CH628907A5 - Process for the preparation of 24,25-dihydroxycholesterol derivatives - Google Patents
Process for the preparation of 24,25-dihydroxycholesterol derivatives Download PDFInfo
- Publication number
- CH628907A5 CH628907A5 CH1224676A CH1224676A CH628907A5 CH 628907 A5 CH628907 A5 CH 628907A5 CH 1224676 A CH1224676 A CH 1224676A CH 1224676 A CH1224676 A CH 1224676A CH 628907 A5 CH628907 A5 CH 628907A5
- Authority
- CH
- Switzerland
- Prior art keywords
- hydroxy
- methoxy
- mixture
- cyclo
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/621,319 US3994878A (en) | 1975-10-10 | 1975-10-10 | Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof |
| US05/623,859 US4038272A (en) | 1975-10-20 | 1975-10-20 | Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH628907A5 true CH628907A5 (en) | 1982-03-31 |
Family
ID=27088923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1224676A CH628907A5 (en) | 1975-10-10 | 1976-09-28 | Process for the preparation of 24,25-dihydroxycholesterol derivatives |
Country Status (8)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH644873A5 (de) * | 1980-02-12 | 1984-08-31 | Hoffmann La Roche | Verfahren zur herstellung von cholesterinderivaten. |
| RS58166B1 (sr) | 2013-03-13 | 2019-03-29 | Sage Therapeutics Inc | Neuroaktivni steroidi i postupci za njihovu upotrebu |
| CN113501855A (zh) | 2015-07-06 | 2021-10-15 | 萨奇治疗股份有限公司 | 氧甾醇及其使用方法 |
| AU2016289965B2 (en) * | 2015-07-06 | 2021-09-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| PT3436022T (pt) | 2016-04-01 | 2022-07-04 | Sage Therapeutics Inc | Oxisteróis e métodos de utilização dos mesmos |
| US10752653B2 (en) | 2016-05-06 | 2020-08-25 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| MA45598B1 (fr) | 2016-07-07 | 2021-09-30 | Sage Therapeutics Inc | Stéroles 24-hydroxylés substitués en position 11 pour le traitement des maladies liées au récepteur nmda |
| AU2017337121B2 (en) | 2016-09-30 | 2022-01-27 | Sage Therapeutics, Inc. | C7 substituted oxysterols and methods as NMDA modulators |
| IL266093B2 (en) | 2016-10-18 | 2024-02-01 | Sage Therapeutics Inc | Oxysterols and methods of using them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7402846A (US20080293856A1-20081127-C00127.png) * | 1973-03-02 | 1974-09-04 | ||
| US3822254A (en) * | 1973-05-21 | 1974-07-02 | Hoffmann La Roche | Synthesis of 25-hydroxycholesterol |
-
1976
- 1976-09-28 CH CH1224676A patent/CH628907A5/de not_active IP Right Cessation
- 1976-10-08 JP JP12050076A patent/JPS5246061A/ja active Pending
- 1976-10-08 NL NL7611155A patent/NL7611155A/xx not_active Application Discontinuation
- 1976-10-08 GB GB4193876A patent/GB1564806A/en not_active Expired
- 1976-10-08 IT IT2816476A patent/IT1068692B/it active
- 1976-10-08 GB GB2314077A patent/GB1564808A/en not_active Expired
- 1976-10-08 GB GB2313977A patent/GB1564807A/en not_active Expired
- 1976-10-08 GB GB2314277A patent/GB1564810A/en not_active Expired
- 1976-10-08 GB GB2314177A patent/GB1564809A/en not_active Expired
- 1976-10-08 AT AT751376A patent/AT355236B/de not_active IP Right Cessation
- 1976-10-08 DE DE19762645527 patent/DE2645527A1/de not_active Ceased
- 1976-10-11 FR FR7630450A patent/FR2407941A1/fr active Granted
-
1977
- 1977-04-22 FR FR7712223A patent/FR2351998A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5246061A (en) | 1977-04-12 |
| NL7611155A (nl) | 1977-04-13 |
| AT355236B (de) | 1980-02-25 |
| FR2407941B1 (US20080293856A1-20081127-C00127.png) | 1980-05-16 |
| FR2407941A1 (fr) | 1979-06-01 |
| FR2351998B1 (US20080293856A1-20081127-C00127.png) | 1980-04-25 |
| GB1564809A (en) | 1980-04-16 |
| GB1564808A (en) | 1980-04-16 |
| DE2645527A1 (de) | 1977-04-21 |
| ATA751376A (de) | 1979-07-15 |
| GB1564807A (en) | 1980-04-16 |
| FR2351998A1 (fr) | 1977-12-16 |
| IT1068692B (it) | 1985-03-21 |
| GB1564810A (en) | 1980-04-16 |
| GB1564806A (en) | 1980-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |