 (en) Process for the preparation of optically active or racemic prostaglandins.
CH627428A5 (de) Verfahren zur herstellung neuer prostaglandin-analoga mit primaerer alkoholgruppe am c-1.
CH642063A5 (de) Verfahren zur herstellung von prostaglandin-analoga, bei welchen die carbonylgruppe am c-9 durch eine methylengruppe ersetzt ist.
DE2610718A1 (de) Neue 16-phenoxy-prostaglandin-verbindungen
CH633551A5 (de) Verfahren zur herstellung von neuen thromboxan-analoga.
CH640847A5 (en) Process for preparing analogues of 5,6-dihydroprostacyclin
CH624929A5 (fr)
CH633006A5 (en) Process for preparing novel thromboxane analogues
CH630898A5 (de) Verfahren zur herstellung neuer prostaglandin-analoga mit dreifachbindung zwischen c-13 und c-14.
DE2542686A1 (de) 2a,2b-dihomo-15-methyl- und -15- aethyl-pgf-und pge-verbindungen und verfahren zu deren herstellung
CH630897A5 (en) Process for preparing novel prostaglandin analogues having a triple bond between C-13 and C-14.
CH624100A5 (fr)
DE2355042A1 (de) Neue prostaglandinanaloge und verfahren zu deren herstellung
DE2121980C3 (de) Epimere 15-Methyl-15(S)- und 15-Me thyl- 15(R)-Prostansäurederi vate, Verfahren zu ihrer Herstellung sowie pharmazeutische Zubereitungen
DE2601260A1 (de) 11-deoxy-17-phenyl-18,19,20-trinor- prostaglandin-verbindungen

Legal Events

Date Code Title Description
PL Patent ceased