CH625252A5 - - Google Patents

Download PDF

Info

Publication number
CH625252A5
CH625252A5 CH1448176A CH1448176A CH625252A5 CH 625252 A5 CH625252 A5 CH 625252A5 CH 1448176 A CH1448176 A CH 1448176A CH 1448176 A CH1448176 A CH 1448176A CH 625252 A5 CH625252 A5 CH 625252A5
Authority
CH
Switzerland
Prior art keywords
demethoxy
adriamycin
day
hydrogen
demethoxyadriamycin
Prior art date
Application number
CH1448176A
Other languages
German (de)
English (en)
Inventor
Frederico Arcamone
Luigi Bernardi
Pietro Giardino
Aurelio Di Marco
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of CH625252A5 publication Critical patent/CH625252A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH1448176A 1975-11-18 1976-11-17 CH625252A5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47559/75A GB1511680A (en) 1975-11-18 1975-11-18 Daunosaminyl anthracyclinones

Publications (1)

Publication Number Publication Date
CH625252A5 true CH625252A5 (xx) 1981-09-15

Family

ID=10445422

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1448176A CH625252A5 (xx) 1975-11-18 1976-11-17

Country Status (17)

Country Link
US (1) US4125607A (xx)
JP (1) JPS5262269A (xx)
AT (1) AT349633B (xx)
AU (1) AU499514B2 (xx)
BE (1) BE848407A (xx)
CA (1) CA1072546A (xx)
CH (1) CH625252A5 (xx)
DE (1) DE2652391C3 (xx)
DK (1) DK146542C (xx)
FR (1) FR2347047A1 (xx)
GB (1) GB1511680A (xx)
HK (1) HK1282A (xx)
MY (1) MY8400400A (xx)
NL (1) NL178692C (xx)
SE (1) SE7612752L (xx)
SU (1) SU727148A3 (xx)
ZA (1) ZA766851B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1535080A (en) * 1976-08-12 1978-12-06 Farmaceutici Italia Naphthacenequinone derivatives
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4585760A (en) * 1981-07-16 1986-04-29 American Cyanamid Company Dimethylfurano heterocyclic analogs of daunomycin
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの4−デメトキシ−3′−デアミノ−3′(4−モリホリニル)誘導体
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
JPS60188149A (ja) * 1984-03-07 1985-09-25 中松 義郎 人体冷却装置
EP0183691A1 (en) * 1984-06-14 1986-06-11 Biogal Gyogyszergyar Process for preparing adriamycine and halide salts thereof
GB2169285A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxydoxorubicin-14-esters
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters
US4663445A (en) * 1985-03-20 1987-05-05 The Ohio State Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics
JPS6272356A (ja) * 1985-09-25 1987-04-02 松下電工株式会社 眼治療器
IE64781B1 (en) 1987-03-11 1995-09-06 Erba Carlo Spa Immunoglobulin conjugates
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
DK2991993T3 (en) * 2013-04-29 2018-07-30 Nerviano Medical Sciences Srl NEW MORPHOLINYLANTHRACYCLINE DERIVATIVES
CN107001384A (zh) * 2014-11-05 2017-08-01 内尔维阿诺医学科学有限公司 官能化的吗啉基蒽环类衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260438C3 (de) * 1972-12-11 1980-01-10 Societa Farmaceutici Italia, Mailand (Italien) Adriamycinester und deren Salze, Verfahren zu deren Herstellung und Arzneimittel
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1499026A (en) * 1975-06-20 1978-01-25 Farmaceutici Italia Adriamycin esters

Also Published As

Publication number Publication date
MY8400400A (en) 1984-12-31
FR2347047A1 (fr) 1977-11-04
BE848407A (fr) 1977-05-17
NL7612389A (nl) 1977-05-23
HK1282A (en) 1982-01-22
DE2652391A1 (de) 1977-05-26
DE2652391C3 (de) 1982-04-08
AT349633B (de) 1979-04-10
ATA849076A (de) 1978-09-15
NL178692B (nl) 1985-12-02
JPS5736919B2 (xx) 1982-08-06
SU727148A3 (ru) 1980-04-05
FR2347047B1 (xx) 1980-03-14
DE2652391B2 (de) 1981-05-21
SE7612752L (sv) 1977-05-19
AU499514B2 (en) 1979-04-26
ZA766851B (en) 1978-06-28
AU1964376A (en) 1978-05-25
US4125607A (en) 1978-11-14
DK513076A (da) 1977-05-19
JPS5262269A (en) 1977-05-23
CA1072546A (en) 1980-02-26
NL178692C (nl) 1986-05-01
GB1511680A (en) 1978-05-24
DK146542B (da) 1983-10-31
DK146542C (da) 1984-04-09

Similar Documents

Publication Publication Date Title
DE2525633C3 (xx)
CH625252A5 (xx)
DE3609052C2 (de) Anthracyclinglykoside, Verfahren zu ihrer Herstellung und sie enthaltende Zubereitungen
DE2819217A1 (de) Neue antitumoranthracycline
DE3031732A1 (de) Stoffzusammensetzung insbesondere zur bekaempfung boesartiger geschwuelste
EP0263956B1 (de) Cis-Platin-Komplexe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Mittel
DE2530416A1 (de) Alkylaminoglucopyranosid-derivate und verfahren zu ihrer herstellung
DE1445186C3 (de) 3,3'-Di-2-imidazolin-2-yl-carbanilid
DE2804099A1 (de) Carminomycinderivate, verfahren zu ihrer herstellung und ihre verwendung
CH668970A5 (de) 5-pyrimidincarboxamide, die fuer die behandlung von leukaemie und tumoren verwendbar sind.
DE2641388C3 (de) 3',4'-Didesoxykanamycin B-N-methansulfonsäuren und deren Alkalimetallsalze sowie diese Verbindungen enthaltende pharmazeutische Präparate
DE2819216A1 (de) Neue anthracyclinanaloga
DE2830007B2 (de) Inosadiaminderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Antitumormittel
DE2735455B2 (de) Daunomycinanaloga, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3428945A1 (de) 4'-halogenanthracyclinglykoside, verfahren zu deren herstellung und diese enthaltende pharmazeutische zubereitung
CH636874A5 (de) Verfahren zur herstellung von neuen 5-fluoruracilderivaten und nach dem verfahren hergestellte 5-fluoruracilderivate.
DE2833507A1 (de) 1-(5-fluorurazilyl-1)-2,5-di-0-acetyl- beta -d-glucofuranurono-6,3-lakton
DE2825445A1 (de) Rifamycin-verbindungen
DE2921844A1 (de) Neue nitrosoharnstoff-verbindungen, ein verfahren zu deren herstellung sowie therapeutische zubereitung
DE2738498A1 (de) Neue nitrosoharnstoffderivate
DE2230003A1 (de) Neue nitrosoharnstoffderivate
DE3037884C2 (de) (13-Daunorubicin)-(N-oxyl-2,2,6,6-tetramethylpiperidin-4-on)-azin-hydrochlorid und Verfahren zu seiner Herstellung
DE609151C (de) Verfahren zur Darstellung von Aminoalkoholen mit sekundaerer oder tertiaerer Aminogruppe
AT390065B (de) Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
AT337199B (de) Verfahren zur herstellung von neuen, tricyclischen kondensierten imidazol-derivaten

Legal Events

Date Code Title Description
PL Patent ceased